SG11201903750RA - Improved sensing for automated biological cell injection - Google Patents

Improved sensing for automated biological cell injection

Info

Publication number
SG11201903750RA
SG11201903750RA SG11201903750RA SG11201903750RA SG11201903750RA SG 11201903750R A SG11201903750R A SG 11201903750RA SG 11201903750R A SG11201903750R A SG 11201903750RA SG 11201903750R A SG11201903750R A SG 11201903750RA SG 11201903750R A SG11201903750R A SG 11201903750RA
Authority
SG
Singapore
Prior art keywords
needle
cell
stage
international
tower
Prior art date
Application number
SG11201903750RA
Other languages
English (en)
Inventor
Arunava Steven Banerjee
Original Assignee
Mekonos Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2016904438A external-priority patent/AU2016904438A0/en
Application filed by Mekonos Ltd filed Critical Mekonos Ltd
Publication of SG11201903750RA publication Critical patent/SG11201903750RA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/04Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
    • C12M33/06Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles for multiple inoculation or multiple collection of samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B25HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
    • B25JMANIPULATORS; CHAMBERS PROVIDED WITH MANIPULATION DEVICES
    • B25J7/00Micromanipulators
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B81MICROSTRUCTURAL TECHNOLOGY
    • B81BMICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B3/00Devices comprising flexible or deformable elements, e.g. comprising elastic tongues or membranes
    • B81B3/0062Devices moving in two or more dimensions, i.e. having special features which allow movement in more than one dimension
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B81MICROSTRUCTURAL TECHNOLOGY
    • B81BMICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2201/00Specific applications of microelectromechanical systems
    • B81B2201/03Microengines and actuators
    • B81B2201/033Comb drives
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B81MICROSTRUCTURAL TECHNOLOGY
    • B81BMICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2201/00Specific applications of microelectromechanical systems
    • B81B2201/05Microfluidics
    • B81B2201/055Microneedles
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • C12M1/12Apparatus for enzymology or microbiology with sterilisation, filtration or dialysis means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • C12M1/26Inoculator or sampler
    • C12M1/32Inoculator or sampler multiple field or continuous type
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N23/00Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00
    • GPHYSICS
    • G21NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21KTECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
    • G21K7/00Gamma- or X-ray microscopes
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01LSEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
    • H01L21/00Processes or apparatus adapted for the manufacture or treatment of semiconductor or solid state devices or of parts thereof
    • H01L21/02Manufacture or treatment of semiconductor devices or of parts thereof
    • H01L21/04Manufacture or treatment of semiconductor devices or of parts thereof the devices having potential barriers, e.g. a PN junction, depletion layer or carrier concentration layer
    • H01L21/18Manufacture or treatment of semiconductor devices or of parts thereof the devices having potential barriers, e.g. a PN junction, depletion layer or carrier concentration layer the devices having semiconductor bodies comprising elements of Group IV of the Periodic Table or AIIIBV compounds with or without impurities, e.g. doping materials
    • H01L21/30Treatment of semiconductor bodies using processes or apparatus not provided for in groups H01L21/20 - H01L21/26
    • H01L21/302Treatment of semiconductor bodies using processes or apparatus not provided for in groups H01L21/20 - H01L21/26 to change their surface-physical characteristics or shape, e.g. etching, polishing, cutting
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01LSEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
    • H01L23/00Details of semiconductor or other solid state devices
    • H01L23/58Structural electrical arrangements for semiconductor devices not otherwise provided for, e.g. in combination with batteries

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Robotics (AREA)
  • Mechanical Engineering (AREA)
  • Molecular Biology (AREA)
  • Computer Hardware Design (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Clinical Laboratory Science (AREA)
  • Microscoopes, Condenser (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Fluid Mechanics (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
SG11201903750RA 2016-10-31 2017-10-31 Improved sensing for automated biological cell injection SG11201903750RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2016904438A AU2016904438A0 (en) 2016-10-31 Improved Sensing for Automated Biological Cell Injection
PCT/NZ2017/050141 WO2018080325A1 (fr) 2016-10-31 2017-10-31 Détection améliorée pour injection automatisée dans des cellules biologiques

Publications (1)

Publication Number Publication Date
SG11201903750RA true SG11201903750RA (en) 2019-05-30

Family

ID=62023823

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201903750RA SG11201903750RA (en) 2016-10-31 2017-10-31 Improved sensing for automated biological cell injection

Country Status (8)

Country Link
US (2) US11567096B2 (fr)
EP (1) EP3532623A4 (fr)
KR (3) KR20240134062A (fr)
CN (1) CN110100002B (fr)
AU (1) AU2017349495B2 (fr)
CA (1) CA3041779A1 (fr)
SG (1) SG11201903750RA (fr)
WO (1) WO2018080325A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201903797SA (en) * 2016-10-31 2019-05-30 Mekonos Ltd An array of needle manipulators for biological cell injection
JP7404396B2 (ja) * 2019-04-23 2023-12-25 メコノス,インコーポレイテッド インターフェイスのためのキャビティに近接した粒子の誘電泳動固定化
AU2020290475B2 (en) 2019-06-13 2023-08-24 Mekonos Inc. Micro-electro-mechanical-system structures and applications thereof

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262128A (en) 1989-10-23 1993-11-16 The United States Of America As Represented By The Department Of Health And Human Services Array-type multiple cell injector
GB9615775D0 (en) * 1996-07-26 1996-09-04 British Tech Group Apparatus and method for characterising particles using dielectrophoresis
US6645757B1 (en) * 2001-02-08 2003-11-11 Sandia Corporation Apparatus and method for transforming living cells
US6686299B2 (en) * 2001-06-21 2004-02-03 Carlo D. Montemagno Nanosyringe array and method
US20070087436A1 (en) * 2003-04-11 2007-04-19 Atsushi Miyawaki Microinjection method and device
JP2004344036A (ja) * 2003-05-21 2004-12-09 Fujitsu Ltd 物質導入装置及び物質導入システム
US7557470B2 (en) * 2005-01-18 2009-07-07 Massachusetts Institute Of Technology 6-axis electromagnetically-actuated meso-scale nanopositioner
US7306471B2 (en) 2005-07-22 2007-12-11 Chow Shau-Din Universal power plug with adjustable rotating bodies
US20070194225A1 (en) * 2005-10-07 2007-08-23 Zorn Miguel D Coherent electron junction scanning probe interference microscope, nanomanipulator and spectrometer with assembler and DNA sequencing applications
CA2560352A1 (fr) 2006-09-21 2008-03-21 Yu Sun Systeme et methode d'injection automatique a haut rendement de cellules
JP5086620B2 (ja) * 2006-11-30 2012-11-28 オリンパス株式会社 遺伝子導入装置及び方法
WO2010079580A1 (fr) 2009-01-09 2010-07-15 Ntn株式会社 Appareil de micro-injection et procédé de micro-injection
CN103025886A (zh) * 2010-05-25 2013-04-03 阿尔利克斯公司 用于确定颗粒和/或细胞分散体的迁移率的全息波动显微装置和方法
EP2541300A4 (fr) * 2010-08-06 2018-04-18 NSK Ltd. Système manipulateur et procédé de manipulation d'objets microscopiques à manipuler
KR101951968B1 (ko) * 2011-03-03 2019-02-25 더 리전트 오브 더 유니버시티 오브 캘리포니아 세포 조작용 나노피펫 장치
US9931478B2 (en) * 2011-04-10 2018-04-03 David Hirshberg Needles system
EP2535151B1 (fr) * 2011-06-17 2018-03-28 Eppendorf Ag Appareil d'actionneur avec dispositif de commande
US8855476B2 (en) * 2011-09-28 2014-10-07 DigitalOptics Corporation MEMS MEMS-based optical image stabilization
US20130102078A1 (en) * 2011-10-21 2013-04-25 Nanoinjection Technologies, L.L.C. Nanoinjection system dna placement pipette coupler
WO2013126556A1 (fr) 2012-02-21 2013-08-29 Indiana University Research And Technology Corporation Dispositif de micro-injection à ultra-haut débit
GB2508906A (en) * 2012-12-14 2014-06-18 Life Science Methods Bv Frame element for sample injection with optical control means
CN107636475A (zh) * 2015-02-26 2018-01-26 沙朗特有限责任公司 用于制造纳电子机械系统探针的系统和方法
CN105441325B (zh) * 2015-10-20 2017-12-19 河海大学常州校区 可调节细胞姿态的显微注射芯片、控制装置及工作方法
SG11201903797SA (en) * 2016-10-31 2019-05-30 Mekonos Ltd An array of needle manipulators for biological cell injection

Also Published As

Publication number Publication date
EP3532623A1 (fr) 2019-09-04
WO2018080325A9 (fr) 2019-05-09
US11567096B2 (en) 2023-01-31
CA3041779A1 (fr) 2018-05-03
US20230144463A1 (en) 2023-05-11
EP3532623A4 (fr) 2020-07-01
KR20220159487A (ko) 2022-12-02
KR102470240B1 (ko) 2022-11-23
US20200150141A1 (en) 2020-05-14
AU2017349495B2 (en) 2023-09-07
AU2017349495A1 (en) 2019-06-06
WO2018080325A1 (fr) 2018-05-03
CN110100002A (zh) 2019-08-06
KR102701901B1 (ko) 2024-08-30
CN110100002B (zh) 2023-08-18
KR20190070988A (ko) 2019-06-21
KR20240134062A (ko) 2024-09-05

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