SG11201702108PA - Histone demethylase inhibitors - Google Patents
Histone demethylase inhibitorsInfo
- Publication number
- SG11201702108PA SG11201702108PA SG11201702108PA SG11201702108PA SG11201702108PA SG 11201702108P A SG11201702108P A SG 11201702108PA SG 11201702108P A SG11201702108P A SG 11201702108PA SG 11201702108P A SG11201702108P A SG 11201702108PA SG 11201702108P A SG11201702108P A SG 11201702108PA
- Authority
- SG
- Singapore
- Prior art keywords
- histone demethylase
- demethylase inhibitors
- inhibitors
- histone
- demethylase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4192—1,2,3-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462051268P | 2014-09-16 | 2014-09-16 | |
| PCT/US2015/050289 WO2016044342A1 (fr) | 2014-09-16 | 2015-09-15 | Inhibiteurs de l'histone déméthylase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201702108PA true SG11201702108PA (en) | 2017-04-27 |
Family
ID=55533770
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201702108PA SG11201702108PA (en) | 2014-09-16 | 2015-09-15 | Histone demethylase inhibitors |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US9676770B2 (fr) |
| EP (1) | EP3193881B1 (fr) |
| JP (1) | JP6660060B2 (fr) |
| KR (1) | KR20170048590A (fr) |
| CN (1) | CN107073006A (fr) |
| AU (1) | AU2015317904A1 (fr) |
| BR (1) | BR112017005128A2 (fr) |
| CA (1) | CA2961525A1 (fr) |
| CL (1) | CL2017000643A1 (fr) |
| CO (1) | CO2017002772A2 (fr) |
| EA (1) | EA201790502A1 (fr) |
| EC (1) | ECSP17020172A (fr) |
| ES (1) | ES2911292T3 (fr) |
| IL (1) | IL251103A0 (fr) |
| MX (1) | MX2017003464A (fr) |
| SG (1) | SG11201702108PA (fr) |
| WO (1) | WO2016044342A1 (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2731773T3 (es) | 2013-03-14 | 2019-11-19 | Celgene Quanticel Res Inc | Inhibidores de la histona desmetilasa |
| US9896436B2 (en) | 2014-09-16 | 2018-02-20 | Celgene Quanticel Research, Inc. | Histone demethylase inhibitors |
| JP6660060B2 (ja) * | 2014-09-16 | 2020-03-04 | セルジーン クオンティセル リサーチ，インク． | ヒストンデメチラーゼ阻害剤 |
| WO2016130501A1 (fr) | 2015-02-09 | 2016-08-18 | Incyte Corporation | Composés aza-hétéroaryle en tant qu'inhibiteurs de pi3k-gamma |
| EP4086259A1 (fr) | 2015-11-06 | 2022-11-09 | Incyte Corporation | Composés hétérocycliques utilisés en tant qu'inhibiteurs de pi3k-gamma |
| ES2833955T3 (es) | 2016-01-05 | 2021-06-16 | Incyte Corp | Piridinas sustituidas con pirazol/imidazol como inhibidores de PI3K-Gamma |
| EP3436445B1 (fr) * | 2016-03-15 | 2023-09-06 | Celgene Quanticel Research, Inc. | Inhibiteurs de l'histone déméthylase |
| US10150754B2 (en) | 2016-04-19 | 2018-12-11 | Celgene Quanticel Research, Inc. | Histone demethylase inhibitors |
| AR108875A1 (es) | 2016-06-24 | 2018-10-03 | Incyte Corp | COMPUESTOS HETEROCÍCLICOS COMO INHIBIDORES DE PI3K-g |
| CA3084589A1 (fr) | 2017-10-18 | 2019-04-25 | Incyte Corporation | Derives d'imidazole condenses, substitues par des groupes hydroxy tertiaires, utilises comme inhibiteurs de pi3k-gamma |
| HUE066111T2 (hu) | 2018-09-05 | 2024-07-28 | Incyte Corp | Foszfoinozitid-3-kináz (PI3K) gátló kristályos formái |
| CN111116571B (zh) * | 2019-12-27 | 2022-07-12 | 吉首大学 | 含恶唑及三唑双杂环的化合物及其制备与应用方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2320730A1 (fr) | 1998-12-23 | 2000-07-06 | Renhua Li | Inhibiteurs du facteur xa ou de la thrombine |
| BR0114978A (pt) | 2000-10-26 | 2004-04-20 | Tularik Inc | Composições e métodos que são úteis no tratamento de condições ou doenças inflamatórias, metabólicas, e proliferativas celulares |
| GB0217780D0 (en) * | 2002-07-31 | 2002-09-11 | Glaxo Group Ltd | Compounds |
| US20040127733A1 (en) | 2002-10-31 | 2004-07-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New beta-agonists, processes for preparing them and their use as pharmaceutical compositions |
| DE102004021779A1 (de) | 2004-04-30 | 2005-11-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Beta-Agonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| US20090221589A1 (en) | 2005-12-19 | 2009-09-03 | Thomas Trieselmann | Use of aminoalcohol derivatives for the treatment of overactive bladder |
| JP2010540649A (ja) | 2007-10-03 | 2010-12-24 | バーテックス ファーマシューティカルズ インコーポレイテッド | ｃ−ＭＥＴタンパク質の阻害剤 |
| DE102009019962A1 (de) | 2009-05-05 | 2010-11-11 | Merck Patent Gmbh | 3-([1,2,3]Triazol-4-yl)-pyrrolo[2,3-b]pyridinderivate |
| ES2444543T3 (es) | 2009-11-10 | 2014-02-25 | Pfizer Inc | Inhibidores de la N1-pirazoloespirocetona acetil-CoA carboxilasa |
| MX341133B (es) | 2010-01-13 | 2016-08-08 | Tempero Pharmaceuticals Inc * | Compuestos y metodos para la inhibición de hdac. |
| US9604961B2 (en) * | 2012-12-06 | 2017-03-28 | Celgene Quanticel Research, Inc. | Histone demethylase inhibitors |
| ES2731773T3 (es) | 2013-03-14 | 2019-11-19 | Celgene Quanticel Res Inc | Inhibidores de la histona desmetilasa |
| US9695167B2 (en) | 2014-07-10 | 2017-07-04 | Incyte Corporation | Substituted triazolo[1,5-a]pyridines and triazolo[1,5-a]pyrazines as LSD1 inhibitors |
| US9896436B2 (en) * | 2014-09-16 | 2018-02-20 | Celgene Quanticel Research, Inc. | Histone demethylase inhibitors |
| JP6660060B2 (ja) | 2014-09-16 | 2020-03-04 | セルジーン クオンティセル リサーチ，インク． | ヒストンデメチラーゼ阻害剤 |
-
2015
- 2015-09-15 JP JP2017514411A patent/JP6660060B2/ja active Active
- 2015-09-15 EP EP15842092.7A patent/EP3193881B1/fr active Active
- 2015-09-15 SG SG11201702108PA patent/SG11201702108PA/en unknown
- 2015-09-15 US US14/855,269 patent/US9676770B2/en active Active
- 2015-09-15 EA EA201790502A patent/EA201790502A1/ru unknown
- 2015-09-15 CA CA2961525A patent/CA2961525A1/fr not_active Abandoned
- 2015-09-15 KR KR1020177009901A patent/KR20170048590A/ko unknown
- 2015-09-15 MX MX2017003464A patent/MX2017003464A/es unknown
- 2015-09-15 BR BR112017005128A patent/BR112017005128A2/pt not_active Application Discontinuation
- 2015-09-15 ES ES15842092T patent/ES2911292T3/es active Active
- 2015-09-15 AU AU2015317904A patent/AU2015317904A1/en not_active Abandoned
- 2015-09-15 CN CN201580060763.8A patent/CN107073006A/zh active Pending
- 2015-09-15 WO PCT/US2015/050289 patent/WO2016044342A1/fr active Application Filing
-
2017
- 2017-03-12 IL IL251103A patent/IL251103A0/en unknown
- 2017-03-16 CL CL2017000643A patent/CL2017000643A1/es unknown
- 2017-03-23 CO CONC2017/0002772A patent/CO2017002772A2/es unknown
- 2017-03-31 EC ECIEPI201720172A patent/ECSP17020172A/es unknown
- 2017-05-05 US US15/588,495 patent/US10071984B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2015317904A1 (en) | 2017-04-06 |
| EP3193881B1 (fr) | 2022-02-09 |
| US20160108033A1 (en) | 2016-04-21 |
| BR112017005128A2 (pt) | 2018-07-31 |
| WO2016044342A1 (fr) | 2016-03-24 |
| MX2017003464A (es) | 2017-07-13 |
| IL251103A0 (en) | 2017-04-30 |
| JP2017527590A (ja) | 2017-09-21 |
| EA201790502A1 (ru) | 2017-10-31 |
| US20170240529A1 (en) | 2017-08-24 |
| CN107073006A (zh) | 2017-08-18 |
| ECSP17020172A (es) | 2017-05-31 |
| CO2017002772A2 (es) | 2017-06-09 |
| US10071984B2 (en) | 2018-09-11 |
| CL2017000643A1 (es) | 2017-12-01 |
| KR20170048590A (ko) | 2017-05-08 |
| ES2911292T3 (es) | 2022-05-18 |
| US9676770B2 (en) | 2017-06-13 |
| JP6660060B2 (ja) | 2020-03-04 |
| EP3193881A1 (fr) | 2017-07-26 |
| EP3193881A4 (fr) | 2018-02-21 |
| CA2961525A1 (fr) | 2016-03-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL287113A (en) | smyd inhibitors | |
| IL249629A0 (en) | Histone demethylase inhibitors | |
| IL249281A0 (en) | Cyclopropylamine compounds as histone demethylase inhibitors | |
| IL250355A0 (en) | Compounds and methods for inhibiting histone demethylases | |
| IL246785A0 (en) | Benzimidazole-2-amines as midh1 inhibitors | |
| IL251103A0 (en) | Histone demethylase inhibitors | |
| GB201421083D0 (en) | Enzyme inhibitors | |
| EP2969007A4 (fr) | Inhibiteurs d'histone déméthylase | |
| PT2970211T (pt) | Inibidores de histona demetilase | |
| GB201421088D0 (en) | New enzyme inhibitors | |
| BR112017000043A2 (pt) | inibidores da desmetilase específica de lisina-1 | |
| IL248895A0 (en) | Phosphatidylinositol 3-kinase inhibitors | |
| HK1226398A1 (zh) | 作為midh1抑制劑的苯並咪唑-2-胺 | |
| IL251179A0 (en) | Histone demethylase inhibitors | |
| GB201421085D0 (en) | New enzyme inhibitors | |
| IL251184A0 (en) | Histone demethylase inhibitors | |
| GB201501004D0 (en) | Inhibitors | |
| IL256438B (en) | Histone deacetylase inhibitors | |
| EP3397617A4 (fr) | Inhibiteurs de l'histone déméthylase | |
| GB201400299D0 (en) | Corrosion inhibitors | |
| GB201418154D0 (en) | Inhibitors | |
| GB201400300D0 (en) | Corrosion inhibitors |