SG10201903125QA - Active agent loaded uniform, rigid, spherical, nanoporous calcium phosphate particles and methods of making and using the same - Google Patents

Active agent loaded uniform, rigid, spherical, nanoporous calcium phosphate particles and methods of making and using the same

Info

Publication number
SG10201903125QA
SG10201903125QA SG10201903125QA SG10201903125QA SG10201903125QA SG 10201903125Q A SG10201903125Q A SG 10201903125QA SG 10201903125Q A SG10201903125Q A SG 10201903125QA SG 10201903125Q A SG10201903125Q A SG 10201903125QA SG 10201903125Q A SG10201903125Q A SG 10201903125QA
Authority
SG
Singapore
Prior art keywords
active agent
rigid
spherical
making
methods
Prior art date
Application number
SG10201903125QA
Other languages
English (en)
Inventor
Tetsuro Ogawa
Akira Yamamoto
Original Assignee
Laboratory Skin Care Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratory Skin Care Inc filed Critical Laboratory Skin Care Inc
Publication of SG10201903125QA publication Critical patent/SG10201903125QA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A61K8/0279—Porous; Hollow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24—Phosphorous; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/008—Preparations for oily skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906—Drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG10201903125QA 2008-09-23 2009-09-23 Active agent loaded uniform, rigid, spherical, nanoporous calcium phosphate particles and methods of making and using the same SG10201903125QA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9950008P 2008-09-23 2008-09-23

Publications (1)

Publication Number Publication Date
SG10201903125QA true SG10201903125QA (en) 2019-05-30

Family

ID=42074119

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201903125QA SG10201903125QA (en) 2008-09-23 2009-09-23 Active agent loaded uniform, rigid, spherical, nanoporous calcium phosphate particles and methods of making and using the same
SG10201406431QA SG10201406431QA (en) 2008-09-23 2009-09-23 Active agent loaded uniform, rigid, spherical, nanoporous calcium phosphate particles and methods of making and using the same

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201406431QA SG10201406431QA (en) 2008-09-23 2009-09-23 Active agent loaded uniform, rigid, spherical, nanoporous calcium phosphate particles and methods of making and using the same

Country Status (17)

Country Link
US (5) US8535723B2 (ja)
EP (1) EP2480210A4 (ja)
JP (1) JP5730316B2 (ja)
KR (4) KR20180089553A (ja)
CN (1) CN102802610A (ja)
AU (1) AU2009298814B2 (ja)
BR (1) BR112012006635B8 (ja)
CA (1) CA2778604C (ja)
CL (1) CL2012000726A1 (ja)
EA (1) EA027992B1 (ja)
IL (2) IL218808A (ja)
MX (1) MX356209B (ja)
MY (1) MY162982A (ja)
NZ (1) NZ599544A (ja)
SG (2) SG10201903125QA (ja)
WO (1) WO2010039560A2 (ja)
ZA (1) ZA201202948B (ja)

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CA2835771C (en) * 2009-03-18 2017-01-24 Incarda Therapeutics, Inc. Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration
EP2427178B1 (en) * 2009-05-06 2023-01-04 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
CN102470101A (zh) * 2009-08-19 2012-05-23 拜耳医药股份有限公司 用于儿科应用的药物递送系统(糯米纸囊剂)
EP2533753B1 (en) * 2009-11-10 2022-07-06 Laboratory Skin Care, Inc. Sunscreen compositions comprising uniform, rigid, spherical, nanoporous calcium phosphate particles, and methods of making and using the same
CA2861357C (en) * 2011-01-19 2022-08-23 Laboratory Skin Care, Inc. Topical minocycline compositions and methods of using the same
CN107875391A (zh) * 2011-08-16 2018-04-06 实验室护肤股份有限公司 细干颗粒腺苷组合物和包括其的局部制剂
CN102552913B (zh) * 2012-01-19 2013-06-19 中国科学院上海硅酸盐研究所 一种纳米结构磷酸钙双载药体系及其制备方法
CN103284929B (zh) * 2012-02-23 2015-08-12 黄曦 一种护肤品及其制备方法
US11844852B2 (en) * 2012-02-23 2023-12-19 Fe:I Beauty Tech, Inc. Skincare product and method of preparation thereof
CN102579355B (zh) * 2012-03-19 2013-03-06 天津大学 米托蒽醌纳米磷酸氢钙制剂及其制备方法
CZ2012724A3 (cs) * 2012-10-24 2014-07-23 Agra Group, A.S. Mezoporézní částice, jejich použití a přípravek je obsahující
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CN105336873B (zh) * 2015-11-05 2018-12-07 广州竞择微电子技术有限公司 一种柔性光电子器件用基板及其制备方法
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WO2018209107A1 (en) 2017-05-10 2018-11-15 Incarda Therapeutics, Inc. Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration
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WO2019183470A2 (en) 2018-03-22 2019-09-26 Incarda Therapeutics, Inc. A novel method to slow ventricular rate
KR102221493B1 (ko) * 2018-12-12 2021-02-26 성균관대학교산학협력단 핵산 기반의 칼슘 포스페이트 나노 소재를 합성하는 방법 및 이에 의해 합성된 핵산 기반의 칼슘 포스페이트 나노 소재
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EP2427178B1 (en) * 2009-05-06 2023-01-04 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
CN112263549A (zh) * 2013-03-15 2021-01-26 实验室护肤股份有限公司 细干颗粒类视黄醇活性剂组合物和包括其的局部制剂

Also Published As

Publication number Publication date
WO2010039560A3 (en) 2015-05-21
US20100086606A1 (en) 2010-04-08
US20190117558A1 (en) 2019-04-25
CA2778604C (en) 2021-10-05
AU2009298814B2 (en) 2016-05-05
JP2013505293A (ja) 2013-02-14
IL218808A (en) 2017-10-31
IL255112A0 (en) 2017-12-31
US10028903B2 (en) 2018-07-24
AU2009298814A1 (en) 2012-06-21
KR20160083953A (ko) 2016-07-12
EP2480210A4 (en) 2016-07-13
US20140199400A1 (en) 2014-07-17
CL2012000726A1 (es) 2013-01-11
KR101689635B1 (ko) 2016-12-26
BR112012006635B8 (pt) 2021-05-25
KR20120104188A (ko) 2012-09-20
US20240082147A1 (en) 2024-03-14
CN102802610A (zh) 2012-11-28
EA201290170A3 (ru) 2013-03-29
EA027992B1 (ru) 2017-09-29
WO2010039560A2 (en) 2010-04-08
BR112012006635B1 (pt) 2021-04-06
US20210015739A1 (en) 2021-01-21
JP5730316B2 (ja) 2015-06-10
KR20170096241A (ko) 2017-08-23
CA2778604A1 (en) 2010-04-08
MX2012003542A (es) 2012-09-07
SG10201406431QA (en) 2014-11-27
EP2480210A2 (en) 2012-08-01
IL255112B (en) 2019-09-26
US10758478B2 (en) 2020-09-01
ZA201202948B (en) 2014-08-27
US8535723B2 (en) 2013-09-17
MX356209B (es) 2018-05-18
KR20180089553A (ko) 2018-08-08
EA201290170A2 (ru) 2012-11-30
MY162982A (en) 2017-07-31
BR112012006635A2 (pt) 2016-05-03
NZ599544A (en) 2014-04-30
IL218808A0 (en) 2012-06-28

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