SG11201805480TA - Methods of using caspase inhibitors in treatment of liver disease - Google Patents
Methods of using caspase inhibitors in treatment of liver diseaseInfo
- Publication number
- SG11201805480TA SG11201805480TA SG11201805480TA SG11201805480TA SG11201805480TA SG 11201805480T A SG11201805480T A SG 11201805480TA SG 11201805480T A SG11201805480T A SG 11201805480TA SG 11201805480T A SG11201805480T A SG 11201805480TA SG 11201805480T A SG11201805480T A SG 11201805480TA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- pct
- treatment
- methods
- liver disease
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562274025P | 2015-12-31 | 2015-12-31 | |
PCT/US2016/069363 WO2017117478A1 (en) | 2015-12-31 | 2016-12-30 | Methods of using caspase inhibitors in treatment of liver disease |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201805480TA true SG11201805480TA (en) | 2018-07-30 |
Family
ID=57960814
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201805480TA SG11201805480TA (en) | 2015-12-31 | 2016-12-30 | Methods of using caspase inhibitors in treatment of liver disease |
Country Status (12)
Country | Link |
---|---|
US (1) | US20190022043A1 (es) |
EP (1) | EP3397251A1 (es) |
JP (1) | JP2019500397A (es) |
KR (1) | KR20180101418A (es) |
CN (1) | CN108697663A (es) |
AU (1) | AU2016381974A1 (es) |
BR (1) | BR112018013558A2 (es) |
CA (1) | CA3010286A1 (es) |
MX (1) | MX2018007964A (es) |
RU (1) | RU2018127752A (es) |
SG (1) | SG11201805480TA (es) |
WO (1) | WO2017117478A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3039283A1 (en) * | 2016-10-05 | 2018-04-12 | Novartis Ag | Combination compositions comprising fxr agonists for treating or preventing a fibrotic,cirrhotic disease or disorder |
EP3814327A1 (en) | 2018-06-29 | 2021-05-05 | Histogen, Inc. | (s)-3-(2-(4-(benzyl)-3-oxopiperazin-1-yl)acetamido)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid derivatives and related compounds as caspase inhibitors for treating cardiovascular diseases |
WO2023039276A1 (en) * | 2021-09-13 | 2023-03-16 | Curtails Llc | Use of ibat inhibitors and antimicrobials for the treatment of diseases |
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KR101125932B1 (ko) | 2006-12-06 | 2012-03-22 | 아이디유엔 파마슈티칼즈, 인코포레이티드 | (3s)-3-[n-(n'-(2-tert-부틸페닐)옥사밀)알라니닐]아미노-5-(2',3',5',6'-테트라플루오로페녹시)-4-옥소펜탄산의 결정 형태 |
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EP2739286A4 (en) | 2011-08-04 | 2015-06-03 | Lumena Pharmaceuticals Inc | INHIBITORS OF RECYCLING OF BILIARY ACID IN THE TREATMENT OF PANCREAS |
CN107375932B (zh) | 2011-10-28 | 2021-12-21 | 夏尔人类遗传性治疗公司 | 用于治疗小儿胆汁淤积性肝病的胆汁酸再循环抑制剂 |
EA029581B1 (ru) | 2011-10-28 | 2018-04-30 | ЛУМЕНА ФАРМАСЬЮТИКАЛС ЭлЭлСи | Применение ингибиторов рециркуляции желчных кислот для лечения холестатического заболевания печени или прурита |
WO2015175381A1 (en) * | 2014-05-12 | 2015-11-19 | Conatus Pharmaceuticals, Inc. | Treatment of the complications of chronic liver disease with caspase inhibitors |
-
2016
- 2016-12-30 KR KR1020187021242A patent/KR20180101418A/ko unknown
- 2016-12-30 MX MX2018007964A patent/MX2018007964A/es unknown
- 2016-12-30 BR BR112018013558A patent/BR112018013558A2/pt not_active Application Discontinuation
- 2016-12-30 CN CN201680082884.7A patent/CN108697663A/zh active Pending
- 2016-12-30 JP JP2018534746A patent/JP2019500397A/ja active Pending
- 2016-12-30 RU RU2018127752A patent/RU2018127752A/ru not_active Application Discontinuation
- 2016-12-30 AU AU2016381974A patent/AU2016381974A1/en not_active Abandoned
- 2016-12-30 WO PCT/US2016/069363 patent/WO2017117478A1/en active Application Filing
- 2016-12-30 EP EP16834072.7A patent/EP3397251A1/en not_active Withdrawn
- 2016-12-30 SG SG11201805480TA patent/SG11201805480TA/en unknown
- 2016-12-30 CA CA3010286A patent/CA3010286A1/en not_active Abandoned
- 2016-12-30 US US16/067,497 patent/US20190022043A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2019500397A (ja) | 2019-01-10 |
WO2017117478A1 (en) | 2017-07-06 |
CA3010286A1 (en) | 2017-07-06 |
RU2018127752A (ru) | 2020-01-31 |
EP3397251A1 (en) | 2018-11-07 |
BR112018013558A2 (pt) | 2018-12-04 |
KR20180101418A (ko) | 2018-09-12 |
MX2018007964A (es) | 2018-11-09 |
CN108697663A (zh) | 2018-10-23 |
US20190022043A1 (en) | 2019-01-24 |
AU2016381974A1 (en) | 2018-07-12 |
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