SG10201805706XA - Immunoglobulin-like molecules directed against fibronectin-eda - Google Patents

Immunoglobulin-like molecules directed against fibronectin-eda

Info

Publication number
SG10201805706XA
SG10201805706XA SG10201805706XA SG10201805706XA SG10201805706XA SG 10201805706X A SG10201805706X A SG 10201805706XA SG 10201805706X A SG10201805706X A SG 10201805706XA SG 10201805706X A SG10201805706X A SG 10201805706XA SG 10201805706X A SG10201805706X A SG 10201805706XA
Authority
SG
Singapore
Prior art keywords
immunoglobulin
molecules
eda
directed against
molecules directed
Prior art date
Application number
SG10201805706XA
Other languages
English (en)
Inventor
Fatih Arslan
Original Assignee
Umc Utrecht Holding Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Umc Utrecht Holding Bv filed Critical Umc Utrecht Holding Bv
Publication of SG10201805706XA publication Critical patent/SG10201805706XA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG10201805706XA 2013-12-12 2014-12-12 Immunoglobulin-like molecules directed against fibronectin-eda SG10201805706XA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL2011944 2013-12-12
NL2011943 2013-12-12

Publications (1)

Publication Number Publication Date
SG10201805706XA true SG10201805706XA (en) 2018-08-30

Family

ID=52392177

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201805706XA SG10201805706XA (en) 2013-12-12 2014-12-12 Immunoglobulin-like molecules directed against fibronectin-eda
SG11201604748YA SG11201604748YA (en) 2013-12-12 2014-12-12 Immunoglobulin-like molecules directed against fibronectin-eda

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201604748YA SG11201604748YA (en) 2013-12-12 2014-12-12 Immunoglobulin-like molecules directed against fibronectin-eda

Country Status (14)

Country Link
US (2) US10011652B2 (ko)
EP (1) EP3080163B1 (ko)
JP (1) JP6698529B2 (ko)
KR (1) KR20160108322A (ko)
CN (1) CN106170496B (ko)
AU (1) AU2014360946B2 (ko)
BR (1) BR112016013641A2 (ko)
CA (1) CA2933471A1 (ko)
IL (1) IL246187A0 (ko)
MX (1) MX2016007691A (ko)
NZ (1) NZ721984A (ko)
SG (2) SG10201805706XA (ko)
WO (1) WO2015088348A1 (ko)
ZA (1) ZA201604048B (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201805706XA (en) 2013-12-12 2018-08-30 Umc Utrecht Holding Bv Immunoglobulin-like molecules directed against fibronectin-eda
CA2970427A1 (en) * 2014-12-12 2016-06-16 Encare Biotech B.V. Immunoglobulin-like molecules directed against fibronectin-eda
GB201507908D0 (en) 2015-05-08 2015-06-24 Philogen Spa IL2 and TNF immunoconjugates
CN108276491B (zh) * 2018-02-05 2021-01-12 南京薇熙生物医药科技有限公司 一种可特异性识别hpv18 l1蛋白的单克隆抗体及其应用
WO2019212341A2 (en) 2018-05-03 2019-11-07 Encore Biotech B.V. Improved anti-fibronectin eda antibodies
CN111704653B (zh) * 2020-06-08 2023-10-03 深圳市图微安创科技开发有限公司 靶向于纤连蛋白衍生肽的抑制剂多肽化合物及其用途
DE202022100356U1 (de) 2022-01-22 2022-03-08 Fahad Ahmed Al Abbasi Ein System zur Analyse der Wirkung von Vitamin C bei stressinduzierten Herzfunktionsstörungen
WO2023170170A1 (en) 2022-03-08 2023-09-14 Fundación Para La Investigación Médica Aplicada New chimeric antigen receptor (car) cells and medical uses thereof

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980279A (en) 1986-04-15 1990-12-25 Scripps Clinic And Research Foundation Cellular fibronectin: polypeptides, anti-polypeptide antibodies and assay methods
US5843708A (en) 1988-01-05 1998-12-01 Ciba-Geigy Corporation Chimeric antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5108898A (en) * 1989-01-18 1992-04-28 Peters John H Use of fibronectin having a variable included type III repeat sequence as a marker for toxemia in pregnancy
US5420012A (en) 1989-05-08 1995-05-30 Locus Genex Oy Method for the detection of reactive conditions
WO1992017604A1 (en) 1991-03-26 1992-10-15 Otsuka Pharmaceutical Factory, Inc. Anti-eda monoclonal antibody
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
US5639641A (en) 1992-09-09 1997-06-17 Immunogen Inc. Resurfacing of rodent antibodies
US5644033A (en) 1992-12-22 1997-07-01 Health Research, Inc. Monoclonal antibodies that define a unique antigen of human B cell antigen receptor complex and methods of using same for diagnosis and treatment
EP2299275B1 (en) * 2004-07-30 2018-03-07 Adeza Biomedical Corporation Classification of the oncofetal fibronection level for pregnancy-related indications
ATE497508T1 (de) * 2004-10-01 2011-02-15 Max Planck Gesellschaft Gegen das säugetier-eag1-ionenkanalprotein gerichtete antikörper
CA2609234C (en) * 2005-06-01 2014-04-22 Micromet Ag Anti-il2 antibodies
CA2682851C (en) * 2007-04-02 2017-01-17 Philogen S.P.A. A novel antigen associated with the neovasculature of tumour metastases
WO2008130635A2 (en) * 2007-04-19 2008-10-30 The Texas A&M University System Formation of superfibronectin by bbk32 and uses therefor
ES2398536T3 (es) * 2007-07-25 2013-03-20 Philogen S.P.A. El antígeno ED-A de fibronectina está asociado con la neovasculatura de la metástasis tumoral
US20130274448A1 (en) 2010-10-26 2013-10-17 Umc Utrecht Holding B.V. Method for preventing myocardial infarction-related complications
US20130224236A1 (en) * 2010-11-03 2013-08-29 University Of Washington Hsv-1 epitopes and methods for using same
SG10201805706XA (en) 2013-12-12 2018-08-30 Umc Utrecht Holding Bv Immunoglobulin-like molecules directed against fibronectin-eda
CA2970427A1 (en) 2014-12-12 2016-06-16 Encare Biotech B.V. Immunoglobulin-like molecules directed against fibronectin-eda

Also Published As

Publication number Publication date
CN106170496B (zh) 2019-10-08
JP6698529B2 (ja) 2020-05-27
KR20160108322A (ko) 2016-09-19
US20180346557A1 (en) 2018-12-06
WO2015088348A1 (en) 2015-06-18
NZ721984A (en) 2020-01-31
CN106170496A (zh) 2016-11-30
US20160368974A1 (en) 2016-12-22
SG11201604748YA (en) 2016-07-28
US10011652B2 (en) 2018-07-03
ZA201604048B (en) 2018-05-30
JP2017506061A (ja) 2017-03-02
EP3080163B1 (en) 2020-02-12
BR112016013641A2 (pt) 2017-08-08
EP3080163A1 (en) 2016-10-19
IL246187A0 (en) 2016-07-31
US10723789B2 (en) 2020-07-28
MX2016007691A (es) 2017-05-01
AU2014360946A1 (en) 2016-07-14
CA2933471A1 (en) 2015-06-18
AU2014360946B2 (en) 2020-06-25

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