SG11201405530SA - Esketamine for the treatment of treatment-refractory or treatment-resistant depression - Google Patents
Esketamine for the treatment of treatment-refractory or treatment-resistant depressionInfo
- Publication number
- SG11201405530SA SG11201405530SA SG11201405530SA SG11201405530SA SG11201405530SA SG 11201405530S A SG11201405530S A SG 11201405530SA SG 11201405530S A SG11201405530S A SG 11201405530SA SG 11201405530S A SG11201405530S A SG 11201405530SA SG 11201405530S A SG11201405530S A SG 11201405530SA
- Authority
- SG
- Singapore
- Prior art keywords
- treatment
- esketamine
- refractory
- resistant depression
- depression
- Prior art date
Links
- YQEZLKZALYSWHR-ZDUSSCGKSA-N (S)-ketamine Chemical compound C=1C=CC=C(Cl)C=1[C@@]1(NC)CCCCC1=O YQEZLKZALYSWHR-ZDUSSCGKSA-N 0.000 title 1
- 208000028552 Treatment-Resistant Depressive disease Diseases 0.000 title 1
- 229960000450 esketamine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261609641P | 2012-03-12 | 2012-03-12 | |
| US201261610058P | 2012-03-13 | 2012-03-13 | |
| PCT/US2013/030476 WO2013138322A1 (en) | 2012-03-12 | 2013-03-12 | Esketamine for the treatment of treatment-refractory or treatment-resistant depression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201405530SA true SG11201405530SA (en) | 2014-11-27 |
Family
ID=47913632
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201405530SA SG11201405530SA (en) | 2012-03-12 | 2013-03-12 | Esketamine for the treatment of treatment-refractory or treatment-resistant depression |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20130236573A1 (es) |
| KR (1) | KR20140136982A (es) |
| CN (1) | CN104519878A (es) |
| CL (1) | CL2014002406A1 (es) |
| CO (1) | CO7071129A2 (es) |
| CR (1) | CR20140410A (es) |
| GT (1) | GT201400191A (es) |
| HK (1) | HK1209323A1 (es) |
| MX (1) | MX2014010939A (es) |
| NI (1) | NI201400104A (es) |
| PE (1) | PE20141906A1 (es) |
| PH (1) | PH12014501997A1 (es) |
| SG (1) | SG11201405530SA (es) |
| WO (1) | WO2013138322A1 (es) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9737531B2 (en) | 2012-07-12 | 2017-08-22 | Glytech, Llc | Composition and method for treatment of depression and psychosis in humans |
| US10583138B2 (en) | 2012-07-12 | 2020-03-10 | Glytech, Llc | Composition and method for treatment of depression and psychosis in humans |
| CN105073096A (zh) | 2013-03-15 | 2015-11-18 | 詹森药业有限公司 | S-盐酸氯胺酮的药物组合物 |
| PL2983787T3 (pl) | 2013-04-12 | 2020-04-30 | Icahn School Of Medicine At Mount Sinai | Sposób leczenia zespołu stresu pourazowego |
| PT3043785T (pt) | 2013-09-13 | 2021-11-05 | Univ Chiba Nat Univ Corp | Aplicação de r-cetamina e seu sal como medicamentos |
| ES2726223T3 (es) * | 2014-01-14 | 2019-10-02 | Childrens Hospital Med Ct | Composiciones que comprenden ketamina para el tratamiento de un trastorno del espectro autista |
| KR20220102662A (ko) * | 2014-05-06 | 2022-07-20 | 노쓰웨스턴유니버시티 | Nmdar 조절 화합물의 조합물 |
| CA2957926A1 (en) * | 2014-08-13 | 2016-02-18 | Janssen Pharmaceutica Nv | Method for the treatment of depression |
| MX2017003366A (es) * | 2014-09-15 | 2018-02-01 | Janssen Pharmaceutica Nv | Regimenes de dosificacion y métodos especificos para el tratamiento de la depresión con el genotipo val66met (snp rs6265). |
| CA2970065A1 (en) | 2014-12-08 | 2016-06-16 | Cima Labs Inc. | Immediate release abuse-deterrent granulated dosage forms |
| US20180015054A1 (en) * | 2014-12-31 | 2018-01-18 | Icahn School Of Medicine At Mount Sinai | Method of Maintaining the Anti-Depressant Effect of Ketamine With Lithium |
| US9844551B2 (en) | 2015-01-14 | 2017-12-19 | Children's Hospital Medical Center | Compositions and methods for treatment of fragile X syndrome |
| WO2016172672A1 (en) * | 2015-04-24 | 2016-10-27 | Icahn School Of Medicine At Mount Sinai | Method for treating suicidal ideation |
| US20160332962A1 (en) | 2015-05-13 | 2016-11-17 | Janssen Pharmaceutica Nv | (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine |
| US20160338977A1 (en) * | 2015-05-20 | 2016-11-24 | Janssen Pharmaceutica Nv | Methods and kits for treating depression |
| CA2987909C (en) | 2015-06-27 | 2022-04-26 | Shenox Pharmaceuticals, Llc | Ketamine transdermal delivery system |
| CN106562952B (zh) * | 2015-10-09 | 2020-06-09 | 江阴安博生物医药有限公司 | 氯胺酮在治疗重性抑郁障碍中的应用 |
| WO2017087691A1 (en) | 2015-11-17 | 2017-05-26 | The Trustees Of Columbia University In The City Of New York | Pharmacological prophylactics against stress-induced affective disorders and their associated symptoms |
| CA3041275A1 (en) * | 2016-10-27 | 2018-05-03 | National University Corporation Chiba University | Pharmaceutical applications for (s)-norketamine and salts thereof |
| US11723883B2 (en) | 2017-06-23 | 2023-08-15 | Ketabon Gmbh | Hydroxynorketamine for the use in the treatment of depression |
| US20200009081A1 (en) | 2017-09-13 | 2020-01-09 | Janssen Pharmaceutica N.V. | Delivery Of Esketamine For The Treatment Of Depression |
| US11622948B2 (en) | 2017-11-09 | 2023-04-11 | The Trustees Of Columbia University In The City Of New York | Biomarkers for efficacy of prophylactic treatments against stress-induced affective disorders |
| CN107823195A (zh) * | 2017-11-24 | 2018-03-23 | 无锡市精神卫生中心 | R‑氯胺酮在抑郁症急性期治疗中的应用 |
| RU2020123893A (ru) * | 2017-12-22 | 2022-01-24 | Янссен Фармасьютикалз, Инк. | Эскетамин для лечения депрессии |
| EP3505157B1 (en) | 2017-12-29 | 2021-12-08 | Celon Pharma S.A. | Dry powder ketamine composition for pulmonary administration in treatment-resistant depression |
| EP3753557A4 (en) | 2018-02-15 | 2021-12-01 | National University Corporation Chiba University | PREVENTIVE OR THERAPEUTIC AGENT AND PHARMACEUTICAL COMPOSITION FOR INFLAMMATORY DISEASES OR BONE DISEASES |
| CN118121577A (zh) | 2018-05-04 | 2024-06-04 | 感知神经科学公司 | 治疗物质滥用的方法 |
| JP2021529732A (ja) * | 2018-06-27 | 2021-11-04 | クレキシオ バイオサイエンシーズ エルティーディー． | 大うつ病性障害の処置方法 |
| WO2020027344A1 (en) * | 2018-08-03 | 2020-02-06 | Takeda Pharmaceutical Company Limited | Ch24h inhibitors for mdd use |
| EP3628313A1 (en) | 2018-09-28 | 2020-04-01 | Celon Pharma S.A. | Ketamine composition for use in a method of treatment of depression by pulmonary administration |
| CN112702995A (zh) | 2018-10-05 | 2021-04-23 | 克雷西奥生物科技有限公司 | 治疗重度抑郁症的艾氯胺酮的治疗方案 |
| CA3130580A1 (en) * | 2019-02-17 | 2020-08-20 | Neurawell Therapeutics | Compositions and methods for treatment of depression and other disorders |
| US20230117657A1 (en) * | 2019-03-05 | 2023-04-20 | Janssen Pharmaceuticals, Inc. | Esketamine for the treatment of depression |
| WO2020239243A1 (en) | 2019-05-31 | 2020-12-03 | Celon Pharma S.A. | Electronically supervised administration of a pharmaceutical composition |
| BR112021024141A2 (pt) | 2019-05-31 | 2022-01-11 | Celon Pharma Sa | Inalador para administração parenteral supervisionada eletronicamente de uma composição farmacêutica |
| CN114286674A (zh) * | 2019-08-28 | 2022-04-05 | 杨森制药公司 | 用于治疗患有包括自杀倾向在内的重性抑郁障碍的患者的艾司氯胺酮 |
| BR112022004497A2 (pt) * | 2019-09-13 | 2022-05-31 | Janssen Pharmaceuticals Inc | Administração intranasal de escetamina |
| EP4157240A1 (en) * | 2020-05-28 | 2023-04-05 | JANSSEN Pharmaceutica NV | Methods for treating depression |
| WO2023162987A1 (ja) * | 2022-02-22 | 2023-08-31 | 国立大学法人京都大学 | うつ病および／またはうつ状態の治療および／または予防用医薬 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6176242B1 (en) * | 1999-04-30 | 2001-01-23 | Medtronic Inc | Method of treating manic depression by brain infusion |
| EP1103256A1 (de) * | 1999-11-26 | 2001-05-30 | Claudius Dr. med. Böck | Verwendung von Ketamin zur Behandlung von neuroendokriner Immundysfunktion und algogenem Psychosyndrom |
| MXPA05000294A (es) * | 2002-07-30 | 2005-08-19 | Peter Migaly | Terapia combinada para la depresion, prevencion de suicidios y varias condiciones medicas y psiquiatricas. |
| US7273889B2 (en) * | 2002-09-25 | 2007-09-25 | Innovative Drug Delivery Systems, Inc. | NMDA receptor antagonist formulation with reduced neurotoxicity |
| KR20090029690A (ko) * | 2006-03-22 | 2009-03-23 | 마운트 시나이 스쿨 오브 메디신 오브 뉴욕 유니버시티 | 우울증을 치료하기 위한 케타민의 투여 방법 |
| AU2007253684A1 (en) * | 2006-05-22 | 2007-11-29 | Vanda Pharmaceuticals, Inc. | Treatment for depressive disorders |
| DE102007009888A1 (de) * | 2007-02-28 | 2008-09-04 | Hermann, Holger Lars, Dr. | Verwendung von S-(+)-Ketamin zur Behandlung von Depressionen |
| US20110038807A1 (en) * | 2009-08-14 | 2011-02-17 | Demitri Papolos | Compositions and methods for treating bipolar disorder |
| WO2011157391A1 (en) * | 2010-06-15 | 2011-12-22 | Grünenthal GmbH | Pharmaceutical combination for the treatment of pain |
-
2013
- 2013-03-12 US US13/795,454 patent/US20130236573A1/en not_active Abandoned
- 2013-03-12 PE PE2014001406A patent/PE20141906A1/es not_active Application Discontinuation
- 2013-03-12 SG SG11201405530SA patent/SG11201405530SA/en unknown
- 2013-03-12 CN CN201380013908.XA patent/CN104519878A/zh active Pending
- 2013-03-12 MX MX2014010939A patent/MX2014010939A/es unknown
- 2013-03-12 WO PCT/US2013/030476 patent/WO2013138322A1/en active Application Filing
- 2013-03-12 KR KR1020147028246A patent/KR20140136982A/ko not_active Application Discontinuation
- 2013-12-05 US US14/098,498 patent/US20140093592A1/en not_active Abandoned
-
2014
- 2014-09-04 CR CR20140410A patent/CR20140410A/es unknown
- 2014-09-08 PH PH12014501997A patent/PH12014501997A1/en unknown
- 2014-09-10 NI NI201400104A patent/NI201400104A/es unknown
- 2014-09-10 CO CO14200330A patent/CO7071129A2/es unknown
- 2014-09-11 GT GT201400191A patent/GT201400191A/es unknown
- 2014-09-11 CL CL2014002406A patent/CL2014002406A1/es unknown
-
2015
- 2015-10-14 HK HK15110013.5A patent/HK1209323A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PE20141906A1 (es) | 2014-12-05 |
| KR20140136982A (ko) | 2014-12-01 |
| US20140093592A1 (en) | 2014-04-03 |
| PH12014501997A1 (en) | 2014-11-24 |
| NI201400104A (es) | 2016-11-30 |
| HK1209323A1 (en) | 2016-04-01 |
| CO7071129A2 (es) | 2014-09-30 |
| MX2014010939A (es) | 2014-11-13 |
| CR20140410A (es) | 2014-11-17 |
| CL2014002406A1 (es) | 2015-01-09 |
| CN104519878A (zh) | 2015-04-15 |
| GT201400191A (es) | 2017-07-03 |
| US20130236573A1 (en) | 2013-09-12 |
| WO2013138322A1 (en) | 2013-09-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1209323A1 (en) | Esketamine for the treatment of treatment-refractory or treatment- resistant depression | |
| HK1211475A1 (en) | Combination therapy | |
| IL263661A (en) | Combination therapy for the treatment of glioblastoma | |
| GB201212513D0 (en) | Therapeutic agents | |
| GB201304031D0 (en) | Medical applicator | |
| EP2906208A4 (en) | THERAPEUTIC TREATMENT | |
| GB201217439D0 (en) | Combination therapy | |
| HK1211986A1 (en) | Platelet targeted treatment | |
| GB201217704D0 (en) | Therapeutic agents | |
| GB201207305D0 (en) | Therapy | |
| IL237776B (en) | Medical applicator | |
| HK1210426A1 (en) | Combination therapy | |
| GB201207907D0 (en) | Treatment of depression | |
| HUE036419T2 (hu) | Légzõszervi depresszió kezelése | |
| HK1210421A1 (en) | Use of pregn-4-en-20-yn-3-one for the treatment of depressive disorders -4--20--3- | |
| EP2908871A4 (en) | ABSTRACT PROCESSING TECHNIQUES | |
| AP2015008270A0 (en) | Preparation for the treatment of tuberculosis | |
| GB201211543D0 (en) | Combination therapy | |
| GB201211135D0 (en) | Treatment | |
| GB201208690D0 (en) | Treatment | |
| GB201212604D0 (en) | New treatment | |
| GB201223021D0 (en) | Therapeutic agents | |
| GB201214985D0 (en) | Modified therapeutic agents | |
| GB201213712D0 (en) | Modified therapeutic agents | |
| GB201212512D0 (en) | Therapeutic agents |