SG11202000015YA - Fucosyltransferases and their use in producing fucosylated oligosaccharides - Google Patents

Fucosyltransferases and their use in producing fucosylated oligosaccharides

Info

Publication number
SG11202000015YA
SG11202000015YA SG11202000015YA SG11202000015YA SG11202000015YA SG 11202000015Y A SG11202000015Y A SG 11202000015YA SG 11202000015Y A SG11202000015Y A SG 11202000015YA SG 11202000015Y A SG11202000015Y A SG 11202000015YA SG 11202000015Y A SG11202000015Y A SG 11202000015YA
Authority
SG
Singapore
Prior art keywords
fucosyltransferases
fucosylated oligosaccharides
producing fucosylated
producing
oligosaccharides
Prior art date
Application number
SG11202000015YA
Other languages
English (en)
Inventor
Stefan Jennewein
Katja Parschat
Original Assignee
Jennewein Biotechnologie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jennewein Biotechnologie Gmbh filed Critical Jennewein Biotechnologie Gmbh
Publication of SG11202000015YA publication Critical patent/SG11202000015YA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/18Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21Addition of substantially indigestible substances, e.g. dietary fibres
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/01Hexosyltransferases (2.4.1)
    • C12Y204/010653-Galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase (2.4.1.65), i.e. alpha-1-3 fucosyltransferase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Pediatric Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
SG11202000015YA 2017-07-07 2018-07-06 Fucosyltransferases and their use in producing fucosylated oligosaccharides SG11202000015YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17180176.4A EP3425052A1 (en) 2017-07-07 2017-07-07 Fucosyltransferases and their use in producing fucosylated oligosaccharides
PCT/EP2018/068356 WO2019008133A1 (en) 2017-07-07 2018-07-06 FUCOSYLTRANSFERASES AND THEIR USE IN THE PRODUCTION OF FUCOSYLATED OLIGOSACCHARIDES

Publications (1)

Publication Number Publication Date
SG11202000015YA true SG11202000015YA (en) 2020-01-30

Family

ID=59350641

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202000015YA SG11202000015YA (en) 2017-07-07 2018-07-06 Fucosyltransferases and their use in producing fucosylated oligosaccharides

Country Status (11)

Country Link
US (1) US20200181665A1 (ja)
EP (2) EP3425052A1 (ja)
JP (2) JP2020526200A (ja)
KR (1) KR20200027496A (ja)
CN (1) CN110869508A (ja)
AU (1) AU2018296557B2 (ja)
BR (1) BR112020000164A2 (ja)
MX (1) MX2019015193A (ja)
PH (1) PH12020550007A1 (ja)
SG (1) SG11202000015YA (ja)
WO (1) WO2019008133A1 (ja)

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JP2022517903A (ja) * 2018-12-04 2022-03-11 グリコム・アクティーゼルスカブ フコシル化オリゴ糖の合成
EP3751003A1 (en) 2019-06-12 2020-12-16 Jennewein Biotechnologie GmbH Production of fucosylated oligosaccharides in bacillus
KR20220035247A (ko) * 2019-07-19 2022-03-21 인바이오스 엔.브이. 숙주 세포에서 푸코실락토스의 제조
EP3789495A1 (en) 2019-09-03 2021-03-10 Jennewein Biotechnologie GmbH Production of sialylated oligosaccharides in bacillus cells
CA3151145A1 (en) 2019-09-24 2021-04-01 David N. Cook Compositions and methods for treatment of inflammatory and immune diseases
CA3164948A1 (en) * 2019-12-17 2021-06-24 Inbiose N.V. Lactose converting alpha-1,2-fucosyltransferase enzymes
CN111534503B (zh) * 2020-05-09 2022-04-08 中国农业大学 Haloferula sp.β-N-乙酰氨基己糖苷酶在合成人乳寡糖中的应用
WO2021231744A1 (en) * 2020-05-13 2021-11-18 Brigham Young University Paper-based colorimetric covid-19/sars-cov-2 test
CN116249781A (zh) * 2020-08-10 2023-06-09 因比奥斯公司 在细胞中的含有GlcNAc的生物产品的产生
JP2023537608A (ja) 2020-08-14 2023-09-04 プロラクタ バイオサイエンス,インコーポレイテッド 細菌療法で使用するためのヒトミルクオリゴ糖組成物
CN111979168B (zh) * 2020-08-17 2022-07-22 江南大学 一种提高乳酰-n-三糖ii产量的基因工程菌及生产方法
CN112048447B (zh) * 2020-09-18 2022-03-08 杭州师范大学 一种重组胶红酵母及在生产水溶性中性多糖中的应用
CN112574936A (zh) * 2020-12-21 2021-03-30 中国科学院合肥物质科学研究院 一种重组大肠杆菌及其构建方法与应用
CA3204530A1 (en) 2021-01-12 2022-07-21 Gregory Mckenzie Synbiotic treatment regimens
WO2023182970A1 (en) * 2021-02-19 2023-09-28 The Regents Of The University Of California Methods for production of fucosylated oligosaccharides in recombinant cell culture
DK181242B1 (en) 2021-05-17 2023-05-30 Dsm Ip Assets Bv GENETICALLY ENGINEERED CELLS COMPRISING A RECOMBINANT NUCLEIC ACID SEQUNCE ENCODING AN α-1,2-FUCOSYLTRANSFERASE CAPABLE OF PRODUCING LNFP-I, NUCLEIC ACID SEQUENCES ENCODING SAME AND METHODS FOR USE OF SAME
WO2022243314A2 (en) 2021-05-17 2022-11-24 Dsm Ip Assets B.V. Methods of producing hmo blend profiles with lnfp-i and 2'-fl as the predominant compounds
CN116286919A (zh) * 2021-12-03 2023-06-23 虹摹生物科技(上海)有限公司 基因工程菌及利用其制备岩藻糖基化寡糖的方法
CN116286562A (zh) * 2021-12-10 2023-06-23 虹摹生物科技(上海)有限公司 一种基因工程菌及其制备方法和应用
WO2023110995A1 (en) * 2021-12-14 2023-06-22 Inbiose N.V. Production of alpha-1,3-fucosylated compounds
WO2023141513A2 (en) * 2022-01-19 2023-07-27 The Regents Of The University Of California Functionalized human milk oligosaccharides and methods for producing them
CN115927131A (zh) * 2022-04-28 2023-04-07 中国科学院青岛生物能源与过程研究所 可分泌和高产果糖的聚球藻yd03及其制备方法
DK202200588A1 (en) 2022-06-20 2024-02-23 Dsm Ip Assets Bv Mixture of fucosylated HMOs
CN115058465A (zh) * 2022-06-30 2022-09-16 山东大学 一种岩藻糖基化软骨素及其制备方法和应用
WO2024013348A1 (en) 2022-07-15 2024-01-18 Dsm Ip Assets B.V. New fucosyltransferases for in vivo synthesis of complex fucosylated human milk oligosaccharides
DK202200688A1 (en) 2022-07-15 2024-02-16 Dsm Ip Assets Bv New fucosyltransferase for in vivo synthesis of complex fucosylated human milk oligosaccharides
DK202200689A1 (en) 2022-07-15 2024-02-27 Dsm Ip Assets Bv New fucosyltransferases for in vivo synthesis of lnfp-iii
WO2024130119A2 (en) 2022-12-16 2024-06-20 Prolacta Bioscience, Inc. Synbiotic compositions for short chain fatty acid production
WO2024133701A1 (en) 2022-12-22 2024-06-27 Dsm Ip Assets B.V. New fucosyltransferases for in vivo synthesis of complex fucosylated human milk oligosaccharides mixtures comprising lndfh-iii
CN117187206B (zh) * 2023-05-19 2024-06-18 无锡特殊食品与营养健康研究院有限公司 肠道微生物来源的岩藻糖基转移酶及其应用

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
US6238894B1 (en) 1998-11-04 2001-05-29 Diane Taylor α1,2 fucosyltransferase
RU2517602C2 (ru) 2009-06-08 2014-05-27 Йенневайн Биотехнологи Гмбх Синтез нмо
EP2944690B1 (en) 2010-10-11 2017-12-20 Jennewein Biotechnologie GmbH Novel fucosyltransferases and their applications
EP2479263B1 (en) 2011-01-20 2013-11-27 Jennewein Biotechnologie GmbH Novel Fucosyltransferases and their applications
NL2007268C2 (en) * 2011-08-16 2013-02-19 Friesland Brands Bv Nutritional compositions comprising human milk oligosaccharides and uses thereof.
US9029136B2 (en) 2012-07-25 2015-05-12 Glycosyn LLC Alpha (1,2) fucosyltransferases suitable for use in the production of fucosylated oligosaccharides
EP3572521A1 (en) 2013-09-10 2019-11-27 Jennewein Biotechnologie GmbH Production of oligosaccharides
EP2927316B1 (en) 2014-03-31 2018-11-07 Jennewein Biotechnologie GmbH Total fermentation of oligosaccharides
CN106536726A (zh) * 2014-07-14 2017-03-22 巴斯夫欧洲公司 LNT、LNnT和其岩藻糖基化衍生物的生物技术生产
AU2015315110B2 (en) 2014-09-09 2021-04-08 Glycosyn LLC Alpha (1,3) fucosyltransferases for use in the production of fucosylated oligosaccharides
WO2017106864A1 (en) 2015-12-18 2017-06-22 The Regents Of The University Of California Te2ft enzyme for enzymatic synthesis of alpha1-2-fucosides

Also Published As

Publication number Publication date
PH12020550007A1 (en) 2020-10-12
JP2024028710A (ja) 2024-03-05
US20200181665A1 (en) 2020-06-11
JP2020526200A (ja) 2020-08-31
EP3425052A1 (en) 2019-01-09
KR20200027496A (ko) 2020-03-12
RU2020102747A3 (ja) 2022-04-14
CN110869508A (zh) 2020-03-06
WO2019008133A1 (en) 2019-01-10
AU2018296557B2 (en) 2024-05-23
AU2018296557A1 (en) 2020-01-16
EP3649248A1 (en) 2020-05-13
RU2020102747A (ru) 2021-08-09
MX2019015193A (es) 2020-02-07
BR112020000164A2 (pt) 2020-07-14

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