SG11201811220UA - Methods, systems and devices for concentration of particles - Google Patents

Methods, systems and devices for concentration of particles

Info

Publication number
SG11201811220UA
SG11201811220UA SG11201811220UA SG11201811220UA SG11201811220UA SG 11201811220U A SG11201811220U A SG 11201811220UA SG 11201811220U A SG11201811220U A SG 11201811220UA SG 11201811220U A SG11201811220U A SG 11201811220UA SG 11201811220U A SG11201811220U A SG 11201811220UA
Authority
SG
Singapore
Prior art keywords
particles
international
carlsbad
california
life technologies
Prior art date
Application number
SG11201811220UA
Other languages
English (en)
Inventor
Michael Ward
Saul Selberg
Jason Malkin
Ken Lefton
Original Assignee
Life Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Technologies Corp filed Critical Life Technologies Corp
Publication of SG11201811220UA publication Critical patent/SG11201811220UA/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/28Magnetic plugs and dipsticks
    • B03C1/288Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/025High gradient magnetic separators
    • B03C1/031Component parts; Auxiliary operations
    • B03C1/033Component parts; Auxiliary operations characterised by the magnetic circuit
    • B03C1/0332Component parts; Auxiliary operations characterised by the magnetic circuit using permanent magnets
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/025High gradient magnetic separators
    • B03C1/031Component parts; Auxiliary operations
    • B03C1/033Component parts; Auxiliary operations characterised by the magnetic circuit
    • B03C1/0335Component parts; Auxiliary operations characterised by the magnetic circuit using coils
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404Handling flow, e.g. hydrodynamic focusing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/046Function or devices integrated in the closure
    • B01L2300/047Additional chamber, reservoir
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/18Magnetic separation whereby the particles are suspended in a liquid
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1006Investigating individual particles for cytology
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404Handling flow, e.g. hydrodynamic focusing
    • G01N2015/142Acoustic or ultrasonic focussing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Fluid Mechanics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Separation Of Solids By Using Liquids Or Pneumatic Power (AREA)
  • Filtration Of Liquid (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Financial Or Insurance-Related Operations Such As Payment And Settlement (AREA)
SG11201811220UA 2016-07-01 2017-06-30 Methods, systems and devices for concentration of particles SG11201811220UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662357440P 2016-07-01 2016-07-01
PCT/US2017/040322 WO2018005984A1 (fr) 2016-07-01 2017-06-30 Procédés, systèmes et dispositifs de concentration de particules

Publications (1)

Publication Number Publication Date
SG11201811220UA true SG11201811220UA (en) 2019-01-30

Family

ID=59521630

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201811220UA SG11201811220UA (en) 2016-07-01 2017-06-30 Methods, systems and devices for concentration of particles

Country Status (6)

Country Link
US (1) US11020745B2 (fr)
EP (1) EP3479097B1 (fr)
JP (1) JP7026063B2 (fr)
CN (1) CN109416314A (fr)
SG (1) SG11201811220UA (fr)
WO (1) WO2018005984A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018096005A1 (fr) 2016-11-24 2018-05-31 Koninklijke Philips N.V. Dispositif, procédé de système et nécessaire pour isoler une substance à analyser dans un échantillon de liquide organique
CN111630364A (zh) * 2018-01-29 2020-09-04 惠普发展公司,有限责任合伙企业 颗粒分类
EP3647767B1 (fr) * 2018-10-30 2024-09-25 Siemens Healthineers AG Embillage isovolumètrique de cellules de sang rouges
US11988557B2 (en) 2021-12-08 2024-05-21 Battelle Savannah River Alliance, Llc Electric field detection method and system

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7340957B2 (en) * 2004-07-29 2008-03-11 Los Alamos National Security, Llc Ultrasonic analyte concentration and application in flow cytometry
WO2006079007A2 (fr) * 2005-01-21 2006-07-27 President And Fellows Of Harvard College Microconcentrateur/microfiltre
WO2007044642A2 (fr) * 2005-10-06 2007-04-19 President And Fellows Of Harvard College And Children's Medical Center Corporation Dispositif et procede destines a la separation microfluidique-micromagnetique combinee d'une substance a partir d'un ecoulement continu
EP1979467B1 (fr) * 2006-01-19 2012-10-17 Yeda Research And Development Co., Ltd. Dispositif et méthode destinés à manipuler des particules dans un fluide
WO2008122051A1 (fr) * 2007-04-02 2008-10-09 Acoustic Cytometry Systems, Inc. Procédés et dispositifs pour l'analyse amplifiée de cellules et particules focalisées sur champ
US7837040B2 (en) 2007-04-09 2010-11-23 Los Alamos National Security, Llc Acoustic concentration of particles in fluid flow
JP5172946B2 (ja) * 2007-04-16 2013-03-27 ザ ジェネラル ホスピタル コーポレーション ドゥーイング ビジネス アズ マサチューセッツ ジェネラル ホスピタル マイクロチャネルにおける粒子集束のためのシステムおよび方法
EP2145687B1 (fr) * 2007-05-15 2014-12-03 Panasonic Corporation Dispositif de séparation de composant
US8266951B2 (en) * 2007-12-19 2012-09-18 Los Alamos National Security, Llc Particle analysis in an acoustic cytometer
CN102762990B (zh) * 2009-12-04 2014-10-29 生命技术公司 用于声学流式细胞计量术的装置、系统、方法和计算机可读介质
US9821310B2 (en) * 2011-03-31 2017-11-21 The University Of Akron Two-stage microfluidic device for acoustic particle manipulation and methods of separation
WO2013116311A1 (fr) * 2012-01-31 2013-08-08 The Penn State Research Foundation Manipulation microfluidique et tri de particules à l'aide d'une onde acoustique de surface stationnaire et synchronisable
US9764304B2 (en) 2012-05-14 2017-09-19 Empire Technology Development Llc Acoustically driven nanoparticle concentrator
KR101920732B1 (ko) * 2013-03-14 2018-11-22 인구란, 엘엘씨 높은 처리량의 정자 분류 장치 및 방법
US9645080B2 (en) 2013-04-16 2017-05-09 University Of Washington Systems, devices, and methods for separating, concentrating, and/or differentiating between cells from a cell sample
JP6104475B2 (ja) 2014-08-28 2017-04-05 シスメックス株式会社 粒子撮像装置および粒子撮像方法

Also Published As

Publication number Publication date
US11020745B2 (en) 2021-06-01
CN109416314A (zh) 2019-03-01
US20190126276A1 (en) 2019-05-02
WO2018005984A1 (fr) 2018-01-04
EP3479097B1 (fr) 2023-07-12
JP2019530850A (ja) 2019-10-24
JP7026063B2 (ja) 2022-02-25
EP3479097A1 (fr) 2019-05-08

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