SG11201500156SA - Use of vegfr-3 inhibitors for treating hepatocellular carcinoma - Google Patents

Use of vegfr-3 inhibitors for treating hepatocellular carcinoma

Info

Publication number
SG11201500156SA
SG11201500156SA SG11201500156SA SG11201500156SA SG11201500156SA SG 11201500156S A SG11201500156S A SG 11201500156SA SG 11201500156S A SG11201500156S A SG 11201500156SA SG 11201500156S A SG11201500156S A SG 11201500156SA SG 11201500156S A SG11201500156S A SG 11201500156SA
Authority
SG
Singapore
Prior art keywords
vegfr
inhibitors
hepatocellular carcinoma
treating hepatocellular
treating
Prior art date
Application number
SG11201500156SA
Other languages
English (en)
Inventor
Antoine Alam
Isabelle Blanc
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of SG11201500156SA publication Critical patent/SG11201500156SA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11201500156SA 2012-07-17 2013-07-16 Use of vegfr-3 inhibitors for treating hepatocellular carcinoma SG11201500156SA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261672489P 2012-07-17 2012-07-17
EP12305866 2012-07-17
PCT/EP2013/065029 WO2014012942A1 (en) 2012-07-17 2013-07-16 Use of vegfr-3 inhibitors for treating hepatocellular carcinoma

Publications (1)

Publication Number Publication Date
SG11201500156SA true SG11201500156SA (en) 2015-02-27

Family

ID=49948312

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201500156SA SG11201500156SA (en) 2012-07-17 2013-07-16 Use of vegfr-3 inhibitors for treating hepatocellular carcinoma

Country Status (31)

Country Link
US (1) US9376432B2 (es)
EP (1) EP2874625B1 (es)
JP (1) JP6226981B2 (es)
KR (1) KR102068860B1 (es)
CN (1) CN104602691B (es)
AU (1) AU2013292054B2 (es)
BR (1) BR112015000942A2 (es)
CA (1) CA2878987C (es)
CL (1) CL2015000115A1 (es)
CR (1) CR20150029A (es)
CY (1) CY1119415T1 (es)
DK (1) DK2874625T3 (es)
EA (1) EA027982B1 (es)
ES (1) ES2635105T3 (es)
HK (1) HK1206257A1 (es)
HR (1) HRP20171227T1 (es)
HU (1) HUE035712T2 (es)
IL (1) IL236718A (es)
LT (1) LT2874625T (es)
MA (1) MA37821A1 (es)
MX (1) MX367402B (es)
PH (1) PH12015500094A1 (es)
PL (1) PL2874625T3 (es)
PT (1) PT2874625T (es)
RS (1) RS56178B1 (es)
SG (1) SG11201500156SA (es)
SI (1) SI2874625T1 (es)
TN (1) TN2015000021A1 (es)
TW (1) TW201406759A (es)
WO (1) WO2014012942A1 (es)
ZA (1) ZA201500182B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2524915A1 (en) * 2011-05-20 2012-11-21 Sanofi 2-Amino-3-(imidazol-2-yl)-pyridin-4-one derivatives and their use as VEGF receptor kinase inhibitors
WO2014026243A1 (en) 2012-08-17 2014-02-20 Cancer Therapeutics Crc Pty Limited Vegfr3 inhibitors
WO2014026242A1 (en) 2012-08-17 2014-02-20 Cancer Therapeutics Crc Pty Limited Vegfr3 inhibitors

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2760456B1 (fr) * 1997-03-05 2000-05-12 Sanofi Sa Procede de preparation de derives de 2-thienyl-ethylamine
US5994367A (en) * 1997-03-07 1999-11-30 The University Of North Carolina At Chapel Hill Method for treating tumors using 2-aryl-naphthyridin-4-ones
CN1191252C (zh) * 2003-08-11 2005-03-02 中国药科大学 3-位取代的喹诺酮衍生物及其在药学上的应用
WO2005046589A2 (en) * 2003-11-07 2005-05-26 Chiron Corporation Pharmaceutically acceptable salts of quinolinone compounds having improved pharmaceutical properties
CN1325494C (zh) * 2005-08-18 2007-07-11 中国药科大学 3-位取代的萘啶酮类化合物及其制备方法和在制药中的应用
KR100744826B1 (ko) * 2006-04-05 2007-08-01 한국화학연구원 이미다졸기가 치환된 퀴놀리논 유도체
FR2917412B1 (fr) * 2007-06-13 2009-08-21 Sanofi Aventis Sa Derives de 7-alkynyl, 1,8-naphthyridones, leur preparation et leur application en therapeutique
WO2009053799A1 (en) * 2007-10-24 2009-04-30 Glenmark Pharmaceuticals, S.A. Novel cannabinoid receptor ligands, pharmaceutical compositions containing them, and process for their preparation
FR2933700B1 (fr) * 2008-07-08 2010-07-30 Sanofi Aventis Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique
FR2933701A1 (fr) * 2008-07-08 2010-01-15 Sanofi Aventis Derives anticancereux, leur preparation et leur application en therapeutique
WO2010073078A2 (en) 2008-12-22 2010-07-01 Orchid Research Laboratories Ltd. Heterocyclic compounds as hdac inhibitors
FR2952934B1 (fr) * 2009-11-23 2012-06-22 Sanofi Aventis Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique
EP2524915A1 (en) * 2011-05-20 2012-11-21 Sanofi 2-Amino-3-(imidazol-2-yl)-pyridin-4-one derivatives and their use as VEGF receptor kinase inhibitors

Also Published As

Publication number Publication date
AU2013292054B2 (en) 2017-08-03
CA2878987A1 (en) 2014-01-23
PT2874625T (pt) 2017-08-16
EA027982B1 (ru) 2017-09-29
CA2878987C (en) 2020-07-21
CN104602691A (zh) 2015-05-06
IL236718A0 (en) 2015-02-26
EP2874625A1 (en) 2015-05-27
DK2874625T3 (en) 2017-09-11
JP6226981B2 (ja) 2017-11-08
RS56178B1 (sr) 2017-11-30
EP2874625B1 (en) 2017-05-17
CR20150029A (es) 2015-04-06
LT2874625T (lt) 2017-08-25
ES2635105T3 (es) 2017-10-02
PL2874625T3 (pl) 2017-10-31
KR102068860B1 (ko) 2020-01-21
HK1206257A1 (en) 2016-01-08
JP2015522598A (ja) 2015-08-06
EA201590229A1 (ru) 2015-05-29
WO2014012942A1 (en) 2014-01-23
CN104602691B (zh) 2016-12-28
CY1119415T1 (el) 2018-03-07
TW201406759A (zh) 2014-02-16
SI2874625T1 (sl) 2017-10-30
AU2013292054A1 (en) 2015-02-05
MX2015000797A (es) 2015-08-13
TN2015000021A1 (en) 2016-06-29
HUE035712T2 (en) 2018-05-28
IL236718A (en) 2017-11-30
KR20150036401A (ko) 2015-04-07
MX367402B (es) 2019-08-20
US9376432B2 (en) 2016-06-28
HRP20171227T1 (hr) 2017-10-20
US20150183780A1 (en) 2015-07-02
CL2015000115A1 (es) 2015-05-04
MA37821A1 (fr) 2018-02-28
BR112015000942A2 (pt) 2017-06-27
PH12015500094A1 (en) 2015-03-02
ZA201500182B (en) 2015-12-23

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