SG10202102509TA - Micrornas as biomarkers for endometriosis - Google Patents

Micrornas as biomarkers for endometriosis

Info

Publication number
SG10202102509TA
SG10202102509TA SG10202102509TA SG10202102509TA SG10202102509TA SG 10202102509T A SG10202102509T A SG 10202102509TA SG 10202102509T A SG10202102509T A SG 10202102509TA SG 10202102509T A SG10202102509T A SG 10202102509TA SG 10202102509T A SG10202102509T A SG 10202102509TA
Authority
SG
Singapore
Prior art keywords
micrornas
endometriosis
biomarkers
Prior art date
Application number
SG10202102509TA
Other languages
English (en)
Inventor
Hugh Taylor
Original Assignee
Univ Yale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Yale filed Critical Univ Yale
Publication of SG10202102509TA publication Critical patent/SG10202102509TA/en

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/36Gynecology or obstetrics
    • G01N2800/364Endometriosis, i.e. non-malignant disorder in which functioning endometrial tissue is present outside the uterine cavity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
SG10202102509TA 2016-08-30 2017-08-30 Micrornas as biomarkers for endometriosis SG10202102509TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662381130P 2016-08-30 2016-08-30

Publications (1)

Publication Number Publication Date
SG10202102509TA true SG10202102509TA (en) 2021-04-29

Family

ID=61301726

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10202102509TA SG10202102509TA (en) 2016-08-30 2017-08-30 Micrornas as biomarkers for endometriosis
SG11201901834WA SG11201901834WA (en) 2016-08-30 2017-08-30 Micrornas as biomarkers for endometriosis

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201901834WA SG11201901834WA (en) 2016-08-30 2017-08-30 Micrornas as biomarkers for endometriosis

Country Status (11)

Country Link
US (3) US10982282B2 (https=)
EP (1) EP3506912B1 (https=)
JP (2) JP2019528081A (https=)
KR (1) KR20190057305A (https=)
CN (1) CN109890394A (https=)
AU (1) AU2017319325A1 (https=)
BR (1) BR112019004075A2 (https=)
CA (1) CA3035429A1 (https=)
MX (1) MX2019002425A (https=)
SG (2) SG10202102509TA (https=)
WO (1) WO2018044979A1 (https=)

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* Cited by examiner, † Cited by third party
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EP3122905B1 (en) 2014-03-27 2020-09-09 Yale University Circulating micrornas as biomarkers for endometriosis
WO2018044979A1 (en) 2016-08-30 2018-03-08 Yale University Micrornas as biomarkers for endometriosis
AU2018324040A1 (en) * 2017-08-30 2020-03-05 Dot Laboratories, Inc. Methods and compositions for detecting and treating endometriosis
EP3820483A4 (en) * 2018-07-13 2023-03-01 Yale University COMPOSITIONS AND METHODS FOR THE TREATMENT OF ENDOMETRIOSIS
KR102089559B1 (ko) 2018-08-31 2020-03-16 차의과학대학교 산학협력단 난소의 fsh에 대한 반응성의 진단 또는 예측용 바이오마커 및 이의 용도
US11315660B2 (en) 2018-10-31 2022-04-26 Dot Laboratories, Inc. Method of detecting and treating endometriosis in a female subject
CA3118133A1 (en) * 2018-10-31 2020-05-07 Yale University A quantitative algorithm for endometriosis
WO2020146544A1 (en) * 2019-01-09 2020-07-16 Research Institute At Nationwide Children's Hospital A novel method for monitoring endometriosis and associated disorders
JPWO2020179895A1 (https=) 2019-03-07 2020-09-10
ES2787725A1 (es) * 2019-04-15 2020-10-16 Univ Granada Metodo de obtencion de datos utiles para diagnosticar telangiectasia hemorragica hereditaria
CN110144394A (zh) * 2019-04-18 2019-08-20 辽宁省肿瘤医院 一种子宫内膜异位症诊断、预后标志物及其应用
WO2021013785A1 (en) * 2019-07-22 2021-01-28 F. Hoffmann-La Roche Ag S100a9 as blood biomarker for the non-invasive diagnosis of endometriosis
WO2021013784A1 (en) * 2019-07-22 2021-01-28 F. Hoffmann-La Roche Ag S100a8 as blood biomarker for the non-invasive diagnosis of endometriosis
JP7315780B2 (ja) * 2019-07-22 2023-07-26 エフ. ホフマン-ラ ロシュ アーゲー 子宮内膜症の非侵襲的診断のための血液バイオマーカーとしてのサブスタンスp
US11965879B2 (en) 2019-08-23 2024-04-23 Mcmaster University Method for diagnosing and assessing endometriosis
KR102242639B1 (ko) * 2020-01-28 2021-04-21 고려대학교 산학협력단 간 섬유화 진단용 바이오마커 miRNA4668-5p
KR102316507B1 (ko) * 2020-02-28 2021-10-22 차의과학대학교 산학협력단 난소 예비력 바이오마커 및 이의 용도
CN111909997B (zh) * 2020-09-09 2021-09-28 上海交通大学 miRNA标志物在制备奥氮平治疗精神分裂症疗效评估方面的产品中的应用及试剂盒
JP2022063860A (ja) * 2020-10-12 2022-04-22 学校法人近畿大学 ホウ素化合物およびその製造方法
KR102940037B1 (ko) * 2022-12-06 2026-03-16 연세대학교 산학협력단 자궁내막증 진단용 조성물

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WO2009143181A2 (en) 2008-05-19 2009-11-26 The Regents Of The University Of California Micro-rna profile in human saliva and its use for detection of oral cancer
WO2011109440A1 (en) * 2010-03-01 2011-09-09 Caris Life Sciences Luxembourg Holdings Biomarkers for theranostics
GB2463401B (en) 2008-11-12 2014-01-29 Caris Life Sciences Luxembourg Holdings S A R L Characterizing prostate disorders by analysis of microvesicles
DK2416789T3 (en) 2009-04-07 2017-10-09 Velin-Pharma As Method and apparatus for treating diseases associated with inflammation or unwanted activation of the immune system
JP2014513521A (ja) * 2011-01-26 2014-06-05 セファイド 肺癌を検出する方法
EP2675914A1 (en) 2011-02-18 2013-12-25 Yale University, Inc. The kras-variant and endometriosis
FR2984358A1 (fr) 2011-12-16 2013-06-21 Genethon Methodes pour le diagnostic de dystrophies musculaires
WO2013148151A1 (en) 2012-03-29 2013-10-03 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Plasma microribonucleic acids as biomarkers for endometriosis and endometriosis-associated ovarian cancer
WO2015050875A1 (en) 2013-10-01 2015-04-09 The Regents Of The University Of California Endometriosis classifier
JP6930832B2 (ja) * 2013-11-18 2021-09-01 ディアミール, エルエルシーDiamir, Llc パーキンソン病(PD)の検出およびモニタリングのための、体液からのmiRNAを使用する方法
GB201403489D0 (en) 2014-02-27 2014-04-16 Univ London Queen Mary Biomarkers for endometriosis
US9650676B2 (en) 2014-03-19 2017-05-16 University Of South Carolina Leukocyte MicroRNAS for use in diagnosis and treatment of endometriosis
EP3122905B1 (en) * 2014-03-27 2020-09-09 Yale University Circulating micrornas as biomarkers for endometriosis
EP2924126B1 (en) * 2014-03-28 2018-04-18 Tervisetehnoloogiate Arenduskeskus AS Method for using microRNA (miRNA) for detection of endometriosis
GB201603967D0 (en) * 2016-03-08 2016-04-20 Univ Birmingham Biomarkers of traumatic brain injury
WO2018044979A1 (en) 2016-08-30 2018-03-08 Yale University Micrornas as biomarkers for endometriosis
AU2018324040A1 (en) 2017-08-30 2020-03-05 Dot Laboratories, Inc. Methods and compositions for detecting and treating endometriosis
CA3118133A1 (en) 2018-10-31 2020-05-07 Yale University A quantitative algorithm for endometriosis
US11315660B2 (en) 2018-10-31 2022-04-26 Dot Laboratories, Inc. Method of detecting and treating endometriosis in a female subject
WO2020223238A1 (en) 2019-04-29 2020-11-05 Yale University Classifiers for detection of endometriosis

Also Published As

Publication number Publication date
EP3506912B1 (en) 2024-04-03
US12077803B2 (en) 2024-09-03
SG11201901834WA (en) 2019-03-28
JP2019528081A (ja) 2019-10-10
WO2018044979A1 (en) 2018-03-08
US20220049312A1 (en) 2022-02-17
MX2019002425A (es) 2019-08-16
CA3035429A1 (en) 2018-03-08
CN109890394A (zh) 2019-06-14
US11220713B2 (en) 2022-01-11
EP3506912A1 (en) 2019-07-10
US20210180134A1 (en) 2021-06-17
JP2022188086A (ja) 2022-12-20
AU2017319325A1 (en) 2019-03-21
KR20190057305A (ko) 2019-05-28
BR112019004075A2 (pt) 2019-05-28
EP3506912A4 (en) 2020-08-19
US10982282B2 (en) 2021-04-20
US20190276893A1 (en) 2019-09-12

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