SG11201803605YA - [1,2,4]TRIAZOLO[1,5-a]PYRIMIDIN-7-YL COMPOUND - Google Patents
[1,2,4]TRIAZOLO[1,5-a]PYRIMIDIN-7-YL COMPOUNDInfo
- Publication number
- SG11201803605YA SG11201803605YA SG11201803605YA SG11201803605YA SG11201803605YA SG 11201803605Y A SG11201803605Y A SG 11201803605YA SG 11201803605Y A SG11201803605Y A SG 11201803605YA SG 11201803605Y A SG11201803605Y A SG 11201803605YA SG 11201803605Y A SG11201803605Y A SG 11201803605YA
- Authority
- SG
- Singapore
- Prior art keywords
- triazolo
- pyrimidin
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP15192661 | 2015-11-02 | ||
EP15192966 | 2015-11-04 | ||
PCT/EP2016/076420 WO2017076900A1 (en) | 2015-11-02 | 2016-11-02 | [1,2,4]TRIAZOLO[1,5-a]PYRIMIDIN-7-YL COMPOUND |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201803605YA true SG11201803605YA (en) | 2018-05-30 |
Family
ID=57256277
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201803605YA SG11201803605YA (en) | 2015-11-02 | 2016-11-02 | [1,2,4]TRIAZOLO[1,5-a]PYRIMIDIN-7-YL COMPOUND |
Country Status (20)
Country | Link |
---|---|
US (1) | US10947239B2 (es) |
EP (1) | EP3371188B1 (es) |
JP (1) | JP6872541B2 (es) |
KR (1) | KR20180075630A (es) |
CN (1) | CN108349979B (es) |
AU (1) | AU2016348549B2 (es) |
BR (1) | BR112018008431A2 (es) |
CA (1) | CA3001768C (es) |
CO (1) | CO2018005163A2 (es) |
EA (1) | EA036851B1 (es) |
ES (1) | ES2765738T3 (es) |
HK (1) | HK1256751A1 (es) |
IL (1) | IL259004B (es) |
MX (1) | MX2018005342A (es) |
MY (1) | MY194700A (es) |
PH (1) | PH12018500944A1 (es) |
SG (1) | SG11201803605YA (es) |
UA (1) | UA122423C2 (es) |
WO (1) | WO2017076900A1 (es) |
ZA (1) | ZA201802842B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG11201701315VA (en) | 2014-08-28 | 2017-03-30 | Asceneuron Sa | Glycosidase inhibitors |
CA3001768C (en) | 2015-11-02 | 2022-12-13 | Janssen Pharmaceutica Nv | [1,2,4]triazolo[1,5-a]pyrimidin-7-yl compound |
US11261183B2 (en) | 2016-02-25 | 2022-03-01 | Asceneuron Sa | Sulfoximine glycosidase inhibitors |
CA3012624A1 (en) | 2016-02-25 | 2017-08-31 | Asceneuron S.A. | Glycosidase inhibitors |
KR20180132060A (ko) | 2016-02-25 | 2018-12-11 | 아셰뉴론 에스아 | 피페라진 유도체의 산 부가 염 |
CN108884077A (zh) | 2016-02-25 | 2018-11-23 | 阿森纽荣股份公司 | 糖苷酶抑制剂 |
EA039102B1 (ru) | 2016-11-02 | 2021-12-03 | Янссен Фармацевтика Нв | Соединения [1,2,4]триазоло[1,5-a]пиримидина в качестве ингибиторов pde2 |
AU2017353310B2 (en) | 2016-11-02 | 2021-08-12 | Janssen Pharmaceutica Nv | [1,2,4]triazolo[1,5-a]pyrimidine derivatives as PDE2 inhibitors |
MA46690A (fr) | 2016-11-02 | 2019-09-11 | Janssen Pharmaceutica Nv | Composés de [1,2,4]triazolo [1,5-a]pyrimidine en tant qu'inhibiteurs de pde2 |
WO2018109198A1 (en) | 2016-12-16 | 2018-06-21 | Janssen Pharmaceutica Nv | Bicyclic oga inhibitor compounds |
EP3672959A1 (en) | 2017-08-24 | 2020-07-01 | Asceneuron SA | Linear glycosidase inhibitors |
US11731972B2 (en) | 2018-08-22 | 2023-08-22 | Asceneuron Sa | Spiro compounds as glycosidase inhibitors |
WO2020039028A1 (en) | 2018-08-22 | 2020-02-27 | Asceneuron S. A. | Tetrahydro-benzoazepine glycosidase inhibitors |
CN114605416B (zh) * | 2020-12-08 | 2023-12-01 | 奥锐特药业(天津)有限公司 | 阿卡替尼晶型i的制备方法 |
Family Cites Families (40)
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JPH06509069A (ja) | 1991-06-27 | 1994-10-13 | バージニア・コモンウェルス・ユニバーシティ | シグマレセプターリガンドおよびその用途 |
CA2319198C (en) | 1998-01-27 | 2011-02-22 | Aventis Pharmaceuticals Products Inc. | Substituted oxoazaheterocyclyl factor xa inhibitors |
US6194410B1 (en) | 1998-03-11 | 2001-02-27 | Hoffman-La Roche Inc. | Pyrazolopyrimidine and pyrazolines and process for preparation thereof |
US20040014744A1 (en) | 2002-04-05 | 2004-01-22 | Fortuna Haviv | Substituted pyridines having antiangiogenic activity |
PL376149A1 (en) | 2002-10-03 | 2005-12-27 | Vertex Pharmaceuticals Incorporated | Piperazine and piperidine derivatives for treatment of neurological diseases |
US20070275961A1 (en) | 2003-06-04 | 2007-11-29 | Vernalis (Cambridge) Limited. | Triazolo ' 1, 5-A ! Pyrimidines and Their Use in Medicine |
ES2317031T3 (es) * | 2003-07-16 | 2009-04-16 | Janssen Pharmaceutica Nv | Derivados de triazolopirimidina como inhibidores de la glucogeno-sintasa-quinasa 3. |
RU2329261C2 (ru) | 2003-12-29 | 2008-07-20 | Баниу Фармасьютикал Ко., Лтд. | Новое 2-гетероарил-замещенное производное бензимидазола |
EP1814551A2 (en) | 2004-09-20 | 2007-08-08 | Xenon Pharmaceuticals Inc. | Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase |
WO2006034440A2 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors |
JP2008516973A (ja) | 2004-10-15 | 2008-05-22 | タケダ サン ディエゴ インコーポレイテッド | キナーゼ阻害剤 |
US7507842B2 (en) | 2005-08-12 | 2009-03-24 | Radiorx, Inc. | Cyclic nitro compounds, pharmaceutical compositions thereof and uses thereof |
WO2007113136A1 (de) * | 2006-03-30 | 2007-10-11 | Basf Aktiengesellschaft | Verwendung von substituierten riazolopyrimidinen zur bekämpfung von phyto pathogenen schadpilzen |
JP2007332061A (ja) | 2006-06-14 | 2007-12-27 | Nippon Kayaku Co Ltd | 新規ピラゾロ[1,5−a]ピリミジン誘導体及びその用途 |
US8153803B2 (en) | 2006-07-18 | 2012-04-10 | The General Hospital Corporation | Compositions and methods for modulating sirtuin activity |
WO2008048914A1 (en) | 2006-10-17 | 2008-04-24 | Boehringer Ingelheim International Gmbh | Polycyclic compounds which modulate the cb2 receptor |
US8138168B1 (en) | 2007-09-26 | 2012-03-20 | Takeda Pharmaceutical Company Limited | Renin inhibitors |
GB0719803D0 (en) | 2007-10-10 | 2007-11-21 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
ES2553610T3 (es) * | 2010-12-14 | 2015-12-10 | Electrophoretics Limited | Inhibidores de la caseína cinasa 1 delta (CK1delta) |
JP5543039B2 (ja) * | 2011-02-23 | 2014-07-09 | ファイザー・インク | 神経障害治療のためのイミダゾ[5,1−f][1,2,4]トリアジン |
BR112013033375B1 (pt) * | 2011-06-27 | 2022-05-10 | Janssen Pharmaceutica N.V | Derivados de 1-aril-4-metil-[1,2,4]triazolo[4,3-a]quinoxa-lina, seu uso, composição farmacêutica que os compreende, processo de preparação dos mesmos, solução estéril e composto intermediário |
JP2014527981A (ja) | 2011-09-23 | 2014-10-23 | アドヴィナス・セラピューティックス・リミテッド | アミド化合物、組成物およびその用途 |
US9034882B2 (en) | 2012-03-05 | 2015-05-19 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
US8946415B2 (en) | 2012-03-09 | 2015-02-03 | Lexicon Pharmaceuticals, Inc. | Pyrazolo[1,5-a]pyrimidine-based compounds, compositions comprising them, and methods of their use |
KR102313353B1 (ko) * | 2013-07-29 | 2021-10-18 | 삼성전자주식회사 | 캐릭터 입력 방법 및 디스플레이 장치 |
CA2936886A1 (en) | 2014-02-27 | 2015-08-03 | Merck Patent Gmbh | Heterocyclic compounds as nav channel inhibitors and uses thereof |
PT3119772T (pt) * | 2014-03-19 | 2019-09-05 | Boehringer Ingelheim Int | Inibidores de syk heteroarilo |
DK3597649T3 (da) * | 2014-04-23 | 2022-01-10 | Dart Neuroscience Llc | Sammensætninger indeholdende substituerede [1,2,4]triazolo[1,5-a]pyrimidin-7-yl-forbindelser som pde2-inhibitorer |
CN105566321B (zh) | 2014-10-29 | 2020-04-21 | 广东东阳光药业有限公司 | 杂芳化合物及其在药物中的应用 |
WO2016107602A1 (zh) | 2015-01-01 | 2016-07-07 | 成都贝斯凯瑞生物科技有限公司 | 一类取代氮杂环衍生物及其应用 |
WO2016145614A1 (en) | 2015-03-17 | 2016-09-22 | Merck Sharp & Dohme Corp. | Triazolyl pyrimidinone compounds as pde2 inhibitors |
WO2017000277A1 (en) | 2015-07-01 | 2017-01-05 | Merck Sharp & Dohme Corp. | Substituted triazolo bicycliccompounds as pde2 inhibitors |
WO2017000276A1 (en) | 2015-07-01 | 2017-01-05 | Merck Sharp & Dohme Corp. | Bicyclic heterocyclic compounds as pde2 inhibitors |
US20180305334A1 (en) | 2015-10-14 | 2018-10-25 | Aquinnah Pharmaceuticals, Inc. | Compounds, compositions and methods of use against stress granules |
CA3001768C (en) | 2015-11-02 | 2022-12-13 | Janssen Pharmaceutica Nv | [1,2,4]triazolo[1,5-a]pyrimidin-7-yl compound |
WO2017157882A1 (en) | 2016-03-14 | 2017-09-21 | Université Catholique de Louvain | Serine biosynthetic pathway inhibitors |
EA039102B1 (ru) | 2016-11-02 | 2021-12-03 | Янссен Фармацевтика Нв | Соединения [1,2,4]триазоло[1,5-a]пиримидина в качестве ингибиторов pde2 |
AU2017353310B2 (en) | 2016-11-02 | 2021-08-12 | Janssen Pharmaceutica Nv | [1,2,4]triazolo[1,5-a]pyrimidine derivatives as PDE2 inhibitors |
MA46690A (fr) | 2016-11-02 | 2019-09-11 | Janssen Pharmaceutica Nv | Composés de [1,2,4]triazolo [1,5-a]pyrimidine en tant qu'inhibiteurs de pde2 |
WO2018109198A1 (en) | 2016-12-16 | 2018-06-21 | Janssen Pharmaceutica Nv | Bicyclic oga inhibitor compounds |
-
2016
- 2016-11-02 CA CA3001768A patent/CA3001768C/en active Active
- 2016-11-02 BR BR112018008431-0A patent/BR112018008431A2/pt not_active Application Discontinuation
- 2016-11-02 SG SG11201803605YA patent/SG11201803605YA/en unknown
- 2016-11-02 MY MYPI2018000611A patent/MY194700A/en unknown
- 2016-11-02 KR KR1020187015072A patent/KR20180075630A/ko not_active Application Discontinuation
- 2016-11-02 WO PCT/EP2016/076420 patent/WO2017076900A1/en active Application Filing
- 2016-11-02 AU AU2016348549A patent/AU2016348549B2/en not_active Ceased
- 2016-11-02 UA UAA201806063A patent/UA122423C2/uk unknown
- 2016-11-02 US US15/772,859 patent/US10947239B2/en active Active
- 2016-11-02 EA EA201891067A patent/EA036851B1/ru unknown
- 2016-11-02 JP JP2018521971A patent/JP6872541B2/ja active Active
- 2016-11-02 MX MX2018005342A patent/MX2018005342A/es active IP Right Grant
- 2016-11-02 CN CN201680063119.0A patent/CN108349979B/zh active Active
- 2016-11-02 ES ES16793800T patent/ES2765738T3/es active Active
- 2016-11-02 EP EP16793800.0A patent/EP3371188B1/en active Active
-
2018
- 2018-04-29 IL IL259004A patent/IL259004B/en active IP Right Grant
- 2018-04-30 ZA ZA2018/02842A patent/ZA201802842B/en unknown
- 2018-05-02 PH PH12018500944A patent/PH12018500944A1/en unknown
- 2018-05-16 CO CONC2018/0005163A patent/CO2018005163A2/es unknown
- 2018-12-11 HK HK18115831.1A patent/HK1256751A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
PH12018500944B1 (en) | 2018-11-19 |
JP2018535968A (ja) | 2018-12-06 |
MY194700A (en) | 2022-12-15 |
UA122423C2 (uk) | 2020-11-10 |
EP3371188B1 (en) | 2019-10-23 |
JP6872541B2 (ja) | 2021-05-19 |
KR20180075630A (ko) | 2018-07-04 |
AU2016348549A1 (en) | 2018-04-26 |
ES2765738T3 (es) | 2020-06-10 |
ZA201802842B (en) | 2021-04-28 |
BR112018008431A2 (pt) | 2018-11-06 |
US10947239B2 (en) | 2021-03-16 |
AU2016348549B2 (en) | 2020-07-23 |
PH12018500944A1 (en) | 2018-11-19 |
IL259004A (en) | 2018-06-28 |
WO2017076900A1 (en) | 2017-05-11 |
EA036851B1 (ru) | 2020-12-28 |
CA3001768A1 (en) | 2017-05-11 |
US20180327408A1 (en) | 2018-11-15 |
EP3371188A1 (en) | 2018-09-12 |
EA201891067A1 (ru) | 2018-10-31 |
MX2018005342A (es) | 2018-08-15 |
CO2018005163A2 (es) | 2018-06-20 |
CN108349979A (zh) | 2018-07-31 |
HK1256751A1 (zh) | 2019-10-04 |
IL259004B (en) | 2021-06-30 |
CN108349979B (zh) | 2021-04-09 |
CA3001768C (en) | 2022-12-13 |
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