SG11201901834WA - Micrornas as biomarkers for endometriosis - Google Patents
Micrornas as biomarkers for endometriosisInfo
- Publication number
- SG11201901834WA SG11201901834WA SG11201901834WA SG11201901834WA SG11201901834WA SG 11201901834W A SG11201901834W A SG 11201901834WA SG 11201901834W A SG11201901834W A SG 11201901834WA SG 11201901834W A SG11201901834W A SG 11201901834WA SG 11201901834W A SG11201901834W A SG 11201901834WA
- Authority
- SG
- Singapore
- Prior art keywords
- mir
- international
- pct
- endometriosis
- english
- Prior art date
Links
- 201000009273 Endometriosis Diseases 0.000 title abstract 3
- 108091070501 miRNA Proteins 0.000 title abstract 3
- 239000000090 biomarker Substances 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 108091027766 Mir-143 Proteins 0.000 abstract 1
- 108091028684 Mir-145 Proteins 0.000 abstract 1
- 238000012512 characterization method Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 108091090860 miR-150 stem-loop Proteins 0.000 abstract 1
- 108091041042 miR-18 stem-loop Proteins 0.000 abstract 1
- 108091062221 miR-18a stem-loop Proteins 0.000 abstract 1
- 108091065175 miR-3613 stem-loop Proteins 0.000 abstract 1
- 108091032770 miR-451 stem-loop Proteins 0.000 abstract 1
- 108091030646 miR-451a stem-loop Proteins 0.000 abstract 1
- 108091040808 miR-675 stem-loop Proteins 0.000 abstract 1
- 239000002679 microRNA Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/364—Endometriosis, i.e. non-malignant disorder in which functioning endometrial tissue is present outside the uterine cavity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Reproductive Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Pregnancy & Childbirth (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Engineering & Computer Science (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662381130P | 2016-08-30 | 2016-08-30 | |
| PCT/US2017/049284 WO2018044979A1 (en) | 2016-08-30 | 2017-08-30 | Micrornas as biomarkers for endometriosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201901834WA true SG11201901834WA (en) | 2019-03-28 |
Family
ID=61301726
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201901834WA SG11201901834WA (en) | 2016-08-30 | 2017-08-30 | Micrornas as biomarkers for endometriosis |
| SG10202102509TA SG10202102509TA (en) | 2016-08-30 | 2017-08-30 | Micrornas as biomarkers for endometriosis |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202102509TA SG10202102509TA (en) | 2016-08-30 | 2017-08-30 | Micrornas as biomarkers for endometriosis |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US10982282B2 (https=) |
| EP (1) | EP3506912B1 (https=) |
| JP (2) | JP2019528081A (https=) |
| KR (1) | KR20190057305A (https=) |
| CN (1) | CN109890394A (https=) |
| AU (1) | AU2017319325A1 (https=) |
| BR (1) | BR112019004075A2 (https=) |
| CA (1) | CA3035429A1 (https=) |
| MX (1) | MX2019002425A (https=) |
| SG (2) | SG11201901834WA (https=) |
| WO (1) | WO2018044979A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3800267A1 (en) | 2014-03-27 | 2021-04-07 | Yale University | Circulating micrornas as biomarkers for endometriosis |
| MX2019002425A (es) | 2016-08-30 | 2019-08-16 | Univ Yale | Micro ácidos ribonucleicos como biomarcadores para la endometriosis. |
| WO2019046494A1 (en) * | 2017-08-30 | 2019-03-07 | Dot Laboratories, Inc. | METHODS AND COMPOSITIONS FOR DETECTION AND TREATMENT OF ENDOMETRIOSIS |
| US12286629B2 (en) | 2018-07-13 | 2025-04-29 | Yale University | Compositions and methods for treating endometriosis |
| KR102089559B1 (ko) | 2018-08-31 | 2020-03-16 | 차의과학대학교 산학협력단 | 난소의 fsh에 대한 반응성의 진단 또는 예측용 바이오마커 및 이의 용도 |
| WO2020092672A2 (en) * | 2018-10-31 | 2020-05-07 | Yale University | A quantitative algorithm for endometriosis |
| US11315660B2 (en) | 2018-10-31 | 2022-04-26 | Dot Laboratories, Inc. | Method of detecting and treating endometriosis in a female subject |
| WO2020146544A1 (en) * | 2019-01-09 | 2020-07-16 | Research Institute At Nationwide Children's Hospital | A novel method for monitoring endometriosis and associated disorders |
| WO2020179895A1 (ja) | 2019-03-07 | 2020-09-10 | 東レ株式会社 | 子宮平滑筋肉腫の検出のためのキット、デバイス及び方法 |
| ES2787725A1 (es) * | 2019-04-15 | 2020-10-16 | Univ Granada | Metodo de obtencion de datos utiles para diagnosticar telangiectasia hemorragica hereditaria |
| CN110144394A (zh) * | 2019-04-18 | 2019-08-20 | 辽宁省肿瘤医院 | 一种子宫内膜异位症诊断、预后标志物及其应用 |
| EP4004551A1 (en) * | 2019-07-22 | 2022-06-01 | F. Hoffmann-La Roche AG | Substance p as blood biomarker for the non-invasive diagnosis of endometriosis |
| WO2021013785A1 (en) * | 2019-07-22 | 2021-01-28 | F. Hoffmann-La Roche Ag | S100a9 as blood biomarker for the non-invasive diagnosis of endometriosis |
| EP4004553A1 (en) * | 2019-07-22 | 2022-06-01 | F. Hoffmann-La Roche AG | S100a8 as blood biomarker for the non-invasive diagnosis of endometriosis |
| US11965879B2 (en) | 2019-08-23 | 2024-04-23 | Mcmaster University | Method for diagnosing and assessing endometriosis |
| KR102242639B1 (ko) * | 2020-01-28 | 2021-04-21 | 고려대학교 산학협력단 | 간 섬유화 진단용 바이오마커 miRNA4668-5p |
| KR102316507B1 (ko) * | 2020-02-28 | 2021-10-22 | 차의과학대학교 산학협력단 | 난소 예비력 바이오마커 및 이의 용도 |
| CN111909997B (zh) * | 2020-09-09 | 2021-09-28 | 上海交通大学 | miRNA标志物在制备奥氮平治疗精神分裂症疗效评估方面的产品中的应用及试剂盒 |
| JP2022063860A (ja) * | 2020-10-12 | 2022-04-22 | 学校法人近畿大学 | ホウ素化合物およびその製造方法 |
| KR102940037B1 (ko) * | 2022-12-06 | 2026-03-16 | 연세대학교 산학협력단 | 자궁내막증 진단용 조성물 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090317820A1 (en) | 2008-05-19 | 2009-12-24 | The Regents Of The University Of California | Micro-rna profile in human saliva and its use for detection of oral cancer |
| WO2010056337A2 (en) | 2008-11-12 | 2010-05-20 | Caris Mpi, Inc. | Methods and systems of using exosomes for determining phenotypes |
| CA2757517A1 (en) | 2009-04-07 | 2010-10-21 | Velin-Pharma A/S | Method and device for treatment of conditions associated with inflammation or undesirable activation of the immune system |
| EP2542696B1 (en) * | 2010-03-01 | 2016-09-28 | Caris Life Sciences Switzerland Holdings GmbH | Biomarkers for theranostics |
| CA2825522A1 (en) * | 2011-01-26 | 2012-08-02 | Cepheid | Methods of detecting lung cancer |
| US20140024590A1 (en) * | 2011-02-18 | 2014-01-23 | Yale University | KRAS-Variant And Endometriosis |
| FR2984358A1 (fr) | 2011-12-16 | 2013-06-21 | Genethon | Methodes pour le diagnostic de dystrophies musculaires |
| WO2013148151A1 (en) | 2012-03-29 | 2013-10-03 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Plasma microribonucleic acids as biomarkers for endometriosis and endometriosis-associated ovarian cancer |
| US10927412B2 (en) | 2013-10-01 | 2021-02-23 | The Regents Of The University Of California | Endometriosis classifier |
| CN105917005B (zh) * | 2013-11-18 | 2020-09-11 | 迪阿米尔有限责任公司 | 使用来自体液的miRNA检测和监控帕金森病(PD)的方法 |
| GB201403489D0 (en) | 2014-02-27 | 2014-04-16 | Univ London Queen Mary | Biomarkers for endometriosis |
| US9650676B2 (en) | 2014-03-19 | 2017-05-16 | University Of South Carolina | Leukocyte MicroRNAS for use in diagnosis and treatment of endometriosis |
| EP3800267A1 (en) | 2014-03-27 | 2021-04-07 | Yale University | Circulating micrornas as biomarkers for endometriosis |
| EP2924126B1 (en) * | 2014-03-28 | 2018-04-18 | Tervisetehnoloogiate Arenduskeskus AS | Method for using microRNA (miRNA) for detection of endometriosis |
| GB201603967D0 (en) * | 2016-03-08 | 2016-04-20 | Univ Birmingham | Biomarkers of traumatic brain injury |
| MX2019002425A (es) | 2016-08-30 | 2019-08-16 | Univ Yale | Micro ácidos ribonucleicos como biomarcadores para la endometriosis. |
| WO2019046494A1 (en) | 2017-08-30 | 2019-03-07 | Dot Laboratories, Inc. | METHODS AND COMPOSITIONS FOR DETECTION AND TREATMENT OF ENDOMETRIOSIS |
| US11315660B2 (en) | 2018-10-31 | 2022-04-26 | Dot Laboratories, Inc. | Method of detecting and treating endometriosis in a female subject |
| WO2020092672A2 (en) | 2018-10-31 | 2020-05-07 | Yale University | A quantitative algorithm for endometriosis |
| BR112021021866A2 (pt) | 2019-04-29 | 2021-12-21 | Dot Laboraties Inc | Classificadores para a detecção de endometriose |
-
2017
- 2017-08-30 MX MX2019002425A patent/MX2019002425A/es unknown
- 2017-08-30 CA CA3035429A patent/CA3035429A1/en active Pending
- 2017-08-30 JP JP2019511953A patent/JP2019528081A/ja active Pending
- 2017-08-30 AU AU2017319325A patent/AU2017319325A1/en not_active Abandoned
- 2017-08-30 BR BR112019004075-7A patent/BR112019004075A2/pt not_active Application Discontinuation
- 2017-08-30 EP EP17847431.8A patent/EP3506912B1/en active Active
- 2017-08-30 KR KR1020197009115A patent/KR20190057305A/ko not_active Ceased
- 2017-08-30 WO PCT/US2017/049284 patent/WO2018044979A1/en not_active Ceased
- 2017-08-30 SG SG11201901834WA patent/SG11201901834WA/en unknown
- 2017-08-30 US US16/329,436 patent/US10982282B2/en active Active
- 2017-08-30 CN CN201780066779.9A patent/CN109890394A/zh active Pending
- 2017-08-30 SG SG10202102509TA patent/SG10202102509TA/en unknown
-
2021
- 2021-02-25 US US17/184,894 patent/US11220713B2/en active Active
- 2021-11-02 US US17/517,014 patent/US12077803B2/en active Active
-
2022
- 2022-09-16 JP JP2022147738A patent/JP2022188086A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3506912B1 (en) | 2024-04-03 |
| CN109890394A (zh) | 2019-06-14 |
| US20190276893A1 (en) | 2019-09-12 |
| US11220713B2 (en) | 2022-01-11 |
| US20220049312A1 (en) | 2022-02-17 |
| MX2019002425A (es) | 2019-08-16 |
| JP2022188086A (ja) | 2022-12-20 |
| KR20190057305A (ko) | 2019-05-28 |
| JP2019528081A (ja) | 2019-10-10 |
| US12077803B2 (en) | 2024-09-03 |
| SG10202102509TA (en) | 2021-04-29 |
| WO2018044979A1 (en) | 2018-03-08 |
| BR112019004075A2 (pt) | 2019-05-28 |
| AU2017319325A1 (en) | 2019-03-21 |
| EP3506912A1 (en) | 2019-07-10 |
| US10982282B2 (en) | 2021-04-20 |
| EP3506912A4 (en) | 2020-08-19 |
| US20210180134A1 (en) | 2021-06-17 |
| CA3035429A1 (en) | 2018-03-08 |
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