SG11201907762RA - Methods for multiplex detection of molecules - Google Patents
Methods for multiplex detection of moleculesInfo
- Publication number
- SG11201907762RA SG11201907762RA SG11201907762RA SG11201907762RA SG 11201907762R A SG11201907762R A SG 11201907762RA SG 11201907762R A SG11201907762R A SG 11201907762RA SG 11201907762R A SG11201907762R A SG 11201907762RA
- Authority
- SG
- Singapore
- Prior art keywords
- singapore
- international
- nucleic acid
- pct
- national
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/15—Modifications characterised by incorporating a consensus or conserved sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/186—Modifications characterised by incorporating a non-extendable or blocking moiety
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/10—Oligonucleotides as tagging agents for labelling antibodies
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SG10201702423X | 2017-03-24 | ||
| PCT/SG2018/050130 WO2018174827A1 (fr) | 2017-03-24 | 2018-03-23 | Procédés de détection multiplex de molécules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201907762RA true SG11201907762RA (en) | 2019-10-30 |
Family
ID=63586206
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201907762R SG11201907762RA (en) | 2017-03-24 | 2018-03-23 | Methods for multiplex detection of molecules |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230183791A1 (fr) |
| EP (1) | EP3601605B1 (fr) |
| JP (2) | JP2020513826A (fr) |
| KR (1) | KR20190133711A (fr) |
| CN (1) | CN110462058A (fr) |
| CA (1) | CA3054901A1 (fr) |
| SG (1) | SG11201907762RA (fr) |
| WO (1) | WO2018174827A1 (fr) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201405274WA (en) | 2012-02-27 | 2014-10-30 | Cellular Res Inc | Compositions and kits for molecular counting |
| US11591637B2 (en) | 2012-08-14 | 2023-02-28 | 10X Genomics, Inc. | Compositions and methods for sample processing |
| US10323279B2 (en) | 2012-08-14 | 2019-06-18 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10400280B2 (en) | 2012-08-14 | 2019-09-03 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10752949B2 (en) | 2012-08-14 | 2020-08-25 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US9701998B2 (en) | 2012-12-14 | 2017-07-11 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US9951386B2 (en) | 2014-06-26 | 2018-04-24 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US20150376609A1 (en) | 2014-06-26 | 2015-12-31 | 10X Genomics, Inc. | Methods of Analyzing Nucleic Acids from Individual Cells or Cell Populations |
| CA2894694C (fr) | 2012-12-14 | 2023-04-25 | 10X Genomics, Inc. | Procedes et systemes pour le traitement de polynucleotides |
| US10533221B2 (en) | 2012-12-14 | 2020-01-14 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| CA2900481A1 (fr) | 2013-02-08 | 2014-08-14 | 10X Genomics, Inc. | Generation de codes a barres de polynucleotides |
| SG10201806890VA (en) | 2013-08-28 | 2018-09-27 | Cellular Res Inc | Massively parallel single cell analysis |
| SG11201705615UA (en) | 2015-01-12 | 2017-08-30 | 10X Genomics Inc | Processes and systems for preparing nucleic acid sequencing libraries and libraries prepared using same |
| EP3262407B1 (fr) | 2015-02-24 | 2023-08-30 | 10X Genomics, Inc. | Procédés et systèmes de traitement de cloisonnement |
| US9727810B2 (en) | 2015-02-27 | 2017-08-08 | Cellular Research, Inc. | Spatially addressable molecular barcoding |
| EP3277843A2 (fr) | 2015-03-30 | 2018-02-07 | Cellular Research, Inc. | Procédés et compositions pour codage à barres combinatoire |
| CN107580632B (zh) | 2015-04-23 | 2021-12-28 | 贝克顿迪金森公司 | 用于全转录组扩增的方法和组合物 |
| WO2017044574A1 (fr) | 2015-09-11 | 2017-03-16 | Cellular Research, Inc. | Procédés et compositions pour la normalisation de banques d'acides nucléiques |
| US11371094B2 (en) | 2015-11-19 | 2022-06-28 | 10X Genomics, Inc. | Systems and methods for nucleic acid processing using degenerate nucleotides |
| US10301677B2 (en) | 2016-05-25 | 2019-05-28 | Cellular Research, Inc. | Normalization of nucleic acid libraries |
| US10202641B2 (en) | 2016-05-31 | 2019-02-12 | Cellular Research, Inc. | Error correction in amplification of samples |
| US10640763B2 (en) | 2016-05-31 | 2020-05-05 | Cellular Research, Inc. | Molecular indexing of internal sequences |
| WO2018058073A2 (fr) | 2016-09-26 | 2018-03-29 | Cellular Research, Inc. | Mesure d'expression de protéines à l'aide de réactifs avec des séquences d'oligonucléotides à code-barres |
| US10550429B2 (en) | 2016-12-22 | 2020-02-04 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| US10815525B2 (en) | 2016-12-22 | 2020-10-27 | 10X Genomics, Inc. | Methods and systems for processing polynucleotides |
| EP4029939B1 (fr) | 2017-01-30 | 2023-06-28 | 10X Genomics, Inc. | Procédés et systèmes de codage à barres de cellules individuelles sur la base de gouttelettes |
| CN110382708A (zh) | 2017-02-01 | 2019-10-25 | 赛卢拉研究公司 | 使用阻断性寡核苷酸进行选择性扩增 |
| US10995333B2 (en) | 2017-02-06 | 2021-05-04 | 10X Genomics, Inc. | Systems and methods for nucleic acid preparation |
| US10400235B2 (en) | 2017-05-26 | 2019-09-03 | 10X Genomics, Inc. | Single cell analysis of transposase accessible chromatin |
| CN116064732A (zh) | 2017-05-26 | 2023-05-05 | 10X基因组学有限公司 | 转座酶可接近性染色质的单细胞分析 |
| CA3059559A1 (fr) | 2017-06-05 | 2018-12-13 | Becton, Dickinson And Company | Indexation d'echantillon pour des cellules uniques |
| SG11201913654QA (en) | 2017-11-15 | 2020-01-30 | 10X Genomics Inc | Functionalized gel beads |
| US10829815B2 (en) | 2017-11-17 | 2020-11-10 | 10X Genomics, Inc. | Methods and systems for associating physical and genetic properties of biological particles |
| WO2019157529A1 (fr) | 2018-02-12 | 2019-08-15 | 10X Genomics, Inc. | Procédés de caractérisation d'analytes multiples à partir de cellules individuelles ou de populations cellulaires |
| SG11202009889VA (en) | 2018-04-06 | 2020-11-27 | 10X Genomics Inc | Systems and methods for quality control in single cell processing |
| JP7358388B2 (ja) | 2018-05-03 | 2023-10-10 | ベクトン・ディキンソン・アンド・カンパニー | 反対側の転写物末端における分子バーコーディング |
| US11773441B2 (en) | 2018-05-03 | 2023-10-03 | Becton, Dickinson And Company | High throughput multiomics sample analysis |
| US20200032335A1 (en) | 2018-07-27 | 2020-01-30 | 10X Genomics, Inc. | Systems and methods for metabolome analysis |
| US11639517B2 (en) | 2018-10-01 | 2023-05-02 | Becton, Dickinson And Company | Determining 5′ transcript sequences |
| AU2019364418A1 (en) | 2018-10-25 | 2021-04-22 | Illumina, Inc. | Methods and compositions for identifying ligands on arrays using indexes and barcodes |
| US11932849B2 (en) | 2018-11-08 | 2024-03-19 | Becton, Dickinson And Company | Whole transcriptome analysis of single cells using random priming |
| US11459607B1 (en) | 2018-12-10 | 2022-10-04 | 10X Genomics, Inc. | Systems and methods for processing-nucleic acid molecules from a single cell using sequential co-partitioning and composite barcodes |
| EP3894552A1 (fr) | 2018-12-13 | 2021-10-20 | Becton, Dickinson and Company | Extension sélective dans une analyse de transcriptome complet de cellule unique |
| US11845983B1 (en) | 2019-01-09 | 2023-12-19 | 10X Genomics, Inc. | Methods and systems for multiplexing of droplet based assays |
| EP3914728B1 (fr) | 2019-01-23 | 2023-04-05 | Becton, Dickinson and Company | Oligonucléotides associés à des anticorps |
| US11851683B1 (en) | 2019-02-12 | 2023-12-26 | 10X Genomics, Inc. | Methods and systems for selective analysis of cellular samples |
| CA3138806A1 (fr) * | 2019-05-22 | 2020-11-26 | Dalia Dhingra | Methode et appareil de sequencage cible simultane d'adn, d'arn et de proteine |
| US11939622B2 (en) | 2019-07-22 | 2024-03-26 | Becton, Dickinson And Company | Single cell chromatin immunoprecipitation sequencing assay |
| CN114729350A (zh) | 2019-11-08 | 2022-07-08 | 贝克顿迪金森公司 | 使用随机引发获得用于免疫组库测序的全长v(d)j信息 |
| WO2021146207A1 (fr) | 2020-01-13 | 2021-07-22 | Becton, Dickinson And Company | Procédés et compositions pour la quantification de protéines et d'arn |
| WO2021231779A1 (fr) | 2020-05-14 | 2021-11-18 | Becton, Dickinson And Company | Amorces pour profilage de répertoire immunitaire |
| US11932901B2 (en) | 2020-07-13 | 2024-03-19 | Becton, Dickinson And Company | Target enrichment using nucleic acid probes for scRNAseq |
| CN116635533A (zh) | 2020-11-20 | 2023-08-22 | 贝克顿迪金森公司 | 高表达的蛋白和低表达的蛋白的谱分析 |
| CN113702641A (zh) * | 2021-08-25 | 2021-11-26 | 上海交通大学 | 一锅式核酸-抗体共检测方法及应用 |
| WO2024017263A1 (fr) * | 2022-07-18 | 2024-01-25 | Genans Biotechnology Co., Ltd | Composition de détection et son utilisation |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9917816D0 (en) * | 1999-07-29 | 1999-09-29 | Cytocell Ltd | Chemically modified probes used to regulate nucleic acid amplification assays |
| EP1451365A4 (fr) * | 2001-11-13 | 2006-09-13 | Rubicon Genomics Inc | Amplification et sequencage d'adn au moyen de molecules d'adn produite par fragmentation aleatoire |
| US10385392B2 (en) | 2011-12-30 | 2019-08-20 | Abbott Molecular Inc. | Nucleic acid hybridization probes |
| US9528107B2 (en) * | 2012-01-31 | 2016-12-27 | Pacific Biosciences Of California, Inc. | Compositions and methods for selection of nucleic acids |
| NO2694769T3 (fr) * | 2012-03-06 | 2018-03-03 | ||
| SG10201806890VA (en) * | 2013-08-28 | 2018-09-27 | Cellular Res Inc | Massively parallel single cell analysis |
| WO2016011364A1 (fr) * | 2014-07-18 | 2016-01-21 | Cdi Laboratories, Inc. | Procédés et compositions pour identifier, quantifier, et caractériser des analytes cibles et des fragments de liaison |
| US11639522B2 (en) * | 2015-01-30 | 2023-05-02 | President And Fellows Of Harvard College | Microscope-free imaging |
| US11873483B2 (en) * | 2015-03-11 | 2024-01-16 | The Broad Institute, Inc. | Proteomic analysis with nucleic acid identifiers |
| WO2016145416A2 (fr) * | 2015-03-11 | 2016-09-15 | The Broad Institute, Inc. | Analyse protéomique avec des identificateurs d'acide nucléique |
| WO2018057051A1 (fr) | 2016-09-24 | 2018-03-29 | Abvitro Llc | Conjugés affinité-oligonucléotide et leurs utilisations |
| US11156611B2 (en) * | 2015-09-24 | 2021-10-26 | Abvitro Llc | Single cell characterization using affinity-oligonucleotide conjugates and vessel barcoded polynucleotides |
| US20190144936A1 (en) * | 2016-01-15 | 2019-05-16 | Massachusetts Institute Of Technology | Semi-permeable arrays for analyzing biological systems and methods of using same |
-
2018
- 2018-03-23 KR KR1020197031059A patent/KR20190133711A/ko not_active Application Discontinuation
- 2018-03-23 US US16/495,744 patent/US20230183791A1/en active Pending
- 2018-03-23 JP JP2019552052A patent/JP2020513826A/ja active Pending
- 2018-03-23 WO PCT/SG2018/050130 patent/WO2018174827A1/fr active Application Filing
- 2018-03-23 EP EP18770338.4A patent/EP3601605B1/fr active Active
- 2018-03-23 CN CN201880020053.6A patent/CN110462058A/zh active Pending
- 2018-03-23 SG SG11201907762R patent/SG11201907762RA/en unknown
- 2018-03-23 CA CA3054901A patent/CA3054901A1/fr active Pending
-
2023
- 2023-01-12 JP JP2023003321A patent/JP2023040233A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN110462058A (zh) | 2019-11-15 |
| US20230183791A1 (en) | 2023-06-15 |
| KR20190133711A (ko) | 2019-12-03 |
| EP3601605B1 (fr) | 2023-11-22 |
| EP3601605C0 (fr) | 2023-11-22 |
| WO2018174827A1 (fr) | 2018-09-27 |
| EP3601605A1 (fr) | 2020-02-05 |
| JP2020513826A (ja) | 2020-05-21 |
| EP3601605A4 (fr) | 2021-01-06 |
| JP2023040233A (ja) | 2023-03-22 |
| CA3054901A1 (fr) | 2018-09-27 |
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