SG10201913649TA - Treatment of epithelial cysts by intracystic injection of antineoplastic particles - Google Patents

Treatment of epithelial cysts by intracystic injection of antineoplastic particles

Info

Publication number
SG10201913649TA
SG10201913649TA SG10201913649TA SG10201913649TA SG10201913649TA SG 10201913649T A SG10201913649T A SG 10201913649TA SG 10201913649T A SG10201913649T A SG 10201913649TA SG 10201913649T A SG10201913649T A SG 10201913649TA SG 10201913649T A SG10201913649T A SG 10201913649TA
Authority
SG
Singapore
Prior art keywords
treatment
antineoplastic particles
epithelial cysts
intracystic injection
intracystic
Prior art date
Application number
SG10201913649TA
Other languages
English (en)
Inventor
Gere Dizerega
Michael Baltezor
Charles Decedue
Sam Campbell
Matthew Mcclorey
Marc Iacobucci
Holly Maulhardt
Original Assignee
Crititech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crititech Inc filed Critical Crititech Inc
Publication of SG10201913649TA publication Critical patent/SG10201913649TA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • A61B8/0833Detecting organic movements or changes, e.g. tumours, cysts, swellings involving detecting or locating foreign bodies or organic structures
    • A61B8/0841Detecting organic movements or changes, e.g. tumours, cysts, swellings involving detecting or locating foreign bodies or organic structures for locating instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/12Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG10201913649TA 2017-06-09 2018-06-08 Treatment of epithelial cysts by intracystic injection of antineoplastic particles SG10201913649TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201762517711P 2017-06-09 2017-06-09

Publications (1)

Publication Number Publication Date
SG10201913649TA true SG10201913649TA (en) 2020-03-30

Family

ID=62779068

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201913649TA SG10201913649TA (en) 2017-06-09 2018-06-08 Treatment of epithelial cysts by intracystic injection of antineoplastic particles
SG11201909840T SG11201909840TA (en) 2017-06-09 2018-06-08 Treatment of epithelial cysts by intracystic injection of antineoplastic particles

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201909840T SG11201909840TA (en) 2017-06-09 2018-06-08 Treatment of epithelial cysts by intracystic injection of antineoplastic particles

Country Status (11)

Country Link
US (4) US20190254957A1 (fr)
EP (1) EP3615145B1 (fr)
JP (1) JP2020523285A (fr)
KR (1) KR20200014279A (fr)
CN (1) CN110730679A (fr)
AU (1) AU2018279634A1 (fr)
BR (1) BR112019023948A2 (fr)
CA (1) CA3063420A1 (fr)
RU (1) RU2019134145A (fr)
SG (2) SG10201913649TA (fr)
WO (1) WO2018227037A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3302423B1 (fr) 2015-06-04 2022-05-25 Crititech, Inc. Système de production de particules et dispositif de collecte de particules
KR102490665B1 (ko) 2016-04-04 2023-01-27 크리티테크, 인크. 고형 종양의 치료 방법
WO2018227037A1 (fr) 2017-06-09 2018-12-13 Crititech, Inc. Traitement de kystes épithéliaux par injection intrakystique de particules antinéoplasiques
CN115919815A (zh) 2017-06-14 2023-04-07 克里蒂泰克公司 治疗肺部疾病的方法
SG11202001802YA (en) 2017-10-03 2020-03-30 Crititech Inc Local delivery of antineoplastic particles in combination with systemic delivery of immunotherapeutic agents for the treatment of cancer
KR102526793B1 (ko) * 2021-11-03 2023-04-28 주식회사 에스엔바이오사이언스 입도분포 유지 안정성이 개선된 알부민 결합 탁산 나노입자 제조방법

Family Cites Families (122)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5399363A (en) 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
US6749868B1 (en) 1993-02-22 2004-06-15 American Bioscience, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
US5886026A (en) 1993-07-19 1999-03-23 Angiotech Pharmaceuticals Inc. Anti-angiogenic compositions and methods of use
GB9413202D0 (en) 1994-06-30 1994-08-24 Univ Bradford Method and apparatus for the formation of particles
US5626862A (en) 1994-08-02 1997-05-06 Massachusetts Institute Of Technology Controlled local delivery of chemotherapeutic agents for treating solid tumors
US5874481A (en) 1995-06-07 1999-02-23 Alliance Pharmaceutical Corp. Fluorochemical solutions for the delivery of lipophilic pharmaceutical agents
US5874029A (en) 1996-10-09 1999-02-23 The University Of Kansas Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent
US5833891A (en) 1996-10-09 1998-11-10 The University Of Kansas Methods for a particle precipitation and coating using near-critical and supercritical antisolvents
US6495579B1 (en) 1996-12-02 2002-12-17 Angiotech Pharmaceuticals, Inc. Method for treating multiple sclerosis
AU741439B2 (en) 1996-12-30 2001-11-29 Battelle Memorial Institute Formulation and method for treating neoplasms by inhalation
IL133672A0 (en) 1997-06-27 2001-04-30 Vivorx Pharmaceuticals Inc Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
CN101579335B (zh) * 1997-06-27 2016-08-03 阿布拉科斯生物科学有限公司 药剂的制剂及其制备和应用方法
US6117949A (en) 1998-10-01 2000-09-12 Macromed, Inc. Biodegradable low molecular weight triblock poly (lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
JP3418751B2 (ja) 1998-01-22 2003-06-23 参天製薬株式会社 フルオロメトロン懸濁型点眼剤
IL131217A0 (en) 1998-03-10 2001-01-28 Napro Biotherapeutics Inc Novel methods and compositions for delivery of taxanes
US6221153B1 (en) 1998-06-09 2001-04-24 Trevor Percival Castor Method for producing large crystals of complex molecules
US7521068B2 (en) 1998-11-12 2009-04-21 Elan Pharma International Ltd. Dry powder aerosols of nanoparticulate drugs
US6113795A (en) 1998-11-17 2000-09-05 The University Of Kansas Process and apparatus for size selective separation of micro- and nano-particles
CA2351947C (fr) 1998-11-25 2008-10-21 Universitatsklinikum Freiburg Hyperforine s'utilisant comme cytostatique et pommade ou creme a base d'hyperforine comme forme galenique d'application
US6537585B1 (en) 1999-03-26 2003-03-25 Guilford Pharmaceuticals, Inc. Methods and compositions for treating solid tumors
US7217735B1 (en) 1999-04-09 2007-05-15 Au Jessie L-S Methods and compositions for enhancing delivery of therapeutic agents to tissues
KR100752000B1 (ko) 1999-05-27 2007-08-28 아쿠스피어 인코포레이티드. 다공성 약물 매트릭스의 제조방법
US6610317B2 (en) 1999-05-27 2003-08-26 Acusphere, Inc. Porous paclitaxel matrices and methods of manufacture thereof
US6858199B1 (en) 2000-06-09 2005-02-22 Advanced Inhalation Research, Inc. High efficient delivery of a large therapeutic mass aerosol
US6616849B1 (en) 1999-08-25 2003-09-09 Shimadzu Corporation Method of and system for continuously processing liquid materials, and the product processed thereby
JP2003513756A (ja) 1999-11-12 2003-04-15 アンジオテック ファーマシューティカルズ,インコーポレイテッド 放射性治療と細胞周期インヒビターとの組合せの組成物
US6620351B2 (en) 2000-05-24 2003-09-16 Auburn University Method of forming nanoparticles and microparticles of controllable size using supercritical fluids with enhanced mass transfer
US6562952B1 (en) 2000-10-31 2003-05-13 The University Of Kansas Precipitation of proteins from organic solutions
US20020081339A1 (en) 2000-12-22 2002-06-27 Philippe Menei Treatment of inoperable tumors by stereotactic injection of microspheres
WO2002087563A2 (fr) 2001-05-01 2002-11-07 Angiotech Pharmaceuticals Inc. Compositions et procedes pour le traitement d'etats inflammatoires par des proteines ou polysaccharides contenant des agents anti-microtubules
PT1401563E (pt) 2001-07-02 2006-08-31 Micro & Nano Materials Sagl Processo para a producao de micro e/ou nano particulas
US20030054042A1 (en) 2001-09-14 2003-03-20 Elaine Liversidge Stabilization of chemical compounds using nanoparticulate formulations
US20030134810A1 (en) * 2001-10-09 2003-07-17 Chris Springate Methods and compositions comprising biocompatible materials useful for the administration of therapeutic agents
US20030087837A1 (en) 2001-10-15 2003-05-08 Jonas Jeffrey M. Compositions and methods for delivery of poorly water soluble drugs and methods of treatment
CA2465779A1 (fr) 2001-11-20 2003-05-30 Advanced Inhalation Research, Inc. Compositions destinees a la liberation de produits a action continue
US7138136B2 (en) 2002-03-05 2006-11-21 Cleveland State University Agglomerated particles for aerosol drug delivery
AU2003230691A1 (en) 2002-03-20 2003-10-08 Elan Pharma International Ltd. Nanoparticulate compositions of angiogenesis inhibitors
EP1501483A2 (fr) 2002-04-25 2005-02-02 Nektar Therapeutics UK Ltd Materiaux particulaires
EA200401250A1 (ru) 2002-04-26 2005-06-30 Тева Фармасьютикал Индастриес Лтд. Фармацевтические композиции на основе микрочастиц для внутриопухолевого введения
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
CN1255394C (zh) 2002-06-24 2006-05-10 成都思摩纳米技术有限公司 紫杉醇纳米微粒的制备方法及应用
KR100573289B1 (ko) 2002-07-20 2006-04-24 대화제약 주식회사 방광내 투여를 통한 방광암치료용 파클리탁셀 조성물 및그의 제조 방법
WO2004098570A1 (fr) 2002-10-30 2004-11-18 Spherics, Inc. Agents bioactifs nanoparticulaires
KR100508518B1 (ko) 2002-11-13 2005-08-17 한미약품 주식회사 초임계유체 공정을 이용한 파클리탁셀 고체분산체의 제조방법 및 이 방법으로 제조된 파클리탁셀 고체분산체
CN103405405A (zh) 2002-12-09 2013-11-27 阿布拉西斯生物科学有限责任公司 组合物和传递药剂的方法
US7455797B2 (en) 2003-02-28 2008-11-25 Ferro Corporation Method and apparatus for producing particles using supercritical fluid
CA2520475C (fr) 2003-04-03 2012-10-09 Jessie L.-S. Au Particules a charge medicamenteuse ciblant les tumeurs
US20060147535A1 (en) 2003-04-16 2006-07-06 Poongunran Muthukumaran Methods for and compositions of anticancer medicaments
US20050059613A1 (en) 2003-07-08 2005-03-17 Bahram Memarzadeh Compositions and methods for the enhanced uptake of therapeutic agents through the bladder epithelium
US8021831B2 (en) 2003-08-25 2011-09-20 Board Of Regents, The University Of Texas System Taxane chemosensitivity prediction test
JP2007001865A (ja) 2003-09-16 2007-01-11 Ltt Bio-Pharma Co Ltd 脂溶性薬物封入微粒子、その製造法およびそれを含有する製剤
AU2004283464B8 (en) 2003-10-15 2011-04-14 Syncore Biotechnology Co., Ltd Method of administering cationic liposomes comprising an active drug
US7208106B2 (en) 2003-10-24 2007-04-24 Ferro Corporation Method of forming particles
ES2366646T3 (es) 2003-11-05 2011-10-24 Elan Pharma International Limited Composiciones en forma de nanopartículas que tienen un péptido como estabilizante superficial.
GB0402963D0 (en) 2004-02-11 2004-03-17 Univ Nottingham Counter current mixing device for two different fluids
US8043631B2 (en) 2004-04-02 2011-10-25 Au Jessie L S Tumor targeting drug-loaded particles
US7833444B2 (en) 2004-10-29 2010-11-16 Nara Machinery Co., Ltd. Fine particle granulation method
US20060159712A1 (en) 2004-12-14 2006-07-20 Transave, Inc. Lipid particles comprising bioactive agents, methods of preparing and uses thereof
ES2265262B1 (es) 2005-01-31 2008-03-01 Activery Biotech, S.L.(Titular Al 50%) Procedimiento para la obtencion de sistemas micro- y nanodispersos.
US8735394B2 (en) 2005-02-18 2014-05-27 Abraxis Bioscience, Llc Combinations and modes of administration of therapeutic agents and combination therapy
WO2006091780A2 (fr) 2005-02-24 2006-08-31 Elan Pharma International Limited Preparations de nanoparticules de docetaxel et de ses analogues
US7872050B2 (en) 2005-03-14 2011-01-18 Yaupon Therapeutics Inc. Stabilized compositions of volatile alkylating agents and methods of using thereof
PL1865924T3 (pl) 2005-03-31 2016-06-30 Lidds Ab Sposób leczenia chorób gruczołu krokowego oparty na miejscowym dostarczaniu substancji czynnych
CN1923189A (zh) 2005-08-30 2007-03-07 孔庆忠 一种紫杉碱类抗癌药物的缓释注射剂
KR101643416B1 (ko) * 2005-08-31 2016-07-27 아브락시스 바이오사이언스, 엘엘씨 증가된 안정성을 가진 수 난용성 약물의 조성물 및 제조방법
EA013089B1 (ru) 2005-12-11 2010-02-26 Скф Технолоджис А/С Получение наноразмерных материалов
US8906392B2 (en) 2005-12-16 2014-12-09 University Of Kansas Nanocluster compositions and methods
AR054215A1 (es) 2006-01-20 2007-06-13 Eriochem Sa Una formulacion farmaceutica de un taxano, una composicion solida de un taxano liofilizado a partir de una solucion de acido acetico, un procedimiento para la preparacion de dicha composicion solida de un taxano, una composicion solubilizante de un taxano liofilizado, y un conjunto de elementos (kit
CN101336899A (zh) 2006-01-25 2009-01-07 济南帅华医药科技有限公司 含紫杉烷的抗癌缓释注射剂
CN101431984B (zh) 2006-03-14 2013-07-10 利德斯股份公司 生物可吸收性的控释组合物
US7744923B2 (en) 2006-10-11 2010-06-29 Crititech, Inc. Method for precipitation of small medicament particles into use containers
TWI405590B (zh) 2007-04-06 2013-08-21 Activus Pharma Co Ltd 微粉碎化有機化合物粒子之製法
CA2686736A1 (fr) 2007-05-03 2008-11-13 Abraxis Bioscience, Llc Compositions de nanoparticules comprenant de la rapamycine pour le traitement de l'hypertension pulmonaire
US20100197944A1 (en) 2007-07-04 2010-08-05 Dr. Reddy's Laboratories Limited Docetaxel process and polymorphs
CN101129338A (zh) 2007-08-27 2008-02-27 四川大学 超临界流体新技术微细化抗癌药物紫杉醇
MX2010009670A (es) 2008-03-06 2010-09-22 Nitto Denko Corp Conjugados de paclitaxel polimericos y metodos para tratamiento de cancer.
KR101455446B1 (ko) 2008-09-19 2014-10-27 액티버스 파마 컴퍼니 리미티드 의료용 복합 유기 화합물 분체, 그 제조 방법 및 현탁액
WO2010063630A2 (fr) * 2008-12-02 2010-06-10 Biocompatibles Uk Limited Traitement de tumeur du pancréas
PT104693B (pt) 2009-07-27 2011-11-24 Univ Lisboa Nanopartículas lipídicas semi-sólidas contendo um agente antineoplásico e seu processo de preparação
MX2012002365A (es) 2009-08-24 2012-07-17 Baylor College Medicine Generación de lineas de linfocitos t citotóxicos con especificidad contra antígenos tumorales multiples o virus múltiples.
CN101829061A (zh) 2010-05-14 2010-09-15 无锡纳生生物科技有限公司 一种紫杉醇纳米颗粒组合物及其制备方法
SG186109A1 (en) 2010-06-02 2013-01-30 Abraxis Bioscience Llc Methods of treating bladder cancer
BR112013006861A2 (pt) 2010-09-21 2019-07-02 Cristal Delivery B V ligante para ser utilizado em um sistema de liberação de fármaco, composto compreendendo um ligante, uso de um composto, sistema de liberação controlada e método para preparar um sistema de liberação controlada
JP2014504260A (ja) 2010-10-15 2014-02-20 グラクソ グループ リミテッド 集合ナノ粒子状薬物製剤、その製造及び使用
US20120177910A1 (en) 2011-01-11 2012-07-12 Boston Scientific Scimed, Inc. Coated Medical Devices
CA2833413C (fr) 2011-04-20 2020-09-22 The University Of Sydney Procede pour le traitement d'une tumeur solide
US20140154269A1 (en) 2011-04-26 2014-06-05 The Methodist Hospital Research Institute Targeted nanovectors and their use for treatment of brain tumors
JP5932993B2 (ja) 2011-06-17 2016-06-08 バーグ エルエルシー 吸入可能な医薬組成物
US10632131B2 (en) 2011-06-27 2020-04-28 Cristal Delivery B.V. Controlled release system
FR2980683B1 (fr) 2011-09-30 2014-11-21 Univ Paris Curie Dispositif de guidage d'un instrument medical insere dans une voie naturelle ou une voie artificielle d'un patient
CN102488682A (zh) 2011-11-22 2012-06-13 四川九章生物化工科技发展有限公司 绿原酸的抗癌新用途
WO2013166487A1 (fr) 2012-05-04 2013-11-07 Yale University Nanosupports à pénétration élevée pour le traitement d'une maladie du snc
TW201408304A (zh) 2012-08-31 2014-03-01 Cathay General Hospital 一種合併抗癌藥物及荷爾蒙之抗腎細胞癌藥物及其製造方法
US9511046B2 (en) 2013-01-11 2016-12-06 Abraxis Bioscience, Llc Methods of treating pancreatic cancer
CA2898408C (fr) 2013-02-28 2018-01-02 Pfizer Inc. Stabilite amelioree de compositions liquides nouvelles
US8778181B1 (en) 2013-03-14 2014-07-15 Crititech, Inc. Equipment assembly for and method of processing particles
US9925512B2 (en) 2013-03-14 2018-03-27 Crititech, Inc. Equipment assembly for and method of processing particles
US20140294967A1 (en) 2013-03-28 2014-10-02 Bbs Nanotechnology Llc. Stable nanocomposition comprising paclitaxel, process for the preparation thereof, its use and pharmaceutical compositions containing it
ES2762555T3 (es) 2013-04-10 2020-05-25 Massachusetts Inst Technology Dispositivos y métodos de administración local de fármacos para el tratamiento del cáncer
WO2015055796A1 (fr) 2013-10-16 2015-04-23 Université Libre de Bruxelles Formulations utiles dans le traitement de maladies prolifératives affectant le tractus respiratoire
EP3083686B2 (fr) 2013-12-17 2023-03-22 F. Hoffmann-La Roche AG Procédés de traitement de cancers à l'aide d'antagonistes se liant à l'axe pd-1 et de taxanes
AU2014368898B2 (en) 2013-12-20 2020-06-11 Dana-Farber Cancer Institute, Inc. Combination therapy with neoantigen vaccine
WO2015103005A1 (fr) * 2014-01-03 2015-07-09 Research Institute At Nationwide Children's Hospital Composés amines amphiphiles et leur utilisation en tant qu'agents thérapeutiques et nanosupports
TWI601542B (zh) 2014-04-18 2017-10-11 林信湧 一種用於治療肺癌之吸入式醫藥組成物及其備製方法
WO2015187194A1 (fr) 2014-06-01 2015-12-10 Crititech, Inc. Utilisation de particules de paclitaxel
WO2015191590A2 (fr) 2014-06-09 2015-12-17 Biomed Valley Discoveries, Inc. Polythérapies ciblant des stromas associés à une tumeur ou des cellules tumorales et des microtubules
US10975442B2 (en) 2014-12-19 2021-04-13 Massachusetts Institute Of Technology Molecular biomarkers for cancer immunotherapy
EP3302423B1 (fr) 2015-06-04 2022-05-25 Crititech, Inc. Système de production de particules et dispositif de collecte de particules
WO2017049083A2 (fr) 2015-09-16 2017-03-23 Dfb Soria, Llc Administration de nanoparticules médicamenteuses et leurs méthodes d'utilisation
AU2016326747A1 (en) * 2015-09-25 2018-03-01 Zy Therapeutics Inc. Drug formulation based on particulates comprising polysaccharide-vitamin conjugate
DE202016006620U1 (de) 2015-10-28 2017-04-12 Qass Gmbh Vorrichtungen zum Beobachten eines Magnetfelds eines Materialvolumens
AU2017210031C1 (en) 2016-01-20 2020-11-26 Fate Therapeutics, Inc. Compositions and methods for immune cell modulation in adoptive immunotherapies
KR102490665B1 (ko) 2016-04-04 2023-01-27 크리티테크, 인크. 고형 종양의 치료 방법
CN107281502B (zh) 2016-04-05 2021-05-04 上海市肿瘤研究所 一种复合显影温敏凝胶栓塞剂、制备方法及其应用
WO2017178585A1 (fr) 2016-04-15 2017-10-19 Cellectis Méthode d'ingénierie par inactivation génique de cellules t spécifiquement hypersensibles à un médicament destinées à une utilisation en immunothérapie
US9567399B1 (en) 2016-06-20 2017-02-14 Kymab Limited Antibodies and immunocytokines
CA3035378A1 (fr) 2016-09-01 2018-03-08 Mayo Foundation For Medical Education And Research Compositions d'agents de liaison et de porteuses pd-l1 pour le traitement de cancers
WO2018170207A1 (fr) 2017-03-15 2018-09-20 Dfb Soria, Llc Thérapie topique pour le traitement de kératoses cutanées à l'aide de nanoparticules de taxanes
WO2018170210A1 (fr) 2017-03-15 2018-09-20 Dfb Soria, Llc Thérapie topique pour le traitement de la néoplasie intraépithéliale vulvaire (vin) et des verrues génitales à l'aide de nanoparticules de taxanes
CA3056395C (fr) 2017-03-15 2022-06-28 Dfb Soria, Llc Therapie topique pour le traitement de malignites cutanees au moyen de nanoparticules de taxanes
WO2018227037A1 (fr) 2017-06-09 2018-12-13 Crititech, Inc. Traitement de kystes épithéliaux par injection intrakystique de particules antinéoplasiques
CN115919815A (zh) 2017-06-14 2023-04-07 克里蒂泰克公司 治疗肺部疾病的方法

Also Published As

Publication number Publication date
US11737972B2 (en) 2023-08-29
KR20200014279A (ko) 2020-02-10
US20210259959A1 (en) 2021-08-26
US20190254957A1 (en) 2019-08-22
AU2018279634A1 (en) 2019-10-31
US20230372234A1 (en) 2023-11-23
EP3615145A1 (fr) 2020-03-04
SG11201909840TA (en) 2019-11-28
US20230111288A1 (en) 2023-04-13
JP2020523285A (ja) 2020-08-06
CN110730679A (zh) 2020-01-24
WO2018227037A1 (fr) 2018-12-13
CA3063420A1 (fr) 2018-12-13
BR112019023948A2 (pt) 2020-06-09
EP3615145B1 (fr) 2024-05-15
RU2019134145A (ru) 2021-07-09
US11523983B2 (en) 2022-12-13

Similar Documents

Publication Publication Date Title
GB2569922B (en) Measurement of edema
SG10201913649TA (en) Treatment of epithelial cysts by intracystic injection of antineoplastic particles
EP3658612A4 (fr) Formation de particules comprenant des agents
IL272888A (en) Uses of piperidinyl-indole derivatives
SG11201704626TA (en) Aqueous coating composition and process of making the same
EP3143560C0 (fr) Mise à jour de classifieur adapté à partir de caractéristiques communes
IL254718A0 (en) Continuous production of particles
IL268731A (en) New uses of anti-SIRPG antibodies
IL263050B (en) History of Subtirum
GB201616912D0 (en) Classification of cancer
FR3020865B1 (fr) Chambre annulaire de combustion
EP2948978A4 (fr) Ingénierie des propriétés optiques d'un élément de calcul intégré par implantation d'ions
ZA201906944B (en) Methods of manufacturing of niraparib
SG11201608076RA (en) Process for the production of polyoxymethylene block copolymers
IL269853A (en) Proteins for the treatment of epithelial barrier activity disorders
GB2550170B (en) Improved production of aggregates
GB201609017D0 (en) Characterisation of particles
GB201603883D0 (en) Chamber
AU2017270580B9 (en) Production of rounded salt particles
IL249303B (en) Site-selective modification of polysaccharides and uses
GB201609314D0 (en) Methods of forming compounds
GB201601249D0 (en) Production of manool
IL273543A (en) A new treatment for SMA
EP3139944A4 (fr) Utilisation d'un peptide dans le traitement de maladies associées à une angiogenèse
FI12675U1 (fi) Kerrostalo