SG11201608825UA - Mirnas enhancing cell productivity - Google Patents

Mirnas enhancing cell productivity

Info

Publication number
SG11201608825UA
SG11201608825UA SG11201608825UA SG11201608825UA SG11201608825UA SG 11201608825U A SG11201608825U A SG 11201608825UA SG 11201608825U A SG11201608825U A SG 11201608825UA SG 11201608825U A SG11201608825U A SG 11201608825UA SG 11201608825U A SG11201608825U A SG 11201608825UA
Authority
SG
Singapore
Prior art keywords
mirnas
enhancing cell
cell productivity
productivity
enhancing
Prior art date
Application number
SG11201608825UA
Other languages
English (en)
Inventor
Simon Fischer
René Handrick
Kerstin Otte
Original Assignee
Hochschule Biberach
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hochschule Biberach filed Critical Hochschule Biberach
Publication of SG11201608825UA publication Critical patent/SG11201608825UA/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111—General methods applicable to biologically active non-coding nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/113—Antisense targeting other non-coding nucleic acids, e.g. antagomirs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C12N2310/141—MicroRNAs, miRNAs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2330/00—Production
    • C12N2330/50—Biochemical production, i.e. in a transformed host cell
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/106—Plasmid DNA for vertebrates
    • C12N2800/107—Plasmid DNA for vertebrates for mammalian

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG11201608825UA 2014-04-25 2015-04-24 Mirnas enhancing cell productivity SG11201608825UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14166041.5A EP2937417B1 (de) 2014-04-25 2014-04-25 miRNAs zur Erhöhung der Zellproduktivität
PCT/EP2015/058975 WO2015162274A2 (en) 2014-04-25 2015-04-24 Mirnas enhancing cell productivity

Publications (1)

Publication Number Publication Date
SG11201608825UA true SG11201608825UA (en) 2016-11-29

Family

ID=50630588

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201608825UA SG11201608825UA (en) 2014-04-25 2015-04-24 Mirnas enhancing cell productivity

Country Status (9)

Country Link
US (1) US20170044541A1 (de)
EP (2) EP2937417B1 (de)
JP (1) JP2017513526A (de)
KR (1) KR20160145814A (de)
CN (1) CN106459976A (de)
AU (1) AU2015250742A1 (de)
CA (1) CA2945888A1 (de)
SG (1) SG11201608825UA (de)
WO (1) WO2015162274A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190010496A1 (en) * 2016-01-14 2019-01-10 The Brigham And Women`S Hospital, Inc. Genome Editing for Treating Glioblastoma
CN107354227A (zh) * 2017-09-06 2017-11-17 苏州吉玛基因股份有限公司 microRNA探针一步法实时荧光定量PCR检测方法
CN110144324B (zh) * 2018-02-11 2023-11-28 苏州大学 丝素水凝胶包裹的过表达ncRNA的MSC外泌体制备方法
CN108611320A (zh) * 2018-05-17 2018-10-02 广东芙金干细胞再生医学有限公司 一种抗衰老的干细胞培养基及间充质干细胞培养方法
EP3898976A1 (de) * 2018-12-20 2021-10-27 Rnatives Inc. Synthetische mikrorna-mimika
DE102019122014A1 (de) 2019-08-15 2021-02-18 Technische Universität Darmstadt Reduktion der Knochenresorption, insbesondere bei chronischen Gelenkerkrankungen
CN110724712A (zh) * 2019-10-09 2020-01-24 重庆医科大学附属第一医院 一种miRNA海绵表达载体的构建方法及其应用
EP4061947A4 (de) * 2019-11-22 2024-04-24 California Inst Of Techn Verfahren zur robusten steuerung der genexpression
CN111944751B (zh) * 2020-08-24 2022-08-09 中国医科大学附属盛京医院 一种与干细胞增殖相关的Abca4基因及其应用
EP4119672A1 (de) * 2021-07-14 2023-01-18 Sartorius Stedim Cellca GmbH Verfahren zur modulation des ausmasses der galaktosylierung von proteinen in säugetierproduktionszellen
CN113577094B (zh) * 2021-09-08 2022-08-23 南通大学 miR-673-5P在制备促进周围神经再生的制剂中的应用
CN117695396B (zh) * 2024-02-05 2024-04-19 中国医学科学院北京协和医院 miR-3104-5p抑制剂在糖尿病治疗中的新用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010129919A1 (en) * 2009-05-08 2010-11-11 Research Development Foundation Mirna expression in allergic disease
EP2859103B1 (de) * 2012-06-06 2019-04-17 Boehringer Ingelheim International GmbH Zellzüchtung unter verwendung von rns
EP2880161A1 (de) * 2012-08-03 2015-06-10 Aptamir Therapeutics, Inc. Abgabe von zellspezifischen mirna-modulatoren zur behandlung von adipositas und verwandten erkrankungen
CN103397035A (zh) * 2013-08-14 2013-11-20 重庆大学 miRNA-20a作为哺乳动物宿主细胞凋亡调控靶标的应用

Also Published As

Publication number Publication date
KR20160145814A (ko) 2016-12-20
CN106459976A (zh) 2017-02-22
EP2937417A1 (de) 2015-10-28
US20170044541A1 (en) 2017-02-16
WO2015162274A3 (en) 2015-12-17
EP2937417B1 (de) 2019-02-20
WO2015162274A2 (en) 2015-10-29
AU2015250742A1 (en) 2016-11-17
CA2945888A1 (en) 2015-10-29
EP3134525A2 (de) 2017-03-01
JP2017513526A (ja) 2017-06-01

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