SG11201809483UA - Production of steviol glycosides in recombinant hosts - Google Patents

Production of steviol glycosides in recombinant hosts

Info

Publication number
SG11201809483UA
SG11201809483UA SG11201809483UA SG11201809483UA SG11201809483UA SG 11201809483U A SG11201809483U A SG 11201809483UA SG 11201809483U A SG11201809483U A SG 11201809483UA SG 11201809483U A SG11201809483U A SG 11201809483UA SG 11201809483U A SG11201809483U A SG 11201809483UA
Authority
SG
Singapore
Prior art keywords
international
steviol
copenhagen
pct
glycosides
Prior art date
Application number
SG11201809483UA
Other languages
English (en)
Inventor
Iver Klavs Riishede Hansen
Veronique Douchin
Jens Houghton-Larsen
Esben Halkjaer Hansen
Angelika Semmler
Laura Occhipinti
Kim Olsson
Original Assignee
Evolva Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evolva Sa filed Critical Evolva Sa
Publication of SG11201809483UA publication Critical patent/SG11201809483UA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/56Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
SG11201809483UA 2016-05-16 2017-05-16 Production of steviol glycosides in recombinant hosts SG11201809483UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662337213P 2016-05-16 2016-05-16
PCT/EP2017/061774 WO2017198681A1 (fr) 2016-05-16 2017-05-16 Production de glycosides de stéviol dans des hôtes de recombinaison

Publications (1)

Publication Number Publication Date
SG11201809483UA true SG11201809483UA (en) 2018-11-29

Family

ID=58739035

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201809483UA SG11201809483UA (en) 2016-05-16 2017-05-16 Production of steviol glycosides in recombinant hosts

Country Status (9)

Country Link
US (2) US20190144907A1 (fr)
EP (1) EP3458598A1 (fr)
JP (1) JP2019519212A (fr)
CN (1) CN109477128A (fr)
AU (1) AU2017267214A1 (fr)
BR (1) BR112018073662A2 (fr)
CA (1) CA3023399A1 (fr)
SG (1) SG11201809483UA (fr)
WO (1) WO2017198681A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY194280A (en) 2016-08-12 2022-11-25 Amyris Inc Udp-dependent glycosyltransferase for high efficiency production of rebaudiosides
CA3039105C (fr) * 2016-10-14 2024-03-05 Conagen Inc. Production biosynthetique de glycosides de steviol et procedes associes
BR112020009838A2 (pt) * 2017-12-05 2020-11-17 Evolva Sa produção de glicosídeos de esteviol em hospedeiros recombinantes
KR20210027270A (ko) * 2018-06-08 2021-03-10 퓨어써클 유에스에이 잉크. 고순도 스테비올 글리코사이드
CN110564658B (zh) * 2019-09-06 2021-08-17 广西大学 一株大肠杆菌工程菌及其全细胞催化生产甜菊醇的方法
CN112760301B (zh) * 2019-11-01 2023-01-17 中国科学院天津工业生物技术研究所 一种催化活性提高的糖基转移酶突变体及其应用
CN111235124B (zh) * 2020-01-19 2023-04-07 云南农业大学 珠子参糖基转移酶UGTPjm2及其在制备竹节参皂苷IVa上的应用
US11396646B2 (en) * 2020-05-29 2022-07-26 QTG Development, Inc. Steviol glycosyltransferases and genes encoding the same
CN113308447B (zh) * 2021-05-31 2022-09-30 西南大学 拟南芥ugt74f2在催化苯乳酸合成苯乳酰葡萄糖中的应用
CN114736887A (zh) * 2022-03-25 2022-07-12 上海威高医疗技术发展有限公司 羧酸酯酶的用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009034080A (ja) * 2007-08-03 2009-02-19 Sanei Gen Ffi Inc 新規糖転移酵素、及びそれを利用した配糖体の製造
CN105671108A (zh) * 2010-06-02 2016-06-15 沃维公司 甜菊糖苷的重组生产
EP3009508B1 (fr) * 2011-08-08 2020-11-25 Evolva SA Production recombinante de glycosides de stéviol
AU2012342114B2 (en) * 2011-11-23 2017-12-21 Evolva Sa Methods and materials for enzymatic synthesis of mogroside compounds
MX367859B (es) * 2012-12-04 2019-09-09 Evolva Sa Metodos y materiales para la biosintesis de compuestos mogrosidos.
CN105051195B (zh) * 2013-02-06 2019-09-06 埃沃尔瓦公司 用于提高莱鲍迪苷d和莱鲍迪苷m之产生的方法
US20160215306A1 (en) * 2013-08-30 2016-07-28 Evolva Sa Method for producing modified resveratrol
EP3114210A2 (fr) * 2014-03-07 2017-01-11 Evolva SA Procédés de production recombinante de composés du safran
AU2015314251A1 (en) * 2014-09-09 2017-03-16 Evolva Sa Production of steviol glycosides in recombinant hosts
CN104845990A (zh) * 2015-06-11 2015-08-19 山东大学 拟南芥糖基转移酶基因ugt73c7在提高植物抗病性中的应用

Also Published As

Publication number Publication date
WO2017198681A1 (fr) 2017-11-23
CN109477128A (zh) 2019-03-15
BR112018073662A2 (pt) 2019-02-19
US20220154234A1 (en) 2022-05-19
JP2019519212A (ja) 2019-07-11
AU2017267214A1 (en) 2018-11-15
US20190144907A1 (en) 2019-05-16
CA3023399A1 (fr) 2017-11-23
EP3458598A1 (fr) 2019-03-27

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