SG11202000015YA - Fucosyltransferases and their use in producing fucosylated oligosaccharides - Google Patents

Fucosyltransferases and their use in producing fucosylated oligosaccharides

Info

Publication number
SG11202000015YA
SG11202000015YA SG11202000015YA SG11202000015YA SG11202000015YA SG 11202000015Y A SG11202000015Y A SG 11202000015YA SG 11202000015Y A SG11202000015Y A SG 11202000015YA SG 11202000015Y A SG11202000015Y A SG 11202000015YA SG 11202000015Y A SG11202000015Y A SG 11202000015YA
Authority
SG
Singapore
Prior art keywords
fucosyltransferases
fucosylated oligosaccharides
producing fucosylated
producing
oligosaccharides
Prior art date
Application number
SG11202000015YA
Inventor
Stefan Jennewein
Katja Parschat
Original Assignee
Jennewein Biotechnologie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jennewein Biotechnologie Gmbh filed Critical Jennewein Biotechnologie Gmbh
Publication of SG11202000015YA publication Critical patent/SG11202000015YA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/18Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21Addition of substantially indigestible substances, e.g. dietary fibres
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/01Hexosyltransferases (2.4.1)
    • C12Y204/010653-Galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase (2.4.1.65), i.e. alpha-1-3 fucosyltransferase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pediatric Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
SG11202000015YA 2017-07-07 2018-07-06 Fucosyltransferases and their use in producing fucosylated oligosaccharides SG11202000015YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17180176.4A EP3425052A1 (en) 2017-07-07 2017-07-07 Fucosyltransferases and their use in producing fucosylated oligosaccharides
PCT/EP2018/068356 WO2019008133A1 (en) 2017-07-07 2018-07-06 Fucosyltransferases and their use in producing fucosylated oligosaccharides

Publications (1)

Publication Number Publication Date
SG11202000015YA true SG11202000015YA (en) 2020-01-30

Family

ID=59350641

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202000015YA SG11202000015YA (en) 2017-07-07 2018-07-06 Fucosyltransferases and their use in producing fucosylated oligosaccharides

Country Status (11)

Country Link
US (1) US20200181665A1 (en)
EP (2) EP3425052A1 (en)
JP (2) JP2020526200A (en)
KR (1) KR20200027496A (en)
CN (1) CN110869508A (en)
AU (1) AU2018296557B2 (en)
BR (1) BR112020000164A2 (en)
MX (1) MX2019015193A (en)
PH (1) PH12020550007A1 (en)
SG (1) SG11202000015YA (en)
WO (1) WO2019008133A1 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022517903A (en) * 2018-12-04 2022-03-11 グリコム・アクティーゼルスカブ Synthesis of fucosylated oligosaccharides
EP3751003A1 (en) 2019-06-12 2020-12-16 Jennewein Biotechnologie GmbH Production of fucosylated oligosaccharides in bacillus
US20220259631A1 (en) * 2019-07-19 2022-08-18 Inbiose N.V. Production of fucosyllactose in host cells
EP3789495A1 (en) 2019-09-03 2021-03-10 Jennewein Biotechnologie GmbH Production of sialylated oligosaccharides in bacillus cells
EP4034143A1 (en) 2019-09-24 2022-08-03 Prolacta Bioscience, Inc. Compositions and methods for treatment of inflammatory and immune diseases
EP4077648A1 (en) * 2019-12-17 2022-10-26 Inbiose N.V. Lactose converting alpha-1,2-fucosyltransferase enzymes
CN111534503B (en) * 2020-05-09 2022-04-08 中国农业大学 Application of Haloferrila sp
US20210355552A1 (en) * 2020-05-13 2021-11-18 Brigham Young University Paper-based colorimetric covid-19/sars-cov-2 test
US20230279403A1 (en) 2020-08-10 2023-09-07 Inbiose N.V. Production of alpha-1,3 glycosylated form of fuc-a1,2-gal-r
AU2021325955A1 (en) 2020-08-14 2023-03-02 Prolacta Bioscience, Inc. Human milk oligosaccharide compositions for use with bacteriotherapies
CN111979168B (en) * 2020-08-17 2022-07-22 江南大学 Genetic engineering bacterium for improving yield of lactoyl-N-trisaccharide II and production method
CN112048447B (en) * 2020-09-18 2022-03-08 杭州师范大学 Recombinant rhodotorula mucilaginosa and application thereof in production of water-soluble neutral polysaccharide
CN112574936A (en) * 2020-12-21 2021-03-30 中国科学院合肥物质科学研究院 Recombinant escherichia coli and construction method and application thereof
KR20230131228A (en) 2021-01-12 2023-09-12 프롤랙타 바이오사이언스, 인코포레이티드 Synbiotic treatment regimen
WO2023182970A1 (en) * 2021-02-19 2023-09-28 The Regents Of The University Of California Methods for production of fucosylated oligosaccharides in recombinant cell culture
WO2022243315A1 (en) 2021-05-17 2022-11-24 Dsm Ip Assets B.V. Methods of producing hmo blend profiles with lnfp-i and 2'-fl, with lnfp-i as the predominant compound
DK181242B1 (en) 2021-05-17 2023-05-30 Dsm Ip Assets Bv GENETICALLY ENGINEERED CELLS COMPRISING A RECOMBINANT NUCLEIC ACID SEQUNCE ENCODING AN α-1,2-FUCOSYLTRANSFERASE CAPABLE OF PRODUCING LNFP-I, NUCLEIC ACID SEQUENCES ENCODING SAME AND METHODS FOR USE OF SAME
CN116286919A (en) * 2021-12-03 2023-06-23 虹摹生物科技(上海)有限公司 Genetically engineered bacterium and method for preparing fucosylated oligosaccharides by using genetically engineered bacterium
CN116286562A (en) * 2021-12-10 2023-06-23 虹摹生物科技(上海)有限公司 Genetically engineered bacterium and preparation method and application thereof
WO2023110995A1 (en) * 2021-12-14 2023-06-22 Inbiose N.V. Production of alpha-1,3-fucosylated compounds
WO2023141513A2 (en) * 2022-01-19 2023-07-27 The Regents Of The University Of California Functionalized human milk oligosaccharides and methods for producing them
CN115927131A (en) * 2022-04-28 2023-04-07 中国科学院青岛生物能源与过程研究所 Synechococcus YD03 capable of secreting and producing fructose at high yield and preparation method thereof
DK202200588A1 (en) 2022-06-20 2024-02-23 Dsm Ip Assets Bv Mixture of fucosylated HMOs
CN115058465A (en) * 2022-06-30 2022-09-16 山东大学 Fucosylated chondroitin and preparation method and application thereof
WO2024013348A1 (en) 2022-07-15 2024-01-18 Dsm Ip Assets B.V. New fucosyltransferases for in vivo synthesis of complex fucosylated human milk oligosaccharides
DK202200689A1 (en) 2022-07-15 2024-02-27 Dsm Ip Assets Bv New fucosyltransferases for in vivo synthesis of lnfp-iii
DK202200688A1 (en) 2022-07-15 2024-02-16 Dsm Ip Assets Bv New fucosyltransferase for in vivo synthesis of complex fucosylated human milk oligosaccharides
CN117187206B (en) * 2023-05-19 2024-06-18 无锡特殊食品与营养健康研究院有限公司 Fucosyltransferase from intestinal microorganisms and application thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6238894B1 (en) 1998-11-04 2001-05-29 Diane Taylor α1,2 fucosyltransferase
RU2517602C2 (en) 2009-06-08 2014-05-27 Йенневайн Биотехнологи Гмбх Hmo synthesis
ES2663627T3 (en) 2010-10-11 2018-04-16 Jennewein Biotechnologie Gmbh Novel fucosyltransferases and their applications
ES2439507T3 (en) 2011-01-20 2014-01-23 Jennewein Biotechnologie Gmbh Novel fucosyltransferases and their applications
NL2007268C2 (en) * 2011-08-16 2013-02-19 Friesland Brands Bv Nutritional compositions comprising human milk oligosaccharides and uses thereof.
US9029136B2 (en) 2012-07-25 2015-05-12 Glycosyn LLC Alpha (1,2) fucosyltransferases suitable for use in the production of fucosylated oligosaccharides
ES2875327T3 (en) 2013-09-10 2021-11-10 Chr Hansen Hmo Gmbh Production of oligosaccharides
EP3461890A1 (en) 2014-03-31 2019-04-03 Jennewein Biotechnologie GmbH Total fermentation of oligosaccharides
KR20170028438A (en) * 2014-07-14 2017-03-13 바스프 에스이 Biotechnological production of lnt, lnnt and the fucosylated derivatives thereof
EP3191499A4 (en) 2014-09-09 2018-06-06 Glycosyn LLC Alpha (1,3) fucosyltransferases for use in the production of fucosylated oligosaccharides
US11572548B2 (en) 2015-12-18 2023-02-07 The Regents Of The University Of California Reaction mixture for synthesis of alpha1-2-fucosides

Also Published As

Publication number Publication date
US20200181665A1 (en) 2020-06-11
AU2018296557B2 (en) 2024-05-23
EP3425052A1 (en) 2019-01-09
CN110869508A (en) 2020-03-06
RU2020102747A3 (en) 2022-04-14
MX2019015193A (en) 2020-02-07
PH12020550007A1 (en) 2020-10-12
AU2018296557A1 (en) 2020-01-16
EP3649248A1 (en) 2020-05-13
RU2020102747A (en) 2021-08-09
JP2020526200A (en) 2020-08-31
KR20200027496A (en) 2020-03-12
WO2019008133A1 (en) 2019-01-10
BR112020000164A2 (en) 2020-07-14
JP2024028710A (en) 2024-03-05

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