SG11201402661TA - Therapeutic agents comprising insulin amino acid sequences - Google Patents

Therapeutic agents comprising insulin amino acid sequences

Info

Publication number
SG11201402661TA
SG11201402661TA SG11201402661TA SG11201402661TA SG11201402661TA SG 11201402661T A SG11201402661T A SG 11201402661TA SG 11201402661T A SG11201402661T A SG 11201402661TA SG 11201402661T A SG11201402661T A SG 11201402661TA SG 11201402661T A SG11201402661T A SG 11201402661TA
Authority
SG
Singapore
Prior art keywords
amino acid
acid sequences
therapeutic agents
insulin amino
insulin
Prior art date
Application number
SG11201402661TA
Other languages
English (en)
Inventor
James Jowett
Christopher Woods
Original Assignee
Phasebio Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phasebio Pharmaceuticals Inc filed Critical Phasebio Pharmaceuticals Inc
Publication of SG11201402661TA publication Critical patent/SG11201402661TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
SG11201402661TA 2011-11-28 2012-11-28 Therapeutic agents comprising insulin amino acid sequences SG11201402661TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161563985P 2011-11-28 2011-11-28
PCT/US2012/066795 WO2013082116A1 (fr) 2011-11-28 2012-11-28 Agents thérapeutiques comprenant des séquences d'acides aminés d'insuline

Publications (1)

Publication Number Publication Date
SG11201402661TA true SG11201402661TA (en) 2014-08-28

Family

ID=48536000

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201402661TA SG11201402661TA (en) 2011-11-28 2012-11-28 Therapeutic agents comprising insulin amino acid sequences

Country Status (14)

Country Link
US (2) US20130150291A1 (fr)
EP (1) EP2785367A4 (fr)
JP (1) JP2014534265A (fr)
KR (1) KR20140103985A (fr)
CN (1) CN104080473A (fr)
AU (1) AU2012346058A1 (fr)
BR (1) BR112014012789A2 (fr)
CA (1) CA2856967A1 (fr)
HK (1) HK1202067A1 (fr)
IL (1) IL232781A0 (fr)
MX (1) MX2014006391A (fr)
RU (1) RU2014126244A (fr)
SG (1) SG11201402661TA (fr)
WO (1) WO2013082116A1 (fr)

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US8841255B2 (en) 2005-12-20 2014-09-23 Duke University Therapeutic agents comprising fusions of vasoactive intestinal peptide and elastic peptides
US20130172274A1 (en) 2005-12-20 2013-07-04 Duke University Methods and compositions for delivering active agents with enhanced pharmacological properties
EP2926825A1 (fr) 2008-06-27 2015-10-07 Duke University Agents thérapeutiques comprenant des peptides de type élastine
US9561262B2 (en) 2011-06-06 2017-02-07 Phasebio Pharmaceuticals, Inc. Use of modified vasoactive intestinal peptides in the treatment of hypertension
WO2014081849A1 (fr) 2012-11-20 2014-05-30 Phasebio Pharmaceuticals, Inc. Formulations de principes actifs pour une libération prolongée
US20150361154A1 (en) * 2013-01-15 2015-12-17 Phasebio Pharmaceuticals, Inc. Therapeutic agents, compositions, and methods for glycemic control
EP3139949B1 (fr) 2014-05-08 2020-07-29 Phasebio Pharmaceuticals, Inc. Compositions comprenant un protéine de fusion de vip-elp pour l'utilisation dans le traitement de la fibrose kystique
EP3220936A4 (fr) * 2014-11-21 2018-08-22 Phasebio Pharmaceuticals, Inc. Protéines de fusion elp pour libération contrôlée et prolongée
JP6824888B2 (ja) 2015-02-09 2021-02-03 フェーズバイオ ファーマシューティカルズ,インコーポレイテッド 筋肉の疾患および障害を治療するための方法および組成物
TW201718627A (zh) 2015-06-11 2017-06-01 梅茲製藥有限兩合公司 重組梭菌神經毒素及其使用與形成方法、包括其之醫藥組合物及對應其之前驅物、編碼前驅物之核酸序列及其獲得方法與前驅物之形成方法、載體與包括核酸序列之重組宿主細胞
EP3124495A1 (fr) * 2015-07-31 2017-02-01 Centre National de la Recherche Scientifique (C.N.R.S.) Dérivés de polypeptides de type élastine et leurs utilisations
US11458205B2 (en) 2015-08-04 2022-10-04 Duke University Genetically encoded intrinsically disordered stealth polymers for delivery and methods of using same
CN105061566A (zh) * 2015-09-05 2015-11-18 苏州普罗达生物科技有限公司 拟胰岛素多肽及其应用
CN108473548A (zh) * 2015-09-24 2018-08-31 韩美药品股份有限公司 胰岛素生产方法
KR101815080B1 (ko) * 2015-11-03 2018-01-04 재단법인대구경북과학기술원 췌장소도세포 및 엘라스틴 유사 인공 세포외 기질을 포함하는 당뇨병 치료용 약학적 조성물
US11752213B2 (en) 2015-12-21 2023-09-12 Duke University Surfaces having reduced non-specific binding and antigenicity
AU2017227978B2 (en) 2016-03-02 2022-03-10 Merz Pharma Gmbh & Co. Kgaa Composition comprising botulinum toxin
WO2017189860A1 (fr) 2016-04-27 2017-11-02 The Regents Of The University Of California Préparation de résidus fonctionnels d'homocystéine dans des polypeptides et des peptides
AU2017261216B2 (en) * 2016-05-06 2023-08-03 Immunoforge Co., Ltd. ELP fusion proteins for controlled and sustained release
US11467156B2 (en) 2016-06-01 2022-10-11 Duke University Nonfouling biosensors
KR20190064600A (ko) 2016-09-23 2019-06-10 듀크 유니버시티 Lcst 거동을 갖는 비구조화된 비-반복적 폴리펩티드
US11220467B2 (en) 2017-01-11 2022-01-11 Recycle Track Systems, Inc. Indoor food waste fermentation and recycling process
WO2018132732A1 (fr) 2017-01-12 2018-07-19 Duke University Biomatériaux hybrides lipide-polypeptide génétiquement codés qui offrent un auto-assemblage hiérarchique déclenché par la température
WO2018213320A1 (fr) 2017-05-15 2018-11-22 Duke University Production recombinante de matériaux hybrides lipidiques-biopolymères qui s'auto-assemblent et encapsulent des agents
US11952601B2 (en) 2017-06-20 2024-04-09 Merz Pharma Gmbh & Co. Kgaa Recombinant botulinum toxin with increased duration of effect
WO2019006374A1 (fr) 2017-06-30 2019-01-03 Duke University Ordre et désordre en tant que principe de conception pour des réseaux de biopolymère sensibles à des stimuli
ES2930237T3 (es) 2017-07-06 2022-12-09 Merz Pharma Gmbh & Co Kgaa Neurotoxinas botulínicas recombinantes nuevas con mayor duración de efectos
EP3829622A4 (fr) 2018-08-02 2022-05-11 Duke University Protéines de fusion à double agoniste
KR102456958B1 (ko) * 2019-05-14 2022-10-21 강원대학교 산학협력단 당뇨병성 합병증의 예방 또는 치료용 약제학적 조성물
CN111939244A (zh) 2019-05-14 2020-11-17 阿莫生命科学有限公司 用于预防或治疗糖尿病并发症的药物组合物
US11512314B2 (en) 2019-07-12 2022-11-29 Duke University Amphiphilic polynucleotides
JPWO2021112249A1 (fr) * 2019-12-06 2021-06-10

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Publication number Priority date Publication date Assignee Title
EP1030688B1 (fr) * 1997-11-12 2004-09-29 Alza Corporation Procede d'administration dermale de polypeptides
US7846445B2 (en) * 2005-09-27 2010-12-07 Amunix Operating, Inc. Methods for production of unstructured recombinant polymers and uses thereof
CA2634034A1 (fr) * 2005-12-20 2007-06-28 Duke University Procedes et compositions pour l'administration d'agents actifs a proprietes pharmacologiques ameliorees
JP2009526856A (ja) * 2006-02-15 2009-07-23 イムクローン・リミテッド・ライアビリティ・カンパニー 抗体製剤
CN101616685B (zh) * 2006-03-06 2013-07-24 阿穆尼克斯运营公司 非结构化重组聚合物和其应用
EP2926825A1 (fr) * 2008-06-27 2015-10-07 Duke University Agents thérapeutiques comprenant des peptides de type élastine
WO2010014689A1 (fr) * 2008-07-29 2010-02-04 Phasebio Pharmaceuticals, Inc. Formulations pharmaceutiques comprenant des protéines analogues à de l'élastine
BR112012001988A2 (pt) * 2009-07-31 2017-05-09 Sanofi Aventis Deutschland composição de insulina de ação prolongada
JP5801807B2 (ja) * 2009-08-14 2015-10-28 フェーズバイオ ファーマシューティカルズ,インコーポレイテッド 修飾された血管作動性腸管ペプチド

Also Published As

Publication number Publication date
JP2014534265A (ja) 2014-12-18
HK1202067A1 (en) 2015-09-18
EP2785367A1 (fr) 2014-10-08
KR20140103985A (ko) 2014-08-27
BR112014012789A2 (pt) 2019-09-24
WO2013082116A1 (fr) 2013-06-06
IL232781A0 (en) 2014-07-31
CN104080473A (zh) 2014-10-01
EP2785367A4 (fr) 2015-06-17
RU2014126244A (ru) 2016-01-27
CA2856967A1 (fr) 2013-06-06
US20140364362A1 (en) 2014-12-11
AU2012346058A1 (en) 2014-06-12
MX2014006391A (es) 2014-09-22
US20130150291A1 (en) 2013-06-13

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