SG11201401236XA - Heterocyclic compounds and use thereof as modulators of type iii receptor tyrosine kinases - Google Patents

Heterocyclic compounds and use thereof as modulators of type iii receptor tyrosine kinases

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Publication number
SG11201401236XA
SG11201401236XA SG11201401236XA SG11201401236XA SG11201401236XA SG 11201401236X A SG11201401236X A SG 11201401236XA SG 11201401236X A SG11201401236X A SG 11201401236XA SG 11201401236X A SG11201401236X A SG 11201401236XA SG 11201401236X A SG11201401236X A SG 11201401236XA
Authority
SG
Singapore
Prior art keywords
modulators
type iii
receptor tyrosine
heterocyclic compounds
tyrosine kinases
Prior art date
Application number
SG11201401236XA
Other languages
English (en)
Inventor
Michael J Hadd
Michael D Hocker
Mark W Holladay
Gang Liu
Martin W Rowbottom
Shimin Xu
Original Assignee
Ambit Biosciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ambit Biosciences Corp filed Critical Ambit Biosciences Corp
Publication of SG11201401236XA publication Critical patent/SG11201401236XA/en

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/423—Oxazoles condensed with carbocyclic rings
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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