SG11201908075UA - A microneedle device - Google Patents

A microneedle device

Info

Publication number
SG11201908075UA
SG11201908075UA SG11201908075UA SG11201908075UA SG11201908075UA SG 11201908075U A SG11201908075U A SG 11201908075UA SG 11201908075U A SG11201908075U A SG 11201908075UA SG 11201908075U A SG11201908075U A SG 11201908075UA SG 11201908075U A SG11201908075U A SG 11201908075UA
Authority
SG
Singapore
Prior art keywords
singapore
international
microneedle device
national university
faculty
Prior art date
Application number
SG11201908075UA
Inventor
Lifeng Kang
Yuanyuan Sun
Duc-Viet Nguyen
Original Assignee
Nat Univ Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Univ Singapore filed Critical Nat Univ Singapore
Publication of SG11201908075UA publication Critical patent/SG11201908075UA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241Containing particulates characterized by their shape and/or structure
    • A61K8/0245Specific shapes or structures not provided for by any of the groups of A61K8/0241
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241Containing particulates characterized by their shape and/or structure
    • A61K8/025Explicitly spheroidal or spherical shape
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • A61K9/4825Proteins, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/003Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor characterised by the choice of material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046Solid microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053Methods for producing microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061Methods for using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0244Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/27General characteristics of the apparatus preventing use
    • A61M2205/273General characteristics of the apparatus preventing use preventing reuse, e.g. of disposables
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29KINDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2089/00Use of proteins, e.g. casein, gelatine or derivatives thereof, as moulding material

Abstract

b) (d) () INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 07 September 2018 (07.09.2018) W I PO I PCT onion °nolo omioollm olomoilowo oimIE (10) International Publication Number WO 2018/160140 Al (51) International Patent Classification: A61M 37/00 (2006.01) (21) International Application Number: PCT/SG2018/050096 (22) International Filing Date: 01 March 2018 (01.03.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 10201701636U 01 March 2017 (01.03.2017) SG (71) Applicant: NATIONAL UNIVERSITY OF SINGA- PORE [SG/SG]; 21 Lower Kent Ridge Road, Singapore 119077 (SG). (72) Inventors: KANG, Lifeng; c/o National University of Sin- gapore, Faculty of Science / Department of Pharmacy, 21 Lower Kent Ridge Road, Singapore 119077 (SG). SUN, Yuanyuan; c/o National University of Singapore, Faculty of Science / Department of Pharmacy, 21 Lower Kent Ridge Road, Singapore 119077 (SG). NGUYEN, Due-Viet; c/o National University of Singapore, Faculty of Science / De- partment of Pharmacy, 21 Lower Kent Ridge Road, Singa- pore 119077 (SG). (74) Agent: PATEL, Upasana; Marks & Clerk Singapore LLP, Tanjong Pagar, P 0 Box 636, Singapore 910816 (SG). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: — of inventorship (Rule 4.17(iv)) Published: with international search report (Art. 21(3)) = (54) Title: A MICRONEEDLE DEVICE Figure 2 1-1 (57) : There is provided a microneedle device comprising a substrate and a plurality of microneedles projecting from the \" substrate, the substrate being substantially spherical and wherein in use, the microneedle device has three-dimensional movement. There 0 is also provided a method of forming the microneedle device of the present invention.
SG11201908075UA 2017-03-01 2018-03-01 A microneedle device SG11201908075UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SG10201701636U 2017-03-01
PCT/SG2018/050096 WO2018160140A1 (en) 2017-03-01 2018-03-01 A microneedle device

Publications (1)

Publication Number Publication Date
SG11201908075UA true SG11201908075UA (en) 2019-09-27

Family

ID=63369542

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201912501SA SG10201912501SA (en) 2017-03-01 2018-03-01 A microneedle device
SG11201908075UA SG11201908075UA (en) 2017-03-01 2018-03-01 A microneedle device

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201912501SA SG10201912501SA (en) 2017-03-01 2018-03-01 A microneedle device

Country Status (6)

Country Link
US (1) US11801371B2 (en)
JP (2) JP2020510480A (en)
KR (1) KR20190121843A (en)
CN (2) CN110582321A (en)
SG (2) SG10201912501SA (en)
WO (1) WO2018160140A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
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CA3055022A1 (en) * 2016-03-01 2017-09-08 Georgia Tech Research Corporation Microneedle particles, compositions, and methods of treatment and delivering a substance of interest
EP3873494A4 (en) 2018-10-31 2021-12-29 The Regents of the University of California Biodegradable microneedles for transdermal therapeutic agent delivery
CN111136841B (en) * 2019-12-16 2022-08-09 深圳市中科先见医疗科技有限公司 Preparation method of hydrogel microneedle mould and hydrogel microneedle mould
WO2021142160A1 (en) * 2020-01-10 2021-07-15 The Regents Of The University Of California Gelatin-based microneedle patch for minimally-invasive extraction of bodily fluids
WO2022098314A1 (en) * 2020-11-09 2022-05-12 National University Of Singapore A multi-layered sheet mask
CN112426514B (en) * 2020-11-26 2023-02-28 南京鼓楼医院 Stomach target oral macromolecular carrier and preparation method thereof
CN112675124A (en) * 2020-12-29 2021-04-20 浙江摩达生物科技有限公司 Preparation method of modified autolytic hyaluronic acid microneedle and application of modified autolytic hyaluronic acid microneedle in field of drug rehabilitation medicines
CN113018209A (en) * 2021-03-08 2021-06-25 广东粤港澳大湾区国家纳米科技创新研究院 Mask containing sea urchin type microneedle particles
WO2023009073A2 (en) * 2021-07-30 2023-02-02 Nusmetics Pte. Ltd. A microneedle apparatus
CN115227957A (en) * 2022-07-26 2022-10-25 空芯微医疗科技(上海)有限责任公司 Method for preparing hollow microneedle and product thereof

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US6197013B1 (en) * 1996-11-06 2001-03-06 Setagon, Inc. Method and apparatus for drug and gene delivery
WO2002064196A1 (en) 2001-02-14 2002-08-22 Novo Nordisk A/S Electronically controlled injection or infusion device
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GB201210718D0 (en) * 2012-06-18 2012-08-01 Studden Christopher J Micro needlle bead finger held solution administrator pad
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CN113908424A (en) 2014-04-24 2022-01-11 佐治亚科技研究公司 Microneedle and method for producing same
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CN105797266A (en) * 2016-03-07 2016-07-27 李媚 Micro-structure body and preparation method thereof

Also Published As

Publication number Publication date
US20200121900A1 (en) 2020-04-23
SG10201912501SA (en) 2020-02-27
KR20190121843A (en) 2019-10-28
WO2018160140A1 (en) 2018-09-07
CN110582321A (en) 2019-12-17
CN116617551A (en) 2023-08-22
JP2020510480A (en) 2020-04-09
US11801371B2 (en) 2023-10-31
JP2023027150A (en) 2023-03-01

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