SG11201505202SA - Materials and methods for removing endotoxins from protein preparations - Google Patents

Materials and methods for removing endotoxins from protein preparations

Info

Publication number
SG11201505202SA
SG11201505202SA SG11201505202SA SG11201505202SA SG11201505202SA SG 11201505202S A SG11201505202S A SG 11201505202SA SG 11201505202S A SG11201505202S A SG 11201505202SA SG 11201505202S A SG11201505202S A SG 11201505202SA SG 11201505202S A SG11201505202S A SG 11201505202SA
Authority
SG
Singapore
Prior art keywords
materials
methods
protein preparations
removing endotoxins
endotoxins
Prior art date
Application number
SG11201505202SA
Other languages
English (en)
Inventor
Peter Stanley Gagnon
Vincent Vagenende
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Publication of SG11201505202SA publication Critical patent/SG11201505202SA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/34—Size selective separation, e.g. size exclusion chromatography, gel filtration, permeation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • B01D15/363—Anion-exchange
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3847—Multimodal interactions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
SG11201505202SA 2013-02-22 2014-02-20 Materials and methods for removing endotoxins from protein preparations SG11201505202SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361768232P 2013-02-22 2013-02-22
PCT/SG2014/000071 WO2014129973A1 (en) 2013-02-22 2014-02-20 Materials and methods for removing endotoxins from protein preparations

Publications (1)

Publication Number Publication Date
SG11201505202SA true SG11201505202SA (en) 2015-08-28

Family

ID=51391629

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201505202SA SG11201505202SA (en) 2013-02-22 2014-02-20 Materials and methods for removing endotoxins from protein preparations

Country Status (7)

Country Link
US (1) US9695216B2 (de)
EP (1) EP2958931B9 (de)
JP (1) JP6385374B2 (de)
KR (1) KR20150118120A (de)
CN (1) CN105121457B (de)
SG (1) SG11201505202SA (de)
WO (1) WO2014129973A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2855504B1 (de) * 2012-05-31 2018-10-24 Agency For Science, Technology And Research Chromatografische reinigung von immunglobulin-g-zubereitungen mit teilchen mit multimodalen funktionalitäten
SG10201610955SA (en) * 2013-02-26 2017-02-27 Agency Science Tech & Res Protein purification in the presence of nonionic organic polymers and electropositive surfaces
EP2961761B1 (de) * 2013-02-28 2018-09-12 Agency For Science, Technology And Research Proteinreinigung in gegenwart von nichtionischen organischen polymeren bei hoher leitfähigkeit
CN105251049B (zh) * 2015-09-29 2018-04-10 浙江星月生物科技股份有限公司 一种去除生物医用材料中细菌内毒素的离子缓冲液及应用
JP7137818B2 (ja) 2018-05-09 2022-09-15 白光株式会社 スポンジ部材
CN113166792B (zh) * 2018-12-14 2024-06-25 赛多利斯比亚分离有限责任公司 一种用于从含内毒素源或潜在含内毒素源中去掉或去除内毒素的方法
CN112391367A (zh) * 2019-08-13 2021-02-23 西安宇繁生物科技有限责任公司 一种可用于人原代细胞基因编辑的Cas9蛋白的制备方法
JP2022547159A (ja) 2019-09-06 2022-11-10 ビーアイエー セパレーションズ ディー．オー．オー． 生物学的調製物のクロマチン含有量を低減する組成物及び方法
CN111289642B (zh) * 2020-03-04 2021-03-02 苏州金纬标检测有限公司 液相色谱串联质谱定量检测纳米材料表面脂多糖的方法
KR102596822B1 (ko) 2020-03-20 2023-11-02 에이치엘비사이언스 주식회사 리포폴리사카라이드 제거용 조성물 및 키트
CN113493570B (zh) * 2020-04-01 2022-11-01 中国科学院理化技术研究所 一种采用尿囊素降低明胶中内毒素的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101271089B (zh) * 2005-05-12 2012-07-25 新疆医科大学 一种鉴定肉苁蓉属植物品种的方法
EP2855504B1 (de) * 2012-05-31 2018-10-24 Agency For Science, Technology And Research Chromatografische reinigung von immunglobulin-g-zubereitungen mit teilchen mit multimodalen funktionalitäten

Also Published As

Publication number Publication date
JP2016514101A (ja) 2016-05-19
US9695216B2 (en) 2017-07-04
EP2958931B9 (de) 2020-04-15
WO2014129973A1 (en) 2014-08-28
EP2958931A4 (de) 2016-10-05
EP2958931B1 (de) 2019-09-18
EP2958931A1 (de) 2015-12-30
US20160002290A1 (en) 2016-01-07
CN105121457B (zh) 2019-04-30
KR20150118120A (ko) 2015-10-21
CN105121457A (zh) 2015-12-02
JP6385374B2 (ja) 2018-09-05

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