CA3035429A1 - Micrornas as biomarkers for endometriosis - Google Patents
Micrornas as biomarkers for endometriosis Download PDFInfo
- Publication number
- CA3035429A1 CA3035429A1 CA3035429A CA3035429A CA3035429A1 CA 3035429 A1 CA3035429 A1 CA 3035429A1 CA 3035429 A CA3035429 A CA 3035429A CA 3035429 A CA3035429 A CA 3035429A CA 3035429 A1 CA3035429 A1 CA 3035429A1
- Authority
- CA
- Canada
- Prior art keywords
- mir
- mirna
- endometriosis
- subject
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/364—Endometriosis, i.e. non-malignant disorder in which functioning endometrial tissue is present outside the uterine cavity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Reproductive Health (AREA)
- Biophysics (AREA)
- Pregnancy & Childbirth (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Engineering & Computer Science (AREA)
- Gynecology & Obstetrics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662381130P | 2016-08-30 | 2016-08-30 | |
| US62/381,130 | 2016-08-30 | ||
| PCT/US2017/049284 WO2018044979A1 (en) | 2016-08-30 | 2017-08-30 | Micrornas as biomarkers for endometriosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3035429A1 true CA3035429A1 (en) | 2018-03-08 |
Family
ID=61301726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3035429A Pending CA3035429A1 (en) | 2016-08-30 | 2017-08-30 | Micrornas as biomarkers for endometriosis |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US10982282B2 (https=) |
| EP (1) | EP3506912B1 (https=) |
| JP (2) | JP2019528081A (https=) |
| KR (1) | KR20190057305A (https=) |
| CN (1) | CN109890394A (https=) |
| AU (1) | AU2017319325A1 (https=) |
| BR (1) | BR112019004075A2 (https=) |
| CA (1) | CA3035429A1 (https=) |
| MX (1) | MX2019002425A (https=) |
| SG (2) | SG10202102509TA (https=) |
| WO (1) | WO2018044979A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3873487A4 (en) * | 2018-10-31 | 2022-08-03 | Yale University | QUANTITATIVE ALGORITHM FOR ENDOMETRIOSIS |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3122905B1 (en) | 2014-03-27 | 2020-09-09 | Yale University | Circulating micrornas as biomarkers for endometriosis |
| WO2018044979A1 (en) | 2016-08-30 | 2018-03-08 | Yale University | Micrornas as biomarkers for endometriosis |
| AU2018324040A1 (en) * | 2017-08-30 | 2020-03-05 | Dot Laboratories, Inc. | Methods and compositions for detecting and treating endometriosis |
| EP3820483A4 (en) * | 2018-07-13 | 2023-03-01 | Yale University | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ENDOMETRIOSIS |
| KR102089559B1 (ko) | 2018-08-31 | 2020-03-16 | 차의과학대학교 산학협력단 | 난소의 fsh에 대한 반응성의 진단 또는 예측용 바이오마커 및 이의 용도 |
| US11315660B2 (en) | 2018-10-31 | 2022-04-26 | Dot Laboratories, Inc. | Method of detecting and treating endometriosis in a female subject |
| WO2020146544A1 (en) * | 2019-01-09 | 2020-07-16 | Research Institute At Nationwide Children's Hospital | A novel method for monitoring endometriosis and associated disorders |
| JPWO2020179895A1 (https=) | 2019-03-07 | 2020-09-10 | ||
| ES2787725A1 (es) * | 2019-04-15 | 2020-10-16 | Univ Granada | Metodo de obtencion de datos utiles para diagnosticar telangiectasia hemorragica hereditaria |
| CN110144394A (zh) * | 2019-04-18 | 2019-08-20 | 辽宁省肿瘤医院 | 一种子宫内膜异位症诊断、预后标志物及其应用 |
| WO2021013785A1 (en) * | 2019-07-22 | 2021-01-28 | F. Hoffmann-La Roche Ag | S100a9 as blood biomarker for the non-invasive diagnosis of endometriosis |
| WO2021013784A1 (en) * | 2019-07-22 | 2021-01-28 | F. Hoffmann-La Roche Ag | S100a8 as blood biomarker for the non-invasive diagnosis of endometriosis |
| JP7315780B2 (ja) * | 2019-07-22 | 2023-07-26 | エフ． ホフマン－ラ ロシュ アーゲー | 子宮内膜症の非侵襲的診断のための血液バイオマーカーとしてのサブスタンスｐ |
| US11965879B2 (en) | 2019-08-23 | 2024-04-23 | Mcmaster University | Method for diagnosing and assessing endometriosis |
| KR102242639B1 (ko) * | 2020-01-28 | 2021-04-21 | 고려대학교 산학협력단 | 간 섬유화 진단용 바이오마커 miRNA4668-5p |
| KR102316507B1 (ko) * | 2020-02-28 | 2021-10-22 | 차의과학대학교 산학협력단 | 난소 예비력 바이오마커 및 이의 용도 |
| CN111909997B (zh) * | 2020-09-09 | 2021-09-28 | 上海交通大学 | miRNA标志物在制备奥氮平治疗精神分裂症疗效评估方面的产品中的应用及试剂盒 |
| JP2022063860A (ja) * | 2020-10-12 | 2022-04-22 | 学校法人近畿大学 | ホウ素化合物およびその製造方法 |
| KR102940037B1 (ko) * | 2022-12-06 | 2026-03-16 | 연세대학교 산학협력단 | 자궁내막증 진단용 조성물 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009143181A2 (en) | 2008-05-19 | 2009-11-26 | The Regents Of The University Of California | Micro-rna profile in human saliva and its use for detection of oral cancer |
| WO2011109440A1 (en) * | 2010-03-01 | 2011-09-09 | Caris Life Sciences Luxembourg Holdings | Biomarkers for theranostics |
| GB2463401B (en) | 2008-11-12 | 2014-01-29 | Caris Life Sciences Luxembourg Holdings S A R L | Characterizing prostate disorders by analysis of microvesicles |
| DK2416789T3 (en) | 2009-04-07 | 2017-10-09 | Velin-Pharma As | Method and apparatus for treating diseases associated with inflammation or unwanted activation of the immune system |
| JP2014513521A (ja) * | 2011-01-26 | 2014-06-05 | セファイド | 肺癌を検出する方法 |
| EP2675914A1 (en) | 2011-02-18 | 2013-12-25 | Yale University, Inc. | The kras-variant and endometriosis |
| FR2984358A1 (fr) | 2011-12-16 | 2013-06-21 | Genethon | Methodes pour le diagnostic de dystrophies musculaires |
| WO2013148151A1 (en) | 2012-03-29 | 2013-10-03 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Plasma microribonucleic acids as biomarkers for endometriosis and endometriosis-associated ovarian cancer |
| WO2015050875A1 (en) | 2013-10-01 | 2015-04-09 | The Regents Of The University Of California | Endometriosis classifier |
| JP6930832B2 (ja) * | 2013-11-18 | 2021-09-01 | ディアミール, エルエルシーDiamir, Llc | パーキンソン病（ＰＤ）の検出およびモニタリングのための、体液からのｍｉＲＮＡを使用する方法 |
| GB201403489D0 (en) | 2014-02-27 | 2014-04-16 | Univ London Queen Mary | Biomarkers for endometriosis |
| US9650676B2 (en) | 2014-03-19 | 2017-05-16 | University Of South Carolina | Leukocyte MicroRNAS for use in diagnosis and treatment of endometriosis |
| EP3122905B1 (en) * | 2014-03-27 | 2020-09-09 | Yale University | Circulating micrornas as biomarkers for endometriosis |
| EP2924126B1 (en) * | 2014-03-28 | 2018-04-18 | Tervisetehnoloogiate Arenduskeskus AS | Method for using microRNA (miRNA) for detection of endometriosis |
| GB201603967D0 (en) * | 2016-03-08 | 2016-04-20 | Univ Birmingham | Biomarkers of traumatic brain injury |
| WO2018044979A1 (en) | 2016-08-30 | 2018-03-08 | Yale University | Micrornas as biomarkers for endometriosis |
| AU2018324040A1 (en) | 2017-08-30 | 2020-03-05 | Dot Laboratories, Inc. | Methods and compositions for detecting and treating endometriosis |
| CA3118133A1 (en) | 2018-10-31 | 2020-05-07 | Yale University | A quantitative algorithm for endometriosis |
| US11315660B2 (en) | 2018-10-31 | 2022-04-26 | Dot Laboratories, Inc. | Method of detecting and treating endometriosis in a female subject |
| WO2020223238A1 (en) | 2019-04-29 | 2020-11-05 | Yale University | Classifiers for detection of endometriosis |
-
2017
- 2017-08-30 WO PCT/US2017/049284 patent/WO2018044979A1/en not_active Ceased
- 2017-08-30 AU AU2017319325A patent/AU2017319325A1/en not_active Abandoned
- 2017-08-30 SG SG10202102509TA patent/SG10202102509TA/en unknown
- 2017-08-30 EP EP17847431.8A patent/EP3506912B1/en active Active
- 2017-08-30 SG SG11201901834WA patent/SG11201901834WA/en unknown
- 2017-08-30 US US16/329,436 patent/US10982282B2/en active Active
- 2017-08-30 KR KR1020197009115A patent/KR20190057305A/ko not_active Ceased
- 2017-08-30 CN CN201780066779.9A patent/CN109890394A/zh active Pending
- 2017-08-30 CA CA3035429A patent/CA3035429A1/en active Pending
- 2017-08-30 MX MX2019002425A patent/MX2019002425A/es unknown
- 2017-08-30 JP JP2019511953A patent/JP2019528081A/ja active Pending
- 2017-08-30 BR BR112019004075-7A patent/BR112019004075A2/pt not_active Application Discontinuation
-
2021
- 2021-02-25 US US17/184,894 patent/US11220713B2/en active Active
- 2021-11-02 US US17/517,014 patent/US12077803B2/en active Active
-
2022
- 2022-09-16 JP JP2022147738A patent/JP2022188086A/ja active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3873487A4 (en) * | 2018-10-31 | 2022-08-03 | Yale University | QUANTITATIVE ALGORITHM FOR ENDOMETRIOSIS |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3506912B1 (en) | 2024-04-03 |
| US12077803B2 (en) | 2024-09-03 |
| SG11201901834WA (en) | 2019-03-28 |
| SG10202102509TA (en) | 2021-04-29 |
| JP2019528081A (ja) | 2019-10-10 |
| WO2018044979A1 (en) | 2018-03-08 |
| US20220049312A1 (en) | 2022-02-17 |
| MX2019002425A (es) | 2019-08-16 |
| CN109890394A (zh) | 2019-06-14 |
| US11220713B2 (en) | 2022-01-11 |
| EP3506912A1 (en) | 2019-07-10 |
| US20210180134A1 (en) | 2021-06-17 |
| JP2022188086A (ja) | 2022-12-20 |
| AU2017319325A1 (en) | 2019-03-21 |
| KR20190057305A (ko) | 2019-05-28 |
| BR112019004075A2 (pt) | 2019-05-28 |
| EP3506912A4 (en) | 2020-08-19 |
| US10982282B2 (en) | 2021-04-20 |
| US20190276893A1 (en) | 2019-09-12 |
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Legal Events
| Date | Code | Title | Description |
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| EEER | Examination request |
Effective date: 20220823 |
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| MFA | Maintenance fee for application paid |
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| U11 | Full renewal or maintenance fee paid |
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Free format text: ST27 STATUS EVENT CODE: N-2-6-B10-B12-B303 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: DEEMED ABANDONED - FAILURE TO RESPOND TO AN EXAMINER'S REQUISITION Effective date: 20250407 |
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| MFA | Maintenance fee for application paid |
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| U00 | Fee paid |
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| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20250822 |