SG11201807465RA - Lipid biomarkers for the diagnosis of cancer - Google Patents

Lipid biomarkers for the diagnosis of cancer

Info

Publication number
SG11201807465RA
SG11201807465RA SG11201807465RA SG11201807465RA SG11201807465RA SG 11201807465R A SG11201807465R A SG 11201807465RA SG 11201807465R A SG11201807465R A SG 11201807465RA SG 11201807465R A SG11201807465R A SG 11201807465RA SG 11201807465R A SG11201807465R A SG 11201807465RA
Authority
SG
Singapore
Prior art keywords
singapore
cancer
international
pleural effusion
institute
Prior art date
Application number
SG11201807465RA
Inventor
Ying Swan Ho
Lian Yee Yip
Kiat Hon Tony Lim
Shao Weng Daniel Tan
Xulei Yang
Si Yong Yeo
Original Assignee
Agency Science Tech & Res
Singapore Health Serv Pte Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res, Singapore Health Serv Pte Ltd filed Critical Agency Science Tech & Res
Publication of SG11201807465RA publication Critical patent/SG11201807465RA/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/02—Triacylglycerols
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/04—Phospholipids, i.e. phosphoglycerides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/08—Sphingolipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization 11111111011110111010101111101011111011101111011100111011111001111101111011111 International Bureau 0.. .... .. (10) International Publication Number ...... ... (43) International Publication Date WO 2017/155473 Al 14 September 2017 (14.09.2017) WIP0 I PCT (51) International Patent Classification: (74) Agent: SPRUSON & FERGUSON (ASIA) PTE LTD; G01N 33/92 (2006.01) P.O. Box 1531, Robinson Road Post Office, Singapore (21) International Application Number: 903031 (SG). PCT/SG2017/050120 (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, (22) International Filing Date: AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, 10 March 2017 (10.03.2017) BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, (25) Filing Language: English DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, (26) Publication Language: English KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, (30) Priority Data: MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, 10201601873S 10 March 2016 (10.03.2016) SG NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, (71) Applicants: AGENCY FOR SCIENCE, TECHNO- TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, LOGY AND RESEARCH [SG/SG]; 1 Fusionopolis Way, ZA, ZM, ZW. #20-10 Connexis North Tower, Singapore 138632 (SG). SINGAPORE HEALTH SERVICES PTE LTD (84) Designated States (unless otherwise indicated, for every [SG/SG]; 31 Third Hospital Avenue, #03-03 Bowyer kind of regional protection available): ARIPO (BW, GH, Block C, Singapore 168753 (SG). GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, _ (72) Inventors: HO, Ying Swan; c/o Bioprocessing Techno- TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, logy Institute, 20 Biopolis Way, #06-01 Centros, Singapore DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, — _ 138668 (SG). YIP, Lian Yee; c/o Bioprocessing Techno- LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, logy Institute, 20 Biopolis Way, #06-01 Centros, Singapore SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, 138668 (SG). LIM, Kiat Hon Tony; c/o Singapore Gener- GW, KM, ML, MR, NE, SN, TD, TG). = al Hospital, Department of Pathology, 20 College Road, Academia, Level 7, Singapore 169856 (SG). TAN, Shao Declarations under Rule 4.17: Weng Daniel; c/o National Cancer Centre, 11 Hospital — of inventorship (Rule 4. 17(iv)) Drive, Singapore 169610 (SG). YANG, Xulei; c/o Institute of High Performance Computing, 1 Fusionopolis Way, Published: = #16-16 Connexis North Tower, Singapore 138632 (SG). — with international search report (Art. 21(3)) YEO, Si Yong; c/o Institute of High Performance Comput- ing, 1 Fusionopolis Way, #16-16 Connexis North Tower, Singapore 138632 (SG). = = = = = = = = = 1-1 M IN 7r 11 in 11 in ,—, (54) Title: LIPID BIOMARKERS FOR THE DIAGNOSIS OF CANCER C 1-1 (57) : The present disclosure provides lipid biomarkers from pleural effusion samples and use thereof in a method for de - el termining whether a patient suffering from pleural effusion has cancer, or in a method for treating cancer in a patient suffering from en. ) pleural effusion. Also disclosed herein is the use of lipid biomarkers from pleural effusion samples in a method for determining whether a patient suffering from pleural effusion has cancer with EGFR mutation, and in a method for treating cancer in a patient 5.- with EGFR mutation.
SG11201807465RA 2016-03-10 2017-03-10 Lipid biomarkers for the diagnosis of cancer SG11201807465RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SG10201601873S 2016-03-10
PCT/SG2017/050120 WO2017155473A1 (en) 2016-03-10 2017-03-10 Lipid biomarkers for the diagnosis of cancer

Publications (1)

Publication Number Publication Date
SG11201807465RA true SG11201807465RA (en) 2018-09-27

Family

ID=59789844

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201807465RA SG11201807465RA (en) 2016-03-10 2017-03-10 Lipid biomarkers for the diagnosis of cancer

Country Status (5)

Country Link
US (1) US20190302118A1 (en)
EP (1) EP3427066A4 (en)
CN (1) CN108885220A (en)
SG (1) SG11201807465RA (en)
WO (1) WO2017155473A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202006667VA (en) * 2018-01-22 2020-08-28 Univ Pardubice A method of diagnosing cancer based on lipidomic analysis of a body fluid
DK3575793T3 (en) * 2018-05-29 2023-10-09 Fons Jk Group A S A method of diagnosing cancer based on lipidomic analysis of a body fluid
KR102156216B1 (en) * 2019-03-05 2020-09-15 연세대학교 산학협력단 Lipid biomarker composition for diagnosing of gastric cancer and uses thereof
CN113138275B (en) * 2020-01-20 2022-05-06 中国科学院大连化学物理研究所 Serum lipid metabolite composition, kit and application
CN111537056A (en) * 2020-07-08 2020-08-14 浙江浙能天然气运行有限公司 Pipeline along-line third-party construction dynamic early warning method based on SVM and time-frequency domain characteristics
CN114544848B (en) * 2020-11-25 2023-04-28 中国科学院大连化学物理研究所 Serum lipid marker composition for diagnosing ovarian epithelial cancer, kit and application thereof
CN112798727B (en) * 2021-04-09 2021-07-06 宝枫生物科技（北京）有限公司 Biomarker F7 for diagnosing leukoencephalopathy and application thereof
CN114814023B (en) * 2022-04-24 2024-07-30 江苏省中医院 Application of lipid molecules as predictive markers of gastric cancer chemotherapeutic drug resistance
CN115762801B (en) * 2022-05-13 2024-01-23 中国医学科学院肿瘤医院 Peripheral blood lipid metabolism biomarker for predicting new adjuvant therapy response of breast cancer and application
CN117214276A (en) * 2023-09-12 2023-12-12 北京大学人民医院 Application of plasma lipid molecules in lung cancer diagnosis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2803865A1 (en) * 2010-06-23 2011-12-29 University Of Louisville Research Foundation, Inc. Methods for detecting cancer
GB201016139D0 (en) * 2010-09-24 2010-11-10 Univ Leuven Kath Cancer phosholipidome
CA2839530A1 (en) * 2011-06-16 2012-12-20 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Biomarker compositions and methods
US9404927B2 (en) * 2013-12-05 2016-08-02 The Translational Genomics Research Institute Systems and methods for diagnosing and treating cancer

Also Published As

Publication number Publication date
WO2017155473A1 (en) 2017-09-14
US20190302118A1 (en) 2019-10-03
EP3427066A1 (en) 2019-01-16
EP3427066A4 (en) 2020-02-19
CN108885220A (en) 2018-11-23

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