SG11201505202SA - Materials and methods for removing endotoxins from protein preparations - Google Patents

Materials and methods for removing endotoxins from protein preparations

Info

Publication number
SG11201505202SA
SG11201505202SA SG11201505202SA SG11201505202SA SG11201505202SA SG 11201505202S A SG11201505202S A SG 11201505202SA SG 11201505202S A SG11201505202S A SG 11201505202SA SG 11201505202S A SG11201505202S A SG 11201505202SA SG 11201505202S A SG11201505202S A SG 11201505202SA
Authority
SG
Singapore
Prior art keywords
materials
methods
protein preparations
removing endotoxins
endotoxins
Prior art date
Application number
SG11201505202SA
Inventor
Peter Stanley Gagnon
Vincent Vagenende
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Publication of SG11201505202SA publication Critical patent/SG11201505202SA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/34Size selective separation, e.g. size exclusion chromatography, gel filtration, permeation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361Ion-exchange
    • B01D15/363Anion-exchange
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/30Extraction; Separation; Purification by precipitation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3847Multimodal interactions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
SG11201505202SA 2013-02-22 2014-02-20 Materials and methods for removing endotoxins from protein preparations SG11201505202SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361768232P 2013-02-22 2013-02-22
PCT/SG2014/000071 WO2014129973A1 (en) 2013-02-22 2014-02-20 Materials and methods for removing endotoxins from protein preparations

Publications (1)

Publication Number Publication Date
SG11201505202SA true SG11201505202SA (en) 2015-08-28

Family

ID=51391629

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201505202SA SG11201505202SA (en) 2013-02-22 2014-02-20 Materials and methods for removing endotoxins from protein preparations

Country Status (7)

Country Link
US (1) US9695216B2 (en)
EP (1) EP2958931B9 (en)
JP (1) JP6385374B2 (en)
KR (1) KR20150118120A (en)
CN (1) CN105121457B (en)
SG (1) SG11201505202SA (en)
WO (1) WO2014129973A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013180647A1 (en) * 2012-05-31 2013-12-05 Agency For Science, Technology And Research Chromatographic purification of immunoglobulin g preparations with particles having multimodal functionalities
WO2014133458A1 (en) * 2013-02-26 2014-09-04 Agency For Science, Technology And Research Protein purification in the presence of nonionic organic polymers and electropositive surfaces
CN105008384A (en) * 2013-02-28 2015-10-28 新加坡科技研究局 Protein purification in the presence of nonionic organic polymers at elevated conductivity
CN105251049B (en) * 2015-09-29 2018-04-10 浙江星月生物科技股份有限公司 The ion buffer solution of bacterial endotoxin and application in a kind of removal bio-medical material
JP7137818B2 (en) 2018-05-09 2022-09-15 白光株式会社 Sponge member
CN112391367A (en) * 2019-08-13 2021-02-23 西安宇繁生物科技有限责任公司 Preparation method of Cas9 protein for gene editing of human primary cells
JP2022547159A (en) 2019-09-06 2022-11-10 ビーアイエー セパレーションズ ディー.オー.オー. Compositions and methods for reducing chromatin content of biological preparations
CN111289642B (en) * 2020-03-04 2021-03-02 苏州金纬标检测有限公司 Method for quantitatively detecting lipopolysaccharide on surface of nano material by liquid chromatography-tandem mass spectrometry
KR102596822B1 (en) 2020-03-20 2023-11-02 에이치엘비사이언스 주식회사 Composition and Kit for removing lipopolysaccharide
CN113493570B (en) * 2020-04-01 2022-11-01 中国科学院理化技术研究所 Method for reducing endotoxin in gelatin by adopting allantoin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101271089B (en) * 2005-05-12 2012-07-25 新疆医科大学 Method for identifying allantoin in Cistanche plant variety
WO2013180647A1 (en) * 2012-05-31 2013-12-05 Agency For Science, Technology And Research Chromatographic purification of immunoglobulin g preparations with particles having multimodal functionalities

Also Published As

Publication number Publication date
CN105121457B (en) 2019-04-30
CN105121457A (en) 2015-12-02
EP2958931A4 (en) 2016-10-05
WO2014129973A1 (en) 2014-08-28
KR20150118120A (en) 2015-10-21
JP2016514101A (en) 2016-05-19
JP6385374B2 (en) 2018-09-05
US9695216B2 (en) 2017-07-04
EP2958931B9 (en) 2020-04-15
EP2958931A1 (en) 2015-12-30
US20160002290A1 (en) 2016-01-07
EP2958931B1 (en) 2019-09-18

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