SG11201909516VA - Immunomodulating polynucleotides, antibody conjugates thereof, and methods of their use - Google Patents

Immunomodulating polynucleotides, antibody conjugates thereof, and methods of their use

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Publication number
SG11201909516VA
SG11201909516VA SG11201909516VA SG11201909516VA SG 11201909516V A SG11201909516V A SG 11201909516VA SG 11201909516V A SG11201909516V A SG 11201909516VA SG 11201909516V A SG11201909516V A SG 11201909516VA
Authority
SG
Singapore
Prior art keywords
california
san diego
international
immunomodulating
polynucleotides
Prior art date
Application number
Other languages
English (en)
Inventor
Sukumar Sakamuri
Curt W Bradshaw
Son Lam
Joseph Stock
Edward Hyungsuk Ha
Laxman Eltepu
Dingguo Liu
Bin Liu
Iacono Giuseppe Dello
Bryan R Meade
Ayman Kabakibi
Original Assignee
Tollnine Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tollnine Inc filed Critical Tollnine Inc
Publication of SG11201909516VA publication Critical patent/SG11201909516VA/en

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    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
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BR112019021520A2 (pt) 2020-08-04
US11203611B2 (en) 2021-12-21
US20220056069A1 (en) 2022-02-24
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