SG11201906804UA - Zwitterionically modified polymers and hydrogels - Google Patents

Zwitterionically modified polymers and hydrogels

Info

Publication number
SG11201906804UA
SG11201906804UA SG11201906804UA SG11201906804UA SG11201906804UA SG 11201906804U A SG11201906804U A SG 11201906804UA SG 11201906804U A SG11201906804U A SG 11201906804UA SG 11201906804U A SG11201906804U A SG 11201906804UA SG 11201906804U A SG11201906804U A SG 11201906804UA
Authority
SG
Singapore
Prior art keywords
international
cornell university
ithaca
pct
present
Prior art date
Application number
SG11201906804UA
Other languages
English (en)
Inventor
Minglin Ma
Qingsheng Liu
Original Assignee
Univ Cornell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Cornell filed Critical Univ Cornell
Publication of SG11201906804UA publication Critical patent/SG11201906804UA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0084—Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F116/00—Homopolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical
    • C08F116/02—Homopolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical by an alcohol radical
    • C08F116/04—Acyclic compounds
    • C08F116/06—Polyvinyl alcohol ; Vinyl alcohol
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F16/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical
    • C08F16/02—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical by an alcohol radical
    • C08F16/04—Acyclic compounds
    • C08F16/06—Polyvinyl alcohol ; Vinyl alcohol
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L29/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers
    • C08L29/02—Homopolymers or copolymers of unsaturated alcohols
    • C08L29/04—Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/04—Alginic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Materials Engineering (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Saccharide Compounds (AREA)
SG11201906804UA 2017-01-27 2018-01-27 Zwitterionically modified polymers and hydrogels SG11201906804UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762451629P 2017-01-27 2017-01-27
PCT/US2018/015613 WO2018140834A1 (fr) 2017-01-27 2018-01-27 Polymères et hydrogels modifiés de manière zwitterionique

Publications (1)

Publication Number Publication Date
SG11201906804UA true SG11201906804UA (en) 2019-08-27

Family

ID=62978825

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201906804UA SG11201906804UA (en) 2017-01-27 2018-01-27 Zwitterionically modified polymers and hydrogels

Country Status (13)

Country Link
US (2) US11634512B2 (fr)
EP (1) EP3573624A4 (fr)
JP (1) JP7198210B2 (fr)
KR (1) KR102618302B1 (fr)
CN (2) CN110381956B (fr)
AU (1) AU2018212895B2 (fr)
BR (1) BR112019015141A2 (fr)
CA (1) CA3051142A1 (fr)
IL (1) IL267991A (fr)
MX (1) MX2019008388A (fr)
RU (1) RU2019126801A (fr)
SG (1) SG11201906804UA (fr)
WO (1) WO2018140834A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220127421A1 (en) * 2019-03-05 2022-04-28 University Of Florida Research Foundation, Inc. Polyurethane copolymers and blends, methods of manufacture thereof and articles containing the same
KR102413336B1 (ko) * 2020-07-10 2022-06-27 부경대학교 산학협력단 다공성 알지네이트 기반 하이드로겔, 이의 제조방법 및 이를 이용한 약물 전달체
CN113563267B (zh) * 2021-07-08 2023-05-30 深圳华源再生医学有限公司 一种磺酸甜菜碱的制备方法及应用
CN113667141B (zh) * 2021-07-09 2023-10-03 深圳华源再生医学有限公司 抗蛋白粘附的海藻酸盐水凝胶及其制备方法和应用
CN114702606A (zh) * 2022-02-18 2022-07-05 深圳华源再生医学有限公司 一种两性离子修饰的多糖类聚合物及其制备方法与应用
WO2023230524A1 (fr) 2022-05-25 2023-11-30 Flagship Pioneering Innovations Vi, Llc Compositions de cellules sécrétoires et/ou catalytiques et procédés les utilisant
WO2023235884A1 (fr) 2022-06-03 2023-12-07 Flagship Pioneering Innovations Vi, Llc Compositions et méthodes

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US2744130A (en) 1952-04-11 1956-05-01 Du Pont Quaternary ammonium monomers and polymers thereof
US4868121A (en) 1985-02-07 1989-09-19 Mcdonnell Douglas Corporation Islet isolation process
US5821121A (en) 1991-06-24 1998-10-13 Pacific Biomedical Research, Inc. Hormone-secreting cells maintained in long-term culture
JPH05148288A (ja) 1991-11-29 1993-06-15 Kao Corp 新規ベタイン化糖化合物
US5273904A (en) 1992-03-18 1993-12-28 Cobe Laboratories, Inc. Apparatus for purifying islets of Langerhans
JP4335316B2 (ja) 1996-09-19 2009-09-30 ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・ミシガン アルギネートまたは修飾アルギネートのようなポリサッカライドを含むポリマー
CA2297025A1 (fr) 1997-07-25 1999-02-04 Sdg, Inc. Compositions pharmaceutiques a base de polymeres destinees a une administration ciblee d'agents biologiquement actifs
GB0119665D0 (en) * 2001-08-10 2001-10-03 Isis Innovation Conjugates
AU2003210959A1 (en) 2002-02-12 2003-09-04 Cornell Research Foundation, Inc. Identification and high-yield isolation of human pancreatic islet progenitor and stem cells
US20090105238A1 (en) 2005-10-17 2009-04-23 Isagro Ricerca S.R.L Compounds and Relative use for the Control of Phytopathogens
JP6067376B2 (ja) * 2009-11-06 2017-01-25 ユニヴァーシティ・オブ・ワシントン・スルー・イッツ・センター・フォー・コマーシャリゼーション 架橋した双性イオンヒドロゲル
US9085757B2 (en) 2010-06-17 2015-07-21 Regents Of The University Of Minnesota Production of insulin producing cells
JP5690671B2 (ja) 2010-06-30 2015-03-25 富士フイルム株式会社 新規な重合性組成物及びそれに用いる重合性化合物、並びに新規な重合性組成物を用いた画像形成材料及び平版印刷版原版
WO2012167223A1 (fr) * 2011-06-02 2012-12-06 Massachusetts Institute Of Technology Alginates modifiés pour l'encapsulation cellulaire et la thérapie cellulaire
CZ303879B6 (cs) 2012-02-28 2013-06-05 Contipro Biotech S.R.O. Deriváty na bázi kyseliny hyaluronové schopné tvorit hydrogely, zpusob jejich prípravy, hydrogely na bázi techto derivátu, zpusob jejich prípravy a pouzití
WO2014194268A1 (fr) 2013-05-30 2014-12-04 The University Of Akron Hydrogels à base de carboxybétaïne permutables antimicrobiens et antisalissures
US20160251470A1 (en) * 2013-10-14 2016-09-01 The University Of Akron Zwitterionic polysaccharide polymers having antifouling, antimicrobial and optical transparency properties
US10426735B2 (en) 2014-08-01 2019-10-01 Massachusetts Institute Of Technology Modified alginates for anti-fibrotic materials and applications
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US20190185867A1 (en) 2016-06-16 2019-06-20 Pioneer Hi-Bred International, Inc. Compositions and methods to control insect pests

Also Published As

Publication number Publication date
MX2019008388A (es) 2019-12-02
EP3573624A4 (fr) 2020-10-21
KR20190109446A (ko) 2019-09-25
CN110381956B (zh) 2024-02-02
RU2019126801A3 (fr) 2021-05-24
US20190389979A1 (en) 2019-12-26
AU2018212895A1 (en) 2019-08-15
CN118108677A (zh) 2024-05-31
CA3051142A1 (fr) 2018-08-02
IL267991A (en) 2019-09-26
KR102618302B1 (ko) 2023-12-28
WO2018140834A1 (fr) 2018-08-02
RU2019126801A (ru) 2021-03-02
BR112019015141A2 (pt) 2020-03-24
AU2018212895B2 (en) 2024-02-22
US20240018276A1 (en) 2024-01-18
CN110381956A (zh) 2019-10-25
EP3573624A1 (fr) 2019-12-04
JP7198210B2 (ja) 2022-12-28
JP2020506919A (ja) 2020-03-05
US11634512B2 (en) 2023-04-25

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