SG11201702516UA - Novel selection marker for cell transfection and protein production - Google Patents

Novel selection marker for cell transfection and protein production

Info

Publication number
SG11201702516UA
SG11201702516UA SG11201702516UA SG11201702516UA SG11201702516UA SG 11201702516U A SG11201702516U A SG 11201702516UA SG 11201702516U A SG11201702516U A SG 11201702516UA SG 11201702516U A SG11201702516U A SG 11201702516UA SG 11201702516U A SG11201702516U A SG 11201702516UA
Authority
SG
Singapore
Prior art keywords
selection marker
protein production
cell transfection
novel selection
novel
Prior art date
Application number
SG11201702516UA
Other languages
English (en)
Inventor
Bruno Dumas
Nabil Lounis
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of SG11201702516UA publication Critical patent/SG11201702516UA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/001Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/65Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y103/00Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/05Oxidoreductases acting on the CH-CH group of donors (1.3) with a quinone or related compound as acceptor (1.3.5)
    • C12Y103/05002Dihydroorotate dehydrogenase (1.3.5.2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11201702516UA 2014-10-23 2015-10-22 Novel selection marker for cell transfection and protein production SG11201702516UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14306689 2014-10-23
PCT/EP2015/074550 WO2016062837A1 (en) 2014-10-23 2015-10-22 Novel selection marker for cell transfection and protein production

Publications (1)

Publication Number Publication Date
SG11201702516UA true SG11201702516UA (en) 2017-04-27

Family

ID=51799064

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201702516UA SG11201702516UA (en) 2014-10-23 2015-10-22 Novel selection marker for cell transfection and protein production

Country Status (11)

Country Link
US (3) US10557125B2 (es)
EP (1) EP3209770B1 (es)
CN (1) CN107109435B (es)
AU (1) AU2015334872B2 (es)
CA (1) CA2965202C (es)
DK (1) DK3209770T3 (es)
ES (1) ES2769877T3 (es)
HU (1) HUE048525T2 (es)
MX (1) MX2017005295A (es)
SG (1) SG11201702516UA (es)
WO (1) WO2016062837A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2016001661A1 (es) 2016-06-29 2017-03-03 Univ Chile Promotor hibrido de ß-actina (de cricetulus griseus) y citomegalovirus (cmv), con región rica en dinucleótidos, citosina-guanina, vectores, líneas celulares, procedimiento para producir proteínas recombinantes.
CN111727244B (zh) * 2018-02-14 2023-09-15 休斯敦系统大学 循环肿瘤细胞的通用检测探针
WO2020188021A1 (en) 2019-03-19 2020-09-24 Sanofi Novel selection marker-comprising cell line and uses thereof for protein production
TW202227622A (zh) 2020-09-21 2022-07-16 法商賽諾菲公司 用於生產治療蛋白之高生產重組中國倉鼠卵巢細胞株之世代

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8717430D0 (en) 1987-07-23 1987-08-26 Celltech Ltd Recombinant dna product
KR100267720B1 (ko) 1997-12-29 2001-03-02 박호군 사람 글루타민 합성효소 유전자를 포함하는 발현벡터 및 이를 이용하여 동물세포에서 에리트로포이에틴을 고수율로 생산하는 방법
US20030166201A1 (en) * 2001-04-30 2003-09-04 Jensen Michael C. Selection systems for genetically modified cells
GB0808029D0 (en) 2008-05-01 2008-06-11 F2G Ltd Antifungal target
ES2640947T3 (es) 2009-05-11 2017-11-07 Pfenex, Inc. Producción de proteínas recombinantes utilizando métodos de selección no antibióticos y la incorporación de aminoácidos no naturales en las mismas
WO2012109329A2 (en) * 2011-02-08 2012-08-16 Children's Medical Center Corporation Methods for treatment of melanoma
EP2674495A1 (en) * 2012-06-14 2013-12-18 Sanofi CHO expression system
EP2935581A4 (en) 2012-12-21 2016-07-27 Merck Sharp & Dohme EXPRESSION VECTORS FOR THE PRODUCTION OF RECOMBINANT PROTEINS IN MAMMALIAN CELLS

Also Published As

Publication number Publication date
WO2016062837A1 (en) 2016-04-28
US20170335292A1 (en) 2017-11-23
CN107109435B (zh) 2021-10-22
US10557125B2 (en) 2020-02-11
AU2015334872A1 (en) 2017-06-08
CA2965202A1 (en) 2016-04-28
DK3209770T3 (da) 2020-02-24
US20230025088A1 (en) 2023-01-26
HUE048525T2 (hu) 2020-07-28
AU2015334872B2 (en) 2021-12-16
ES2769877T3 (es) 2020-06-29
US11384342B2 (en) 2022-07-12
US20200199543A1 (en) 2020-06-25
CA2965202C (en) 2023-02-28
EP3209770B1 (en) 2019-11-27
EP3209770A1 (en) 2017-08-30
CN107109435A (zh) 2017-08-29
MX2017005295A (es) 2017-07-28

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