SG11201507739TA - Method for predicting sensitivity to egfr inhibitor - Google Patents
Method for predicting sensitivity to egfr inhibitorInfo
- Publication number
- SG11201507739TA SG11201507739TA SG11201507739TA SG11201507739TA SG11201507739TA SG 11201507739T A SG11201507739T A SG 11201507739TA SG 11201507739T A SG11201507739T A SG 11201507739TA SG 11201507739T A SG11201507739T A SG 11201507739TA SG 11201507739T A SG11201507739T A SG 11201507739TA
- Authority
- SG
- Singapore
- Prior art keywords
- egfr inhibitor
- predicting sensitivity
- predicting
- sensitivity
- egfr
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2013057033 | 2013-03-19 | ||
PCT/JP2014/057556 WO2014148557A1 (ja) | 2013-03-19 | 2014-03-19 | Egfr阻害剤感受性予測方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201507739TA true SG11201507739TA (en) | 2015-10-29 |
Family
ID=51580231
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201507739TA SG11201507739TA (en) | 2013-03-19 | 2014-03-19 | Method for predicting sensitivity to egfr inhibitor |
SG10201707548RA SG10201707548RA (en) | 2013-03-19 | 2014-03-19 | Method for predicting sensitivity to egfr inhibitor |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201707548RA SG10201707548RA (en) | 2013-03-19 | 2014-03-19 | Method for predicting sensitivity to egfr inhibitor |
Country Status (6)
Country | Link |
---|---|
US (1) | US20160002741A1 (ja) |
EP (1) | EP2977464A4 (ja) |
JP (1) | JP6520705B2 (ja) |
CN (1) | CN105074009B (ja) |
SG (2) | SG11201507739TA (ja) |
WO (1) | WO2014148557A1 (ja) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012129363A2 (en) | 2011-03-24 | 2012-09-27 | President And Fellows Of Harvard College | Single cell nucleic acid detection and analysis |
US20160040229A1 (en) | 2013-08-16 | 2016-02-11 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
US10876152B2 (en) | 2012-09-04 | 2020-12-29 | Guardant Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
IL305303A (en) | 2012-09-04 | 2023-10-01 | Guardant Health Inc | Systems and methods for detecting rare mutations and changes in number of copies |
US11913065B2 (en) | 2012-09-04 | 2024-02-27 | Guardent Health, Inc. | Systems and methods to detect rare mutations and copy number variation |
JP2015096049A (ja) * | 2013-11-15 | 2015-05-21 | 凸版印刷株式会社 | Vegf阻害剤長期奏功性予測方法 |
CN106062214B (zh) | 2013-12-28 | 2020-06-09 | 夸登特健康公司 | 用于检测遗传变异的方法和系统 |
WO2016103727A1 (ja) * | 2014-12-25 | 2016-06-30 | 凸版印刷株式会社 | 特異的核酸配列の増幅促進方法 |
CN108603228B (zh) | 2015-12-17 | 2023-09-01 | 夸登特健康公司 | 通过分析无细胞dna确定肿瘤基因拷贝数的方法 |
WO2017110764A1 (ja) * | 2015-12-24 | 2017-06-29 | 公益財団法人がん研究会 | マルチキナーゼ阻害剤の有効性と安全性を予測する検査方法、検査キット、及びバイオマーカー |
WO2017187937A1 (ja) | 2016-04-28 | 2017-11-02 | デンカ株式会社 | 上皮性細胞成長因子受容体阻害剤に対する癌細胞の耐性を判定する方法 |
JP2019202936A (ja) * | 2016-08-17 | 2019-11-28 | 中外製薬株式会社 | 抗Epiregulin抗体と抗EGFR抗体との併用医薬 |
JP7215675B2 (ja) * | 2017-01-16 | 2023-01-31 | 凸版印刷株式会社 | 腫瘍状態の評価方法 |
CN111032092A (zh) * | 2017-06-30 | 2020-04-17 | 韩国科学技术院 | Vegf-grab蛋白与药物的缀合物及其用途 |
WO2019043059A1 (en) * | 2017-08-30 | 2019-03-07 | Symphogen A/S | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER BY ANTI-EGFR ANTIBODIES |
CN108998535B (zh) * | 2018-09-11 | 2021-09-10 | 广州市宝创生物技术有限公司 | 一种kras基因多重突变位点检测试剂盒 |
MX2022006700A (es) | 2019-12-02 | 2022-09-02 | Storm Therapeutics Ltd | Compuestos poliheterociclicos como inhibidores de mettl3. |
CN112162042B (zh) * | 2020-09-14 | 2022-04-26 | 首都医科大学附属北京朝阳医院 | 超高效液相色谱串联质谱测定血浆中amg510浓度的方法 |
CA3212669A1 (en) * | 2021-03-09 | 2022-09-15 | Janssen Biotech, Inc. | Treatment of cancers lacking egfr-activating mutations |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4943533A (en) | 1984-03-01 | 1990-07-24 | The Regents Of The University Of California | Hybrid cell lines that produce monoclonal antibodies to epidermal growth factor receptor |
IE61148B1 (en) | 1988-03-10 | 1994-10-05 | Ici Plc | Method of detecting nucleotide sequences |
US5679683A (en) | 1994-01-25 | 1997-10-21 | Warner-Lambert Company | Tricyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family |
EP2118322A2 (en) * | 2007-03-13 | 2009-11-18 | Amgen Inc. | K-ras and b-raf mutations and anti-egfr antibody therapy |
CA2680326A1 (en) * | 2007-03-13 | 2008-09-18 | Amgen Inc. | K-ras mutations and anti-egfr antibody therapy |
US20110320392A1 (en) * | 2009-03-02 | 2011-12-29 | Black Esther P | Methods for predicting cancer response to egfr inhibitors |
JP2012135290A (ja) * | 2010-12-28 | 2012-07-19 | Fuaruko Bio Syst:Kk | 高感度K−ras遺伝子変異解析法による分子標的薬の治療感受性の評価法 |
US20140134158A1 (en) * | 2012-05-22 | 2014-05-15 | Alberto Bardelli | Kras mutations and resistance to anti-egfr treatment |
-
2014
- 2014-03-19 EP EP14767593.8A patent/EP2977464A4/en not_active Withdrawn
- 2014-03-19 CN CN201480017000.0A patent/CN105074009B/zh active Active
- 2014-03-19 JP JP2015506829A patent/JP6520705B2/ja active Active
- 2014-03-19 SG SG11201507739TA patent/SG11201507739TA/en unknown
- 2014-03-19 SG SG10201707548RA patent/SG10201707548RA/en unknown
- 2014-03-19 WO PCT/JP2014/057556 patent/WO2014148557A1/ja active Application Filing
-
2015
- 2015-09-17 US US14/857,187 patent/US20160002741A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2977464A1 (en) | 2016-01-27 |
SG10201707548RA (en) | 2017-10-30 |
WO2014148557A1 (ja) | 2014-09-25 |
CN105074009A (zh) | 2015-11-18 |
JP6520705B2 (ja) | 2019-05-29 |
JPWO2014148557A1 (ja) | 2017-02-16 |
CN105074009B (zh) | 2017-09-26 |
US20160002741A1 (en) | 2016-01-07 |
EP2977464A4 (en) | 2016-10-19 |
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