SG11201808957UA - Penicillin-g acylases - Google Patents

Penicillin-g acylases

Info

Publication number
SG11201808957UA
SG11201808957UA SG11201808957UA SG11201808957UA SG11201808957UA SG 11201808957U A SG11201808957U A SG 11201808957UA SG 11201808957U A SG11201808957U A SG 11201808957UA SG 11201808957U A SG11201808957U A SG 11201808957UA SG 11201808957U A SG11201808957U A SG 11201808957UA
Authority
SG
Singapore
Prior art keywords
california
penobscot
drive
city
international
Prior art date
Application number
SG11201808957UA
Other languages
English (en)
Inventor
Jovana Nazor
Vesna Mitchell
David Elgart
Katrina Lexa
Nikki Dellas
Robert Orr
Oscar Alvizo
Ravi Garcia
Judy Viduya
Courtney Moffett
Original Assignee
Codexis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codexis Inc filed Critical Codexis Inc
Publication of SG11201808957UA publication Critical patent/SG11201808957UA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/84—Penicillin amidase (3.5.1.11)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01011—Penicillin amidase (3.5.1.11), i.e. penicillin-amidohydrolase
SG11201808957UA 2016-05-05 2017-05-05 Penicillin-g acylases SG11201808957UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662332103P 2016-05-05 2016-05-05
PCT/US2017/031342 WO2017193022A1 (en) 2016-05-05 2017-05-05 Penicillin-g acylases

Publications (1)

Publication Number Publication Date
SG11201808957UA true SG11201808957UA (en) 2018-11-29

Family

ID=60203339

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201808957UA SG11201808957UA (en) 2016-05-05 2017-05-05 Penicillin-g acylases

Country Status (12)

Country Link
US (3) US10724025B2 (ko)
EP (1) EP3452587B1 (ko)
JP (1) JP7128519B2 (ko)
KR (1) KR102382489B1 (ko)
CN (1) CN109715793A (ko)
AU (1) AU2017260355B2 (ko)
CA (1) CA3021009A1 (ko)
DK (1) DK3452587T3 (ko)
IL (1) IL262550B (ko)
MX (1) MX2018013259A (ko)
SG (1) SG11201808957UA (ko)
WO (1) WO2017193022A1 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017193022A1 (en) 2016-05-05 2017-11-09 Codexis, Inc. Penicillin-g acylases
CN111051506B (zh) * 2017-06-27 2023-11-24 科德克希思公司 青霉素g酰化酶

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1338400C (en) 1983-08-31 1996-06-18 David H. Gelfand Recombinant fungal cellulases
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6309883B1 (en) 1994-02-17 2001-10-30 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6995017B1 (en) 1994-02-17 2006-02-07 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US6395547B1 (en) 1994-02-17 2002-05-28 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US5834252A (en) 1995-04-18 1998-11-10 Glaxo Group Limited End-complementary polymerase reaction
US6165793A (en) 1996-03-25 2000-12-26 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US20060257890A1 (en) 1996-05-20 2006-11-16 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6406855B1 (en) 1994-02-17 2002-06-18 Maxygen, Inc. Methods and compositions for polypeptide engineering
US5928905A (en) 1995-04-18 1999-07-27 Glaxo Group Limited End-complementary polymerase reaction
DK0765394T3 (da) 1994-06-03 2001-12-10 Novozymes As Oprensede Myceliopthora-laccaser og nukleinsyrer der koder for disse
AU2705895A (en) 1994-06-30 1996-01-25 Novo Nordisk Biotech, Inc. Non-toxic, non-toxigenic, non-pathogenic fusarium expression system and promoters and terminators for use therein
US5646242A (en) * 1994-11-17 1997-07-08 Eli Lilly And Company Selective acylation of epsilon-amino groups
FI104465B (fi) 1995-06-14 2000-02-15 Valio Oy Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö
US6096548A (en) 1996-03-25 2000-08-01 Maxygen, Inc. Method for directing evolution of a virus
US6506602B1 (en) 1996-03-25 2003-01-14 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
DE69738873D1 (de) * 1996-11-05 2008-09-11 Bristol Myers Squibb Co Mutierte penicillin g acylasen
EP1717322B1 (en) 1997-01-17 2012-07-18 Codexis Mayflower Holdings, LLC Evolution of whole cells and organisms by recursive sequence recombination
US6326204B1 (en) 1997-01-17 2001-12-04 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
WO1998031816A1 (en) 1997-01-17 1998-07-23 Regents Of The University Of Minnesota Dna molecules and protein displaying improved triazine compound degrading ability
US7148054B2 (en) 1997-01-17 2006-12-12 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
US6537746B2 (en) 1997-12-08 2003-03-25 Maxygen, Inc. Method for creating polynucleotide and polypeptide sequences
JP2002510506A (ja) 1998-04-02 2002-04-09 テラス ジェネティック リソーシズ，インコーポレイティド 遺伝子配列に遺伝障害を有する植物を得る方法
US6500617B1 (en) 1998-05-01 2002-12-31 Maxygen, Inc. Optimization of pest resistance genes using DNA shuffling
JP2002517995A (ja) 1998-06-17 2002-06-25 マキシジェン， インコーポレイテッド 所望の特性を有するポリヌクレオチドを生成するための方法
US6365408B1 (en) 1998-06-19 2002-04-02 Maxygen, Inc. Methods of evolving a polynucleotides by mutagenesis and recombination
US6605430B1 (en) 1998-08-12 2003-08-12 Maxygen, Inc. DNA shuffling of monooxygenase genes for production of industrial chemicals
CA2345356C (en) 1998-10-06 2012-10-02 Mark Aaron Emalfarb Transformation system in the field of filamentous fungal hosts
CA2345203A1 (en) 1998-10-07 2000-04-13 Maxygen Inc. Dna shuffling to produce nucleic acids for mycotoxin detoxification
WO2000028018A1 (en) 1998-11-10 2000-05-18 Maxygen, Inc. Modified adp-glucose pyrophosphorylase for improvement and optimization of plant phenotypes
JP4221100B2 (ja) 1999-01-13 2009-02-12 エルピーダメモリ株式会社 半導体装置
US6376246B1 (en) 1999-02-05 2002-04-23 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6917882B2 (en) 1999-01-19 2005-07-12 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
US6368861B1 (en) 1999-01-19 2002-04-09 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6436675B1 (en) 1999-09-28 2002-08-20 Maxygen, Inc. Use of codon-varied oligonucleotide synthesis for synthetic shuffling
US7873477B1 (en) 2001-08-21 2011-01-18 Codexis Mayflower Holdings, Llc Method and system using systematically varied data libraries
US8457903B1 (en) 1999-01-19 2013-06-04 Codexis Mayflower Holdings, Llc Method and/or apparatus for determining codons
ATE465459T1 (de) 1999-01-19 2010-05-15 Maxygen Inc Durch oligonukleotide-vermittelte nukleinsäuren- rekombination
US20070065838A1 (en) 1999-01-19 2007-03-22 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6961664B2 (en) 1999-01-19 2005-11-01 Maxygen Methods of populating data structures for use in evolutionary simulations
US7024312B1 (en) 1999-01-19 2006-04-04 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
US7702464B1 (en) 2001-08-21 2010-04-20 Maxygen, Inc. Method and apparatus for codon determining
AR035311A1 (es) * 1999-01-27 2004-05-12 Wyeth Corp Derivados de acido hidroxamico que contienen alquinilo, como inhibidores de las metalloproteinasas de matriz y de la tace, composicion farmaceutica y el uso de los mismos para la manufactura de un medicamento
CA2361384A1 (en) 1999-02-11 2000-08-17 Sun Ai Raillard High throughput mass spectrometry
AU3391900A (en) 1999-03-05 2000-09-21 Maxygen, Inc. Encryption of traits using split gene sequences
US6703240B1 (en) 1999-04-13 2004-03-09 Maxygar, Inc. Modified starch metabolism enzymes and encoding genes for improvement and optimization of plant phenotypes
US7430477B2 (en) 1999-10-12 2008-09-30 Maxygen, Inc. Methods of populating data structures for use in evolutionary simulations
US6519065B1 (en) 1999-11-05 2003-02-11 Jds Fitel Inc. Chromatic dispersion compensation device
US6686515B1 (en) 1999-11-23 2004-02-03 Maxygen, Inc. Homologous recombination in plants
SG121902A1 (en) 2000-01-11 2006-05-26 Maxygen Inc Integrated systems for diversity generation and screening
WO2001075767A2 (en) 2000-03-30 2001-10-11 Maxygen, Inc. In silico cross-over site selection
AU4981101A (en) 2000-04-03 2001-10-15 Maxygen Inc Subtilisin variants
US7783428B2 (en) 2002-03-01 2010-08-24 Maxygen, Inc. Methods, systems, and software for identifying functional biomolecules
US7747391B2 (en) 2002-03-01 2010-06-29 Maxygen, Inc. Methods, systems, and software for identifying functional biomolecules
US20050084907A1 (en) 2002-03-01 2005-04-21 Maxygen, Inc. Methods, systems, and software for identifying functional biomolecules
AU2003213846A1 (en) 2002-03-09 2003-09-29 Maxygen, Inc. Optimization of crossover points for directed evolution
WO2005017135A1 (en) 2003-08-11 2005-02-24 Codexis, Inc. Improved ketoreductase polypeptides and related polynucleotides
JP2007532096A (ja) * 2003-11-14 2007-11-15 ノボ　ノルディスク　アクティーゼルスカブ アシル化されたインスリンの製造方法
US8768871B2 (en) 2008-02-12 2014-07-01 Codexis, Inc. Method of generating an optimized, diverse population of variants
US8504498B2 (en) 2008-02-12 2013-08-06 Codexis, Inc. Method of generating an optimized, diverse population of variants
ES2575005T3 (es) 2008-06-13 2016-06-23 Codexis, Inc. Método de síntesis de variantes de polinucleótidos
US8383346B2 (en) 2008-06-13 2013-02-26 Codexis, Inc. Combined automated parallel synthesis of polynucleotide variants
US20090312196A1 (en) 2008-06-13 2009-12-17 Codexis, Inc. Method of synthesizing polynucleotide variants
WO2010054319A2 (en) 2008-11-10 2010-05-14 Codexis, Inc. Penicillin-g acylases
EP2726651B1 (en) 2011-06-28 2018-11-07 Codexis, Inc. Protein variant generation by region shuffling
SG11201708356PA (en) 2015-05-07 2017-11-29 Codexis Inc Penicillin-g acylases
WO2017193022A1 (en) 2016-05-05 2017-11-09 Codexis, Inc. Penicillin-g acylases

Also Published As

Publication number Publication date
KR102382489B1 (ko) 2022-04-01
KR20180137025A (ko) 2018-12-26
CN109715793A (zh) 2019-05-03
JP7128519B2 (ja) 2022-08-31
US20170321202A1 (en) 2017-11-09
AU2017260355B2 (en) 2023-03-30
US11214786B2 (en) 2022-01-04
IL262550A (en) 2018-12-31
CA3021009A1 (en) 2017-11-09
EP3452587A1 (en) 2019-03-13
US20200339972A1 (en) 2020-10-29
IL262550B (en) 2022-05-01
EP3452587A4 (en) 2020-03-18
US11965192B2 (en) 2024-04-23
WO2017193022A1 (en) 2017-11-09
MX2018013259A (es) 2019-04-22
US20220154164A1 (en) 2022-05-19
EP3452587B1 (en) 2021-09-08
JP2019514395A (ja) 2019-06-06
DK3452587T3 (da) 2021-10-11
AU2017260355A1 (en) 2018-11-01
US10724025B2 (en) 2020-07-28

Similar Documents

Publication Publication Date Title
SG11201906297QA (en) Nucleic acids encoding crispr-associated proteins and uses thereof
SG11201909777YA (en) Modulatory polynucleotides
SG11201908391XA (en) Methods for modulating an immune response
SG11201808812RA (en) Novel aav8 mutant capsids and compositions containing same
SG11201909322VA (en) Treatment of asthma with anti-tslp antibody
SG11201806270XA (en) Gene therapy for treating mucopolysaccharidosis type i
SG11201909955XA (en) Formulations of anti-lag3 antibodies and co-formulations of anti-lag3 antibodies and anti-pd-1 antibodies
SG11201908542QA (en) Gip receptor activating peptide
SG11201906885TA (en) Methods for the administration of certain vmat2 inhibitors
SG11201909949XA (en) Targeted immunotolerance
SG11201806992VA (en) Antibodies to tigit
SG11201807252QA (en) Anti-lag-3 antibodies
SG11201807998WA (en) Treatment Of Inflammatory Diseases With Inhibitors Of C5a Activity
SG11201808176TA (en) Gene therapy for treating mucopolysaccharidosis type ii
SG11201803593QA (en) Engineered nucleic-acid targeting nucleic acids
SG11201907889YA (en) Glycan-interacting compounds and methods of use
SG11201810522UA (en) Anti-cd40 antibodies and their uses
SG11201810757YA (en) Non-human animals expressing exogenous terminal deoxynucleotidyltransferase
SG11201407255XA (en) Stereo widening over arbitrarily-configured loudspeakers
SG11201908602UA (en) Combination therapy for the treatment of solid and hematological cancers
SG11201909957TA (en) Engineered ligase variants
SG11201809497RA (en) Processes for preparing phosphorodiamidate morpholino oligomers
SG11201902531QA (en) Liquid pharmaceutical composition
SG11201803918VA (en) Production of steviol glycosides in recombinant hosts
SG11201809499UA (en) Processes for preparing phosphorodiamidate morpholino oligomers