SG11202001283PA - Acylated oxyntomodulin peptide analog - Google Patents
Acylated oxyntomodulin peptide analogInfo
- Publication number
- SG11202001283PA SG11202001283PA SG11202001283PA SG11202001283PA SG11202001283PA SG 11202001283P A SG11202001283P A SG 11202001283PA SG 11202001283P A SG11202001283P A SG 11202001283PA SG 11202001283P A SG11202001283P A SG 11202001283PA SG 11202001283P A SG11202001283P A SG 11202001283PA
- Authority
- SG
- Singapore
- Prior art keywords
- peptide analog
- oxyntomodulin peptide
- acylated oxyntomodulin
- acylated
- analog
- Prior art date
Links
- PXZWGQLGAKCNKD-DPNMSELWSA-N molport-023-276-326 Chemical class C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(O)=O)[C@@H](C)O)C(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 PXZWGQLGAKCNKD-DPNMSELWSA-N 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20170103798 | 2017-08-16 | ||
| KR1020180095717A KR102230363B1 (ko) | 2017-08-16 | 2018-08-16 | 아실화 옥신토모듈린 펩타이드 유사체 |
| PCT/KR2018/009425 WO2019035672A1 (ko) | 2017-08-16 | 2018-08-16 | 아실화 옥신토모듈린 펩타이드 유사체 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202001283PA true SG11202001283PA (en) | 2020-03-30 |
Family
ID=65562699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202001283PA SG11202001283PA (en) | 2017-08-16 | 2018-08-16 | Acylated oxyntomodulin peptide analog |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US11236142B2 (ar) |
| EP (2) | EP4079757A1 (ar) |
| JP (2) | JP7211659B2 (ar) |
| KR (2) | KR102230363B1 (ar) |
| CN (3) | CN117603337A (ar) |
| AU (1) | AU2018318672B2 (ar) |
| BR (1) | BR112020003319A2 (ar) |
| CA (1) | CA3073011C (ar) |
| ES (1) | ES2973986T3 (ar) |
| HR (1) | HRP20240371T1 (ar) |
| IL (1) | IL272606A (ar) |
| MX (1) | MX2020001761A (ar) |
| PH (1) | PH12020500338A1 (ar) |
| PL (1) | PL3670529T3 (ar) |
| RS (1) | RS65414B1 (ar) |
| RU (1) | RU2752787C1 (ar) |
| SA (1) | SA520411366B1 (ar) |
| SG (1) | SG11202001283PA (ar) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115916238A (zh) * | 2020-04-20 | 2023-04-04 | 韩美药品株式会社 | 包含胰高血糖素/GLP-l/GIP受体三重激动剂或其缀合物的高血脂症预防或治疗组合物及其使用方法 |
| KR102154959B1 (ko) * | 2020-04-29 | 2020-09-10 | 동아에스티 주식회사 | 지속형 glp-1 및 글루카곤 수용체 이중작용제 |
| CN115975057B (zh) * | 2023-03-16 | 2023-05-16 | 杭州信海医药科技有限公司 | 一种可妥度肽的固相合成方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7928058B2 (en) * | 2006-02-22 | 2011-04-19 | Merck Sharp & Dohme Corp. | Pharmaceutical composition comprising oxyntomodulin derivatives and a method for reducing body weight using the composition |
| CA2747112A1 (en) | 2008-12-15 | 2010-06-24 | Zealand Pharma A/S | Glucagon analogues |
| NZ593813A (en) | 2008-12-15 | 2013-02-22 | Zealand Pharma As | Glucagon analogues |
| ES2439499T3 (es) | 2008-12-15 | 2014-01-23 | Zealand Pharma A/S | Análogos de glucagón |
| WO2010096052A1 (en) * | 2009-02-19 | 2010-08-26 | Merck Sharp & Dohme Corp. | Oxyntomodulin analogs |
| AR081975A1 (es) * | 2010-06-23 | 2012-10-31 | Zealand Pharma As | Analogos de glucagon |
| NZ604208A (en) * | 2010-06-24 | 2014-10-31 | Zealand Pharma As | Glucagon analogues |
| MY164680A (en) * | 2011-06-17 | 2018-01-30 | Hanmi Science Co Ltd | A conjugate comprising oxyntomodulin and an immunoglobulin fragment, and use thereof |
| AP2014007797A0 (en) | 2011-12-23 | 2014-07-31 | Boehringer Ingelheim Int | Glucagon analogues |
| EP2838552A4 (en) * | 2012-04-19 | 2016-05-18 | Opko Biolog Ltd | OXYNTOMODULIN VARIANTS WITH EXTENDED ACTION AND PROCESSES FOR PRODUCING SAME |
| US10537646B2 (en) * | 2012-06-04 | 2020-01-21 | Opko Biologics Ltd. | Pegylated OXM variants |
| KR101968344B1 (ko) * | 2012-07-25 | 2019-04-12 | 한미약품 주식회사 | 옥신토모듈린 유도체를 포함하는 고지혈증 치료용 조성물 |
| EP2986314A4 (en) | 2013-03-15 | 2016-04-13 | Univ Indiana Res & Tech Corp | PROTOCOLS AND A PROLONGED ACTION |
| US9988429B2 (en) * | 2013-10-17 | 2018-06-05 | Zealand Pharma A/S | Glucagon analogues |
| CN104926934B (zh) * | 2014-09-23 | 2016-11-09 | 蒋先兴 | 胃泌酸调节素类似物 |
| JP6657230B2 (ja) | 2014-09-24 | 2020-03-04 | インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション | インクレチン−インスリンコンジュゲート |
| WO2016090628A1 (zh) * | 2014-12-12 | 2016-06-16 | 北京韩美药品有限公司 | 胃泌酸调节肽(oxm)类似物、其合成及应用 |
| WO2016205488A1 (en) * | 2015-06-17 | 2016-12-22 | The California Institute For Biomedical Research | Modified therapeutic agents and compositions thereof |
| WO2017160669A1 (en) * | 2016-03-18 | 2017-09-21 | Merck Sharp & Dohme Corp. | Insulin-incretin conjugates |
-
2018
- 2018-08-16 KR KR1020180095717A patent/KR102230363B1/ko active IP Right Grant
- 2018-08-16 JP JP2020508489A patent/JP7211659B2/ja active Active
- 2018-08-16 PL PL18846196.6T patent/PL3670529T3/pl unknown
- 2018-08-16 CN CN202410003809.3A patent/CN117603337A/zh active Pending
- 2018-08-16 EP EP22170622.9A patent/EP4079757A1/en active Pending
- 2018-08-16 CA CA3073011A patent/CA3073011C/en active Active
- 2018-08-16 CN CN202310958807.5A patent/CN116854804A/zh active Pending
- 2018-08-16 EP EP18846196.6A patent/EP3670529B1/en active Active
- 2018-08-16 RU RU2020108518A patent/RU2752787C1/ru active
- 2018-08-16 HR HRP20240371TT patent/HRP20240371T1/hr unknown
- 2018-08-16 RS RS20240329A patent/RS65414B1/sr unknown
- 2018-08-16 SG SG11202001283PA patent/SG11202001283PA/en unknown
- 2018-08-16 AU AU2018318672A patent/AU2018318672B2/en active Active
- 2018-08-16 MX MX2020001761A patent/MX2020001761A/es unknown
- 2018-08-16 BR BR112020003319-7A patent/BR112020003319A2/pt unknown
- 2018-08-16 US US16/638,970 patent/US11236142B2/en active Active
- 2018-08-16 CN CN201880053473.4A patent/CN111094331B/zh active Active
- 2018-08-16 ES ES18846196T patent/ES2973986T3/es active Active
-
2020
- 2020-02-11 IL IL272606A patent/IL272606A/en unknown
- 2020-02-14 PH PH12020500338A patent/PH12020500338A1/en unknown
- 2020-02-16 SA SA520411366A patent/SA520411366B1/ar unknown
- 2020-03-31 KR KR1020200039264A patent/KR102230368B1/ko active IP Right Grant
-
2021
- 2021-08-24 US US17/410,697 patent/US11713344B2/en active Active
- 2021-10-27 JP JP2021175902A patent/JP7443315B2/ja active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL275298A (en) | Mitochondria-targeted peptides | |
| HK1254601A1 (zh) | 新型肽 | |
| HK1248729A1 (zh) | 細胞毒性hexim1肽和其用途 | |
| SG11202005653RA (en) | Novel peptide | |
| IL272606A (en) | An acyl-modified peptide oxyntomodulin analog | |
| GB201719557D0 (en) | Polypeptide | |
| IL283553A (en) | Oxyntomodulin analogue peptide preparations | |
| GB201604468D0 (en) | Peptides | |
| EP3653063A4 (en) | PEPTIDE | |
| EP3480212C0 (en) | IL13RALPHA2 PEPTIDE AND ITS USES | |
| EP3725884A4 (en) | PEPTIDE CAPABLE OF CROSSING THE CELLULAR MEMBRANE | |
| GB201713700D0 (en) | Peptide conjugates | |
| GB201700557D0 (en) | Novel peptides | |
| GB201706472D0 (en) | Tumour-targeting peptide variants | |
| IL284006A (en) | Mitochondria-targeted peptides | |
| GB201612150D0 (en) | Modified peptide | |
| IL275278A (en) | Elastomeric peptide | |
| GB201719520D0 (en) | Neuroprotectvie peptide | |
| GB201715378D0 (en) | Peptides | |
| GB201715379D0 (en) | Peptides | |
| GB201711620D0 (en) | Peptides | |
| GB201707837D0 (en) | Peptides | |
| GB201717773D0 (en) | Peptide Synthesis | |
| GB201814440D0 (en) | Peptide | |
| GB201807863D0 (en) | Peptides |