SG11202001564QA - Methods of reducing particle formation and compositions formed thereby - Google Patents

Methods of reducing particle formation and compositions formed thereby

Info

Publication number
SG11202001564QA
SG11202001564QA SG11202001564QA SG11202001564QA SG11202001564QA SG 11202001564Q A SG11202001564Q A SG 11202001564QA SG 11202001564Q A SG11202001564Q A SG 11202001564QA SG 11202001564Q A SG11202001564Q A SG 11202001564QA SG 11202001564Q A SG11202001564Q A SG 11202001564QA
Authority
SG
Singapore
Prior art keywords
methods
particle formation
compositions formed
reducing particle
reducing
Prior art date
Application number
SG11202001564QA
Other languages
English (en)
Inventor
Mayank Patel
Stacy Wasinger
Danya Spritzer
Xiaolin Tang
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of SG11202001564QA publication Critical patent/SG11202001564QA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
SG11202001564QA 2017-09-19 2018-08-10 Methods of reducing particle formation and compositions formed thereby SG11202001564QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762560365P 2017-09-19 2017-09-19
PCT/US2018/046183 WO2019060062A1 (en) 2017-09-19 2018-08-10 METHODS OF REDUCING PARTICLE FORMATION AND COMPOSITIONS FORMED THEREFROM

Publications (1)

Publication Number Publication Date
SG11202001564QA true SG11202001564QA (en) 2020-04-29

Family

ID=63449670

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202001564QA SG11202001564QA (en) 2017-09-19 2018-08-10 Methods of reducing particle formation and compositions formed thereby

Country Status (14)

Country Link
US (1) US20190083618A1 (zh)
EP (1) EP3684415A1 (zh)
JP (2) JP7301043B2 (zh)
KR (1) KR20200054980A (zh)
CN (1) CN111201042B (zh)
AR (1) AR112536A1 (zh)
AU (1) AU2018336623B2 (zh)
BR (1) BR112020005335A2 (zh)
CA (1) CA3073935A1 (zh)
IL (2) IL272954B2 (zh)
MX (2) MX2020002850A (zh)
SG (1) SG11202001564QA (zh)
TW (1) TWI831747B (zh)
WO (1) WO2019060062A1 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020227126A1 (en) * 2019-05-03 2020-11-12 Lonza Ltd Determination of contaminants in cell-based products with flow imaging microscopy
TW202221008A (zh) * 2020-08-07 2022-06-01 瑞士商赫孚孟拉羅股份公司 製備蛋白質組成物之方法
IL310285A (en) 2021-08-13 2024-03-01 Biotest Ag Fibrinogen preparations and preparation methods
JP7367262B1 (ja) 2021-12-01 2023-10-23 中外製薬株式会社 抗体含有製剤の調製方法
WO2023215750A2 (en) 2022-05-02 2023-11-09 Regeneron Pharmaceuticals, Inc. Methods for reducing lipase activity

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4364645B2 (ja) * 2002-02-14 2009-11-18 中外製薬株式会社 抗体含有溶液製剤
GT200600031A (es) * 2005-01-28 2006-08-29 Formulacion anticuerpo anti a beta
CA2792517C (en) * 2010-03-09 2020-03-24 Janssen Biotech, Inc. Non-aqueous high concentration reduced viscosity suspension formulations
KR101835918B1 (ko) * 2011-03-28 2018-03-07 세키스이 메디칼 가부시키가이샤 Psa의 측정 방법 및 그의 시약
TW201628649A (zh) * 2014-10-09 2016-08-16 再生元醫藥公司 減少醫藥調配物中微可見顆粒之方法

Also Published As

Publication number Publication date
TWI831747B (zh) 2024-02-11
AU2018336623B2 (en) 2024-05-09
EP3684415A1 (en) 2020-07-29
MX2023014446A (es) 2023-12-15
AU2018336623A1 (en) 2020-03-12
CA3073935A1 (en) 2019-03-28
IL310113A (en) 2024-03-01
BR112020005335A2 (pt) 2020-09-24
WO2019060062A1 (en) 2019-03-28
TW201914615A (zh) 2019-04-16
JP2023112046A (ja) 2023-08-10
IL272954B1 (en) 2024-02-01
IL272954A (en) 2020-04-30
MX2020002850A (es) 2020-07-24
CN111201042B (zh) 2024-05-10
US20190083618A1 (en) 2019-03-21
KR20200054980A (ko) 2020-05-20
IL272954B2 (en) 2024-06-01
JP7301043B2 (ja) 2023-06-30
JP2020534260A (ja) 2020-11-26
AR112536A1 (es) 2019-11-06
CN111201042A (zh) 2020-05-26

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