SE9903930D0 - Novel compounds and a novel process for their preparation - Google Patents
Novel compounds and a novel process for their preparationInfo
- Publication number
- SE9903930D0 SE9903930D0 SE9903930A SE9903930A SE9903930D0 SE 9903930 D0 SE9903930 D0 SE 9903930D0 SE 9903930 A SE9903930 A SE 9903930A SE 9903930 A SE9903930 A SE 9903930A SE 9903930 D0 SE9903930 D0 SE 9903930D0
- Authority
- SE
- Sweden
- Prior art keywords
- novel
- preparation
- compounds
- novel compounds
- oxabenzonorbornadienes
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- XYFCBTPGUUZFHI-UHFFFAOYSA-N Phosphine Chemical compound P XYFCBTPGUUZFHI-UHFFFAOYSA-N 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 1
- ZKPRFGFRFQXTIU-UHFFFAOYSA-N ctk1a3528 Chemical class C1=CC=CC2=C(O3)C=CC3=C21 ZKPRFGFRFQXTIU-UHFFFAOYSA-N 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 239000012038 nucleophile Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229910000073 phosphorus hydride Inorganic materials 0.000 abstract 1
- 229910052703 rhodium Inorganic materials 0.000 abstract 1
- 239000010948 rhodium Substances 0.000 abstract 1
- MHOVAHRLVXNVSD-UHFFFAOYSA-N rhodium atom Chemical compound [Rh] MHOVAHRLVXNVSD-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
- C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
- C07C205/38—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to a carbon atom of a six-membered aromatic ring, e.g. nitrodiphenyl ethers
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/44—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton bound to carbon atoms of the same ring or condensed ring system
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/52—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/24—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/20—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/18—Ethers having an ether-oxygen atom bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C43/196—Ethers having an ether-oxygen atom bound to a carbon atom of a ring other than a six-membered aromatic ring containing hydroxy or O-metal groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/235—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring and to a carbon atom of a ring other than a six-membered aromatic ring
- C07C43/253—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring and to a carbon atom of a ring other than a six-membered aromatic ring containing hydroxy or O-metal groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/24—Preparation of carboxylic acid esters by reacting carboxylic acids or derivatives thereof with a carbon-to-oxygen ether bond, e.g. acetal, tetrahydrofuran
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/013—Esters of alcohols having the esterified hydroxy group bound to a carbon atom of a ring other than a six-membered aromatic ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
- C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
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- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
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- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Catalysts (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Quinoline Compounds (AREA)
Priority Applications (26)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9903930A SE9903930D0 (sv) | 1999-10-29 | 1999-10-29 | Novel compounds and a novel process for their preparation |
CNB008177481A CN1231439C (zh) | 1999-10-29 | 2000-10-26 | 在膦配体存在下经铑催化的开环反应制备的新的氢化萘化合物 |
CA002387675A CA2387675C (en) | 1999-10-29 | 2000-10-26 | Novel hydronaphtalene compounds, prepared by a rhodium catalyzed ring opening reaction in the presence of phosphine ligand |
PCT/SE2000/002090 WO2001030734A1 (en) | 1999-10-29 | 2000-10-26 | Novel hydronaphtalene compounds, prepared by a rhodium catalyzed ring opening reaction in the presence of phosphine ligand |
AT00975109T ATE275120T1 (de) | 1999-10-29 | 2000-10-26 | Neue hydronaphthalene, hergestellt durch eine rhodium-katalysierte ringöffnungsreaktion in anwesenheit eines phosphinliganden |
SI200030491T SI1228024T1 (en) | 1999-10-29 | 2000-10-26 | Novel hydronaphthalene compounds, prepared by a rhodium catalyzed ring opening reaction in the presence of phosphine ligand |
MXPA02004224A MXPA02004224A (es) | 1999-10-29 | 2000-10-26 | Nuevos compuestos de hidronaftaleno preparados mediante una reaccion de apertura de anillo catalizada por rodio, en presencia de ligando de fosfina. |
NZ518451A NZ518451A (en) | 1999-10-29 | 2000-10-26 | A hydronaphtalene ring compound, prepared by a rhodium catalyzed ring opening reaction in the presence of phosphine ligand |
DE60013471T DE60013471T2 (de) | 1999-10-29 | 2000-10-26 | Neue hydronaphthalene, hergestellt durch eine rhodium-katalysierte ringöffnungsreaktion in anwesenheit eines phosphinliganden |
KR1020027005436A KR100741177B1 (ko) | 1999-10-29 | 2000-10-26 | 포스핀 리간드의 존재하에서 로듐 촉매 고리 열림 반응에의해 제조하는, 신규 히드로나프탈렌 화합물 |
PT00975109T PT1228024E (pt) | 1999-10-29 | 2000-10-26 | Novos compostos de hidronaftaleno, preprados por uma reaccao de abertura de anelcatalisada pelo rodio na presenca de um ligando de fosfina |
AU13206/01A AU776118B2 (en) | 1999-10-29 | 2000-10-26 | Novel hydronaphtalene compounds, prepared by a rhodium catalyzed ring opening reaction in the presence of phosphine ligand |
BR0015117-3A BR0015117A (pt) | 1999-10-29 | 2000-10-26 | Composto, composição farmacêutica, métodos para tratar um paciente quanto a dor, quanto a doença de parkinson, quanto ao câncer, quanto a aids, processos para preparar um composto, para preparar (1s, 2s) -n- (1-hidróxi-1,2-diidro-naftalen-2-il)- benzeno sulfonamida, e para preparar o éster dimetìlico do áciso (1s*,2r*) -2- (hidróxi -1,2- diidro - naftalen -2- il ) malÈnico |
ES00975109T ES2225253T3 (es) | 1999-10-29 | 2000-10-26 | Nuevos compuestos hidronaftalenicos preparados mediante una reaccion de apertura del anillo catalizada por rodio en presencia de un ligando de fosfina. |
EP00975109A EP1228024B1 (de) | 1999-10-29 | 2000-10-26 | Neue hydronaphthalene, hergestellt durch eine rhodium-katalysierte ringöffnungsreaktion in anwesenheit eines phosphinliganden |
JP2001533091A JP2003512446A (ja) | 1999-10-29 | 2000-10-26 | ホスフィン配位子の存在下のロジウム触媒作用開環反応により製造された新規なヒドロナフタレン化合物 |
EP04015462A EP1498406A1 (de) | 1999-10-29 | 2000-10-26 | Neue Hydronaphthalene, hergestellt durch eine rhodium-katalysierte Ringöffnungsreaktion in Anwesenheit eines Phosphinliganden |
US09/763,759 US6525068B1 (en) | 1999-10-29 | 2000-10-26 | Hydronaphtalene compounds, prepared by a rhodium catalyzed ring opening reaction in the presence of phosphine ligand |
IL14936800A IL149368A0 (en) | 1999-10-29 | 2000-10-26 | Novel hydronaphthalene compounds, prepared by a rhodium catalyzed ring opening reaction in the presence of phosphine ligand |
ZA200203050A ZA200203050B (en) | 1999-10-29 | 2002-04-17 | Novel hydronaphtalene compounds, prepared by a rhodium catalyzed ring opening reaction in the presence of phosphine ligand. |
IL149368A IL149368A (en) | 1999-10-29 | 2002-04-25 | Hydronaphthalene compounds, pharmaceutical compositions comprising them, use thereof, and their preparation by a rhodium catalyzed ring opening reaction in the presence of phosphine ligand |
NO20021968A NO328015B1 (no) | 1999-10-29 | 2002-04-25 | Nye hydronaftalenforbindelsen fremstilt ved rhodiumkatalysert ringapningsreaksjon i naervaer av fosfinligand, samt preparater som innbefatter slike forbindelser |
HK02108588.9A HK1047083B (zh) | 1999-10-29 | 2002-11-28 | 在膦配體存在下經銠催化的開環反應製備的新的氫化萘化合物 |
US10/317,183 US6784210B2 (en) | 1999-10-29 | 2002-12-12 | Compound and a novel process for their preparation |
US10/855,783 US7420003B2 (en) | 1999-10-29 | 2004-05-28 | Compounds and a novel process for their preparation |
US12/219,752 US20080300271A1 (en) | 1999-10-29 | 2008-07-28 | Novel compounds and a novel process for their preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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SE9903930A SE9903930D0 (sv) | 1999-10-29 | 1999-10-29 | Novel compounds and a novel process for their preparation |
Publications (1)
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SE9903930D0 true SE9903930D0 (sv) | 1999-10-29 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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SE9903930A SE9903930D0 (sv) | 1999-10-29 | 1999-10-29 | Novel compounds and a novel process for their preparation |
Country Status (20)
Country | Link |
---|---|
US (4) | US6525068B1 (de) |
EP (2) | EP1228024B1 (de) |
JP (1) | JP2003512446A (de) |
KR (1) | KR100741177B1 (de) |
CN (1) | CN1231439C (de) |
AT (1) | ATE275120T1 (de) |
AU (1) | AU776118B2 (de) |
BR (1) | BR0015117A (de) |
CA (1) | CA2387675C (de) |
DE (1) | DE60013471T2 (de) |
ES (1) | ES2225253T3 (de) |
HK (1) | HK1047083B (de) |
IL (2) | IL149368A0 (de) |
MX (1) | MXPA02004224A (de) |
NO (1) | NO328015B1 (de) |
NZ (1) | NZ518451A (de) |
PT (1) | PT1228024E (de) |
SE (1) | SE9903930D0 (de) |
WO (1) | WO2001030734A1 (de) |
ZA (1) | ZA200203050B (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2852958B1 (fr) * | 2003-03-25 | 2005-06-24 | Fournier Lab Sa | Nouveaux derives de benzenesulfonamides et leur utilisation en therapeutique |
BRPI0408689B8 (pt) * | 2003-03-25 | 2021-05-25 | Laboratoires Fournier S A | derivados de benzenosulfonamida, método para preparação e utilização disso para o tratamento da dor |
PL1670458T3 (pl) | 2003-10-08 | 2007-05-31 | Bayer Schering Pharma Ag | 1-amino-2-hydroksy-podstawione pochodne tetrahydronaftalenu, sposób ich wytwarzania i ich zastosowanie jako środków hamujących zapalenie |
US7638515B2 (en) | 2003-10-08 | 2009-12-29 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
US7662821B2 (en) | 2003-10-08 | 2010-02-16 | Bayer Schering Pharma Ag | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
US20080153859A1 (en) | 2004-04-05 | 2008-06-26 | Hartmut Rehwinkel | Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
DE102005017316A1 (de) * | 2005-04-14 | 2006-10-19 | Schering Ag | Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
EP1834948A1 (de) | 2006-03-15 | 2007-09-19 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
EP2070903A1 (de) | 2007-12-12 | 2009-06-17 | Laboratorios del Dr. Esteve S.A. | Mikrowellengestützte Ringöffnungsreaktion |
EP2070904A1 (de) | 2007-12-12 | 2009-06-17 | Laboratorios Del. Dr. Esteve, S.A. | Rhodium-Phosphor-Komplexe und ihre Verwendung bei Ringöffnungsreaktionen |
KR101229822B1 (ko) | 2008-03-04 | 2013-02-05 | 연세대학교 산학협력단 | 혈관신생 억제용 약제학적 조성물 |
EP2098511A1 (de) * | 2008-03-07 | 2009-09-09 | Solvias AG | Verfahren zur Herstellung von Verbindungen mit einer Hydronaphtalinstruktur mit einem asymmetrisch substituierten Benzolring |
JP5656364B2 (ja) * | 2009-04-20 | 2015-01-21 | 株式会社トクヤマ | ナフトピラン誘導体の製造方法 |
EA201290697A1 (ru) * | 2010-01-27 | 2013-02-28 | Такеда Фармасьютикал Компани Лимитед | Соединения для подавления повреждения периферических нервов, вызванного противораковым агентом |
JP6236785B2 (ja) * | 2012-02-28 | 2017-11-29 | 株式会社リコー | アリールアミン化合物、有機el用材料およびその製造方法 |
CN105399752B (zh) * | 2015-11-04 | 2019-03-15 | 云南民族大学 | 一种新型化合物及其制备方法和应用 |
US11560384B2 (en) | 2017-05-04 | 2023-01-24 | University Of Utah Research Foundation | Benzonorbornadiene derivatives and reactions thereof |
CN108863855B (zh) * | 2018-05-29 | 2020-12-15 | 云南民族大学 | 一种合成(1r,2s)-1,2-二氢化萘-1,2-二胺衍生物的方法 |
CN111471005B (zh) * | 2020-05-21 | 2023-04-07 | 南方科技大学 | 一种吲哚-二氢化萘类化合物及其制备方法和应用 |
CN116459873A (zh) * | 2022-01-12 | 2023-07-21 | 万华化学集团股份有限公司 | 一种烯属不饱和化合物羰基化催化剂及其制备方法、应用 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CA2301870A1 (en) * | 1997-08-27 | 1999-03-04 | Kyowa Hakko Kogyo Co., Ltd. | Process for preparing optically active 1,2-diols |
-
1999
- 1999-10-29 SE SE9903930A patent/SE9903930D0/xx unknown
-
2000
- 2000-10-26 US US09/763,759 patent/US6525068B1/en not_active Expired - Fee Related
- 2000-10-26 CN CNB008177481A patent/CN1231439C/zh not_active Expired - Fee Related
- 2000-10-26 CA CA002387675A patent/CA2387675C/en not_active Expired - Fee Related
- 2000-10-26 ES ES00975109T patent/ES2225253T3/es not_active Expired - Lifetime
- 2000-10-26 NZ NZ518451A patent/NZ518451A/en unknown
- 2000-10-26 MX MXPA02004224A patent/MXPA02004224A/es active IP Right Grant
- 2000-10-26 DE DE60013471T patent/DE60013471T2/de not_active Expired - Lifetime
- 2000-10-26 EP EP00975109A patent/EP1228024B1/de not_active Expired - Lifetime
- 2000-10-26 AU AU13206/01A patent/AU776118B2/en not_active Ceased
- 2000-10-26 EP EP04015462A patent/EP1498406A1/de not_active Withdrawn
- 2000-10-26 PT PT00975109T patent/PT1228024E/pt unknown
- 2000-10-26 BR BR0015117-3A patent/BR0015117A/pt not_active Application Discontinuation
- 2000-10-26 IL IL14936800A patent/IL149368A0/xx unknown
- 2000-10-26 WO PCT/SE2000/002090 patent/WO2001030734A1/en active IP Right Grant
- 2000-10-26 JP JP2001533091A patent/JP2003512446A/ja active Pending
- 2000-10-26 AT AT00975109T patent/ATE275120T1/de not_active IP Right Cessation
- 2000-10-26 KR KR1020027005436A patent/KR100741177B1/ko not_active IP Right Cessation
-
2002
- 2002-04-17 ZA ZA200203050A patent/ZA200203050B/en unknown
- 2002-04-25 IL IL149368A patent/IL149368A/en not_active IP Right Cessation
- 2002-04-25 NO NO20021968A patent/NO328015B1/no not_active IP Right Cessation
- 2002-11-28 HK HK02108588.9A patent/HK1047083B/zh not_active IP Right Cessation
- 2002-12-12 US US10/317,183 patent/US6784210B2/en not_active Expired - Fee Related
-
2004
- 2004-05-28 US US10/855,783 patent/US7420003B2/en not_active Expired - Fee Related
-
2008
- 2008-07-28 US US12/219,752 patent/US20080300271A1/en not_active Abandoned
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