SG11201805600VA - Deep sequencing profiling of tumors - Google Patents

Deep sequencing profiling of tumors

Info

Publication number
SG11201805600VA
SG11201805600VA SG11201805600VA SG11201805600VA SG11201805600VA SG 11201805600V A SG11201805600V A SG 11201805600VA SG 11201805600V A SG11201805600V A SG 11201805600VA SG 11201805600V A SG11201805600V A SG 11201805600VA SG 11201805600V A SG11201805600V A SG 11201805600VA
Authority
SG
Singapore
Prior art keywords
international
arizona
sequencing
applicants
pct
Prior art date
Application number
SG11201805600VA
Inventor
Nelson Alexander
Daniel Burgess
Stacey Stanislaw
Heidi Rosenbaum
Original Assignee
Ventana Med Syst Inc
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ventana Med Syst Inc, Hoffmann La Roche filed Critical Ventana Med Syst Inc
Publication of SG11201805600VA publication Critical patent/SG11201805600VA/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00—Reactions demanding special reaction conditions
    • C12Q2527/146—Concentration of target or template
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/113—PCR

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
  • Prostheses (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization MD 1111101110101011111 HO 111110111011101111011011 OH III MEV III International Bureau 0.. .... .. (10) International Publication Number (43) International Publication Date ..... ...r .....1 WO 2017/123316 Al 20 July 2017 (20.07.2017) WIPO I PCT (51) (21) (22) (25) Filing Language: (26) Publication Language: (30) International Patent Classification: (71) Applicants (for US only): VENTANA MEDICAL SYS- C12Q 1/68 (2006.01) TEMS, INC. [US/US]; 1910 E. Innovation Park Dr., Tuc- International Application Number: son, Arizona 85755 (US). ROCHE SEQUENCING PCT/US2016/060835 SOLUTIONS, INC. [US/US]; 4300 Hacienda Drive, Pleasanton, California 94588 (US). International Filing Date: (71) Applicants (for DE only): VENTANA MEDICAL SYS- 7 November 2016 (07.11.2016) TEMS, INC. [US/US]; 1910 E. Innovation Park Dr., Tuc- English son, Arizona 85755 (US). ROCHE DIAGNOSTICS GMBH [DE/DE]; Sandhofer Strasse 116, 68305 Man- English nheim (DE). Priority Data: (71) Applicants o r all designated States except DE, US): 62/279,126 15 January 2016 (15.01.2016) US VENTANA MEDICAL SYSTEMS, INC. [US/US]; 1910 62/415,952 1 November 2016 (01.11.2016) US E. Innovation Park Dr., Tucson, Arizona 85755 (US). F. HOFFMANN-LA ROCHE AG [CH/CH]; Grenzacher- strasse 124, 4070 Basel (CH). (72) Inventors: ALEXANDER, Nelson; 11440 N. Vista Ranch Place, Marana, Arizona 85658 (US). BURGESS, Daniel; [Continued on next page] (54) Title: DEEP SEQUENCING PROFILING OF TUMORS (57) such 300 sequencing. 310 320 330 340 . targeted prising : In one aspect of the present disclosure is a sequencing workflow where an input sample com- a sufficient quantity of genomic material is provided minimal or no amplification cycles are utilized prior to Receive a sufficient quantity of genomic materi al Prepare received material for further processing Hybridize genomic material to capture probes Capture hybridized genomic material Sequence hybridized genomic material 1-1 .4 11 M M ei 1-1 IN 1-1 0 ei C FIG. 3A WO 2017/123316 All#110H011010EIR0101301101110110MHIMM0N 500 S. Rosa Road, Madison, Wisconsin 53719 (US). STANISLAW, Stacey; 9971 Rabwa Place, Tucson, Ari- zona 85742 (US). ROSENBAUM, Heidi; 2303 May- SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. wood Circle, Middleton, Wisconsin 53562 (US). (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, (74) (81) Agent: FINETTI, Thomas; Charney IP Law LLC, 233 Mount Airy Road, Suite 100, Basking Ridge, New Jersey 07920 (US). Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, Declarations under Rule 4.17: GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii)) NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, Published: RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, with international search report (Art. 21(3))
SG11201805600VA 2016-01-15 2016-11-07 Deep sequencing profiling of tumors SG11201805600VA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662279126P 2016-01-15 2016-01-15
US201662415952P 2016-11-01 2016-11-01
PCT/US2016/060835 WO2017123316A1 (en) 2016-01-15 2016-11-07 Deep sequencing profiling of tumors

Publications (1)

Publication Number Publication Date
SG11201805600VA true SG11201805600VA (en) 2018-07-30

Family

ID=57396824

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201805600VA SG11201805600VA (en) 2016-01-15 2016-11-07 Deep sequencing profiling of tumors

Country Status (13)

Country Link
US (2) US11649492B2 (en)
EP (1) EP3402896B1 (en)
JP (2) JP7232643B2 (en)
KR (1) KR102398465B1 (en)
CN (1) CN108463559A (en)
AU (1) AU2016386032B2 (en)
BR (1) BR112018014349A2 (en)
CA (1) CA3011342C (en)
IL (1) IL260304A (en)
SA (1) SA518392005B1 (en)
SG (1) SG11201805600VA (en)
WO (1) WO2017123316A1 (en)
ZA (1) ZA201804322B (en)

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JP7232643B2 (en) * 2016-01-15 2023-03-03 ヴェンタナ メディカル システムズ， インク． Deep sequencing profiling of tumors
WO2019067092A1 (en) 2017-08-07 2019-04-04 The Johns Hopkins University Methods and materials for assessing and treating cancer
US20200004928A1 (en) 2018-06-29 2020-01-02 Roche Sequencing Solutions, Inc. Computing device with improved user interface for interpreting and visualizing data
CN109234356B (en) * 2018-09-18 2021-10-08 南京迪康金诺生物技术有限公司 Method for constructing hybridization capture sequencing library and application
WO2020112566A1 (en) 2018-11-29 2020-06-04 Ventana Medical Systems, Inc. Personalized ctdna disease monitoring via representative dna sequencing
CN113228190A (en) 2018-12-23 2021-08-06 豪夫迈·罗氏有限公司 Tumor classification based on predicted tumor mutation burden
WO2020249704A1 (en) 2019-06-13 2020-12-17 F. Hoffmann-La Roche Ag Systems and methods with improved user interface for interpreting and visualizing longitudinal data
EP4342928A1 (en) 2021-05-20 2024-03-27 Agc Inc. Method for producing polycarbonate

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JP7232643B2 (en) * 2016-01-15 2023-03-03 ヴェンタナ メディカル システムズ， インク． Deep sequencing profiling of tumors

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Publication number Publication date
ZA201804322B (en) 2022-10-26
KR102398465B1 (en) 2022-05-13
AU2016386032B2 (en) 2021-08-12
CA3011342A1 (en) 2017-07-20
SA518392005B1 (en) 2022-02-08
KR20180098412A (en) 2018-09-03
US11649492B2 (en) 2023-05-16
IL260304A (en) 2018-08-30
CN108463559A (en) 2018-08-28
US20180320229A1 (en) 2018-11-08
JP2019503182A (en) 2019-02-07
AU2016386032A1 (en) 2018-07-12
EP3402896A1 (en) 2018-11-21
CA3011342C (en) 2023-03-14
JP2021176302A (en) 2021-11-11
BR112018014349A2 (en) 2019-02-12
EP3402896B1 (en) 2021-03-31
US20230250476A1 (en) 2023-08-10
JP7232643B2 (en) 2023-03-03
WO2017123316A1 (en) 2017-07-20
JP7379418B2 (en) 2023-11-14

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