SG11201703307WA - Therapy for inhibition of single-stranded rna virus replication - Google Patents

Therapy for inhibition of single-stranded rna virus replication

Info

Publication number
SG11201703307WA
SG11201703307WA SG11201703307WA SG11201703307WA SG11201703307WA SG 11201703307W A SG11201703307W A SG 11201703307WA SG 11201703307W A SG11201703307W A SG 11201703307WA SG 11201703307W A SG11201703307W A SG 11201703307WA SG 11201703307W A SG11201703307W A SG 11201703307WA
Authority
SG
Singapore
Prior art keywords
inhibition
therapy
stranded rna
rna virus
virus replication
Prior art date
Application number
SG11201703307WA
Other languages
English (en)
Inventor
Reza Fathi
Dror Ben-Asher
Guy Goldberg
Original Assignee
Redhill Biopharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Redhill Biopharma Ltd filed Critical Redhill Biopharma Ltd
Publication of SG11201703307WA publication Critical patent/SG11201703307WA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11201703307WA 2014-10-24 2015-10-23 Therapy for inhibition of single-stranded rna virus replication SG11201703307WA (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201462068465P 2014-10-24 2014-10-24
US201462068487P 2014-10-24 2014-10-24
US201462068469P 2014-10-24 2014-10-24
US201462068477P 2014-10-24 2014-10-24
US201462068492P 2014-10-24 2014-10-24
US201562188030P 2015-07-02 2015-07-02
PCT/IB2015/002173 WO2016063134A1 (fr) 2014-10-24 2015-10-23 Thérapie pour l'inhibition de la réplication d'un virus à arn simple brin

Publications (1)

Publication Number Publication Date
SG11201703307WA true SG11201703307WA (en) 2017-05-30

Family

ID=55760346

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201703307WA SG11201703307WA (en) 2014-10-24 2015-10-23 Therapy for inhibition of single-stranded rna virus replication

Country Status (12)

Country Link
US (5) US9974800B2 (fr)
EP (2) EP4134076A1 (fr)
JP (1) JP6625631B2 (fr)
KR (1) KR20170070234A (fr)
CN (2) CN107106525B (fr)
AU (2) AU2015334590B2 (fr)
BR (1) BR112017008220A2 (fr)
CA (1) CA2965258C (fr)
IL (1) IL251847A0 (fr)
MX (1) MX2017005350A (fr)
SG (1) SG11201703307WA (fr)
WO (1) WO2016063134A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4134076A1 (fr) * 2014-10-24 2023-02-15 Redhill Biopharma Ltd. Thérapie pour l'inhibition de la réplication de virus rna simple brin
RU2727474C2 (ru) * 2015-10-06 2020-07-21 Редхилл Байофарма Лтд. Виды комбинированной терапии для лечения рака
CN108853106B (zh) * 2017-05-09 2021-02-02 中国食品药品检定研究院 亚胺吩嗪类化合物作为狂犬病病毒抑制剂的用途
US11548893B2 (en) 2017-07-15 2023-01-10 Arisan Therapeutics Inc. Enantiomerically pure adamantane carboxamides for the treatment of filovirus infection
DE102018217334A1 (de) 2018-10-10 2020-04-16 Harbins Ruhr Bioscience, Inc. Sphingoid-Base und/oder Wirkstoff zur Verwendung bei der Prophylaxe und/oder Therapie einer viralen Infektion und/oder viralen Infektionskrankheit oder der Desinfektion, Nahrungsmittel/Nahrungsergänzungsmittel, Futtermittel/Futterergänzungsmittel und Pflanzenschutzmittel
WO2020185637A1 (fr) * 2019-03-08 2020-09-17 The Texas A&M University System Clones infectieux du rose rosette virus et leurs utilisations
US20210244705A1 (en) * 2020-02-07 2021-08-12 Centre For Digestive Diseases Therapeutic compositions, products of manufacture and methods for ameliorating or preventing coronavirus infection
BR112022017923A2 (pt) * 2020-03-10 2022-10-18 Redhill Biopharma Ltd Tratamento de infecção por coronavírus
EP3932409A1 (fr) * 2020-06-29 2022-01-05 Consejo Superior de Investigaciones Científicas (CSIC) Composés pour le traitement et la prévention des infections virales causées par les coronavirus
US11298412B2 (en) 2020-07-16 2022-04-12 Harbins Ruhr Bioscience, Inc. Sphingoid compounds for prophylaxis and/or therapy of coronaviridae infection

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6503881B2 (en) * 1996-08-21 2003-01-07 Micrologix Biotech Inc. Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics
US6335339B1 (en) * 1998-01-13 2002-01-01 Scriptgen Pharmaceuticals, Inc. Triazine antiviral compounds
AP2001002051A0 (en) * 1998-07-15 2001-03-31 Hassan Jomaa Phosphorous organic compounds and their use.
ES2477118T3 (es) * 2002-11-18 2014-07-15 Polaris Group Método para inhibir la replicaci�n viral in vivo
US7338961B2 (en) * 2005-06-17 2008-03-04 Apogee Biotechnology Corporation Sphingosine kinase inhibitors
GB0803707D0 (en) 2008-02-28 2008-04-09 Cambridge Entpr Ltd Antiviral agent
KR101420094B1 (ko) * 2010-10-27 2014-07-17 (주)바이오니아 다양한 생체시료분석을 위한 전자동실시간정량증폭장비, 다양한 생체시료분석을 위한 자동정제 및 반응준비 장치, 전자동 핵산정제 및 실시간 정량 유전자증폭 방법, 전자동 핵산정제방법, 실시간정량pcr을 이용한 병원균의 전자동 생균수검사방법, 정량면역pcr을 이용한 전자동 항원농도획득방법 및 타겟항원에 라벨링된 부착용 타겟핵산의 정제방법
WO2012166859A2 (fr) * 2011-06-01 2012-12-06 The Curators Of The University Of Missouri Modulation des enzymes du métabolisme de la sphingosine 1-phosphate pour le traitement d'infections par un virus à arn à brin à polarité négative
EP4134076A1 (fr) * 2014-10-24 2023-02-15 Redhill Biopharma Ltd. Thérapie pour l'inhibition de la réplication de virus rna simple brin
RU2727474C2 (ru) * 2015-10-06 2020-07-21 Редхилл Байофарма Лтд. Виды комбинированной терапии для лечения рака

Also Published As

Publication number Publication date
EP4134076A1 (fr) 2023-02-15
US11786541B2 (en) 2023-10-17
US10543222B2 (en) 2020-01-28
US20200155585A1 (en) 2020-05-21
EP3209290A1 (fr) 2017-08-30
JP6625631B2 (ja) 2019-12-25
BR112017008220A2 (pt) 2018-01-09
US20240108643A1 (en) 2024-04-04
US20180318328A1 (en) 2018-11-08
CN107106525B (zh) 2021-03-19
AU2019271958B2 (en) 2020-03-05
IL251847A0 (en) 2017-06-29
JP2017531673A (ja) 2017-10-26
AU2019271958A1 (en) 2019-12-19
CN107106525A (zh) 2017-08-29
WO2016063134A1 (fr) 2016-04-28
AU2015334590A1 (en) 2017-05-18
CA2965258C (fr) 2023-09-19
MX2017005350A (es) 2017-08-15
CN112999222A (zh) 2021-06-22
AU2015334590B2 (en) 2019-08-29
CN112999222B (zh) 2024-05-28
CA2965258A1 (fr) 2016-04-28
EP3209290A4 (fr) 2018-11-14
US20210369754A1 (en) 2021-12-02
US11090325B2 (en) 2021-08-17
US9974800B2 (en) 2018-05-22
KR20170070234A (ko) 2017-06-21
US20160113954A1 (en) 2016-04-28

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