SG11201706332RA - Methods and systems for biological instrument calibration - Google Patents

Methods and systems for biological instrument calibration

Info

Publication number
SG11201706332RA
SG11201706332RA SG11201706332RA SG11201706332RA SG11201706332RA SG 11201706332R A SG11201706332R A SG 11201706332RA SG 11201706332R A SG11201706332R A SG 11201706332RA SG 11201706332R A SG11201706332R A SG 11201706332RA SG 11201706332R A SG11201706332R A SG 11201706332RA
Authority
SG
Singapore
Prior art keywords
systems
methods
instrument calibration
biological instrument
biological
Prior art date
Application number
SG11201706332RA
Other languages
English (en)
Inventor
Yong Chu
Jeffrey Marks
Jacob Freudenthal
Thomas Wessel
David Woo
Original Assignee
Life Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Technologies Corp filed Critical Life Technologies Corp
Publication of SG11201706332RA publication Critical patent/SG11201706332RA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6851Quantitative amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274Calibration, base line adjustment, drift correction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6463Optics
    • G01N2021/6471Special filters, filter wheel
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274Calibration, base line adjustment, drift correction
    • G01N21/278Constitution of standards
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/12Circuits of general importance; Signal processing
    • G01N2201/127Calibration; base line adjustment; drift compensation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/12Circuits of general importance; Signal processing
    • G01N2201/13Standards, constitution
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/916Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
    • G01N2333/922Ribonucleases (RNAses); Deoxyribonucleases (DNAses)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Theoretical Computer Science (AREA)
  • Mathematical Physics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SG11201706332RA 2015-02-06 2016-02-05 Methods and systems for biological instrument calibration SG11201706332RA (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201562113058P 2015-02-06 2015-02-06
US201562113118P 2015-02-06 2015-02-06
US201562113077P 2015-02-06 2015-02-06
US201562113183P 2015-02-06 2015-02-06
US201562112964P 2015-02-06 2015-02-06
PCT/US2016/016882 WO2016127124A2 (en) 2015-02-06 2016-02-05 Methods and systems for biological instrument calibration

Publications (1)

Publication Number Publication Date
SG11201706332RA true SG11201706332RA (en) 2017-09-28

Family

ID=55361999

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201706332RA SG11201706332RA (en) 2015-02-06 2016-02-05 Methods and systems for biological instrument calibration

Country Status (9)

Country Link
US (2) US10012590B2 (ja)
EP (1) EP3254079B1 (ja)
JP (2) JP6736566B2 (ja)
KR (1) KR102360726B1 (ja)
CN (1) CN107407632B (ja)
BR (1) BR112017016814B1 (ja)
RU (1) RU2716171C2 (ja)
SG (1) SG11201706332RA (ja)
WO (1) WO2016127124A2 (ja)

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EP3360970B1 (en) * 2017-02-10 2019-10-30 Roche Diagnostics GmbH A method for reducing quantification errors caused by an optical artefact in digital polymerase chain reaction
GB2571743A (en) * 2018-03-07 2019-09-11 Pop Bio Ltd A method of capturing image data of a luminescent sample and apparatus for the same
EP3803339A1 (en) * 2018-06-08 2021-04-14 Perkinelmer Health Sciences Inc. Calibration of multispectral analysis systems
KR102261902B1 (ko) * 2018-09-28 2021-06-08 주식회사 바이오메듀스 실시간 중합효소 연쇄반응 형광 검출 장치
GB2581363A (en) * 2019-02-14 2020-08-19 Univ Exeter Test apparatus
KR102264336B1 (ko) * 2019-05-20 2021-06-14 정유한 광학식 체외진단기기와 이를 이용한 체외진단 방법
CN110208198A (zh) * 2019-07-05 2019-09-06 南京嘉恒仪器设备有限公司 一种微生物鉴定与药敏分析系统校准装置
CN110849827B (zh) * 2019-12-06 2021-02-09 中国科学院长春光学精密机械与物理研究所 中阶梯光谱仪的光谱定标方法、装置、设备及存储介质
CN111269971B (zh) * 2020-02-17 2023-06-20 上海科源电子科技有限公司 自动标定聚合酶链式反应荧光信号的方法
CN111751339B (zh) * 2020-06-23 2023-03-28 成都博奥晶芯生物科技有限公司 一种微阵列芯片激光共焦扫描仪的校准方法
CN111830013B (zh) * 2020-06-28 2021-03-16 杭州棒糖网络科技有限公司 一种提高激素浓度测量设备的测量准确性的方法
CN111926064B (zh) * 2020-07-01 2024-01-26 重庆京因生物科技有限责任公司 基于poct的荧光定量pcr仪校准方法及pcr仪
CN111870225A (zh) * 2020-08-04 2020-11-03 中国科学技术大学 一种用于荧光标定的标准模板制作方法
CN112600880B (zh) * 2020-12-01 2022-06-07 南京溯远基因科技有限公司 一种基于基因数据采集与分析的边缘计算装置及方法
CN113791041B (zh) * 2021-08-05 2024-05-10 北京农业信息技术研究中心 土壤重金属检测设备的自适应校正方法及检测设备
WO2023043851A1 (en) * 2021-09-14 2023-03-23 Combinati, Inc. Systems and methods for polymerase chain reaction quantification
CN113720825B (zh) * 2021-11-04 2022-02-08 四川丹诺迪科技有限公司 光学即时检测器及检测方法和应用
CN114414542B (zh) * 2021-12-20 2024-01-12 成都瀚辰光翼科技有限责任公司 用于基因检测的荧光信号检测方法、装置、介质及设备
WO2023171463A1 (ja) * 2022-03-10 2023-09-14 ソニーグループ株式会社 情報処理装置及び情報処理システム
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Also Published As

Publication number Publication date
BR112017016814A2 (pt) 2018-04-03
KR20170134359A (ko) 2017-12-06
US20180292320A1 (en) 2018-10-11
CN107407632B (zh) 2020-08-25
WO2016127124A2 (en) 2016-08-11
JP2020095051A (ja) 2020-06-18
EP3254079A2 (en) 2017-12-13
CN107407632A (zh) 2017-11-28
RU2017131046A3 (ja) 2019-07-17
JP2018507405A (ja) 2018-03-15
US10012590B2 (en) 2018-07-03
JP6736566B2 (ja) 2020-08-05
WO2016127124A3 (en) 2016-09-29
US20160231246A1 (en) 2016-08-11
BR112017016814B1 (pt) 2021-04-20
RU2716171C2 (ru) 2020-03-06
RU2017131046A (ru) 2019-03-06
EP3254079B1 (en) 2021-05-19
KR102360726B1 (ko) 2022-02-10

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