SG11201809575TA - Biocatalysts and methods for hydroxylation of chemical compounds - Google Patents
Biocatalysts and methods for hydroxylation of chemical compoundsInfo
- Publication number
- SG11201809575TA SG11201809575TA SG11201809575TA SG11201809575TA SG11201809575TA SG 11201809575T A SG11201809575T A SG 11201809575TA SG 11201809575T A SG11201809575T A SG 11201809575TA SG 11201809575T A SG11201809575T A SG 11201809575TA SG 11201809575T A SG11201809575T A SG 11201809575TA
- Authority
- SG
- Singapore
- Prior art keywords
- california
- penobscot
- rpm
- international
- air
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 102000004190 Enzymes Human genes 0.000 title abstract 2
- 108090000790 Enzymes Proteins 0.000 title abstract 2
- 239000011942 biocatalyst Substances 0.000 title abstract 2
- 230000033444 hydroxylation Effects 0.000 title abstract 2
- 238000005805 hydroxylation reaction Methods 0.000 title abstract 2
- 102000004079 Prolyl Hydroxylases Human genes 0.000 abstract 4
- 108010043005 Prolyl Hydroxylases Proteins 0.000 abstract 4
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 240000005020 Acaciella glauca Species 0.000 abstract 2
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 2
- 239000004472 Lysine Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 235000003499 redwood Nutrition 0.000 abstract 2
- 230000008520 organization Effects 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000002023 wood Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
- C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/11—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (1.14.11)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/11—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (1.14.11)
- C12Y114/11002—Procollagen-proline dioxygenase (1.14.11.2), i.e. proline-hydroxylase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662347724P | 2016-06-09 | 2016-06-09 | |
| PCT/US2017/028370 WO2017213758A1 (en) | 2016-06-09 | 2017-04-19 | Biocatalysts and methods for hydroxylation of chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201809575TA true SG11201809575TA (en) | 2018-11-29 |
Family
ID=60572322
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201809575TA SG11201809575TA (en) | 2016-06-09 | 2017-04-19 | Biocatalysts and methods for hydroxylation of chemical compounds |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US10184117B2 (zh) |
| EP (1) | EP3469088B1 (zh) |
| CN (1) | CN109715817B (zh) |
| IL (1) | IL263448B2 (zh) |
| SG (1) | SG11201809575TA (zh) |
| WO (1) | WO2017213758A1 (zh) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109715817B (zh) * | 2016-06-09 | 2022-12-09 | 科德克希思公司 | 用于化合物的羟基化的生物催化剂和方法 |
| CN106834244B (zh) * | 2016-11-04 | 2021-07-06 | 凯莱英医药集团（天津）股份有限公司 | 脯氨酸羟化酶及其应用 |
| CN113046251B (zh) * | 2019-12-27 | 2023-01-24 | 上海医药工业研究院 | 生产纽莫康定b0的基因工程菌、其制备方法及应用 |
| CN113046250B (zh) * | 2019-12-27 | 2023-01-24 | 上海医药工业研究院 | 生产纽莫康定b0的基因工程菌及其制备方法和应用 |
| US11767519B2 (en) | 2020-08-28 | 2023-09-26 | Codexis, Inc. | Engineered amylase variants |
| EP4204554A1 (en) | 2020-08-28 | 2023-07-05 | Codexis, Inc. | Engineered protease variants |
| WO2022104385A2 (en) * | 2020-11-13 | 2022-05-19 | The Regents Of The University Of Colorado, A Body Corporate | Stability and activity of enzymes by immobilization |
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| CN109715817B (zh) * | 2016-06-09 | 2022-12-09 | 科德克希思公司 | 用于化合物的羟基化的生物催化剂和方法 |
| EP3536780A4 (en) * | 2016-11-04 | 2020-06-17 | Asymchem Laboratories (Tianjin) Co., Ltd. | PROLINHYDROXYLASE AND APPLICATION THEREOF |
-
2017
- 2017-04-19 CN CN201780048037.3A patent/CN109715817B/zh active Active
- 2017-04-19 IL IL263448A patent/IL263448B2/en unknown
- 2017-04-19 SG SG11201809575TA patent/SG11201809575TA/en unknown
- 2017-04-19 WO PCT/US2017/028370 patent/WO2017213758A1/en unknown
- 2017-04-19 EP EP17810674.6A patent/EP3469088B1/en active Active
- 2017-04-19 US US15/491,692 patent/US10184117B2/en active Active
-
2018
- 2018-11-20 US US16/196,205 patent/US10844358B2/en active Active
-
2020
- 2020-10-16 US US17/072,910 patent/US11634695B2/en active Active
-
2023
- 2023-03-08 US US18/180,711 patent/US20230272354A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20230272354A1 (en) | 2023-08-31 |
| EP3469088A1 (en) | 2019-04-17 |
| US10844358B2 (en) | 2020-11-24 |
| CN109715817A (zh) | 2019-05-03 |
| US20170355968A1 (en) | 2017-12-14 |
| US20210032605A1 (en) | 2021-02-04 |
| US10184117B2 (en) | 2019-01-22 |
| EP3469088B1 (en) | 2023-09-06 |
| US20190078061A1 (en) | 2019-03-14 |
| IL263448A (en) | 2019-02-03 |
| CN109715817B (zh) | 2022-12-09 |
| EP3469088C0 (en) | 2023-09-06 |
| EP3469088A4 (en) | 2020-04-01 |
| IL263448B2 (en) | 2023-10-01 |
| WO2017213758A1 (en) | 2017-12-14 |
| IL263448B1 (en) | 2023-06-01 |
| US11634695B2 (en) | 2023-04-25 |
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