SG10201604676WA - Therapy for subarachnoid hemorrhage and ischemia - Google Patents

Therapy for subarachnoid hemorrhage and ischemia

Info

Publication number
SG10201604676WA
SG10201604676WA SG10201604676WA SG10201604676WA SG10201604676WA SG 10201604676W A SG10201604676W A SG 10201604676WA SG 10201604676W A SG10201604676W A SG 10201604676WA SG 10201604676W A SG10201604676W A SG 10201604676WA SG 10201604676W A SG10201604676W A SG 10201604676WA
Authority
SG
Singapore
Prior art keywords
ischemia
therapy
subarachnoid hemorrhage
subarachnoid
hemorrhage
Prior art date
Application number
SG10201604676WA
Other languages
English (en)
Inventor
Michael Tymianski
Original Assignee
Nono Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA2762338A external-priority patent/CA2762338C/en
Application filed by Nono Inc filed Critical Nono Inc
Publication of SG10201604676WA publication Critical patent/SG10201604676WA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG10201604676WA 2011-12-13 2012-12-13 Therapy for subarachnoid hemorrhage and ischemia SG10201604676WA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161570264P 2011-12-13 2011-12-13
CA2762338A CA2762338C (en) 2011-12-13 2011-12-15 Therapy for subarachnoid hemorrhage and ischemia
US201261617001P 2012-03-28 2012-03-28

Publications (1)

Publication Number Publication Date
SG10201604676WA true SG10201604676WA (en) 2016-07-28

Family

ID=51228598

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201604676WA SG10201604676WA (en) 2011-12-13 2012-12-13 Therapy for subarachnoid hemorrhage and ischemia
SG11201403239UA SG11201403239UA (en) 2011-12-13 2012-12-13 Therapy for subarachnoid hemorrhage and ischemia

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201403239UA SG11201403239UA (en) 2011-12-13 2012-12-13 Therapy for subarachnoid hemorrhage and ischemia

Country Status (12)

Country Link
EP (1) EP2800575B1 (cg-RX-API-DMAC7.html)
JP (3) JP6279483B2 (cg-RX-API-DMAC7.html)
KR (2) KR20200057802A (cg-RX-API-DMAC7.html)
CN (1) CN104053448B (cg-RX-API-DMAC7.html)
AU (1) AU2012354072B2 (cg-RX-API-DMAC7.html)
DK (1) DK2800575T3 (cg-RX-API-DMAC7.html)
ES (1) ES2731266T3 (cg-RX-API-DMAC7.html)
IL (1) IL233103B (cg-RX-API-DMAC7.html)
MX (1) MX364562B (cg-RX-API-DMAC7.html)
SG (2) SG10201604676WA (cg-RX-API-DMAC7.html)
WO (1) WO2013088382A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201404636B (cg-RX-API-DMAC7.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2765169C (en) 2009-06-10 2019-06-18 Nono Inc. Model systems and treatment regimes for treatment of neurological disease
HRP20220519T1 (hr) 2011-06-24 2022-05-27 Nono Inc. Kombinacijska terapija ishemije
US9241970B2 (en) 2011-12-13 2016-01-26 Nono Inc. Therapy for subarachnoid hemorrhage and ischemia
PL3074032T3 (pl) * 2013-12-01 2019-06-28 University Of Copenhagen Pochodne kwasów tłuszczowych dimerycznych inhibitorów psd-95
UA123820C2 (uk) 2014-05-28 2021-06-09 Ноно Інк. Хлоридна сіль пептиду tat-nr2b9c
CN107312071B (zh) * 2016-04-27 2018-11-06 拜西欧斯(北京)生物技术有限公司 兴奋性神经毒性相关损伤的治疗方法
US20190134150A1 (en) * 2016-04-27 2019-05-09 Biocells (Beijing) Biotech Co., Ltd. Therapeutic methods for excitatory neurotoxicity-related injuries
CN109985047B (zh) * 2017-12-29 2021-07-27 广州市赛普特医药科技股份有限公司 5α-雄甾-3β,5,6β-三醇在制备治疗出血性脑卒中药物中的应用
CN109009111A (zh) * 2018-07-16 2018-12-18 重庆大学 低场核磁共振脑出血动态监护仪控制系统
CN113284126B (zh) * 2021-06-10 2022-06-24 安徽省立医院(中国科学技术大学附属第一医院) 人工神经网络图像分析预测脑积水分流手术疗效的方法
CN113735938B (zh) * 2021-07-30 2024-11-08 英纳氏(珠海)药业有限公司 一种神经保护多肽化合物及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7510824B2 (en) 1999-06-02 2009-03-31 Nono Inc. Method of screening peptides useful in treating traumatic injury to the brain or spinal cord
EP1884521A1 (en) * 2006-07-31 2008-02-06 Xigen S.A. Fusion peptide for inhibiting interaction of neuronal NMDA receptor (NMDAR) and NMDAR interacting proteins
ES2446292T3 (es) * 2007-03-02 2014-03-07 Nono Inc. Tratamiento del accidente cerebrovascular y otras enfermedades sin inhibir los canales de calcio de tipo N
CA2765169C (en) * 2009-06-10 2019-06-18 Nono Inc. Model systems and treatment regimes for treatment of neurological disease

Also Published As

Publication number Publication date
JP2020128419A (ja) 2020-08-27
CN104053448B (zh) 2017-04-05
JP6279483B2 (ja) 2018-02-14
JP6741642B2 (ja) 2020-08-19
JP2015501834A (ja) 2015-01-19
AU2012354072B2 (en) 2017-04-27
JP2018052962A (ja) 2018-04-05
IL233103A0 (en) 2014-07-31
AU2012354072A1 (en) 2014-07-03
ES2731266T3 (es) 2019-11-14
DK2800575T3 (da) 2019-07-01
KR20200057802A (ko) 2020-05-26
WO2013088382A1 (en) 2013-06-20
MX364562B (es) 2019-04-30
KR102114490B1 (ko) 2020-05-25
MX2014007031A (es) 2015-02-20
SG11201403239UA (en) 2014-09-26
EP2800575A4 (en) 2015-09-23
CN104053448A (zh) 2014-09-17
ZA201404636B (en) 2015-10-28
KR20140108266A (ko) 2014-09-05
EP2800575A1 (en) 2014-11-12
EP2800575B1 (en) 2019-05-22
IL233103B (en) 2021-03-25

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