SE9801474D0 - Quinoline Derivatives - Google Patents

Quinoline Derivatives

Info

Publication number
SE9801474D0
SE9801474D0 SE9801474A SE9801474A SE9801474D0 SE 9801474 D0 SE9801474 D0 SE 9801474D0 SE 9801474 A SE9801474 A SE 9801474A SE 9801474 A SE9801474 A SE 9801474A SE 9801474 D0 SE9801474 D0 SE 9801474D0
Authority
SE
Sweden
Prior art keywords
propyl
iso
butyl
formula
ethyl
Prior art date
Application number
SE9801474A
Other languages
English (en)
Swedish (sv)
Inventor
Anders Bjoerk
Stig Joensson
Tomas Fex
Gunnar Hedlund
Original Assignee
Active Biotech Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Active Biotech Ab filed Critical Active Biotech Ab
Priority to SE9801474A priority Critical patent/SE9801474D0/xx
Publication of SE9801474D0 publication Critical patent/SE9801474D0/xx
Priority to US09/296,519 priority patent/US6077851A/en
Priority to OA1200000301A priority patent/OA11547A/en
Priority to PL99343420A priority patent/PL190441B1/pl
Priority to DE69904162T priority patent/DE69904162T2/de
Priority to UA2000085078A priority patent/UA60354C2/uk
Priority to NZ506641A priority patent/NZ506641A/en
Priority to HU0102084A priority patent/HU227709B1/hu
Priority to IDW20002183A priority patent/ID26277A/id
Priority to ES99947036T priority patent/ES2188242T3/es
Priority to IL13816099A priority patent/IL138160A0/xx
Priority to RU2000129672/04A priority patent/RU2197481C2/ru
Priority to EEP200000613A priority patent/EE04275B1/xx
Priority to TR2000/03061T priority patent/TR200003061T2/xx
Priority to YUP-612/00A priority patent/RS50029B/sr
Priority to MEP-2000-612A priority patent/ME00870B/me
Priority to EP99947036A priority patent/EP1073639B1/en
Priority to CZ20003849A priority patent/CZ297439B6/cs
Priority to JP2000545838A priority patent/JP4045069B2/ja
Priority to AT99947036T priority patent/ATE228505T1/de
Priority to PT99947036T priority patent/PT1073639E/pt
Priority to PCT/SE1999/000676 priority patent/WO1999055678A1/en
Priority to CN99805581A priority patent/CN1113057C/zh
Priority to DK99947036T priority patent/DK1073639T3/da
Priority to BRPI9909925-0A priority patent/BR9909925B1/pt
Priority to CA002329788A priority patent/CA2329788C/en
Priority to AU43013/99A priority patent/AU747550B2/en
Priority to APAP/P/2000/001933A priority patent/AP1293A/en
Priority to KR1020007011944A priority patent/KR100571534B1/ko
Priority to IL138160A priority patent/IL138160A/en
Priority to IS5615A priority patent/IS2082B/is
Priority to ZA200004601A priority patent/ZA200004601B/en
Priority to NO20005254A priority patent/NO315606B1/no
Priority to HR20000726A priority patent/HRP20000726B1/xx
Priority to HK01105489A priority patent/HK1036618A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE9801474A 1998-04-27 1998-04-27 Quinoline Derivatives SE9801474D0 (sv)

Priority Applications (35)

Application Number Priority Date Filing Date Title
SE9801474A SE9801474D0 (sv) 1998-04-27 1998-04-27 Quinoline Derivatives
US09/296,519 US6077851A (en) 1998-04-27 1999-04-22 Quinoline derivatives
KR1020007011944A KR100571534B1 (ko) 1998-04-27 1999-04-26 퀴놀린 유도체
EP99947036A EP1073639B1 (en) 1998-04-27 1999-04-26 Quinoline derivatives
AT99947036T ATE228505T1 (de) 1998-04-27 1999-04-26 Chinolinderivate
DE69904162T DE69904162T2 (de) 1998-04-27 1999-04-26 Chinolinderivate
UA2000085078A UA60354C2 (uk) 1998-04-27 1999-04-26 Похідні хіноліну, спосіб їх одержання (варіанти) та спосіб лікування ссавців
NZ506641A NZ506641A (en) 1998-04-27 1999-04-26 Quinoline derivatives useful in the treatment of autoimmune disorders
HU0102084A HU227709B1 (en) 1998-04-27 1999-04-26 Quinoline derivatives, process for producing them and pharmaceutical compositions containing them
IDW20002183A ID26277A (id) 1998-04-27 1999-04-26 Turunan-turunan kuinolina
ES99947036T ES2188242T3 (es) 1998-04-27 1999-04-26 Derivados de quinolina.
IL13816099A IL138160A0 (en) 1998-04-27 1999-04-26 Quinoline derivatives
RU2000129672/04A RU2197481C2 (ru) 1998-04-27 1999-04-26 Производные хинолина
EEP200000613A EE04275B1 (et) 1998-04-27 1999-04-26 Kinoliini derivaadid, nende valmistamismeetodid, kasutamine ja farmatseutilised kompositsioonid
TR2000/03061T TR200003061T2 (tr) 1998-04-27 1999-04-26 Kinolin türevleri
YUP-612/00A RS50029B (sr) 1998-04-27 1999-04-26 Derivati hinolina
MEP-2000-612A ME00870B (me) 1998-04-27 1999-04-26 Derivati hinolina
OA1200000301A OA11547A (en) 1998-04-27 1999-04-26 Quinoline derivatives.
CZ20003849A CZ297439B6 (cs) 1998-04-27 1999-04-26 Deriváty chinolinu
JP2000545838A JP4045069B2 (ja) 1998-04-27 1999-04-26 キノリン誘導体
PL99343420A PL190441B1 (pl) 1998-04-27 1999-04-26 Nowe pochodne 1-metylo-2-okso-chinolino-3-karboksyamidu zawierające je kompozycje farmaceutyczne oraz sposób ich wytwarzania
PT99947036T PT1073639E (pt) 1998-04-27 1999-04-26 Derivados de quinolina
PCT/SE1999/000676 WO1999055678A1 (en) 1998-04-27 1999-04-26 Quinoline derivatives
CN99805581A CN1113057C (zh) 1998-04-27 1999-04-26 喹啉衍生物
DK99947036T DK1073639T3 (da) 1998-04-27 1999-04-26 Chinolinderivater
BRPI9909925-0A BR9909925B1 (pt) 1998-04-27 1999-04-26 derivados de quinolina, composições farmacêuticas, e, processo para a fabricação de derivados de quinolina.
CA002329788A CA2329788C (en) 1998-04-27 1999-04-26 Quinoline derivatives
AU43013/99A AU747550B2 (en) 1998-04-27 1999-04-26 Quinoline derivatives
APAP/P/2000/001933A AP1293A (en) 1998-04-27 1999-04-26 Quinoline derivatives.
IL138160A IL138160A (en) 1998-04-27 2000-08-30 Quinoline derivatives
IS5615A IS2082B (is) 1998-04-27 2000-08-31 Kvínólínafleiður
ZA200004601A ZA200004601B (en) 1998-04-27 2000-09-01 Quinoline derivatives.
NO20005254A NO315606B1 (no) 1998-04-27 2000-10-19 Kinolinderivater
HR20000726A HRP20000726B1 (en) 1998-04-27 2000-10-26 Quinoline derivatives
HK01105489A HK1036618A1 (en) 1998-04-27 2001-08-07 Quinoline derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9801474A SE9801474D0 (sv) 1998-04-27 1998-04-27 Quinoline Derivatives

Publications (1)

Publication Number Publication Date
SE9801474D0 true SE9801474D0 (sv) 1998-04-27

Family

ID=20411103

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9801474A SE9801474D0 (sv) 1998-04-27 1998-04-27 Quinoline Derivatives

Country Status (33)

Country Link
EP (1) EP1073639B1 (sr)
JP (1) JP4045069B2 (sr)
KR (1) KR100571534B1 (sr)
CN (1) CN1113057C (sr)
AP (1) AP1293A (sr)
AT (1) ATE228505T1 (sr)
AU (1) AU747550B2 (sr)
BR (1) BR9909925B1 (sr)
CA (1) CA2329788C (sr)
CZ (1) CZ297439B6 (sr)
DE (1) DE69904162T2 (sr)
DK (1) DK1073639T3 (sr)
EE (1) EE04275B1 (sr)
ES (1) ES2188242T3 (sr)
HK (1) HK1036618A1 (sr)
HR (1) HRP20000726B1 (sr)
HU (1) HU227709B1 (sr)
ID (1) ID26277A (sr)
IL (2) IL138160A0 (sr)
IS (1) IS2082B (sr)
ME (1) ME00870B (sr)
NO (1) NO315606B1 (sr)
NZ (1) NZ506641A (sr)
OA (1) OA11547A (sr)
PL (1) PL190441B1 (sr)
PT (1) PT1073639E (sr)
RS (1) RS50029B (sr)
RU (1) RU2197481C2 (sr)
SE (1) SE9801474D0 (sr)
TR (1) TR200003061T2 (sr)
UA (1) UA60354C2 (sr)
WO (1) WO1999055678A1 (sr)
ZA (1) ZA200004601B (sr)

Families Citing this family (45)

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SE0002320D0 (sv) * 1999-10-25 2000-06-21 Active Biotech Ab Malignant tumors
SE0201778D0 (sv) * 2002-06-12 2002-06-12 Active Biotech Ab Process for the manufacture of quinoline derivatives
KR100908655B1 (ko) 2002-11-27 2009-07-21 엘지디스플레이 주식회사 데이터 공급시간의 변조방법과 이를 이용한액정표시장치의 구동방법 및 장치
SE0400235D0 (sv) * 2004-02-06 2004-02-06 Active Biotech Ab New composition containing quinoline compounds
SE0401578D0 (sv) * 2004-06-18 2004-06-18 Active Biotech Ab Novel compounds
US7838522B2 (en) 2004-11-17 2010-11-23 Ares Trading S.A. Benzothiazole formulations and use thereof
CA2589367C (en) 2004-12-21 2015-02-03 Laboratoires Serono S.A. Sulfonyl amino cyclic derivatives and use thereof
WO2006079653A1 (en) 2005-01-31 2006-08-03 Laboratoires Serono S.A. N-hydroxyamide derivatives and use thereof
BRPI0613042A2 (pt) 2005-07-15 2010-12-14 Serono Lab inibidores de jnk para o tratamento de endometriose
KR20080044836A (ko) 2005-07-15 2008-05-21 라보라뚜와르 세로노 에스. 에이. 자궁내막증 치료용 jnk 억제제
AU2006286489B2 (en) 2005-09-01 2012-08-09 Ares Trading S.A. Treatment of optic neuritis
NZ567088A (en) * 2005-10-19 2012-06-29 Teva Pharma Crystals of laquinimod sodium, and process for the manufacture thereof
KR101495327B1 (ko) * 2006-06-12 2015-02-24 테바 파마슈티컬 인더스트리즈 리미티드 안정한 라퀴니모드 제제
WO2009082471A1 (en) 2007-12-20 2009-07-02 Teva Pharmaceutical Industries, Ltd. Stable laquinimod preparations
WO2010028015A2 (en) * 2008-09-03 2010-03-11 Auspex Pharmaceuticals, Inc 2-oxo-1,2-dihydro-quinoline modulators of immune function
MX2012001333A (es) * 2009-07-30 2012-06-01 Teva Pharma Tratamiento de la enfermedad de crohn con la laquinimod.
EP3064206B1 (en) 2009-08-10 2019-03-20 Active Biotech AB Treatment of huntington's disease using laquinimod
AU2011223697B2 (en) * 2010-03-03 2016-07-14 Teva Pharmaceutical Industries Ltd. Treatment of rheumatoid arthritis with a combination of laquinimod and methotrexate
NZ602512A (en) * 2010-03-03 2014-07-25 Teva Pharma Treatment of lupus arthritis using laquinimod
EA201290837A1 (ru) * 2010-03-03 2013-05-30 Тева Фармасьютикал Индастриз Лтд. Лечение волчаночного нефрита с применением лаквинимода
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PT2590949E (pt) * 2010-07-09 2016-03-07 Active Biotech Ab Método para o fabrico de quinolina-3-carboxamidas
WO2012006538A1 (en) 2010-07-09 2012-01-12 Teva Pharmaceutical Industries Ltd. Deuterated n-ethyl-n-phenyl-1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide, salts and uses thereof
CN102985090B (zh) * 2010-07-09 2014-11-26 泰华制药工业有限公司 5-氯-4-羟基-1-甲基-2-氧代-n-苯基-1,2-二氢喹啉-3-甲酰胺、其盐和用途
EP2444086A1 (en) 2010-10-22 2012-04-25 Almirall, S.A. Combinations comprising DHODH inhibitors and COX inhibitors
BR112014008731A2 (pt) 2011-10-12 2017-04-25 Teva Pharma tratamento de esclerose múltipla com combinação de laquinimode e fingolimode
JP2015505564A (ja) * 2012-02-03 2015-02-23 テバ ファーマシューティカル インダストリーズ リミティド 第一選択の抗TNEα療法に失敗したクローン病患者を治療するためのラキニモドの使用
KR20140138725A (ko) 2012-02-16 2014-12-04 테바 파마슈티컬 인더스트리즈 리미티드 N-에틸-n-페닐-1,2-디하이드로-4,5-디-하이드록시-1-메틸-2-옥소-3-퀴놀린카복사미드, 그의 제조 및 용도
TW201350467A (zh) 2012-05-08 2013-12-16 Teva Pharma N-乙基-4-羥基-1-甲基-5-(甲基(2,3,4,5,6-五羥基己基)胺基)-2-側氧-n-苯基-1,2-二氫喹啉-3-甲醯胺
TW201400117A (zh) * 2012-06-05 2014-01-01 Teva Pharma 使用拉喹莫德治療眼發炎疾病
TW201410244A (zh) 2012-08-13 2014-03-16 Teva Pharma 用於治療gaba媒介之疾病之拉喹莫德(laquinimod)
MX2015005632A (es) 2012-11-07 2016-02-05 Teva Pharma Sales de amina de laquinimod.
RU2545056C2 (ru) * 2012-12-10 2015-03-27 Государственное бюджетное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия" Министерства здавоохранения и социального развития Российской Федерации (ГБОУ ВПО ПГФА Минздравсоцразвития России) Противовоспалительное и анальгетическое средство на основе изопропиламида 1,2-дигидро-1н-2-оксоцинхониновой кислоты
AU2014216199A1 (en) * 2013-02-15 2015-09-03 Teva Pharmaceutical Industries Ltd. Treatment of progressive forms of multiple sclerosis with laquinimod
NZ630427A (en) 2013-03-14 2017-06-30 Teva Pharma Crystals of laquinimod sodium and improved process for the manufacture thereof
EP3137092A4 (en) 2014-04-29 2017-10-11 Teva Pharmaceutical Industries Ltd. Laquinimod for the treatment of relapsing-remitting multiple sclerosis (rrms) patients with a high disability status
AU2015316824B2 (en) 2014-09-23 2020-10-29 Active Biotech Ab Quinoline carboxamides for use in the treatment of multiple myeloma
NZ732704A (en) 2014-11-19 2022-01-28 Active Biotech Ab Quinoline carboxamides for use in the treatment of leukemia
CA3157394A1 (en) 2019-12-19 2021-06-24 Helena ERIKSSON Compounds for treatment of eye diseases associated with excessive vascularisation
WO2021175924A1 (en) 2020-03-03 2021-09-10 Active Biotech Ab Tasquinimod or a pharmaceutically acceptable salt thereof for use in combination therapy
AU2021275994A1 (en) * 2020-05-21 2022-12-22 Stemsynergy Therapeutics, Inc. Notch inhibitors and uses thereof
KR20230043916A (ko) 2020-07-23 2023-03-31 에라스무스 유니버시티 메디컬 센터 로테르담 골수증식성 신생물의 새로운 치료학적 표적으로서 s100 단백질
MX2023008016A (es) 2021-01-18 2023-07-13 Active Biotech Ab Tasquinimod o una sal farmaceutica aceptable para su uso en el tratamiento del sindrome mielodisplasico.
US20240285532A1 (en) 2021-05-25 2024-08-29 Active Biotech Ab A plurality of tasquinimod particles and use thereof
KR20240029029A (ko) 2021-07-02 2024-03-05 액티브 바이오테크 에이비 타스퀴니모드를 함유한 약학적 제품 및 이러한 제품의 순도 평가 방법

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IE52670B1 (en) * 1981-03-03 1988-01-20 Leo Ab Heterocyclic carboxamides,compositions containing such compounds,and processes for their preparation
GB9108547D0 (en) * 1991-04-22 1991-06-05 Fujisawa Pharmaceutical Co Quinoline derivatives

Also Published As

Publication number Publication date
ID26277A (id) 2000-12-14
IS2082B (is) 2006-02-15
RU2197481C2 (ru) 2003-01-27
IL138160A (en) 2006-04-10
NZ506641A (en) 2002-03-28
IL138160A0 (en) 2001-10-31
DE69904162D1 (de) 2003-01-09
AU747550B2 (en) 2002-05-16
EP1073639A1 (en) 2001-02-07
PT1073639E (pt) 2003-04-30
CA2329788A1 (en) 1999-11-04
EP1073639B1 (en) 2002-11-27
HUP0102084A3 (en) 2002-12-28
NO20005254D0 (no) 2000-10-19
JP4045069B2 (ja) 2008-02-13
ATE228505T1 (de) 2002-12-15
UA60354C2 (uk) 2003-10-15
CA2329788C (en) 2004-11-23
HU227709B1 (en) 2011-12-28
JP2002513006A (ja) 2002-05-08
KR100571534B1 (ko) 2006-04-14
CN1113057C (zh) 2003-07-02
IS5615A (is) 2000-08-31
PL343420A1 (en) 2001-08-13
AP2000001933A0 (en) 2000-12-31
HRP20000726A2 (en) 2001-04-30
ME00870B (me) 2008-11-28
RS50029B (sr) 2008-11-28
DE69904162T2 (de) 2003-08-21
PL190441B1 (pl) 2005-12-30
CZ20003849A3 (cs) 2001-03-14
CN1298393A (zh) 2001-06-06
CZ297439B6 (cs) 2006-12-13
DK1073639T3 (da) 2003-03-24
OA11547A (en) 2004-05-24
WO1999055678A1 (en) 1999-11-04
ZA200004601B (en) 2002-02-27
HK1036618A1 (en) 2002-01-11
TR200003061T2 (tr) 2001-01-22
HUP0102084A2 (hu) 2001-11-28
AU4301399A (en) 1999-11-16
NO315606B1 (no) 2003-09-29
BR9909925B1 (pt) 2010-09-21
EE200000613A (et) 2002-04-15
HRP20000726B1 (en) 2009-04-30
ES2188242T3 (es) 2003-06-16
NO20005254L (no) 2000-12-27
EE04275B1 (et) 2004-04-15
YU61200A (sh) 2003-07-07
AP1293A (en) 2004-08-30
BR9909925A (pt) 2001-01-09

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