SG11201912664WA - Nanoparticle, contrast agent for magnetic resonance imaging containing same, and ligand compound - Google Patents
Nanoparticle, contrast agent for magnetic resonance imaging containing same, and ligand compoundInfo
- Publication number
- SG11201912664WA SG11201912664WA SG11201912664WA SG11201912664WA SG11201912664WA SG 11201912664W A SG11201912664W A SG 11201912664WA SG 11201912664W A SG11201912664W A SG 11201912664WA SG 11201912664W A SG11201912664W A SG 11201912664WA SG 11201912664W A SG11201912664W A SG 11201912664WA
- Authority
- SG
- Singapore
- Prior art keywords
- nanoparticle
- magnetic resonance
- contrast agent
- resonance imaging
- containing same
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
- A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
- A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
- A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
- A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
- A61K49/1827—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
- A61K49/1833—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle having a (super)(para)magnetic core coated or functionalised with a small organic molecule
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
- C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nanotechnology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Radiology & Medical Imaging (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Composite Materials (AREA)
- Medical Informatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Materials Engineering (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017126755 | 2017-06-28 | ||
| PCT/JP2018/024416 WO2019004297A1 (ja) | 2017-06-28 | 2018-06-27 | ナノ粒子、これを含む磁気共鳴イメージング用造影剤及びリガンド化合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201912664WA true SG11201912664WA (en) | 2020-01-30 |
Family
ID=64742350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201912664WA SG11201912664WA (en) | 2017-06-28 | 2018-06-27 | Nanoparticle, contrast agent for magnetic resonance imaging containing same, and ligand compound |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US11389550B2 (ja) |
| EP (1) | EP3646888A4 (ja) |
| JP (1) | JP7107532B2 (ja) |
| KR (1) | KR20200018579A (ja) |
| CN (1) | CN110799219B (ja) |
| AU (1) | AU2018292927B2 (ja) |
| BR (1) | BR112019027478A2 (ja) |
| CA (1) | CA3068215A1 (ja) |
| CO (1) | CO2020000940A2 (ja) |
| IL (1) | IL271622A (ja) |
| JO (1) | JOP20190290A1 (ja) |
| MA (1) | MA49521A (ja) |
| MY (1) | MY201491A (ja) |
| PH (1) | PH12019502882A1 (ja) |
| RU (1) | RU2767430C2 (ja) |
| SG (1) | SG11201912664WA (ja) |
| UA (1) | UA125049C2 (ja) |
| WO (1) | WO2019004297A1 (ja) |
| ZA (1) | ZA202000265B (ja) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220089455A1 (en) * | 2018-12-27 | 2022-03-24 | Astellas Pharma Inc. | Method for producing nanoparticle having metal particle which contains iron oxide to which one or more hydrophilic ligands are coordination bonded |
| BR112021012694A2 (pt) * | 2018-12-27 | 2021-10-05 | Riken | Nanopartícula, agente de contraste para imagem de ressonância magnética compreendendo a mesma e composto de ligante zwitteriônico |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3123542A (en) | 1960-10-13 | 1964-03-03 | Electrolytic marking medium | |
| US8728529B2 (en) | 2008-12-29 | 2014-05-20 | General Electric Company | Nanoparticle contrast agents for diagnostic imaging |
| US8728440B2 (en) | 2012-08-23 | 2014-05-20 | General Electric Company | Nanoparticulate compositions for diagnostic imaging |
| US9399075B2 (en) | 2008-12-29 | 2016-07-26 | General Electric Company | Nanoparticle contrast agents for diagnostic imaging |
| ES2647567T3 (es) | 2008-12-29 | 2017-12-22 | General Electric Company | Agentes de contraste de nanopartículas para el diagnóstico por imágenes |
| US8574549B2 (en) | 2008-12-29 | 2013-11-05 | General Electric Company | Nanoparticle contrast agents for diagnostic imaging |
| US20100166664A1 (en) | 2008-12-29 | 2010-07-01 | General Electric Company | Nanoparticle contrast agents for diagnostic imaging |
| US9205155B2 (en) | 2009-10-30 | 2015-12-08 | General Electric Company | Treating water insoluble nanoparticles with hydrophilic alpha-hydroxyphosphonic acid conjugates, the so modified nanoparticles and their use as contrast agents |
| KR20130045647A (ko) * | 2011-10-26 | 2013-05-06 | 한국기초과학지원연구원 | 양쪽성 이온으로 코팅된 자기공명영상 조영제 |
| WO2013090601A2 (en) | 2011-12-16 | 2013-06-20 | Massachusetts Institute Of Technology | Compact nanoparticles for biological applications |
| US8821838B2 (en) | 2012-08-23 | 2014-09-02 | General Electric Company | Nanoparticulate compositions for diagnostic imaging |
| CN104740654B (zh) * | 2013-12-30 | 2017-12-29 | 中国科学院化学研究所 | 磁性纳米颗粒磁共振造影剂和增强磁性纳米颗粒弛豫率的方法 |
| HUE046306T2 (hu) * | 2014-01-07 | 2020-02-28 | Colorobbia Italiana Spa | Katekollal funkcionalizált mágneses nanorészecskék, elõállításuk és alkalmazásuk |
| JP6471227B2 (ja) | 2014-09-15 | 2019-02-13 | マサチューセッツ インスティテュート オブ テクノロジー | 磁気共鳴画像法用途のためのナノ粒子 |
| JP6577250B2 (ja) | 2015-06-02 | 2019-09-18 | 国立大学法人 東京大学 | 複合半透膜 |
| CN106390146A (zh) * | 2015-08-03 | 2017-02-15 | 天津大学 | 聚磺酸甜菜碱两性电解质修饰的磁性纳米粒子及其制备方法和应用 |
-
2018
- 2018-06-27 KR KR1020207000498A patent/KR20200018579A/ko not_active Application Discontinuation
- 2018-06-27 AU AU2018292927A patent/AU2018292927B2/en active Active
- 2018-06-27 US US16/624,946 patent/US11389550B2/en active Active
- 2018-06-27 SG SG11201912664WA patent/SG11201912664WA/en unknown
- 2018-06-27 MY MYPI2019007668A patent/MY201491A/en unknown
- 2018-06-27 MA MA049521A patent/MA49521A/fr unknown
- 2018-06-27 EP EP18823223.5A patent/EP3646888A4/en not_active Withdrawn
- 2018-06-27 WO PCT/JP2018/024416 patent/WO2019004297A1/ja unknown
- 2018-06-27 CN CN201880041378.2A patent/CN110799219B/zh active Active
- 2018-06-27 CA CA3068215A patent/CA3068215A1/en active Pending
- 2018-06-27 UA UAA202000282A patent/UA125049C2/uk unknown
- 2018-06-27 RU RU2019143780A patent/RU2767430C2/ru active
- 2018-06-27 JP JP2019526990A patent/JP7107532B2/ja active Active
- 2018-06-27 BR BR112019027478-2A patent/BR112019027478A2/pt unknown
- 2018-12-28 JO JOP/2019/0290A patent/JOP20190290A1/ar unknown
-
2019
- 2019-12-19 PH PH12019502882A patent/PH12019502882A1/en unknown
- 2019-12-19 IL IL271622A patent/IL271622A/en unknown
-
2020
- 2020-01-15 ZA ZA2020/00265A patent/ZA202000265B/en unknown
- 2020-01-27 CO CONC2020/0000940A patent/CO2020000940A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2019143780A3 (ja) | 2021-08-27 |
| IL271622A (en) | 2020-02-27 |
| UA125049C2 (uk) | 2021-12-29 |
| EP3646888A4 (en) | 2021-04-14 |
| JP7107532B2 (ja) | 2022-07-27 |
| MA49521A (fr) | 2020-05-06 |
| KR20200018579A (ko) | 2020-02-19 |
| CN110799219B (zh) | 2023-01-06 |
| AU2018292927A1 (en) | 2020-02-06 |
| RU2767430C2 (ru) | 2022-03-17 |
| JPWO2019004297A1 (ja) | 2020-04-30 |
| PH12019502882A1 (en) | 2020-10-26 |
| CA3068215A1 (en) | 2019-01-03 |
| US20200330617A1 (en) | 2020-10-22 |
| US11389550B2 (en) | 2022-07-19 |
| JOP20190290A1 (ar) | 2019-12-19 |
| AU2018292927B2 (en) | 2021-11-25 |
| ZA202000265B (en) | 2021-07-28 |
| BR112019027478A2 (pt) | 2020-07-07 |
| MY201491A (en) | 2024-02-27 |
| RU2019143780A (ru) | 2021-06-25 |
| CN110799219A (zh) | 2020-02-14 |
| CO2020000940A2 (es) | 2020-02-18 |
| EP3646888A1 (en) | 2020-05-06 |
| WO2019004297A1 (ja) | 2019-01-03 |
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