SG11201408813VA - Highly multiplex pcr methods and compositions - Google Patents
Highly multiplex pcr methods and compositionsInfo
- Publication number
- SG11201408813VA SG11201408813VA SG11201408813VA SG11201408813VA SG11201408813VA SG 11201408813V A SG11201408813V A SG 11201408813VA SG 11201408813V A SG11201408813V A SG 11201408813VA SG 11201408813V A SG11201408813V A SG 11201408813VA SG 11201408813V A SG11201408813V A SG 11201408813VA
- Authority
- SG
- Singapore
- Prior art keywords
- compositions
- multiplex pcr
- pcr methods
- highly multiplex
- highly
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/10—Ploidy or copy number detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/20—Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261675020P | 2012-07-24 | 2012-07-24 | |
| US13/683,604 US20130123120A1 (en) | 2010-05-18 | 2012-11-21 | Highly Multiplex PCR Methods and Compositions |
| PCT/US2012/066339 WO2014018080A1 (en) | 2012-07-24 | 2012-11-21 | Highly multiplex pcr methods and compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201408813VA true SG11201408813VA (en) | 2015-02-27 |
Family
ID=49997695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201408813VA SG11201408813VA (en) | 2012-07-24 | 2012-11-21 | Highly multiplex pcr methods and compositions |
Country Status (10)
| Country | Link |
|---|---|
| JP (10) | JP6392222B2 (ja) |
| KR (1) | KR101890466B1 (ja) |
| CN (1) | CN104685064A (ja) |
| AU (1) | AU2012385961B9 (ja) |
| CA (1) | CA2877493C (ja) |
| HK (1) | HK1211058A1 (ja) |
| IL (1) | IL236435A0 (ja) |
| RU (1) | RU2650790C2 (ja) |
| SG (1) | SG11201408813VA (ja) |
| WO (1) | WO2014018080A1 (ja) |
Families Citing this family (56)
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| US10083273B2 (en) | 2005-07-29 | 2018-09-25 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US11111543B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US10081839B2 (en) | 2005-07-29 | 2018-09-25 | Natera, Inc | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US11111544B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
| CA2731991C (en) | 2008-08-04 | 2021-06-08 | Gene Security Network, Inc. | Methods for allele calling and ploidy calling |
| ES2640776T3 (es) | 2009-09-30 | 2017-11-06 | Natera, Inc. | Métodos para denominar de forma no invasiva ploidía prenatal |
| AU2011255641A1 (en) | 2010-05-18 | 2012-12-06 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11326208B2 (en) | 2010-05-18 | 2022-05-10 | Natera, Inc. | Methods for nested PCR amplification of cell-free DNA |
| US11332793B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11339429B2 (en) | 2010-05-18 | 2022-05-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| US11332785B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| ES2770342T3 (es) | 2010-12-22 | 2020-07-01 | Natera Inc | Procedimientos para pruebas prenatales no invasivas de paternidad |
| CA2824387C (en) | 2011-02-09 | 2019-09-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| CN103717751A (zh) | 2011-05-19 | 2014-04-09 | 塞昆纳姆股份有限公司 | 用于多重核酸鉴定的产品和方法 |
| RU2650790C2 (ru) * | 2012-07-24 | 2018-04-17 | Натера, Инк. | Способы и композиции для высокомультиплексной пцр |
| US10262755B2 (en) | 2014-04-21 | 2019-04-16 | Natera, Inc. | Detecting cancer mutations and aneuploidy in chromosomal segments |
| US9499870B2 (en) | 2013-09-27 | 2016-11-22 | Natera, Inc. | Cell free DNA diagnostic testing standards |
| US10577655B2 (en) | 2013-09-27 | 2020-03-03 | Natera, Inc. | Cell free DNA diagnostic testing standards |
| WO2015164432A1 (en) * | 2014-04-21 | 2015-10-29 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| RU2717641C2 (ru) | 2014-04-21 | 2020-03-24 | Натера, Инк. | Обнаружение мутаций и плоидности в хромосомных сегментах |
| EP3224376B2 (en) | 2014-11-28 | 2023-04-26 | uniQure IP B.V. | Dna impurities in a composition comprising a parvoviral virion |
| US20170349926A1 (en) * | 2014-12-22 | 2017-12-07 | DNAe Group Holdings LTD. | Bubble primers |
| WO2016172571A1 (en) | 2015-04-24 | 2016-10-27 | Agena Bioscience, Inc. | Multiplexed method for the identification and quantitation of minor alleles and polymorphisms |
| WO2016183106A1 (en) * | 2015-05-11 | 2016-11-17 | Natera, Inc. | Methods and compositions for determining ploidy |
| GB2539675B (en) * | 2015-06-23 | 2017-11-22 | Cs Genetics Ltd | Libraries of multimeric barcoding reagents and kits thereof for labelling nucleic acids for sequencing |
| JP2018530536A (ja) | 2015-09-11 | 2018-10-18 | ザ ジェネラル ホスピタル コーポレイション | ヌクレアーゼＤＳＢの完全照合およびシーケンシング（ＦＩＮＤ−ｓｅｑ） |
| ES2874275T3 (es) * | 2016-02-25 | 2021-11-04 | Hoffmann La Roche | Eliminación de las interacciones cebador-cebador durante la extensión del cebador |
| AU2017249594B2 (en) * | 2016-04-15 | 2023-08-24 | Natera, Inc. | Methods for lung cancer detection |
| MX2019001276A (es) * | 2016-07-29 | 2019-06-13 | Univ California | Viriones de virus adenoasociados con cápside variante y métodos para su uso. |
| CN109790587B (zh) * | 2016-09-30 | 2023-06-13 | 富士胶片株式会社 | 从100pg以下的人类基因组DNA判别其来源的方法、识别个人的方法及分析造血干细胞的植活程度的方法 |
| US11485996B2 (en) | 2016-10-04 | 2022-11-01 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
| US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
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| WO2019010456A1 (en) * | 2017-07-07 | 2019-01-10 | Stephen Quake | NON-INVASIVE PRENATAL DIAGNOSIS OF SINGLE GENE DISORDERS USING DIGITAL DROPLET PCR |
| KR101977976B1 (ko) * | 2017-08-10 | 2019-05-14 | 주식회사 엔젠바이오 | 앰플리콘 기반 차세대 염기서열 분석기법에서 프라이머 서열을 제거하여 분석의 정확도를 높이는 방법 |
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| CA3107376A1 (en) | 2018-08-08 | 2020-02-13 | Inivata Ltd. | Method of sequencing using variable replicate multiplex pcr |
| CN112080558B (zh) * | 2019-06-13 | 2024-03-12 | 杭州贝瑞和康基因诊断技术有限公司 | 同时检测hba1/2和hbb基因突变的试剂盒和方法 |
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| JP7320468B2 (ja) | 2020-03-10 | 2023-08-03 | Ntn株式会社 | 操舵機能付ハブユニットおよびこれを備えた車両 |
| CN113979895B (zh) * | 2020-07-08 | 2023-03-24 | 中国科学技术大学 | 一种精确序列可控的自降解聚合物及其制备方法和应用 |
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-
2012
- 2012-11-21 RU RU2014152883A patent/RU2650790C2/ru active
- 2012-11-21 JP JP2015524243A patent/JP6392222B2/ja active Active
- 2012-11-21 CA CA2877493A patent/CA2877493C/en active Active
- 2012-11-21 CN CN201280075224.8A patent/CN104685064A/zh active Pending
- 2012-11-21 SG SG11201408813VA patent/SG11201408813VA/en unknown
- 2012-11-21 AU AU2012385961A patent/AU2012385961B9/en active Active
- 2012-11-21 WO PCT/US2012/066339 patent/WO2014018080A1/en active Application Filing
- 2012-11-21 KR KR1020157004509A patent/KR101890466B1/ko active IP Right Grant
-
2014
- 2014-12-24 IL IL236435A patent/IL236435A0/en unknown
-
2015
- 2015-12-02 HK HK15111834.0A patent/HK1211058A1/xx unknown
-
2018
- 2018-08-16 JP JP2018153048A patent/JP6916153B2/ja active Active
-
2020
- 2020-01-16 JP JP2020005462A patent/JP7027468B2/ja active Active
- 2020-01-16 JP JP2020005502A patent/JP6997815B2/ja active Active
- 2020-01-16 JP JP2020005470A patent/JP6997813B2/ja active Active
- 2020-01-16 JP JP2020005493A patent/JP6997814B2/ja active Active
-
2021
- 2021-12-17 JP JP2021204905A patent/JP7343563B2/ja active Active
- 2021-12-17 JP JP2021204979A patent/JP2022037145A/ja active Pending
- 2021-12-17 JP JP2021205050A patent/JP2022027975A/ja active Pending
-
2022
- 2022-02-14 JP JP2022020146A patent/JP7348330B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP6997813B2 (ja) | 2022-02-10 |
| JP2020054401A (ja) | 2020-04-09 |
| JP6997814B2 (ja) | 2022-02-10 |
| AU2012385961A1 (en) | 2015-02-12 |
| JP2020058388A (ja) | 2020-04-16 |
| JP2018183189A (ja) | 2018-11-22 |
| JP6916153B2 (ja) | 2021-08-11 |
| RU2014152883A (ru) | 2016-09-10 |
| KR101890466B1 (ko) | 2018-08-21 |
| JP6997815B2 (ja) | 2022-02-10 |
| RU2650790C2 (ru) | 2018-04-17 |
| JP7343563B2 (ja) | 2023-09-12 |
| CA2877493A1 (en) | 2014-01-30 |
| JP2022037145A (ja) | 2022-03-08 |
| JP7027468B2 (ja) | 2022-03-01 |
| JP7348330B2 (ja) | 2023-09-20 |
| KR20150038216A (ko) | 2015-04-08 |
| WO2014018080A1 (en) | 2014-01-30 |
| JP2015526073A (ja) | 2015-09-10 |
| JP2020054402A (ja) | 2020-04-09 |
| CN104685064A (zh) | 2015-06-03 |
| CA2877493C (en) | 2020-08-25 |
| AU2012385961B2 (en) | 2017-04-13 |
| AU2012385961B9 (en) | 2017-05-18 |
| JP2020054400A (ja) | 2020-04-09 |
| JP2022051949A (ja) | 2022-04-01 |
| JP2022027975A (ja) | 2022-02-14 |
| JP6392222B2 (ja) | 2018-09-19 |
| JP2022027971A (ja) | 2022-02-14 |
| HK1211058A1 (en) | 2016-05-13 |
| IL236435A0 (en) | 2015-02-26 |
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