SG10201803601SA - Methods and systems for processing a cell culture - Google Patents

Methods and systems for processing a cell culture

Info

Publication number
SG10201803601SA
SG10201803601SA SG10201803601SA SG10201803601SA SG10201803601SA SG 10201803601S A SG10201803601S A SG 10201803601SA SG 10201803601S A SG10201803601S A SG 10201803601SA SG 10201803601S A SG10201803601S A SG 10201803601SA SG 10201803601S A SG10201803601S A SG 10201803601SA
Authority
SG
Singapore
Prior art keywords
systems
methods
processing
cell culture
filtration
Prior art date
Application number
SG10201803601SA
Other languages
English (en)
Inventor
Hang Zhou
Benjamin Wright
Marcella Yu
Jin Yin
Konstantin Konstantinov
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51660627&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201803601S(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of SG10201803601SA publication Critical patent/SG10201803601SA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04Filters; Permeable or porous membranes or plates, e.g. dialysis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10Perfusion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18External loop; Means for reintroduction of fermented biomass or liquid percolate
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/14Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus with filters, sieves or membranes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10Separation or concentration of fermentation products
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/12Purification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Water Supply & Treatment (AREA)
  • Immunology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
SG10201803601SA 2013-09-16 2014-09-16 Methods and systems for processing a cell culture SG10201803601SA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361878502P 2013-09-16 2013-09-16

Publications (1)

Publication Number Publication Date
SG10201803601SA true SG10201803601SA (en) 2018-06-28

Family

ID=51660627

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201803601SA SG10201803601SA (en) 2013-09-16 2014-09-16 Methods and systems for processing a cell culture
SG11201601899TA SG11201601899TA (en) 2013-09-16 2014-09-16 Methods and systems for processing a cell culture

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201601899TA SG11201601899TA (en) 2013-09-16 2014-09-16 Methods and systems for processing a cell culture

Country Status (18)

Country Link
US (2) US20150158907A1 (de)
EP (1) EP3047013B1 (de)
JP (4) JP6925127B2 (de)
KR (3) KR102369211B1 (de)
CN (2) CN113444620B (de)
AU (3) AU2014318420B2 (de)
BR (2) BR122021001466B1 (de)
CA (1) CA2924332C (de)
CY (1) CY1124684T1 (de)
DK (1) DK3047013T3 (de)
EA (2) EA031652B1 (de)
ES (1) ES2891728T3 (de)
HK (1) HK1222672A1 (de)
HU (1) HUE055888T2 (de)
IL (1) IL244552B (de)
MX (2) MX2016003440A (de)
SG (2) SG10201803601SA (de)
WO (1) WO2015039115A1 (de)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10421949B2 (en) 2013-02-22 2019-09-24 Genzyme Corporation Microcarrier perfusion culturing methods and uses thereof
CA2901950A1 (en) 2013-02-22 2014-08-28 Genzyme Corporation Microcarrier perfusion culturing methods and uses thereof
IL285529B2 (en) * 2014-05-13 2023-03-01 Amgen Inc Process control systems and methods for the use of filters and filtration processes
TWI743024B (zh) 2014-06-06 2021-10-21 美商健臻公司 灌注培養方法及其用途
TWI776235B (zh) 2014-06-09 2022-09-01 美商健臻公司 種子罐培養法(seed train processes)及其用途
RU2713126C2 (ru) * 2014-10-24 2020-02-03 Джензим Корпорейшн Способ предотвращения контаминации системы
RU2712746C2 (ru) 2014-12-22 2020-01-30 Джензим Корпорейшн Способы культивирования клетки млекопитающего
JP6457338B2 (ja) * 2015-05-28 2019-01-23 株式会社日立製作所 液体還流容器、細胞濃縮装置及び細胞濃縮システム
WO2017117218A1 (en) 2015-12-30 2017-07-06 Momenta Pharmaceuticals, Inc. Methods related to biologics
ITUB20160272A1 (it) * 2016-01-22 2017-07-22 Univ Degli Studi Di Palermo Bioreattore a perfusione autosufficiente monouso per crescite cellulari 3D
US20200289987A1 (en) * 2016-03-14 2020-09-17 Pendotech Processing System for Multiple Tangential Flow Filtration Stations in Bioprocessing Applications
CN109072154A (zh) * 2016-04-15 2018-12-21 勃林格殷格翰国际公司 细胞保留装置和方法
US11473047B2 (en) 2016-07-19 2022-10-18 The Automation Partnership (Cambridge) Limited Liquid filtration and pump system
US11560539B2 (en) 2016-07-19 2023-01-24 The Automation Partnership (Cambridge) Limited Reversible liquid filtration system
CN106047707B (zh) * 2016-08-03 2018-11-13 广州赛泊泰生物技术有限公司 贴壁/悬浮型细胞培养单元、装置、系统及方法
TWI675696B (zh) 2017-06-01 2019-11-01 美商Emd密理博公司 用於灌注應用之切向流過濾裝置
DK3697887T3 (da) 2017-10-16 2022-05-02 Regeneron Pharma Perfusionsfremgangsmåder
JP7237964B2 (ja) * 2017-11-22 2023-03-13 コーニング インコーポレイテッド 灌流バイオリアクターシステムおよび灌流細胞培養方法
US11920119B2 (en) 2018-02-09 2024-03-05 Global Life Sciences Solutions Usa Llc Systems and methods for bioprocessing
US11932842B2 (en) 2018-02-09 2024-03-19 Global Life Sciences Solutions Usa Llc Bioprocessing apparatus
US11371007B2 (en) * 2018-02-09 2022-06-28 Global Life Sciences Solutions Usa Llc System and method for fluid flow management in a bioprocessing system
EP3749749A1 (de) * 2018-02-09 2020-12-16 Global Life Sciences Solutions USA LLC Bioverarbeitungsvorrichtung
US11414639B2 (en) 2018-02-09 2022-08-16 Global Life Sciences Solutions Usa Llc Bioprocessing vessel
CN110241012B (zh) * 2018-03-09 2022-11-01 嘉和生物药业有限公司 一种生物大分子上游分阶段截留的生产方法、生产模块及在生产中的应用
US20190338238A1 (en) * 2018-05-04 2019-11-07 Genzyme Corporation Perfusion Bioreactor With Filtration Systems
US20210214702A1 (en) * 2018-06-01 2021-07-15 Gennova Biopharmaceuticals Limited Process for production of recombinant tnk-tpa by packed-bed perfusion system
EP3843884A1 (de) * 2018-08-29 2021-07-07 Cytiva Sweden AB System zur filtrierung und zugehöriges verfahren
AU2019336148A1 (en) * 2018-09-06 2021-04-29 Momenta Pharmaceuticals, Inc. Methods of continuous cell culture
KR20210060473A (ko) * 2018-09-21 2021-05-26 씨티바 스웨덴 에이비 관류 바이오프로세싱 시스템 및 이를 작동시키는 방법
US20220364034A1 (en) * 2018-11-02 2022-11-17 WuXi Biologics Ireland Limited Cell culture process by intensified perfusion with continuous harvest and without cell bleeding
US10647954B1 (en) 2018-11-15 2020-05-12 Flaskworks, Llc Dendritic cell generating apparatus and method
AU2020253327A1 (en) * 2019-04-01 2021-09-23 Boehringer Ingelheim International Gmbh Integrated and continuous recombinant protein manufacturing
CN114072217A (zh) * 2019-06-28 2022-02-18 信达生物制药(苏州)有限公司 组合式层析装置、无缝连接层析方法和生物制剂的纯化方法
US11566217B2 (en) 2019-08-13 2023-01-31 Flaskworks, Llc Duty cycle for cell culture systems
EP4048293A4 (de) 2019-10-21 2023-12-06 Flaskworks, LLC Systeme und verfahren zur zellzüchtung
EP3878542A1 (de) * 2020-03-11 2021-09-15 Bayer AG Filtermembranen als antischaumniveausicherungen
KR102230957B1 (ko) * 2020-05-18 2021-03-23 경북대학교 산학협력단 Ev 여과장치
US20220119759A1 (en) * 2020-10-19 2022-04-21 Emd Millipore Corporation Cascade Tangential Flow Filtration Systems for Perfusion of Cell Culture
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
CN112831416A (zh) * 2021-01-29 2021-05-25 上海睿钰生物科技有限公司 一种体外生命维持灌流培养系统及其控制方法
EP4313356A2 (de) 2021-04-16 2024-02-07 Repligen Corporation Filtrationssystem und -verfahren
CN217868904U (zh) * 2021-04-29 2022-11-22 尤尼沃尔塞尔斯技术股份公司 用于生产和纯化目标生物制剂和用于生产胞外体的系统
EP4370647A1 (de) 2021-07-15 2024-05-22 Just-Evotec Biologics, Inc. Bidirektionales perfusionssystem mit tangentialer strömungsfiltration (tff)
US20230131609A1 (en) * 2021-10-21 2023-04-27 Alit Biotech (Shanghai) Co., Ltd. Biological filtration systems and controlling methods thereof
EP4268943A1 (de) 2022-04-27 2023-11-01 Levitronix GmbH Vorrichtung zur tangentialflussfiltration eines fluids
WO2024092004A1 (en) * 2022-10-26 2024-05-02 National Resilience, Inc. Bioreactor systems and methods of operating same

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60804A (ja) * 1983-06-20 1985-01-05 Poritetsukusu:Kk ウルトラフイルタ装置
JPS6188872A (ja) * 1984-10-09 1986-05-07 Snow Brand Milk Prod Co Ltd 高濃度連続培養方法及び装置
US4885087A (en) * 1986-11-26 1989-12-05 Kopf Henry B Apparatus for mass transfer involving biological/pharmaceutical media
US6022742A (en) * 1986-11-26 2000-02-08 Kopf; Henry B. Culture device and method
US5030346A (en) * 1988-01-15 1991-07-09 Henry Filters, Inc. Pump for filtration system
US5401650A (en) * 1990-10-24 1995-03-28 The Mount Sinai School Of Medicine Of The City University Of New York Cloning and expression of biologically active α-galactosidase A
JPH0531335A (ja) * 1991-07-30 1993-02-09 Toto Ltd 分離膜洗浄方法
US6544424B1 (en) 1999-12-03 2003-04-08 Refined Technology Company Fluid filtration system
US7695627B2 (en) * 2002-06-19 2010-04-13 Northwest Biotherapeutics, Inc. Tangential flow filtration devices and methods for leukocyte enrichment
US7875448B2 (en) 2004-01-12 2011-01-25 Single Use Brx, Llc Bioreactor systems and disposable bioreactor
DK1720972T3 (da) * 2004-03-05 2014-04-14 Dsm Ip Assets Bv Fremgangsmåde til celledyrkning ved hjælp af fortløbende perfusion og vekslende tangentialt flow
EP1963367A4 (de) * 2005-12-06 2009-05-13 Amgen Inc Reinigungsschritte in mehrstufigen proteinreinigungsverfahren
GB0606144D0 (en) * 2006-03-28 2006-05-10 Ge Healthcare Bio Sciences Ab Automated crossflow filtration method and system
BRPI0714347A2 (pt) * 2006-07-14 2013-05-07 Dsm Ip Assets Bv processo aperfeiÇoado para o cultivo de cÉlulas
FR2925923B1 (fr) * 2007-12-28 2009-12-18 Michelin Soc Tech Procede et dispositif de fabrication d'un cable a deux couches du type gomme in situ
JP5003614B2 (ja) * 2008-07-03 2012-08-15 株式会社日立プラントテクノロジー 生体細胞の分離方法及び培養装置
US9446354B2 (en) * 2010-08-25 2016-09-20 Repligen Corporation Device, system and process for modification or concentration of cell-depleted fluid
CN103415610B (zh) * 2011-03-18 2016-10-19 通用电气健康护理生物科学股份公司 用于培养细胞的弹性袋
WO2013109520A1 (en) * 2012-01-18 2013-07-25 Bayer Healthcare Llc Perfusion bioreactor systems and methods of operating the same
BR112014020120B1 (pt) * 2012-02-20 2020-09-15 Bayer Aktiengesellschaft Separador de sólidos de canais inclinados para reter e recircular sólidos de uma mistura de um reator e unidade biorreatora
US9663753B2 (en) 2012-09-27 2017-05-30 Ge Healthcare Bio-Sciences Ab Tangential flow perfusion system

Also Published As

Publication number Publication date
MX2016003440A (es) 2016-11-11
CN105722967B (zh) 2021-03-19
AU2014318420B2 (en) 2020-01-16
CN105722967A (zh) 2016-06-29
AU2020202568A1 (en) 2020-05-07
EP3047013A1 (de) 2016-07-27
IL244552A0 (en) 2016-04-21
EA035665B1 (ru) 2020-07-23
JP2022050549A (ja) 2022-03-30
EA201892084A1 (ru) 2019-02-28
WO2015039115A1 (en) 2015-03-19
AU2014318420A1 (en) 2016-04-14
EA201690602A1 (ru) 2016-07-29
EA031652B1 (ru) 2019-02-28
HUE055888T2 (hu) 2022-01-28
DK3047013T3 (da) 2021-11-15
CN113444620A (zh) 2021-09-28
KR20230142653A (ko) 2023-10-11
CN113444620B (zh) 2024-03-29
CY1124684T1 (el) 2022-07-22
KR102369211B1 (ko) 2022-03-03
JP7008746B2 (ja) 2022-01-25
US20210269477A1 (en) 2021-09-02
IL244552B (en) 2020-04-30
SG11201601899TA (en) 2016-04-28
JP2016530893A (ja) 2016-10-06
EP3047013B1 (de) 2021-08-18
JP2023058588A (ja) 2023-04-25
CA2924332C (en) 2023-03-14
KR20220031937A (ko) 2022-03-14
BR112016005545B1 (pt) 2021-06-01
ES2891728T3 (es) 2022-01-31
JP7227406B2 (ja) 2023-02-21
KR20160055866A (ko) 2016-05-18
US20150158907A1 (en) 2015-06-11
JP2020124204A (ja) 2020-08-20
MX2021007792A (es) 2021-08-11
HK1222672A1 (zh) 2017-07-07
AU2020202568B2 (en) 2022-06-02
BR122021001466B1 (pt) 2021-10-13
JP6925127B2 (ja) 2021-08-25
CA2924332A1 (en) 2015-03-19
AU2022221495A1 (en) 2022-09-22

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