SG10202111361TA - Treatment of alopecia areata - Google Patents

Treatment of alopecia areata

Info

Publication number
SG10202111361TA
SG10202111361TA SG10202111361TA SG10202111361TA SG10202111361TA SG 10202111361T A SG10202111361T A SG 10202111361TA SG 10202111361T A SG10202111361T A SG 10202111361TA SG 10202111361T A SG10202111361T A SG 10202111361TA SG 10202111361T A SG10202111361T A SG 10202111361TA
Authority
SG
Singapore
Prior art keywords
clause
compound
oxopropanenitrile
octan
pyrrolo
Prior art date
Application number
SG10202111361TA
Other languages
English (en)
Inventor
Michael Sierra
Tord Labuda
Atsuo Tanimoto
Yuichi Shinozaki
Original Assignee
Leo Pharma As
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2015190849A external-priority patent/JP2017066061A/ja
Application filed by Leo Pharma As, Japan Tobacco Inc filed Critical Leo Pharma As
Publication of SG10202111361TA publication Critical patent/SG10202111361TA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG10202111361TA 2015-09-24 2016-09-22 Treatment of alopecia areata SG10202111361TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15186644 2015-09-24
JP2015190849A JP2017066061A (ja) 2015-09-29 2015-09-29 円形脱毛症治療剤

Publications (1)

Publication Number Publication Date
SG10202111361TA true SG10202111361TA (en) 2021-12-30

Family

ID=57047187

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10202111361TA SG10202111361TA (en) 2015-09-24 2016-09-22 Treatment of alopecia areata

Country Status (27)

Country Link
US (3) US20180263986A1 (https=)
EP (1) EP3352734B1 (https=)
JP (1) JP6776345B2 (https=)
KR (1) KR102728341B1 (https=)
CN (1) CN108135834B (https=)
AU (3) AU2016325388A1 (https=)
BR (1) BR112018005771B1 (https=)
CA (1) CA2998972A1 (https=)
CY (1) CY1122837T1 (https=)
DK (1) DK3352734T3 (https=)
ES (1) ES2779762T3 (https=)
HR (1) HRP20200472T1 (https=)
HU (1) HUE049052T2 (https=)
IL (3) IL298520A (https=)
LT (1) LT3352734T (https=)
MX (1) MX375024B (https=)
MY (1) MY196541A (https=)
PL (1) PL3352734T3 (https=)
PT (1) PT3352734T (https=)
RS (1) RS60365B1 (https=)
RU (1) RU2754997C2 (https=)
SG (1) SG10202111361TA (https=)
SI (1) SI3352734T1 (https=)
TW (1) TWI720022B (https=)
UA (1) UA124192C2 (https=)
WO (1) WO2017050891A1 (https=)
ZA (1) ZA201801722B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119367282A (zh) * 2019-12-27 2025-01-28 乐敦制药株式会社 水性组合物
WO2023029943A1 (zh) * 2021-09-03 2023-03-09 星药科技(北京)有限公司 一种芳杂环化合物及其制备方法和用途
WO2023202989A1 (en) 2022-04-20 2023-10-26 Leo Pharma A/S Treatment of frontal fibrosing alopecia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI466885B (zh) * 2009-07-31 2015-01-01 Japan Tobacco Inc 含氮螺環化合物及其醫藥用途
US8637569B2 (en) * 2009-10-22 2014-01-28 Api Genesis, Llc Methods of increasing solubility of poorly soluble compounds and methods of making and using formulations of such compounds
US20140343034A1 (en) * 2013-04-25 2014-11-20 Japan Tobacco Inc. Skin barrier function improving agent
JP6427497B2 (ja) * 2013-10-21 2018-11-21 日本たばこ産業株式会社 眼疾患の治療剤又は予防剤

Also Published As

Publication number Publication date
PT3352734T (pt) 2020-03-31
CN108135834A (zh) 2018-06-08
RU2018114922A (ru) 2019-10-28
JP2018528238A (ja) 2018-09-27
LT3352734T (lt) 2020-04-10
PL3352734T3 (pl) 2020-08-24
RS60365B1 (sr) 2020-07-31
IL312861A (en) 2024-07-01
HK1257770A1 (en) 2019-10-25
AU2024204716A1 (en) 2024-07-25
RU2018114922A3 (https=) 2019-12-11
KR102728341B1 (ko) 2024-11-11
MY196541A (en) 2023-04-19
TWI720022B (zh) 2021-03-01
CA2998972A1 (en) 2017-03-30
DK3352734T3 (da) 2020-03-30
AU2022202508A1 (en) 2022-05-12
HRP20200472T1 (hr) 2020-09-18
EP3352734B1 (en) 2020-01-15
US20220088020A1 (en) 2022-03-24
RU2754997C2 (ru) 2021-09-08
ES2779762T3 (es) 2020-08-19
MX375024B (es) 2025-03-06
US20180263986A1 (en) 2018-09-20
AU2016325388A1 (en) 2018-03-29
BR112018005771B1 (pt) 2023-12-05
HUE049052T2 (hu) 2020-09-28
UA124192C2 (uk) 2021-08-04
BR112018005771A2 (pt) 2018-10-09
NZ740690A (en) 2024-11-29
WO2017050891A1 (en) 2017-03-30
MX2018003332A (es) 2018-08-16
SI3352734T1 (sl) 2020-07-31
CN108135834B (zh) 2021-07-27
IL257918A (en) 2018-05-31
ZA201801722B (en) 2025-06-25
KR20180054767A (ko) 2018-05-24
US20240398809A1 (en) 2024-12-05
IL298520A (en) 2023-01-01
TW201717955A (zh) 2017-06-01
CY1122837T1 (el) 2021-05-05
JP6776345B2 (ja) 2020-10-28
EP3352734A1 (en) 2018-08-01

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