SG10201405455UA - Cells and methods for obtaining them - Google Patents

Cells and methods for obtaining them

Info

Publication number
SG10201405455UA
SG10201405455UA SG10201405455UA SG10201405455UA SG10201405455UA SG 10201405455U A SG10201405455U A SG 10201405455UA SG 10201405455U A SG10201405455U A SG 10201405455UA SG 10201405455U A SG10201405455U A SG 10201405455UA SG 10201405455U A SG10201405455U A SG 10201405455UA
Authority
SG
Singapore
Prior art keywords
cells
obtaining
methods
Prior art date
Application number
SG10201405455UA
Other languages
English (en)
Inventor
Pentao Liu
Wei Wang
Jiang Yang
Original Assignee
Genome Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genome Res Ltd filed Critical Genome Res Ltd
Publication of SG10201405455UA publication Critical patent/SG10201405455UA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/235—Leukemia inhibitory factor [LIF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/602—Sox-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/603—Oct-3/4
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/604—Klf-4
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/606—Transcription factors c-Myc
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/727—Kinases (EC 2.7.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Transplantation (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG10201405455UA 2009-09-07 2010-09-07 Cells and methods for obtaining them SG10201405455UA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24028209P 2009-09-07 2009-09-07
GBGB0915523.5A GB0915523D0 (en) 2009-09-07 2009-09-07 Cells and methods for obtaining them
US27620309P 2009-09-08 2009-09-08

Publications (1)

Publication Number Publication Date
SG10201405455UA true SG10201405455UA (en) 2014-10-30

Family

ID=41203246

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201405455UA SG10201405455UA (en) 2009-09-07 2010-09-07 Cells and methods for obtaining them
SG2012015343A SG178613A1 (en) 2009-09-07 2010-09-07 Cells and methods for obtaining them

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG2012015343A SG178613A1 (en) 2009-09-07 2010-09-07 Cells and methods for obtaining them

Country Status (8)

Country Link
US (1) US9512407B2 (enExample)
EP (1) EP2475774A1 (enExample)
JP (1) JP5944315B2 (enExample)
CN (1) CN102822345B (enExample)
CA (1) CA2773291A1 (enExample)
GB (1) GB0915523D0 (enExample)
SG (2) SG10201405455UA (enExample)
WO (1) WO2011027180A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9422525B2 (en) 2009-09-30 2016-08-23 Agency For Science, Technology And Research Nuclear receptor and mutant thereof and the use of the same in the reprogramming of cells
JP5921558B2 (ja) * 2010-10-14 2016-05-24 ユニバーシティ オブ セントラル フロリダ リサーチ ファウンデーション，インコーポレイテッド 心臓人工多能性幹細胞ならびに心筋の修復および再生に使用する方法
GB2496375A (en) 2011-10-28 2013-05-15 Kymab Ltd A non-human assay vertebrate comprising human antibody loci and human epitope knock-in, and uses thereof
GB201122047D0 (en) 2011-12-21 2012-02-01 Kymab Ltd Transgenic animals
CA2924735C (en) * 2013-09-20 2023-02-28 Lonza Ltd Methods for nuclear reprogramming of cells
US10023879B2 (en) * 2014-06-04 2018-07-17 Fate Therapeutics, Inc. Minimal volume reprogramming of mononuclear cells
EP3384007B1 (en) 2015-11-30 2024-03-27 Beihao Stem Cell and Regenerative Medicine Research Institute Co., Ltd. Improved methods for reprograming non-pluripotent cells into pluripotent stem cells
CN109750000A (zh) * 2017-11-06 2019-05-14 内蒙古赛科星家畜种业与繁育生物技术研究院有限公司 利用XistTale抑制性转录因子R6制备新型动物细胞系R6-MEFs方法及用途
CN109913494A (zh) * 2019-02-12 2019-06-21 北京呈诺医学科技有限公司 一种新的ips细胞的诱导方法
CN110218741B (zh) * 2019-05-31 2020-12-25 华中农业大学 采用串联sgRNA同步激活多个猪内源性干细胞因子转录活性的方法
CN110592014A (zh) * 2019-08-14 2019-12-20 广东美赛尔细胞生物科技有限公司 一种在nk细胞治疗中免辐照体外体内持续去除饲养细胞的方法
CN114703227B (zh) * 2022-01-27 2023-11-10 中国科学院生态环境研究中心 基于MCF-7细胞系构建的RARα效应物体外筛选方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03130081A (ja) 1989-06-30 1991-06-03 Inst Natl Sante & Rech Med <Inserm> ヒトおよびマウスレチノイン酸レセプターおよびそれをコードする遺伝子
US5663303A (en) 1991-11-04 1997-09-02 Institut National De La Sante Et De La Recherche Medicale Antibodies specific for retinoic acid receptor-γ
KR20030017502A (ko) 2000-04-28 2003-03-03 에프. 호프만-라 로슈 아게 파라(설포닐)아릴 및 헤테로아릴
US20070224615A1 (en) * 2003-07-09 2007-09-27 Invitrogen Corporation Methods for assaying protein-protein interactions
US7476673B2 (en) 2003-12-30 2009-01-13 Allergan, Inc. Disubstituted chalcone oximes as selective agonists of RARγ retinoid receptors
WO2005080973A1 (en) 2004-02-13 2005-09-01 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with human nuclear receptor nr5a1 (nr5a1)
WO2005082344A1 (en) 2004-02-24 2005-09-09 Smithkline Beecham Corporation Lhr1 activators as medicaments
JP4395193B2 (ja) 2005-08-01 2010-01-06 ニューポテンシャル，インコーポレイテッド 回復能を有する再プログラムされた細胞の作製
ZA200804673B (en) * 2005-12-13 2009-11-25 Univ Kyoto Nuclear reprogramming factor
WO2008064136A2 (en) 2006-11-17 2008-05-29 Acadia Pharmaceuticals Inc. Compounds with activity at retinoic acid receptors
ATE554775T1 (de) 2007-11-16 2012-05-15 Baylor College Medicine Phospholipid-zusammensetzungen und ihre verwendungen
US9683232B2 (en) 2007-12-10 2017-06-20 Kyoto University Efficient method for nuclear reprogramming
KR101532442B1 (ko) 2007-12-10 2015-06-29 고쿠리츠 다이가쿠 호진 교토 다이가쿠 효율적인 핵 초기화 방법
CN101250502A (zh) * 2008-04-01 2008-08-27 中国科学院上海生命科学研究院 一种诱导的多潜能干细胞的制备方法
US9422525B2 (en) * 2009-09-30 2016-08-23 Agency For Science, Technology And Research Nuclear receptor and mutant thereof and the use of the same in the reprogramming of cells

Also Published As

Publication number Publication date
SG178613A1 (en) 2012-04-27
GB0915523D0 (en) 2009-10-07
US9512407B2 (en) 2016-12-06
CN102822345A (zh) 2012-12-12
US20120315703A1 (en) 2012-12-13
CA2773291A1 (en) 2011-03-10
JP2013503622A (ja) 2013-02-04
WO2011027180A1 (en) 2011-03-10
EP2475774A1 (en) 2012-07-18
JP5944315B2 (ja) 2016-07-05
CN102822345B (zh) 2016-06-08

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