SG11201601681QA - Metabolically optimized cell culture - Google Patents

Metabolically optimized cell culture

Info

Publication number
SG11201601681QA
SG11201601681QA SG11201601681QA SG11201601681QA SG11201601681QA SG 11201601681Q A SG11201601681Q A SG 11201601681QA SG 11201601681Q A SG11201601681Q A SG 11201601681QA SG 11201601681Q A SG11201601681Q A SG 11201601681QA SG 11201601681Q A SG11201601681Q A SG 11201601681QA
Authority
SG
Singapore
Prior art keywords
cell culture
optimized cell
metabolically optimized
metabolically
culture
Prior art date
Application number
SG11201601681QA
Other languages
English (en)
Inventor
Shawn Lawrence
Ann Kim
Amy Johnson
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52813657&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201601681Q(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of SG11201601681QA publication Critical patent/SG11201601681QA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/16Animal cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0681Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0682Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/60Buffer, e.g. pH regulation, osmotic pressure
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2511/00Cells for large scale production

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Reproductive Health (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
SG11201601681QA 2013-10-11 2014-10-10 Metabolically optimized cell culture SG11201601681QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361889815P 2013-10-11 2013-10-11
PCT/US2014/059993 WO2015054554A1 (fr) 2013-10-11 2014-10-10 Culture cellulaire à métabolisme optimisé

Publications (1)

Publication Number Publication Date
SG11201601681QA true SG11201601681QA (en) 2016-04-28

Family

ID=52813657

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201800772TA SG10201800772TA (en) 2013-10-11 2014-10-10 Metabolically optimized cell culture
SG11201601681QA SG11201601681QA (en) 2013-10-11 2014-10-10 Metabolically optimized cell culture

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201800772TA SG10201800772TA (en) 2013-10-11 2014-10-10 Metabolically optimized cell culture

Country Status (18)

Country Link
US (2) US20160244725A1 (fr)
EP (3) EP3055409B1 (fr)
JP (3) JP6663854B2 (fr)
KR (4) KR102243980B1 (fr)
CN (2) CN105637085A (fr)
AU (2) AU2014331776B2 (fr)
CA (1) CA2926049C (fr)
DK (2) DK3351620T3 (fr)
EA (2) EA033783B1 (fr)
ES (2) ES2833471T3 (fr)
HK (2) HK1223122A1 (fr)
HU (2) HUE051049T2 (fr)
IL (2) IL244511A0 (fr)
MX (2) MX2016004564A (fr)
PL (2) PL3351620T3 (fr)
SG (2) SG10201800772TA (fr)
WO (1) WO2015054554A1 (fr)
ZA (1) ZA201601550B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11390663B2 (en) 2013-10-11 2022-07-19 Regeneron Pharmaceuticals, Inc. Metabolically optimized cell culture
KR102243980B1 (ko) 2013-10-11 2021-04-26 리제너론 파마슈티칼스 인코포레이티드 대사적으로 최적화된 세포 배양
US20160244726A1 (en) * 2013-10-11 2016-08-25 Regeneron Pharmaceuticals, Inc. Metabolically optimized cell culture
JP7260011B2 (ja) * 2017-03-31 2023-04-18 株式会社三洋物産 遊技機
JP7260020B2 (ja) * 2017-03-31 2023-04-18 株式会社三洋物産 遊技機
JP7260018B2 (ja) * 2017-03-31 2023-04-18 株式会社三洋物産 遊技機
JP7260013B2 (ja) * 2017-04-27 2023-04-18 株式会社三洋物産 遊技機
JP7260009B2 (ja) * 2017-04-27 2023-04-18 株式会社三洋物産 遊技機
JP7310947B2 (ja) * 2017-04-27 2023-07-19 株式会社三洋物産 遊技機
JP7272480B2 (ja) * 2017-04-27 2023-05-12 株式会社三洋物産 遊技機
JP7260012B2 (ja) * 2017-04-27 2023-04-18 株式会社三洋物産 遊技機
JP7260021B2 (ja) * 2017-04-27 2023-04-18 株式会社三洋物産 遊技機
JP7310952B2 (ja) * 2017-04-27 2023-07-19 株式会社三洋物産 遊技機
JP7310945B2 (ja) * 2017-04-27 2023-07-19 株式会社三洋物産 遊技機
JP7323512B2 (ja) 2017-10-06 2023-08-08 ロンザ リミテッド ラマン分光法を使用する細胞培養の自動制御
PL3697887T3 (pl) 2017-10-16 2022-08-01 Regeneron Pharmaceuticals, Inc. Sposoby perfuzyjne
US20200385673A1 (en) * 2017-11-30 2020-12-10 Hoffmann-La Roche Inc. Process for culturing mammalian cells
GB201810772D0 (en) * 2018-06-29 2018-08-15 Ge Healthcare Bio Sciences Ab Method in bioprocess purification system
JP2020151559A (ja) * 2020-06-24 2020-09-24 株式会社三洋物産 遊技機
JP2020151560A (ja) * 2020-06-24 2020-09-24 株式会社三洋物産 遊技機

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
KR970029803A (ko) 1995-11-03 1997-06-26 김광호 반도체 메모리장치의 프리차지 회로
US6165741A (en) 1997-05-30 2000-12-26 The Trustees Of The University Of Pennsylvania Method for rapid detection of bacterial growth in cultures
US5972650A (en) 1997-06-26 1999-10-26 Brigham And Women's Hospital Tetracycline repressor regulated mammalian cell transcription and viral replication switch
AU2002245272B2 (en) 2001-01-16 2006-06-29 Regeneron Pharmaceuticals, Inc. Isolating cells expressing secreted proteins
US6953692B2 (en) * 2001-12-18 2005-10-11 Bayer Pharmaceuticals Corporation Device and method for seed-train expansion of mammalian cells
US7039770B1 (en) 2002-03-05 2006-05-02 Juniper Networks, Inc. Low latency request dispatcher
CA2417689C (fr) 2002-03-05 2006-05-09 F. Hoffmann-La Roche Ag Methodes ameliorees de culture in vitro de cellules de mammiferes
US8673589B2 (en) 2002-05-29 2014-03-18 Regeneron Pharmaceuticals, Inc. Inducible eukaryotic expression system
EP1623019B2 (fr) 2003-05-15 2017-01-25 Wyeth LLC Alimentation de glucose restreinte pour culture de cellules animales
US7531327B2 (en) * 2004-07-23 2009-05-12 Immunomedics, Inc. Methods and compositions for increasing longevity and protein yield from a cell culture
US7300773B2 (en) * 2004-08-27 2007-11-27 Wyeth Research Ireland Limited Production of TNFR-Ig
TWI374935B (en) * 2004-08-27 2012-10-21 Pfizer Ireland Pharmaceuticals Production of α-abeta
EP1943333A2 (fr) * 2005-11-02 2008-07-16 Wyeth a Corporation of the State of Delaware Procedes pour adapter des cellules de mammifere
KR20080090406A (ko) 2005-11-28 2008-10-08 젠맵 에이/에스 재조합 1가 항체 및 그의 제조 방법
US7575890B2 (en) 2006-01-18 2009-08-18 Oxygen Enterprises, Ltd. Method for rapid detection and evaluation of cultured cell growth
CA2666317C (fr) 2006-11-03 2013-08-06 Wyeth Substances inhibant la glycolyse dans une culture de cellules
PL2150617T3 (pl) 2007-06-04 2015-04-30 Regeneron Pharma Wzmocniona ekspresja i regiony stabilności
WO2009023562A2 (fr) 2007-08-09 2009-02-19 Wyeth Utilisation de la perfusion pour améliorer la production d'une culture cellulaire en mode semi-continu dans des bioréacteurs
UA106047C2 (uk) * 2008-06-13 2014-07-25 Сентокор Орто Байотек Інк. Спосіб отримання високої щільності життєздатних клітин в культурі клітин ссавців
US8470552B2 (en) * 2009-10-12 2013-06-25 Keck Graduate Institute Strategy to reduce lactic acid production and control PH in animal cell culture
PL2563904T3 (pl) * 2010-04-26 2015-06-30 Novartis Ag Udoskonalona pożywka do hodowli komórkowej
RU2614125C2 (ru) * 2010-05-28 2017-03-22 Дженентек, Инк. Снижение уровня лактата и увеличение продукции полипептида путем ингибирования экспрессии лактатдегидрогеназы и киназы пируватдегидрогеназы
TWI637057B (zh) 2012-11-09 2018-10-01 拜爾沙納有限公司 具交替生物反應器用途之不連續進料批次製程
KR102243980B1 (ko) 2013-10-11 2021-04-26 리제너론 파마슈티칼스 인코포레이티드 대사적으로 최적화된 세포 배양

Also Published As

Publication number Publication date
IL244511A0 (en) 2016-04-21
KR102610425B1 (ko) 2023-12-06
EP3055409B1 (fr) 2018-04-25
CA2926049C (fr) 2023-09-05
CN105637085A (zh) 2016-06-01
ES2833471T3 (es) 2021-06-15
CN114717196A (zh) 2022-07-08
MX2016004564A (es) 2016-07-12
PL3055409T3 (pl) 2018-10-31
KR102510238B1 (ko) 2023-03-16
EP3055409A4 (fr) 2016-09-28
HK1223122A1 (zh) 2017-07-21
KR102358807B1 (ko) 2022-02-08
HUE039551T2 (hu) 2019-01-28
EA033783B1 (ru) 2019-11-25
EP3351620B1 (fr) 2020-09-02
EA201991976A1 (ru) 2020-04-02
EP3351620A1 (fr) 2018-07-25
EP3812453A1 (fr) 2021-04-28
JP7377243B2 (ja) 2023-11-09
JP6663854B2 (ja) 2020-03-13
JP2020072760A (ja) 2020-05-14
KR20210046835A (ko) 2021-04-28
US20160244725A1 (en) 2016-08-25
KR20220020415A (ko) 2022-02-18
SG10201800772TA (en) 2018-03-28
IL262833A (en) 2018-12-31
KR102243980B1 (ko) 2021-04-26
ZA201601550B (en) 2023-05-31
US20210087535A1 (en) 2021-03-25
ES2678945T3 (es) 2018-08-21
AU2021200193B2 (en) 2023-08-24
EP3055409A1 (fr) 2016-08-17
AU2014331776B2 (en) 2020-10-22
HK1253275A1 (zh) 2019-06-14
WO2015054554A1 (fr) 2015-04-16
DK3351620T3 (da) 2020-10-26
JP6967620B2 (ja) 2021-11-17
KR20230038324A (ko) 2023-03-17
JP2016532457A (ja) 2016-10-20
KR20160062032A (ko) 2016-06-01
AU2014331776A1 (en) 2016-03-24
PL3351620T3 (pl) 2021-03-08
EA201690600A1 (ru) 2016-09-30
MX2020011334A (es) 2021-07-30
HUE051049T2 (hu) 2021-01-28
DK3055409T3 (en) 2018-07-30
AU2021200193A1 (en) 2021-03-18
CA2926049A1 (fr) 2015-04-16
JP2022009453A (ja) 2022-01-14

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