SG11201406727QA - Apparatus and method for separating a biological entity from a sample volume - Google Patents
Apparatus and method for separating a biological entity from a sample volumeInfo
- Publication number
- SG11201406727QA SG11201406727QA SG11201406727QA SG11201406727QA SG11201406727QA SG 11201406727Q A SG11201406727Q A SG 11201406727QA SG 11201406727Q A SG11201406727Q A SG 11201406727QA SG 11201406727Q A SG11201406727Q A SG 11201406727QA SG 11201406727Q A SG11201406727Q A SG 11201406727QA
- Authority
- SG
- Singapore
- Prior art keywords
- separating
- sample volume
- biological entity
- entity
- biological
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
- G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/30—Combinations with other devices, not otherwise provided for
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/22—Details of magnetic or electrostatic separation characterised by the magnetic field, e.g. its shape or generation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Dispersion Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- General Engineering & Computer Science (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SG11201406727QA SG11201406727QA (en) | 2012-04-20 | 2013-04-19 | Apparatus and method for separating a biological entity from a sample volume |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SG2012029435 | 2012-04-20 | ||
SG11201406727QA SG11201406727QA (en) | 2012-04-20 | 2013-04-19 | Apparatus and method for separating a biological entity from a sample volume |
PCT/SG2013/000156 WO2013158044A1 (fr) | 2012-04-20 | 2013-04-19 | Appareil et procédé pour séparer une entité biologique d'un volume d'échantillon |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201406727QA true SG11201406727QA (en) | 2014-11-27 |
Family
ID=55131482
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201406727QA SG11201406727QA (en) | 2012-04-20 | 2013-04-19 | Apparatus and method for separating a biological entity from a sample volume |
Country Status (4)
Country | Link |
---|---|
US (1) | US20150118728A1 (fr) |
EP (1) | EP2838581A4 (fr) |
SG (1) | SG11201406727QA (fr) |
WO (1) | WO2013158044A1 (fr) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10151672B2 (en) | 2014-02-11 | 2018-12-11 | Wallac Oy | Device and a method for managing a sample to be analyzed and a solid sample carrier and liquid sample carrier |
CN106574290A (zh) * | 2014-07-30 | 2017-04-19 | 日立化成株式会社 | 血中稀少细胞捕获方法 |
US20170269086A1 (en) * | 2014-07-30 | 2017-09-21 | Hitachi Chemical Company, Ltd. | Method for capturing rare cells in blood |
US9885699B2 (en) * | 2014-07-31 | 2018-02-06 | Becton, Dickinson And Company | Methods for processing whole blood samples, and compositions for use in practicing the same |
US10251990B2 (en) | 2016-04-29 | 2019-04-09 | Fenwal, Inc. | System and method for processing, incubating, and/or selecting biological cells |
US10449283B2 (en) | 2016-04-29 | 2019-10-22 | Fenwal, Inc. | System and method for selecting and culturing cells |
EP3499228A4 (fr) * | 2016-08-12 | 2020-04-15 | Hitachi Chemical Company, Ltd. | Procédé de détection de cellules cancéreuses circulantes dans le sang, et procédé de prétraitement destiné à détecter des cellules cancéreuses circulantes dans le sang |
WO2018052847A1 (fr) * | 2016-09-13 | 2018-03-22 | Gulamari Ltd. | Dispositifs de filtre microfluidique et procédés |
US20180100850A1 (en) * | 2016-10-06 | 2018-04-12 | Arkray, Inc. | Method for Collecting Rare Cells |
EP3338823B1 (fr) | 2016-12-21 | 2021-06-16 | Fenwal, Inc. | Système et procédé pour séparer des cellules incorporant une séparation magnétique |
CN107219360B (zh) * | 2017-07-03 | 2018-04-03 | 南京岚煜生物科技有限公司 | 单通道化学发光微流控芯片及其检测方法 |
EP3801809B1 (fr) * | 2018-05-30 | 2024-05-15 | The Regents of University of California | Dispositif de filtre microfluidique et procédé de dissociation de tissus et d'agrégats cellulaires et enrichissement de cellules individuelles |
CN108795692B (zh) * | 2018-06-26 | 2021-01-01 | 成都普瑞康生物科技有限公司 | 稀有细胞捕获系统及其应用 |
EP3837544A4 (fr) * | 2018-08-16 | 2022-08-03 | SiMPore Inc. | Dispositifs, procédés, et kits pour l'analyse d'échantillon au moyen de filtres à microfente |
CN112823202B (zh) * | 2018-08-24 | 2023-12-19 | 深圳华大生命科学研究院 | 细胞及生物分子分离提取装置及测试系统 |
CN110180613B (zh) * | 2019-06-27 | 2020-02-14 | 电子科技大学 | 一种基于表面电荷的移液枪 |
CN110540933B (zh) * | 2019-08-30 | 2024-05-10 | 杭州华得森生物技术有限公司 | 一种循环稀有细胞集成微流控分离装置及方法 |
CN112779118A (zh) * | 2019-11-07 | 2021-05-11 | 北京机械设备研究所 | 一种循环肿瘤细胞正向分离系统 |
US20210237064A1 (en) | 2020-01-31 | 2021-08-05 | Astrin Biosciences, Inc. | Biological Fluid Filtration System |
CN111979098A (zh) * | 2020-09-11 | 2020-11-24 | 安徽贝铭生物科技有限公司 | 一种细胞过滤器 |
DE102020215567A1 (de) * | 2020-12-09 | 2022-06-09 | Robert Bosch Gesellschaft mit beschränkter Haftung | Rückhaltevorrichtung und Verfahren zur Separierung von Zellen |
CN113186098B (zh) * | 2021-05-28 | 2024-03-26 | 宁波康程德诺生物医药有限公司 | 一种一体化下开口核酸快提试管、快提检测装置及方法 |
US20220410160A1 (en) * | 2021-06-09 | 2022-12-29 | Beijing Boe Technology Development Co., Ltd. | Microfluidic chip and microfluidic device |
DE102023204412A1 (de) * | 2023-05-12 | 2024-11-14 | Robert Bosch Gesellschaft mit beschränkter Haftung | Mikrofluidische Vorrichtung und Verfahren zum Abreichern von Leukozyten in einer Probe |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5167812A (en) * | 1984-11-28 | 1992-12-01 | Trustees Of The Univ. Of Penna. | Affinity chromatogry using dried calcium alginate-magnetite separation media in a magnetically stabilized fluidized bed |
DE60000014T2 (de) * | 2000-05-16 | 2002-05-02 | Biochip Technologies Gmbh | Linker-System zum Aktivieren von Oberflächen für die Biokonjugation und Verfahren zu ihrer Verwendung |
EP1439897B1 (fr) * | 2001-10-11 | 2010-09-01 | Aviva Biosciences Corporation | Methodes pour la separation des cellules rares provenant d'echantillons de fluides |
WO2003049530A2 (fr) * | 2001-12-07 | 2003-06-19 | Dyax Corporation | Procede et appareil de lavage de particules a reponse magnetique |
WO2005028663A2 (fr) * | 2003-09-18 | 2005-03-31 | Immunivest Corporation | Systeme d'analyse et de preparation d'echantillon programmable independamment de l'operateur |
EP1691925A1 (fr) * | 2003-12-17 | 2006-08-23 | Inverness Medical Switzerland GmbH | Systeme |
US7846393B2 (en) * | 2005-04-21 | 2010-12-07 | California Institute Of Technology | Membrane filter for capturing circulating tumor cells |
JP4699840B2 (ja) * | 2005-08-31 | 2011-06-15 | ローム株式会社 | バイオチップ及び免疫分析方法 |
EP2041299A4 (fr) * | 2006-07-14 | 2010-01-13 | Aviva Biosciences Corp | Procedes et compositions servant a detecter des cellules rares dans un echantillon biologique |
ES2977359T3 (es) * | 2010-01-19 | 2024-08-22 | Sirigen Ii Ltd | Nuevos reactivos para la amplificación dirigida de la señal de un biomarcador |
-
2013
- 2013-04-19 EP EP13777640.7A patent/EP2838581A4/fr not_active Withdrawn
- 2013-04-19 WO PCT/SG2013/000156 patent/WO2013158044A1/fr active Application Filing
- 2013-04-19 US US14/395,602 patent/US20150118728A1/en not_active Abandoned
- 2013-04-19 SG SG11201406727QA patent/SG11201406727QA/en unknown
Also Published As
Publication number | Publication date |
---|---|
US20150118728A1 (en) | 2015-04-30 |
WO2013158044A1 (fr) | 2013-10-24 |
EP2838581A4 (fr) | 2016-03-02 |
EP2838581A1 (fr) | 2015-02-25 |
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