CA3035818C - A device to manipulate ions of same or different polarities - Google Patents
A device to manipulate ions of same or different polarities Download PDFInfo
- Publication number
- CA3035818C CA3035818C CA3035818A CA3035818A CA3035818C CA 3035818 C CA3035818 C CA 3035818C CA 3035818 A CA3035818 A CA 3035818A CA 3035818 A CA3035818 A CA 3035818A CA 3035818 C CA3035818 C CA 3035818C
- Authority
- CA
- Canada
- Prior art keywords
- electrodes
- pair
- opposing electrode
- confinement
- arrangement
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0095—Particular arrangements for generating, introducing or analyzing both positive and negative analyte ions
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/06—Electron- or ion-optical arrangements
- H01J49/062—Ion guides
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/06—Electron- or ion-optical arrangements
- H01J49/062—Ion guides
- H01J49/063—Multipole ion guides, e.g. quadrupoles, hexapoles
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/06—Electron- or ion-optical arrangements
- H01J49/062—Ion guides
- H01J49/065—Ion guides having stacked electrodes, e.g. ring stack, plate stack
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
- H01J49/4205—Device types
- H01J49/422—Two-dimensional RF ion traps
- H01J49/4235—Stacked rings or stacked plates
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Electron Tubes For Measurement (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/260,046 | 2016-09-08 | ||
| US15/260,046 US10224194B2 (en) | 2016-09-08 | 2016-09-08 | Device to manipulate ions of same or different polarities |
| PCT/US2017/039770 WO2018048494A1 (en) | 2016-09-08 | 2017-06-28 | A device to manipulate ions of same or different polarities |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA3035818A1 CA3035818A1 (en) | 2018-03-15 |
| CA3035818C true CA3035818C (en) | 2023-06-27 |
Family
ID=59337888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3035818A Active CA3035818C (en) | 2016-09-08 | 2017-06-28 | A device to manipulate ions of same or different polarities |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10224194B2 (https=) |
| EP (1) | EP3510626A1 (https=) |
| JP (1) | JP6905587B2 (https=) |
| CA (1) | CA3035818C (https=) |
| SG (1) | SG11201901783UA (https=) |
| WO (1) | WO2018048494A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10317364B2 (en) | 2015-10-07 | 2019-06-11 | Battelle Memorial Institute | Method and apparatus for ion mobility separations utilizing alternating current waveforms |
| US10224194B2 (en) * | 2016-09-08 | 2019-03-05 | Battelle Memorial Institute | Device to manipulate ions of same or different polarities |
| GB2579314A (en) * | 2017-08-16 | 2020-06-17 | Battelle Memorial Institute | Methods and systems for ion manipulation |
| US10692710B2 (en) * | 2017-08-16 | 2020-06-23 | Battelle Memorial Institute | Frequency modulated radio frequency electric field for ion manipulation |
| EP3692564A1 (en) | 2017-10-04 | 2020-08-12 | Battelle Memorial Institute | Methods and systems for integrating ion manipulation devices |
| US10332723B1 (en) | 2017-12-20 | 2019-06-25 | Battelle Memorial Institute | Ion focusing device |
| US11219393B2 (en) | 2018-07-12 | 2022-01-11 | Trace Matters Scientific Llc | Mass spectrometry system and method for analyzing biological samples |
| US10720315B2 (en) | 2018-06-05 | 2020-07-21 | Trace Matters Scientific Llc | Reconfigurable sequentially-packed ion (SPION) transfer device |
| US10840077B2 (en) | 2018-06-05 | 2020-11-17 | Trace Matters Scientific Llc | Reconfigureable sequentially-packed ion (SPION) transfer device |
| US12089932B2 (en) | 2018-06-05 | 2024-09-17 | Trace Matters Scientific Llc | Apparatus, system, and method for transferring ions |
| US10460920B1 (en) | 2018-06-26 | 2019-10-29 | Battelle Memorial Institute | Flexible ion conduit |
| WO2020237037A1 (en) | 2019-05-21 | 2020-11-26 | MOBILion Systems, Inc. | Voltage control for ion mobility separation |
| US11119069B2 (en) | 2019-05-28 | 2021-09-14 | Battelle Memorial Institute | Device and method to manipulate ions in multi level system |
| GB2586787A (en) * | 2019-08-30 | 2021-03-10 | Shimadzu Corp | Device for performing field asymmetric waveform ion mobility spectrometry |
| GB2586786A (en) * | 2019-08-30 | 2021-03-10 | Shimadzu Corp | Device for performing field asymmetric waveform ion mobility spectrometry |
| WO2021102406A1 (en) | 2019-11-22 | 2021-05-27 | MOBILion Systems, Inc. | Mobility based filtering of ions |
| US12163920B2 (en) | 2020-04-06 | 2024-12-10 | MOBILion Systems, Inc. | Systems and methods for two-dimensional mobility based filtering of ions |
| US11662333B2 (en) | 2020-04-06 | 2023-05-30 | MOBILion Systems, Inc. | Systems and methods for two-dimensional mobility based filtering of ions |
| US12354835B2 (en) * | 2020-05-07 | 2025-07-08 | Battelle Memorial Institute | Systems and methods for selective molecular ion deposition |
| CN115885176A (zh) | 2020-05-22 | 2023-03-31 | 莫比莱昂系统有限公司 | 用于俘获和积累离子的方法和装置 |
| WO2021247820A1 (en) | 2020-06-05 | 2021-12-09 | MOBILion Systems, Inc. | Apparatus and methods for ion manipulation having improved duty cycle |
| WO2022147201A1 (en) | 2020-12-31 | 2022-07-07 | Mobliion Systems, Inc. | Systems and methods for extracting ions from a gas flow |
| US12327651B2 (en) * | 2021-08-19 | 2025-06-10 | Quantinuum Llc | Periodic multi-dimensional atomic object confinement apparatus having curved legs |
| CN116153759B (zh) * | 2023-02-15 | 2026-03-27 | 西安电子科技大学 | 一种横向堆叠结构的无门化离子迁移管 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19523859C2 (de) | 1995-06-30 | 2000-04-27 | Bruker Daltonik Gmbh | Vorrichtung für die Reflektion geladener Teilchen |
| GB9519033D0 (en) | 1995-09-18 | 1995-11-15 | Smithkline Beecham Plc | Treatment |
| MXPA02001588A (es) | 1999-08-16 | 2002-07-02 | Univ Johns Hopkins | Reflectron de iones, que comprende unt ablero flexible de circuito impreso. |
| US6593570B2 (en) * | 2000-05-24 | 2003-07-15 | Agilent Technologies, Inc. | Ion optic components for mass spectrometers |
| CA2391140C (en) | 2001-06-25 | 2008-10-07 | Micromass Limited | Mass spectrometer |
| US7095013B2 (en) | 2002-05-30 | 2006-08-22 | Micromass Uk Limited | Mass spectrometer |
| US20040195503A1 (en) | 2003-04-04 | 2004-10-07 | Taeman Kim | Ion guide for mass spectrometers |
| GB0514964D0 (en) * | 2005-07-21 | 2005-08-24 | Ms Horizons Ltd | Mass spectrometer devices & methods of performing mass spectrometry |
| GB0403533D0 (en) | 2004-02-18 | 2004-03-24 | Hoffman Andrew | Mass spectrometer |
| US7365317B2 (en) | 2004-05-21 | 2008-04-29 | Analytica Of Branford, Inc. | RF surfaces and RF ion guides |
| DE102004048496B4 (de) | 2004-10-05 | 2008-04-30 | Bruker Daltonik Gmbh | Ionenführung mit HF-Blendenstapeln |
| GB0426520D0 (en) * | 2004-12-02 | 2005-01-05 | Micromass Ltd | Mass spectrometer |
| GB0427634D0 (en) | 2004-12-17 | 2005-01-19 | Micromass Ltd | Mass spectrometer |
| EP1956635B1 (en) | 2005-11-28 | 2013-05-15 | Hitachi, Ltd. | Ion guide device, ion reactor, and mass analyzer |
| US7548818B2 (en) | 2005-12-07 | 2009-06-16 | Mds Analytical Technologies | Automated analysis of complex matrices using mass spectrometer |
| CN101416271B (zh) * | 2006-05-22 | 2010-07-14 | 株式会社岛津制作所 | 平行板电极布置设备和方法 |
| GB2451239B (en) * | 2007-07-23 | 2009-07-08 | Microsaic Systems Ltd | Microengineered electrode assembly |
| GB0718468D0 (en) | 2007-09-21 | 2007-10-31 | Micromass Ltd | Mass spectrometer |
| GB0723183D0 (en) * | 2007-11-23 | 2008-01-09 | Micromass Ltd | Mass spectrometer |
| US7888635B2 (en) | 2008-05-30 | 2011-02-15 | Battelle Memorial Institute | Ion funnel ion trap and process |
| CN102150219B (zh) | 2008-07-28 | 2015-01-28 | 莱克公司 | 在射频场中使用网的离子操纵的方法和设备 |
| US7838826B1 (en) | 2008-08-07 | 2010-11-23 | Bruker Daltonics, Inc. | Apparatus and method for parallel flow ion mobility spectrometry combined with mass spectrometry |
| US8309911B2 (en) * | 2009-08-25 | 2012-11-13 | Agilent Technologies, Inc. | Methods and apparatus for filling an ion detector cell |
| GB201018184D0 (en) * | 2010-10-27 | 2010-12-08 | Micromass Ltd | Asymmetric field ion mobility in a linear geometry ion trap |
| GB201104220D0 (en) * | 2011-03-14 | 2011-04-27 | Micromass Ltd | Ion guide with orthogonal sampling |
| US8299443B1 (en) | 2011-04-14 | 2012-10-30 | Battelle Memorial Institute | Microchip and wedge ion funnels and planar ion beam analyzers using same |
| CN107633995B (zh) * | 2011-05-05 | 2019-08-06 | 岛津研究实验室(欧洲)有限公司 | 操纵带电粒子的装置 |
| US8927940B2 (en) * | 2011-06-03 | 2015-01-06 | Bruker Daltonics, Inc. | Abridged multipole structure for the transport, selection and trapping of ions in a vacuum system |
| US9184040B2 (en) * | 2011-06-03 | 2015-11-10 | Bruker Daltonics, Inc. | Abridged multipole structure for the transport and selection of ions in a vacuum system |
| GB201122251D0 (en) * | 2011-12-23 | 2012-02-01 | Micromass Ltd | Multi-pass ion mobility separation device |
| US8859961B2 (en) * | 2012-01-06 | 2014-10-14 | Agilent Technologies, Inc. | Radio frequency (RF) ion guide for improved performance in mass spectrometers |
| US8507848B1 (en) * | 2012-01-24 | 2013-08-13 | Shimadzu Research Laboratory (Shanghai) Co. Ltd. | Wire electrode based ion guide device |
| CA2863300A1 (en) * | 2012-02-01 | 2013-08-08 | Dh Technologies Development Pte. Ltd. | Method and apparatus for improved sensitivity in a mass spectrometer |
| GB2509412B (en) * | 2012-02-21 | 2016-06-01 | Thermo Fisher Scient (Bremen) Gmbh | Apparatus and methods for ion mobility spectrometry |
| US8637817B1 (en) * | 2013-03-01 | 2014-01-28 | The Rockefeller University | Multi-pole ion trap for mass spectrometry |
| US8835839B1 (en) | 2013-04-08 | 2014-09-16 | Battelle Memorial Institute | Ion manipulation device |
| US9812311B2 (en) * | 2013-04-08 | 2017-11-07 | Battelle Memorial Institute | Ion manipulation method and device |
| US9324548B1 (en) | 2014-05-08 | 2016-04-26 | Bruker Daltonik Gmbh | Method and device to increase the internal energy of ions in mass spectrometers |
| US9613788B2 (en) * | 2014-06-13 | 2017-04-04 | Perkinelmer Health Sciences, Inc. | RF ion guide with axial fields |
| CN105470094B (zh) * | 2014-09-04 | 2018-03-09 | 株式会社岛津制作所 | 离子光学装置及质谱仪 |
| US20160181080A1 (en) | 2014-12-23 | 2016-06-23 | Agilent Technologies, Inc. | Multipole ion guides utilizing segmented and helical electrodes, and related systems and methods |
| US9972480B2 (en) * | 2015-01-30 | 2018-05-15 | Agilent Technologies, Inc. | Pulsed ion guides for mass spectrometers and related methods |
| US9761427B2 (en) | 2015-04-29 | 2017-09-12 | Thermo Finnigan Llc | System for transferring ions in a mass spectrometer |
| US9704701B2 (en) | 2015-09-11 | 2017-07-11 | Battelle Memorial Institute | Method and device for ion mobility separations |
| US10458944B2 (en) | 2016-06-03 | 2019-10-29 | Bruker Daltonik Gmbh | Trapped ion mobility spectrometer with high ion storage capacity |
| US10224194B2 (en) | 2016-09-08 | 2019-03-05 | Battelle Memorial Institute | Device to manipulate ions of same or different polarities |
| US10460920B1 (en) * | 2018-06-26 | 2019-10-29 | Battelle Memorial Institute | Flexible ion conduit |
-
2016
- 2016-09-08 US US15/260,046 patent/US10224194B2/en active Active
-
2017
- 2017-06-28 JP JP2019513032A patent/JP6905587B2/ja active Active
- 2017-06-28 WO PCT/US2017/039770 patent/WO2018048494A1/en not_active Ceased
- 2017-06-28 CA CA3035818A patent/CA3035818C/en active Active
- 2017-06-28 SG SG11201901783UA patent/SG11201901783UA/en unknown
- 2017-06-28 EP EP17739797.3A patent/EP3510626A1/en not_active Withdrawn
-
2019
- 2019-02-28 US US16/289,216 patent/US10665443B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA3035818A1 (en) | 2018-03-15 |
| EP3510626A1 (en) | 2019-07-17 |
| JP6905587B2 (ja) | 2021-07-21 |
| WO2018048494A1 (en) | 2018-03-15 |
| US20180068839A1 (en) | 2018-03-08 |
| US20190198305A1 (en) | 2019-06-27 |
| SG11201901783UA (en) | 2019-03-28 |
| US10665443B2 (en) | 2020-05-26 |
| US10224194B2 (en) | 2019-03-05 |
| JP2019530148A (ja) | 2019-10-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20220624 |
|
| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 8TH ANNIV.) - STANDARD Year of fee payment: 8 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20250509 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20250509 |