SG11201901783UA - A device to manipulate ions of same or different polarities - Google Patents

A device to manipulate ions of same or different polarities

Info

Publication number
SG11201901783UA
SG11201901783UA SG11201901783UA SG11201901783UA SG11201901783UA SG 11201901783U A SG11201901783U A SG 11201901783UA SG 11201901783U A SG11201901783U A SG 11201901783UA SG 11201901783U A SG11201901783U A SG 11201901783UA SG 11201901783U A SG11201901783U A SG 11201901783UA
Authority
SG
Singapore
Prior art keywords
international
electrodes
pair
opposing electrode
ions
Prior art date
Application number
SG11201901783UA
Other languages
English (en)
Inventor
Yehia Ibrahim
Richard Smith
Original Assignee
Battelle Memorial Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Battelle Memorial Institute filed Critical Battelle Memorial Institute
Publication of SG11201901783UA publication Critical patent/SG11201901783UA/en

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0095—Particular arrangements for generating, introducing or analyzing both positive and negative analyte ions
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/062—Ion guides
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/062—Ion guides
    • H01J49/063—Multipole ion guides, e.g. quadrupoles, hexapoles
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/06—Electron- or ion-optical arrangements
    • H01J49/062—Ion guides
    • H01J49/065—Ion guides having stacked electrodes, e.g. ring stack, plate stack
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/422—Two-dimensional RF ion traps
    • H01J49/4235—Stacked rings or stacked plates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Electron Tubes For Measurement (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
SG11201901783UA 2016-09-08 2017-06-28 A device to manipulate ions of same or different polarities SG11201901783UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15/260,046 US10224194B2 (en) 2016-09-08 2016-09-08 Device to manipulate ions of same or different polarities
PCT/US2017/039770 WO2018048494A1 (en) 2016-09-08 2017-06-28 A device to manipulate ions of same or different polarities

Publications (1)

Publication Number Publication Date
SG11201901783UA true SG11201901783UA (en) 2019-03-28

Family

ID=59337888

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201901783UA SG11201901783UA (en) 2016-09-08 2017-06-28 A device to manipulate ions of same or different polarities

Country Status (6)

Country Link
US (2) US10224194B2 (https=)
EP (1) EP3510626A1 (https=)
JP (1) JP6905587B2 (https=)
CA (1) CA3035818C (https=)
SG (1) SG11201901783UA (https=)
WO (1) WO2018048494A1 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10317364B2 (en) 2015-10-07 2019-06-11 Battelle Memorial Institute Method and apparatus for ion mobility separations utilizing alternating current waveforms
US10224194B2 (en) * 2016-09-08 2019-03-05 Battelle Memorial Institute Device to manipulate ions of same or different polarities
GB2579314A (en) * 2017-08-16 2020-06-17 Battelle Memorial Institute Methods and systems for ion manipulation
US10692710B2 (en) * 2017-08-16 2020-06-23 Battelle Memorial Institute Frequency modulated radio frequency electric field for ion manipulation
EP3692564A1 (en) 2017-10-04 2020-08-12 Battelle Memorial Institute Methods and systems for integrating ion manipulation devices
US10332723B1 (en) 2017-12-20 2019-06-25 Battelle Memorial Institute Ion focusing device
US11219393B2 (en) 2018-07-12 2022-01-11 Trace Matters Scientific Llc Mass spectrometry system and method for analyzing biological samples
US10720315B2 (en) 2018-06-05 2020-07-21 Trace Matters Scientific Llc Reconfigurable sequentially-packed ion (SPION) transfer device
US10840077B2 (en) 2018-06-05 2020-11-17 Trace Matters Scientific Llc Reconfigureable sequentially-packed ion (SPION) transfer device
US12089932B2 (en) 2018-06-05 2024-09-17 Trace Matters Scientific Llc Apparatus, system, and method for transferring ions
US10460920B1 (en) 2018-06-26 2019-10-29 Battelle Memorial Institute Flexible ion conduit
WO2020237037A1 (en) 2019-05-21 2020-11-26 MOBILion Systems, Inc. Voltage control for ion mobility separation
US11119069B2 (en) 2019-05-28 2021-09-14 Battelle Memorial Institute Device and method to manipulate ions in multi level system
GB2586787A (en) * 2019-08-30 2021-03-10 Shimadzu Corp Device for performing field asymmetric waveform ion mobility spectrometry
GB2586786A (en) * 2019-08-30 2021-03-10 Shimadzu Corp Device for performing field asymmetric waveform ion mobility spectrometry
WO2021102406A1 (en) 2019-11-22 2021-05-27 MOBILion Systems, Inc. Mobility based filtering of ions
US12163920B2 (en) 2020-04-06 2024-12-10 MOBILion Systems, Inc. Systems and methods for two-dimensional mobility based filtering of ions
US11662333B2 (en) 2020-04-06 2023-05-30 MOBILion Systems, Inc. Systems and methods for two-dimensional mobility based filtering of ions
US12354835B2 (en) * 2020-05-07 2025-07-08 Battelle Memorial Institute Systems and methods for selective molecular ion deposition
CN115885176A (zh) 2020-05-22 2023-03-31 莫比莱昂系统有限公司 用于俘获和积累离子的方法和装置
WO2021247820A1 (en) 2020-06-05 2021-12-09 MOBILion Systems, Inc. Apparatus and methods for ion manipulation having improved duty cycle
WO2022147201A1 (en) 2020-12-31 2022-07-07 Mobliion Systems, Inc. Systems and methods for extracting ions from a gas flow
US12327651B2 (en) * 2021-08-19 2025-06-10 Quantinuum Llc Periodic multi-dimensional atomic object confinement apparatus having curved legs
CN116153759B (zh) * 2023-02-15 2026-03-27 西安电子科技大学 一种横向堆叠结构的无门化离子迁移管

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19523859C2 (de) 1995-06-30 2000-04-27 Bruker Daltonik Gmbh Vorrichtung für die Reflektion geladener Teilchen
GB9519033D0 (en) 1995-09-18 1995-11-15 Smithkline Beecham Plc Treatment
MXPA02001588A (es) 1999-08-16 2002-07-02 Univ Johns Hopkins Reflectron de iones, que comprende unt ablero flexible de circuito impreso.
US6593570B2 (en) * 2000-05-24 2003-07-15 Agilent Technologies, Inc. Ion optic components for mass spectrometers
CA2391140C (en) 2001-06-25 2008-10-07 Micromass Limited Mass spectrometer
US7095013B2 (en) 2002-05-30 2006-08-22 Micromass Uk Limited Mass spectrometer
US20040195503A1 (en) 2003-04-04 2004-10-07 Taeman Kim Ion guide for mass spectrometers
GB0514964D0 (en) * 2005-07-21 2005-08-24 Ms Horizons Ltd Mass spectrometer devices & methods of performing mass spectrometry
GB0403533D0 (en) 2004-02-18 2004-03-24 Hoffman Andrew Mass spectrometer
US7365317B2 (en) 2004-05-21 2008-04-29 Analytica Of Branford, Inc. RF surfaces and RF ion guides
DE102004048496B4 (de) 2004-10-05 2008-04-30 Bruker Daltonik Gmbh Ionenführung mit HF-Blendenstapeln
GB0426520D0 (en) * 2004-12-02 2005-01-05 Micromass Ltd Mass spectrometer
GB0427634D0 (en) 2004-12-17 2005-01-19 Micromass Ltd Mass spectrometer
EP1956635B1 (en) 2005-11-28 2013-05-15 Hitachi, Ltd. Ion guide device, ion reactor, and mass analyzer
US7548818B2 (en) 2005-12-07 2009-06-16 Mds Analytical Technologies Automated analysis of complex matrices using mass spectrometer
CN101416271B (zh) * 2006-05-22 2010-07-14 株式会社岛津制作所 平行板电极布置设备和方法
GB2451239B (en) * 2007-07-23 2009-07-08 Microsaic Systems Ltd Microengineered electrode assembly
GB0718468D0 (en) 2007-09-21 2007-10-31 Micromass Ltd Mass spectrometer
GB0723183D0 (en) * 2007-11-23 2008-01-09 Micromass Ltd Mass spectrometer
US7888635B2 (en) 2008-05-30 2011-02-15 Battelle Memorial Institute Ion funnel ion trap and process
CN102150219B (zh) 2008-07-28 2015-01-28 莱克公司 在射频场中使用网的离子操纵的方法和设备
US7838826B1 (en) 2008-08-07 2010-11-23 Bruker Daltonics, Inc. Apparatus and method for parallel flow ion mobility spectrometry combined with mass spectrometry
US8309911B2 (en) * 2009-08-25 2012-11-13 Agilent Technologies, Inc. Methods and apparatus for filling an ion detector cell
GB201018184D0 (en) * 2010-10-27 2010-12-08 Micromass Ltd Asymmetric field ion mobility in a linear geometry ion trap
GB201104220D0 (en) * 2011-03-14 2011-04-27 Micromass Ltd Ion guide with orthogonal sampling
US8299443B1 (en) 2011-04-14 2012-10-30 Battelle Memorial Institute Microchip and wedge ion funnels and planar ion beam analyzers using same
CN107633995B (zh) * 2011-05-05 2019-08-06 岛津研究实验室（欧洲）有限公司 操纵带电粒子的装置
US8927940B2 (en) * 2011-06-03 2015-01-06 Bruker Daltonics, Inc. Abridged multipole structure for the transport, selection and trapping of ions in a vacuum system
US9184040B2 (en) * 2011-06-03 2015-11-10 Bruker Daltonics, Inc. Abridged multipole structure for the transport and selection of ions in a vacuum system
GB201122251D0 (en) * 2011-12-23 2012-02-01 Micromass Ltd Multi-pass ion mobility separation device
US8859961B2 (en) * 2012-01-06 2014-10-14 Agilent Technologies, Inc. Radio frequency (RF) ion guide for improved performance in mass spectrometers
US8507848B1 (en) * 2012-01-24 2013-08-13 Shimadzu Research Laboratory (Shanghai) Co. Ltd. Wire electrode based ion guide device
CA2863300A1 (en) * 2012-02-01 2013-08-08 Dh Technologies Development Pte. Ltd. Method and apparatus for improved sensitivity in a mass spectrometer
GB2509412B (en) * 2012-02-21 2016-06-01 Thermo Fisher Scient (Bremen) Gmbh Apparatus and methods for ion mobility spectrometry
US8637817B1 (en) * 2013-03-01 2014-01-28 The Rockefeller University Multi-pole ion trap for mass spectrometry
US8835839B1 (en) 2013-04-08 2014-09-16 Battelle Memorial Institute Ion manipulation device
US9812311B2 (en) * 2013-04-08 2017-11-07 Battelle Memorial Institute Ion manipulation method and device
US9324548B1 (en) 2014-05-08 2016-04-26 Bruker Daltonik Gmbh Method and device to increase the internal energy of ions in mass spectrometers
US9613788B2 (en) * 2014-06-13 2017-04-04 Perkinelmer Health Sciences, Inc. RF ion guide with axial fields
CN105470094B (zh) * 2014-09-04 2018-03-09 株式会社岛津制作所 离子光学装置及质谱仪
US20160181080A1 (en) 2014-12-23 2016-06-23 Agilent Technologies, Inc. Multipole ion guides utilizing segmented and helical electrodes, and related systems and methods
US9972480B2 (en) * 2015-01-30 2018-05-15 Agilent Technologies, Inc. Pulsed ion guides for mass spectrometers and related methods
US9761427B2 (en) 2015-04-29 2017-09-12 Thermo Finnigan Llc System for transferring ions in a mass spectrometer
US9704701B2 (en) 2015-09-11 2017-07-11 Battelle Memorial Institute Method and device for ion mobility separations
US10458944B2 (en) 2016-06-03 2019-10-29 Bruker Daltonik Gmbh Trapped ion mobility spectrometer with high ion storage capacity
US10224194B2 (en) 2016-09-08 2019-03-05 Battelle Memorial Institute Device to manipulate ions of same or different polarities
US10460920B1 (en) * 2018-06-26 2019-10-29 Battelle Memorial Institute Flexible ion conduit

Also Published As

Publication number Publication date
CA3035818A1 (en) 2018-03-15
EP3510626A1 (en) 2019-07-17
JP6905587B2 (ja) 2021-07-21
WO2018048494A1 (en) 2018-03-15
CA3035818C (en) 2023-06-27
US20180068839A1 (en) 2018-03-08
US20190198305A1 (en) 2019-06-27
US10665443B2 (en) 2020-05-26
US10224194B2 (en) 2019-03-05
JP2019530148A (ja) 2019-10-17

Similar Documents

Publication Publication Date Title
SG11201901783UA (en) A device to manipulate ions of same or different polarities
SG11201810023QA (en) Anti-tim-3 antibodies and methods of use thereof
SG11201810264TA (en) Method and apparatus for spatial compression and increased mobility resolution of ions
SG11201806190TA (en) Isotachophoresis for purification of nucleic acids
SG11201901531TA (en) Regulation of gene expression using engineered nucleases
SG11201907477VA (en) Half-cell electrochemical configurations for self-cleaning electrochlorination devices
SG11201901364VA (en) Engineered target specific nucleases
SG11201807421TA (en) The use of glucocorticoid receptor modulators to potentiate checkpoint inhibitors
SG11201908719QA (en) Biomarkers and car t cell therapies with enhanced efficacy
SG11201808196UA (en) Neoantigens and methods of their use
SG11201805888SA (en) Cyclic dinucleotides for treating conditions associated with sting activity such as cancer
SG11201808959QA (en) Analyte detection methods and apparatus using dielectrophoresis and electroosmosis
SG11201900269XA (en) Channel sensing for independent links
SG11201900804WA (en) System and method for generating multi-channel tunable illumination from a broadband source
SG11201906200WA (en) Nucleic acid-polypeptide compositions and methods of inducing exon skipping
SG11202000287RA (en) Concept for generating an enhanced sound-field description or a modified sound field description using a depth-extended dirac technique or other techniques
SG11201809374VA (en) Cd40l-fc fusion polypeptides and methods of use thereof
SG11201908478SA (en) Sterilisation method
SG11201804506RA (en) Systems and methods for rendering multiple levels of detail
SG11201804901WA (en) Compounds for the treatment of cancer and inflammatory disease
SG11201900509YA (en) Simultaneous capturing of overlay signals from multiple targets
SG11201906853QA (en) Anti-rsv monoclonal antibody formulation
SG11201909064RA (en) Combination of an anti-pd-l1 antibody and a dna-pk inhibitor for the treatment of cancer
SG11201808672TA (en) Device for sampling one or more analytes
SG11201907764PA (en) Methods for screening infections