SG11201803760VA - Diamino pyridine derivatives - Google Patents
Diamino pyridine derivativesInfo
- Publication number
- SG11201803760VA SG11201803760VA SG11201803760VA SG11201803760VA SG11201803760VA SG 11201803760V A SG11201803760V A SG 11201803760VA SG 11201803760V A SG11201803760V A SG 11201803760VA SG 11201803760V A SG11201803760V A SG 11201803760VA SG 11201803760V A SG11201803760V A SG 11201803760VA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- basel
- pct
- novartis
- pyridine derivatives
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
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- A—HUMAN NECESSITIES
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Otolaryngology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15196542 | 2015-11-26 | ||
| PCT/IB2016/057105 WO2017089985A1 (en) | 2015-11-26 | 2016-11-24 | Diamino pyridine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201803760VA true SG11201803760VA (en) | 2018-06-28 |
Family
ID=54705130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201803760VA SG11201803760VA (en) | 2015-11-26 | 2016-11-24 | Diamino pyridine derivatives |
Country Status (35)
| Country | Link |
|---|---|
| US (3) | US10570096B2 (ru) |
| EP (2) | EP3380465B1 (ru) |
| JP (1) | JP6634157B2 (ru) |
| KR (1) | KR102097878B1 (ru) |
| CN (2) | CN108349937B (ru) |
| AU (1) | AU2016359438B2 (ru) |
| BR (1) | BR112018009540A2 (ru) |
| CA (1) | CA3005159A1 (ru) |
| CL (1) | CL2018001370A1 (ru) |
| CO (1) | CO2018005354A2 (ru) |
| CR (1) | CR20180285A (ru) |
| CU (1) | CU24506B1 (ru) |
| CY (1) | CY1123543T1 (ru) |
| DK (1) | DK3380465T3 (ru) |
| DO (1) | DOP2018000127A (ru) |
| EA (1) | EA035899B1 (ru) |
| EC (1) | ECSP18041731A (ru) |
| ES (2) | ES2916582T3 (ru) |
| HK (1) | HK1253530A1 (ru) |
| HR (1) | HRP20201662T1 (ru) |
| HU (1) | HUE052345T2 (ru) |
| IL (1) | IL259360B (ru) |
| LT (1) | LT3380465T (ru) |
| MX (1) | MX2018006495A (ru) |
| MY (1) | MY195905A (ru) |
| PE (1) | PE20181071A1 (ru) |
| PH (1) | PH12018501019A1 (ru) |
| PL (2) | PL3380465T3 (ru) |
| PT (2) | PT3757097T (ru) |
| RS (1) | RS60946B1 (ru) |
| RU (2) | RU2020124922A (ru) |
| SA (1) | SA518391657B1 (ru) |
| SG (1) | SG11201803760VA (ru) |
| SI (1) | SI3380465T1 (ru) |
| WO (1) | WO2017089985A1 (ru) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3380465T3 (da) * | 2015-11-26 | 2020-10-26 | Novartis Ag | Diaminopyridinderivativer |
| EP3908279B1 (en) | 2019-01-11 | 2024-08-28 | Novartis AG | Lta4h inhibitor for the treatment or prevention of hidradenitis suppurativa |
| TW202342048A (zh) | 2022-02-28 | 2023-11-01 | 瑞士商諾華公司 | 使用ｌｏｕ０６４治療化膿性汗腺炎之方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2514733A1 (en) | 2003-02-28 | 2004-09-16 | Transform Pharmaceuticals, Inc. | Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen |
| US7459562B2 (en) | 2004-04-23 | 2008-12-02 | Bristol-Myers Squibb Company | Monocyclic heterocycles as kinase inhibitors |
| EP2091918B1 (en) * | 2006-12-08 | 2014-08-27 | Irm Llc | Compounds and compositions as protein kinase inhibitors |
| CA2681015C (en) | 2007-03-16 | 2016-06-21 | The Scripps Research Institute | Inhibitors of focal adhesion kinase |
| EP2361902A4 (en) | 2008-11-21 | 2012-04-25 | Astellas Pharma Inc | 4,6-DIAMINONICOTINSÄUREAMIDVERBINDUNG |
| WO2010061971A1 (ja) | 2008-11-28 | 2010-06-03 | 興和株式会社 | ピリジン－３－カルボキシアミド誘導体 |
| PT2565193E (pt) | 2009-01-23 | 2014-06-05 | Rigel Pharmaceuticals Inc | Composições e métodos para a inibição da via jak |
| US8415381B2 (en) * | 2009-07-30 | 2013-04-09 | Novartis Ag | Heteroaryl compounds and their uses |
| US9102625B2 (en) | 2010-11-01 | 2015-08-11 | Portola Pharmaceuticals, Inc. | Nicotinamides as JAK kinase modulators |
| US9198911B2 (en) | 2010-11-02 | 2015-12-01 | The Trustees Of Columbia University In The City Of New York | Methods for treating hair loss disorders |
| CA2883534A1 (en) | 2012-10-19 | 2014-04-24 | F. Hoffmann-La Roche Ag | Inhibitors of syk |
| WO2014074675A1 (en) * | 2012-11-08 | 2014-05-15 | Bristol-Myers Squibb Company | Heteroaryl substituted pyridyl compounds useful as kinase modulators |
| SG11201503396UA (en) * | 2012-11-08 | 2015-05-28 | Bristol Myers Squibb Co | ALKYL-AMIDE-SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFNα RESPONSES |
| ES2914793T3 (es) | 2012-11-08 | 2022-06-16 | Bristol Myers Squibb Co | Compuestos heterocíclicos sustituidos con amida, útiles como moduladores de la respuesta de IL-12, IL-23 y/o IFN-alfa |
| US20140343034A1 (en) | 2013-04-25 | 2014-11-20 | Japan Tobacco Inc. | Skin barrier function improving agent |
| WO2014181287A1 (en) | 2013-05-09 | 2014-11-13 | Piramal Enterprises Limited | Heterocyclyl compounds and uses thereof |
| WO2014203132A1 (en) | 2013-06-19 | 2014-12-24 | Olema Pharmaceuticals, Inc. | Substituted benzopyran compounds, compositions and uses thereof |
| JP2015014960A (ja) | 2013-07-05 | 2015-01-22 | ソニー株式会社 | 情報処理装置、および記憶媒体 |
| US20150118229A1 (en) | 2013-10-24 | 2015-04-30 | Abbvie Inc. | Jak1 selective inhibitor and uses thereof |
| CA2969590A1 (en) | 2014-12-03 | 2016-06-09 | Rxi Pharmaceuticals Corporation | Methods for the treatment of alopecia areata utilizing gene modulation approaches |
| DK3380465T3 (da) * | 2015-11-26 | 2020-10-26 | Novartis Ag | Diaminopyridinderivativer |
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2016
- 2016-11-24 DK DK16805218.1T patent/DK3380465T3/da active
- 2016-11-24 CN CN201680065351.8A patent/CN108349937B/zh active Active
- 2016-11-24 CN CN202110135667.2A patent/CN112851578A/zh not_active Withdrawn
- 2016-11-24 US US15/778,783 patent/US10570096B2/en active Active
- 2016-11-24 BR BR112018009540A patent/BR112018009540A2/pt not_active Application Discontinuation
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- 2016-11-24 SG SG11201803760VA patent/SG11201803760VA/en unknown
- 2016-11-24 EP EP16805218.1A patent/EP3380465B1/en active Active
- 2016-11-24 MY MYPI2018701770A patent/MY195905A/en unknown
- 2016-11-24 ES ES20185507T patent/ES2916582T3/es active Active
- 2016-11-24 CA CA3005159A patent/CA3005159A1/en not_active Abandoned
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- 2016-11-24 PT PT168052181T patent/PT3380465T/pt unknown
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- 2016-11-24 RU RU2020124922A patent/RU2020124922A/ru unknown
- 2016-11-24 RU RU2018122953A patent/RU2730007C2/ru active
- 2016-11-24 WO PCT/IB2016/057105 patent/WO2017089985A1/en active Application Filing
- 2016-11-24 RS RS20201234A patent/RS60946B1/sr unknown
- 2016-11-24 PL PL16805218T patent/PL3380465T3/pl unknown
- 2016-11-24 EA EA201891258A patent/EA035899B1/ru not_active IP Right Cessation
- 2016-11-24 LT LTEP16805218.1T patent/LT3380465T/lt unknown
- 2016-11-24 HU HUE16805218A patent/HUE052345T2/hu unknown
- 2016-11-24 KR KR1020187014470A patent/KR102097878B1/ko active IP Right Grant
- 2016-11-24 JP JP2018527091A patent/JP6634157B2/ja not_active Expired - Fee Related
- 2016-11-24 PL PL20185507.9T patent/PL3757097T3/pl unknown
- 2016-11-24 MX MX2018006495A patent/MX2018006495A/es unknown
- 2016-11-24 CU CU2018000044A patent/CU24506B1/es unknown
- 2016-11-24 SI SI201630959T patent/SI3380465T1/sl unknown
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2018
- 2018-05-14 IL IL259360A patent/IL259360B/en active IP Right Grant
- 2018-05-15 PH PH12018501019A patent/PH12018501019A1/en unknown
- 2018-05-21 DO DO2018000127A patent/DOP2018000127A/es unknown
- 2018-05-22 CO CONC2018/0005354A patent/CO2018005354A2/es unknown
- 2018-05-22 CL CL2018001370A patent/CL2018001370A1/es unknown
- 2018-05-23 SA SA518391657A patent/SA518391657B1/ar unknown
- 2018-05-31 EC ECIEPI201841731A patent/ECSP18041731A/es unknown
- 2018-10-05 HK HK18112730.0A patent/HK1253530A1/zh unknown
-
2020
- 2020-01-08 US US16/737,366 patent/US11274080B2/en active Active
- 2020-10-14 HR HRP20201662TT patent/HRP20201662T1/hr unknown
- 2020-11-03 CY CY20201101039T patent/CY1123543T1/el unknown
-
2022
- 2022-02-22 US US17/677,538 patent/US20220177432A1/en not_active Abandoned
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