SG11202001544VA - Treatment of abnormal bone conditions in acid sphingomyelinase deficiency patients - Google Patents

Treatment of abnormal bone conditions in acid sphingomyelinase deficiency patients

Info

Publication number
SG11202001544VA
SG11202001544VA SG11202001544VA SG11202001544VA SG11202001544VA SG 11202001544V A SG11202001544V A SG 11202001544VA SG 11202001544V A SG11202001544V A SG 11202001544VA SG 11202001544V A SG11202001544V A SG 11202001544VA SG 11202001544V A SG11202001544V A SG 11202001544VA
Authority
SG
Singapore
Prior art keywords
treatment
abnormal bone
acid sphingomyelinase
bone conditions
sphingomyelinase deficiency
Prior art date
Application number
SG11202001544VA
Other languages
English (en)
Inventor
Ana Cristina Scheidt-Puga
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of SG11202001544VA publication Critical patent/SG11202001544VA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/465Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/04Phosphoric diester hydrolases (3.1.4)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
SG11202001544VA 2017-08-24 2018-08-22 Treatment of abnormal bone conditions in acid sphingomyelinase deficiency patients SG11202001544VA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762549732P 2017-08-24 2017-08-24
EP17306720 2017-12-07
PCT/IB2018/056346 WO2019038685A2 (en) 2017-08-24 2018-08-22 TREATMENT OF ABNORMAL BONE CONDITIONS IN PATIENTS WITH ACIDIC SPHINGOMYELASE DISEASE

Publications (1)

Publication Number Publication Date
SG11202001544VA true SG11202001544VA (en) 2020-03-30

Family

ID=63556374

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202001544VA SG11202001544VA (en) 2017-08-24 2018-08-22 Treatment of abnormal bone conditions in acid sphingomyelinase deficiency patients

Country Status (16)

Country Link
US (1) US11898175B2 (ko)
EP (1) EP3672622B1 (ko)
JP (3) JP7216075B2 (ko)
KR (1) KR20200044064A (ko)
CN (1) CN111344003B (ko)
AU (1) AU2018319565A1 (ko)
BR (1) BR112020003541A2 (ko)
CA (1) CA3073648A1 (ko)
CO (1) CO2020001801A2 (ko)
ES (1) ES2970423T3 (ko)
IL (1) IL272757B1 (ko)
MX (2) MX2020002106A (ko)
PL (1) PL3672622T3 (ko)
SG (1) SG11202001544VA (ko)
TW (1) TWI791040B (ko)
WO (1) WO2019038685A2 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY38238A (es) * 2018-05-25 2019-12-31 Genzyme Corp Composiciones farmacéuticas para el tratamiento de la deficiencia de esfingomielinasa ácida
CA3140183A1 (en) * 2019-05-31 2020-12-03 Genzyme Corporation Two-dimensional lc-ms/ms systems
CN112773779B (zh) * 2021-02-04 2022-08-16 上海交通大学医学院附属新华医院 氨溴索、千金藤和汉防已在治疗酸性鞘磷脂酶缺乏症中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5773278A (en) 1991-05-03 1998-06-30 Mount Sinai Medical Center Acid sphingomyelinase gene
CN1302897A (zh) 1999-10-28 2001-07-11 上海博容基因开发有限公司 一种新的多肽——人酸性鞘磷酯酶相似的磷酸二酯酶21和编码这种多肽的多核苷酸
WO2006130769A2 (en) * 2005-06-02 2006-12-07 Tercica, Inc. Methods for treatment of growth disorders
HRP20211992T1 (hr) * 2009-08-28 2022-04-01 Icahn School Of Medicine At Mount Sinai Zamjenska enzimska terapija povećanjem doze za liječenje nedostatka kiseline sfingomijelinaze
KR20140138850A (ko) 2012-03-02 2014-12-04 샤이어 휴먼 지네틱 테라피즈 인크. Iii형 고셔병을 치료하기 위한 조성물 및 방법
EA201591108A1 (ru) 2012-12-12 2015-11-30 Тева Фармасьютикал Индастриз Лтд. Слитый гормон роста человека и альбумин, составы и их применения
IL298675A (en) 2013-06-07 2023-01-01 Genzyme Corp A marker for disorders of acid sphingomyelinase and its uses

Also Published As

Publication number Publication date
IL272757A (en) 2020-04-30
ES2970423T3 (es) 2024-05-28
IL272757B1 (en) 2024-03-01
JP2023052459A (ja) 2023-04-11
AU2018319565A1 (en) 2020-04-09
US11898175B2 (en) 2024-02-13
MX2020002106A (es) 2020-07-14
PL3672622T3 (pl) 2024-04-02
TW201919689A (zh) 2019-06-01
CA3073648A1 (en) 2019-02-28
BR112020003541A2 (pt) 2020-09-01
TWI791040B (zh) 2023-02-01
JP7216075B2 (ja) 2023-01-31
CN111344003B (zh) 2024-05-07
EP3672622B1 (en) 2023-11-08
WO2019038685A2 (en) 2019-02-28
CO2020001801A2 (es) 2020-04-01
CN111344003A (zh) 2020-06-26
KR20200044064A (ko) 2020-04-28
JP2020531527A (ja) 2020-11-05
EP3672622A2 (en) 2020-07-01
RU2020111649A (ru) 2021-09-24
JP7431356B2 (ja) 2024-02-14
JP2024050732A (ja) 2024-04-10
US20210139868A1 (en) 2021-05-13
MX2023010908A (es) 2023-09-27
WO2019038685A3 (en) 2019-05-02

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