SG11201703748PA - Nucleic acid compounds for binding growth differentiation factor 11 - Google Patents

Nucleic acid compounds for binding growth differentiation factor 11

Info

Publication number
SG11201703748PA
SG11201703748PA SG11201703748PA SG11201703748PA SG11201703748PA SG 11201703748P A SG11201703748P A SG 11201703748PA SG 11201703748P A SG11201703748P A SG 11201703748PA SG 11201703748P A SG11201703748P A SG 11201703748PA SG 11201703748P A SG11201703748P A SG 11201703748PA
Authority
SG
Singapore
Prior art keywords
nucleic acid
acid compounds
differentiation factor
growth differentiation
binding growth
Prior art date
Application number
SG11201703748PA
Other languages
English (en)
Inventor
Urs Ochsner
Louis Green
Dom Zichi
Nebojsa Janjic
Original Assignee
Somalogic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Somalogic Inc filed Critical Somalogic Inc
Publication of SG11201703748PA publication Critical patent/SG11201703748PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/16Aptamers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors
    • G01N2333/495Transforming growth factor [TGF]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11201703748PA 2014-11-24 2015-11-23 Nucleic acid compounds for binding growth differentiation factor 11 SG11201703748PA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462083592P 2014-11-24 2014-11-24
US201562113864P 2015-02-09 2015-02-09
PCT/US2015/062155 WO2016085860A1 (en) 2014-11-24 2015-11-23 Nucleic acid compounds for binding growth differentiation factor 11

Publications (1)

Publication Number Publication Date
SG11201703748PA true SG11201703748PA (en) 2017-06-29

Family

ID=55069068

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201703748PA SG11201703748PA (en) 2014-11-24 2015-11-23 Nucleic acid compounds for binding growth differentiation factor 11

Country Status (14)

Country Link
US (3) US10808251B2 (zh)
EP (1) EP3224361B1 (zh)
JP (2) JP6768651B2 (zh)
KR (1) KR102558890B1 (zh)
CN (1) CN107075518B (zh)
AU (1) AU2015353767B2 (zh)
BR (1) BR112017008476B1 (zh)
CA (1) CA2966925C (zh)
IL (1) IL251934B (zh)
MX (1) MX2017006521A (zh)
RU (1) RU2708170C2 (zh)
SG (1) SG11201703748PA (zh)
TW (1) TWI695068B (zh)
WO (1) WO2016085860A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201811199QA (en) * 2016-07-01 2019-01-30 Somalogic Inc Oligonucleotides comprising modified nucleosides

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE160821T1 (de) 1990-06-11 1997-12-15 Nexstar Pharmaceuticals Inc Nukleinsäureliganden
US6001577A (en) 1998-06-08 1999-12-14 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex
US5763177A (en) 1990-06-11 1998-06-09 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex
US5705337A (en) 1990-06-11 1998-01-06 Nexstar Pharmaceuticals, Inc. Systematic evolution of ligands by exponential enrichment: chemi-SELEX
US5580737A (en) 1990-06-11 1996-12-03 Nexstar Pharmaceuticals, Inc. High-affinity nucleic acid ligands that discriminate between theophylline and caffeine
US5660985A (en) 1990-06-11 1997-08-26 Nexstar Pharmaceuticals, Inc. High affinity nucleic acid ligands containing modified nucleotides
US5719273A (en) 1993-06-14 1998-02-17 Nexstar Pharmaceuticals, Inc. Palladium catalyzed nucleoside modifications methods using nucleophiles and carbon monoxide
US6458539B1 (en) 1993-09-17 2002-10-01 Somalogic, Inc. Photoselection of nucleic acid ligands
US5945527A (en) 1996-05-30 1999-08-31 Nexstar Pharmaceuticals, Inc. Palladium catalyzed nucleoside modification methods using nucleophiles and carbon monoxide
WO1999006559A1 (en) 1997-08-01 1999-02-11 The Johns Hopkins University School Of Medicine Methods to identify growth differentiation factor (gdf) receptors
US6242246B1 (en) 1997-12-15 2001-06-05 Somalogic, Inc. Nucleic acid ligand diagnostic Biochip
US6376190B1 (en) 2000-09-22 2002-04-23 Somalogic, Inc. Modified SELEX processes without purified protein
EA015916B1 (ru) * 2006-09-05 2011-12-30 Эли Лилли Энд Компани Моноклональные антитела к миостатину и их применения
US7947447B2 (en) 2007-01-16 2011-05-24 Somalogic, Inc. Method for generating aptamers with improved off-rates
US7855054B2 (en) 2007-01-16 2010-12-21 Somalogic, Inc. Multiplexed analyses of test samples
CN101802225B (zh) 2007-07-17 2013-10-30 私募蛋白质体公司 检测样品的多元分析
PE20091163A1 (es) 2007-11-01 2009-08-09 Wyeth Corp Anticuerpos para gdf8
JO3340B1 (ar) 2010-05-26 2019-03-13 Regeneron Pharma مضادات حيوية لـعامل تمايز النمو 8 البشري
NZ608206A (en) 2010-08-16 2015-02-27 Amgen Inc Antibodies that bind myostatin, compositions and methods
EP2828289B1 (en) 2012-03-19 2020-02-26 The Brigham and Women's Hospital, Inc. Growth differentiation factor (gdf) 11 for treatment of age-related cardiovascular condition
AU2013334659B2 (en) * 2012-10-24 2019-07-11 Celgene Corporation Biomarker for use in treating anemia
JP2016518357A (ja) * 2013-04-08 2016-06-23 プレジデント アンド フェローズ オブ ハーバード カレッジ 骨格筋幹細胞を若返らせる方法および組成物
AU2014326975B2 (en) 2013-09-24 2020-05-07 Somalogic Operating Co., Inc. Multiaptamer target detection

Also Published As

Publication number Publication date
BR112017008476B1 (pt) 2024-03-12
JP2021000118A (ja) 2021-01-07
US20190024087A1 (en) 2019-01-24
MX2017006521A (es) 2017-08-09
RU2017121801A3 (zh) 2019-05-27
US20210130829A1 (en) 2021-05-06
NZ731836A (en) 2023-11-24
EP3224361B1 (en) 2019-06-19
BR112017008476A2 (pt) 2018-01-09
CA2966925A1 (en) 2016-06-02
CN107075518A (zh) 2017-08-18
IL251934B (en) 2021-07-29
US10808251B2 (en) 2020-10-20
JP6858911B2 (ja) 2021-04-14
IL251934A0 (en) 2017-06-29
AU2015353767A1 (en) 2017-05-25
BR112017008476A8 (pt) 2022-10-18
CA2966925C (en) 2023-08-29
JP6768651B2 (ja) 2020-10-14
RU2708170C2 (ru) 2019-12-04
EP3224361A1 (en) 2017-10-04
US20230193287A1 (en) 2023-06-22
CN107075518B (zh) 2021-03-09
RU2017121801A (ru) 2018-12-26
TWI695068B (zh) 2020-06-01
TW201638335A (zh) 2016-11-01
JP2017536118A (ja) 2017-12-07
KR102558890B1 (ko) 2023-07-21
WO2016085860A1 (en) 2016-06-02
AU2015353767B2 (en) 2021-09-09
KR20170084068A (ko) 2017-07-19
US11535852B2 (en) 2022-12-27

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